Chemokine profile of synovial fluid from normal, osteoarthritis and rheumatoid arthritis patients: CCL25, CXCL10 and XCL1 recruit human subchondral mesenchymal progenitor cells

Osteoarthritis and Cartilage

Volumn 18, Issue 11, 2010, Pages 1458-1466

  Endres, M ^a,b   Andreas, K ^b   Kalwitz, G ^a,b   Freymann, U ^a   Neumann, K ^a   Ringe, J ^b   Sittinger, M ^b   Haupl T ^b   Kaps, C ^a  

^a TRANSTISSUE TECHNOLOGIES GMBH   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Cartilage regeneration; Chemokine; Microfracture; Osteoarthritis; Stem cells; Synovial fluid

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; COMPLEMENTARY DNA; DISEASE MODIFYING ANTIRHEUMATIC DRUG; NONSTEROID ANTIINFLAMMATORY AGENT; RNA;

ADULT; ARTICLE; BONE; CARTILAGE; CELL MIGRATION; CHEMOTAXIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STEM CELL; MICROFRACTURE; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; TISSUE REGENERATION;

ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; CELL MIGRATION ASSAYS; CHEMOKINE CXCL10; CHEMOKINES; CHEMOKINES, C; CHEMOKINES, CC; CHEMOTAXIS; HUMANS; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STEM CELLS; OSTEOARTHRITIS; SYNOVIAL FLUID;

EID: 78149413791     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.08.003     Document Type: Article

References (46)

1. Steadman J.R., Rodkey W.G., Briggs K.K., Rodrigo J.J. The microfracture technique in the management of complete cartilage defects in the knee joint. Orthopade 1999, 28:26-32.
2. Steadman J.R., Briggs K.K., Rodrigo J.J., Kocher M.S., Gill T.J., Rodkey W.G. Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy 2003, 19:477-484.
3. Steadman J.R., Rodkey W.G., Briggs K.K. Microfracture to treat full-thickness chondral defects: surgical technique, rehabilitation, and outcomes. J Knee Surg 2002, 15:170-176.
4. Shapiro F., Koide S., Glimcher M.J. Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J Bone Joint Surg Am 1993, 75:532-553.
5. Frisbie D.D., Oxford J.T., Southwood L., Trotter G.W., Rodkey W.G., Steadman J.R., et al. Early events in cartilage repair after subchondral bone microfracture. Clin Orthop Relat Res 2003, 407:215-227.
6. Buckwalter J.A. Articular cartilage injuries. Clin Orthop 2002, 402:21-37.
7. Buckwalter J.A., Brown T.D. Joint injury, repair, and remodeling: roles in post-traumatic osteoarthritis. Clin Orthop Relat Res 2004, 423:7-16.
8. Skoog V., Widenfalk B., Ohlsen L., Wasteson A. The effect of growth factors and synovial fluid on chondrogenesis in perichondrium. Scand J Plast Reconstr Surg Hand Surg 1990, 24:89-95.
9. Hegewald A.A., Ringe J., Bartel J., Kruger I., Notter M., Barnewitz D., et al. Hyaluronic acid and autologous synovial fluid induce chondrogenic differentiation of equine mesenchymal stem cells: a preliminary study. Tissue Cell 2004, 36:431-438.
10. Endres M., Neumann K., Haupl T., Erggelet C., Ringe J., Sittinger M., et al. Synovial fluid recruits human mesenchymal progenitors from subchondral spongious bone marrow. J Orthop Res 2007, 25:1299-1307.
11. Neidel J., Schulze M., Sova L., Lindschau J. Practical significance of cytokine determination in joint fluid in patients with arthroses or rheumatoid arthritis. Z Orthop Ihre Grenzgeb 1996, 134:381-385.
12. Fernandes J.C., Martel-Pelletier J., Pelletier J.P. The role of cytokines in osteoarthritis pathophysiology. Biorheology 2002, 39:237-246.
13. Vergunst C.E., van de Sande M.G., Lebre M.C., Tak P.P. The role of chemokines in rheumatoid arthritis and osteoarthritis. Scand J Rheumatol 2005, 34:415-425.
14. Iwamoto T., Okamoto H., Toyama Y., Momohara S. Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients. Febs J 2008, 275:4448-4455.
15. Premack B.A., