Purine receptors modulate chondrocyte extracellular inorganic pyrophosphate production

Osteoarthritis and Cartilage

Volumn 18, Issue 11, 2010, Pages 1496-1501

  Rosenthal, A K ^a   Hempel, D ^a   Kurup, I V ^a   Masuda, I ^a   Ryan, L M ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Articular cartilage; ATP; Biomineralization; Chondrocytes; Purine receptors

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; CALCIUM ION; COMPLEMENTARY DNA; CYCLIC AMP; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; PURINERGIC P2 RECEPTOR; PURINERGIC RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PURINERGIC RECEPTOR STIMULATING AGENT; PYROPHOSPHATE; RNA; SURAMIN; THAPSIGARGIN;

ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; BIOMINERALIZATION; CALCIUM MOBILIZATION; CARTILAGE CELL; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SWINE;

ADENOSINE DIPHOSPHATE; ANIMALS; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; CYCLIC AMP; DIPHOSPHATES; PURINERGIC P1 RECEPTOR AGONISTS; PURINERGIC P2 RECEPTOR AGONISTS; PURINERGIC P2 RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC; RNA, MESSENGER; SURAMIN; SWINE;

EID: 78149415406     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.08.004     Document Type: Article

References (49)

1. Masuda I., Hirose J. Animal models of pathologic calcification. Curr Opin Rheumatol 2002, 14:287-291.
2. Ho A., Johnson M., Kingsley D. Role of the mouse ank gene in tissue calcification and arthritis. Science 2000, 289:265-270.
3. Okawa A., Nakamura I., Goto S., Moriya H., Nakamura Y., Ikegawa S. Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine. Nat Genet 1998, 19:271-273.
4. Hessle L., Johnson K., Anderson C., Nariwawa S., Sali A., Goding J., et al. Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralizatoin. Proc Natl Acad Sci USA 2002, 99:9445-9449.
5. Rutsch F., Schaurte P., Kalhoff H., Petrarulo M., August C., Dickaman L. Low levels of urinary inorganic pyrophosphate indicating systemic pyrophosphate deficiency in a boy with idiopathic infantile arterial calcification. Acta Paediatr 2000, 89:1265-1269.
6. Rutsch F., Vaingankar S., Johnson K., Goldfine I., Maddux B., Schaurte P., et al. PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification. Am J Pathol 2001, 158:543-554.
7. Rachow J., Ryan L., McCarty D., Halverson P. Synovial fluid inorganic pyrophosphate concentration and nucelotide pyrophosphohydrolase activity in basic calcium phsophate deposition arthropathy and Milwaukee shoulder syndrome. Arthritis Rheum 1988, 31:408-413.
8. Ryan L., Kozin F., McCarty D. Quantification of human plasma inorganic pyrophosphate. I. Normal values in osteoarthritis and calcium pyrophosphate dihydrate crystal deposition disease. Arthritis Rheum 1979, 22:886-891.
9. Russell G., Bisaz S., Donath A., Morgan D., Fleisch H. Inorganic pyrophosphate in plasma in normal persons and in patients with hypophosphatasia, osteogenesis imperfecta, and other disorders of bone. Clin Investig 1971, 50:961-969.
10. Fedde K., Blair L., Silverstein J., Coburn S., Ryan L., Weinstein R., et al. Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia. J Bone Miner Res 1999, 14:2015-2026.
11. Doherty M., Chuck A., Hosking D., Hamilton E. Inorganic pyrophosphate in metabolic diseases predisposing to calcium pyrophosphate dihydrate crystal deposition. Arthritis Rheum 1991, 34:1297-1303.
12. Ryan L., Cheung H., McCarty D. Release of pyrophosphate by normal mammalian articular hyaline and fibrocartilage in organ culture. Arthritis Rheum 1981, 124:1522-1527.
13. Howell D., Muniz O., Pita J., Enis J. Extrusion of pyrophosphate into extracellular media by osteoarthritic cartilage incubates. J Clin Invest 1975, 56:1473-1480.
14. Ryan L., Rosenthal A. Metabolism of extracellular pyrophosphate. Curr Opin Rheumatol 2003, 15:311-314.
15. Rosenthal A., McCarty B., Cheung H., Ryan L. A comparison of the effect of transforming growth factor β1 on pyrophosphate elaboration from various articular tissues. Arthritis Rheum 1993, 36:539-542.
16. Ryan L., Kurup I., Rosenthal A., McCarty D. Stimulation of inorganic pyrophosphate elaboratoin by cultured cartilage and chondrocytes. Arch Biochem Biophys 1989, 272:393-399.
17. Graff R., Lazarowksi E., Banes A., Lee G. ATP release by mechanically loaded porcine chondrons in pellet culture. Arthritis Rheum 2000, 43:1571-1579.
18. Mistry D., Chambers M., Mason R. The role of adenosine in chondrocyte death in murine osteoarthritis and in a murine chondrocyte cell line. Osteoarthritis Cartilage 2006, 14:486-495.
19. Koolpe M., Pearson D., Benton H. Expression of both P1 and P2 purine receptor genes by human articular chondrocytes and profile of ligand-mediated prostaglandin E2 release. Arthritis Rheum 1999, 42:258-267.
20. Chowdhury T., Knight M. Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression. J Cell Physiol 2006, 209:845-853.
21. Kudirka J., Panupinthu N., Tesseyman M., Dixon S., Bernier S. P2Y nucleotide receptor signaling through MAPK/ERK is regulated by extracellular matrix: involvement of B3 integrins. J Cell Physiol 2007, 213:54-64.
