A possible mechanism for the decrease in serum thyroxine level by phenobarbital in rodents

Toxicology and Applied Pharmacology

Volumn 249, Issue 3, 2010, Pages 238-246

  Kato, Yoshihisa ^a   Suzuki, Hiroshi ^b   Haraguchi, Koichi ^c   Ikushiro, Shinichi ^d   Ito, Yoshihiko ^b   Uchida, Shinya ^b   Yamada, Shizuo ^b   Degawa, Masakuni ^b  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

^c DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^d TOYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Phenobarbital; Rodent; Thyroxine; UDP glucuronosyltransferase

Indexed keywords

GLUCURONIDE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A6; GLUCURONOSYLTRANSFERASE 2B1; GLYCOSYLTRANSFERASE; LIOTHYRONINE; PHENOBARBITAL; THYROTROPIN; THYROXINE; THYROXINE I 125; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BLOOD SAMPLING; BRAIN; CECUM; CEREBELLUM; CONTROLLED STUDY; DOWN REGULATION; DUODENUM; ENZYME ACTIVITY; FREE THYROXINE INDEX; GUINEA PIG; HAMSTER; HEART; HYPOPHYSIS; ILEUM; JEJUNUM; KIDNEY; LIOTHYRONINE BLOOD LEVEL; LIVER; LIVER LEVEL; LUNG; MALE; MOUSE; NONHUMAN; PLASMA CLEARANCE; PROSTATE; RADIOACTIVITY; RAT; RODENT; SEMINAL VESICLE; SPECIES DIFFERENCE; SPLEEN; STEADY STATE; STOMACH; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND; TESTIS; THYMUS; THYROID GLAND; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TISSUE DISTRIBUTION; UPREGULATION;

ANIMALS; CRICETINAE; GLUCURONIDES; GUINEA PIGS; HYPNOTICS AND SEDATIVES; LIVER; MALE; MICE; PHENOBARBITAL; RATS; RATS, WISTAR; SULFOTRANSFERASES; THYROXINE; TRIIODOTHYRONINE;

ANIMALIA; CAVIA; CRICETINAE; MUS; RATTUS; RODENTIA;

EID: 78149415855     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.09.024     Document Type: Article

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