22. Katz S., Boland R., Santilan G. Modulation of ERK1/2 and p38 MAPK signaling pathways by ATP in osteoblasts: involvement of mechanical stress-activated calcium influx, PKC and Src activation. Int J Biochem Cell Biol 2006, 38:2082-2091.
23. Hiken J., Steinberg T. ATP downregulates P2X7 and inhibits osteoclast formation in RAW cells. Am J Physiol Cell Physiol 2004, 287:C403-C412.
24. Orriss I., Knight G., Ransinghe S., et al. Osteoblast responses to nucleotides increase during differentiation. Bone 2006, 39:300-309.
25. Kahner B., Shankar H., Murugappan S., Prasad G., Kunapuli S. Nucleotide receptor signaling in platelets. J Thromb Haemost 2006, 4:2317-2326.
26. Iwamoto T., Umemura S., Toya Y., Uchibori T., Kogi K., Takagi N., et al. Identification of adenosine A2 receptor-cAMP system in human aortic endothelial cells. Biochem Biophys Res Commun 1994, 199:905-910.
27. Ryan L.M., Kurup I.V., Cheung H.S. Transduction mechanisms of porcine chondrocyte inorganic pyrophosphate elaboration. Arthritis Rheum 1999, 42(3):555-560.
28. Berenbaum F., Humbert L., Bereziat G., Thirion S. Concomitant recruitment of ERD1/2 and p38 MAPK signaling pathway is required for activation of cytoplasmic phospholipase A2 via ATP in articular chondrocytes. J Biol Chem 2003, 278:13680-13687.
29. Varani K., Mattei M., Vincenzi F., Gessi S., Merighi S., Pellati A., et al. Characterization of adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes exposed to low frequency low energy pulsed electromagnetic fields. Osteoarthritis Cartilage 2008, 16:292-304.
30. Knight M., McGlashan S., Garcia M., Jensen C., Poole C. Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium?. J Anat 2009, 214:275-283.
31. Elfervig M., Graff R., Lee G., Kelley S., Sood A., Banes A. ATP induces Ca2+ signaling in human chondrons cultured in three-dimensional agarose films. Osteoarthritis Cartilage 2001, 9:518-526.
32. Koolpe M., Benton H. Calcium-mobilizing purine receptors on the surface of mammalian articular chondrocytes. J Bone Joint Surg 1997, 15:204-213.
33. Cheung H., Ryan L. A method of determining DNA and chondrocyte content of articular cartilage. Anal Biochem 1981, 116:93-97.
34. Cheng T.-C., Benton H. The intracellular Ca2+ pump inhibitors thapsigargin and cyclopiazonic acid induce stress proteins in mammalian chondrocytes. Biochem J 1994, 301:563-568.
35. Bowler W., Dixon D., Halleux C., Maier R., Bilbe G., Fraser W., et al. Signaling in human osteoblasts by extracellular nucleotides. Their weak induction of the c-fos proto-oncogene via Ca mobilization is strongly potentiated by a parathyroid hormone/cAMP-dependent protein kinase pathway independently of mitogen-activated protein kinase. J Biol Chem 1999, 274:14315-14324.
36. Strehlau J., Pavlakis M., Lipman M., Shapiro M., Vasconcellos L., Harmon W., et al. Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation. Proc Natl Acad Sci USA 1997, 94(2):695-700.
37. Cheung C., Suhadolinik R. Analysis of inorganic pyrophosphate at the picomole level. Anal Biochem 1977, 83:61-63.
38. Newby A. How does dipyridiamole elevate extracellular adenosine concentration?. Biochem J 1986, 237:845-851.
39. Ryan L., Rachow J., McCarty D. Synovial fluid ATP: a potential substrate for the production of inorganic pyrophosphate. J Rheumatol 1991, 18:716-720.
40. Pelegrin P., Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1B release by the ATP-gated P2X7 receptor. EMBO J 2006, 25:5071-5082.
41. Braunstein G., Roman R., Clancy J., Kudlow B., Taylor A., Shylonsky V., et al. Cystic fibrosis transmembrane conductance regulator facilitates ATP release by stimulating a separate ATP release channel for autocrine control of cell volume regulation. J Biol Chem 2000, 276:6621-6630.
42. Liu H.-T., Sabirov R., Okada Y., Burnstock G., Arnett T.R. Oxygen-glucose deprivation induces ATP release via maxi-anion channels in astrocytes. Purinergic Signal 2008, 4:147-154.
43. Bodin P., Burnstock G. Evidence that release of adenosine triphosphate from endothelial cells during increased shear stress is vesicular. J Cardiovasc Pharmacol 2001, 38:900-908.
44. Bozzo J., Hernandez M., Galan A., Heras M., Ordinas A., Escolar G. Impaired anti-platelet effects of aspirin associated with hypoxia and ATP release from erythrocytes. Eur J Clin Invest 1999, 29:438-444.
45. Rapapaort E., Fontaine J. Anticancer activities of adenine nucleotides in mice are mediated through expansion of erythrocyte ATP pools. Proc Natl Acad Sci USA 1989, 86:1662-1666.
46. Ryan L.M., McCarty D.J. Calcium pyrophosphate crystal deposition disease, pseudogout, and articular chondrocalcinosis. Arthritis and Allied Conditions 1997, 2103-2126. Williams & Wilkins, Baltimore. 13th edn. W. Koopman (Ed.).
47. Pingguan-Murphy B., El-Azzeh M., Bader D., Knight M. Cyclic compression of chondrocytes modulates a purinergic calcium signalling pathway in a strain rate- and frequency-dependent manner. J Cell Physiol 2006, 209:389-397.
48. Millward-Sadler S., Wright M., Flatman P., Salter D. ATP in the mechanotransduction pathway of normal human chondrocytes. Biorheology 2004, 41:567-575.
49. Hamilton S., McMahon S. ATP as a peripheral mediator of pain. J Auton Nerv Syst 2000, 81:187-194.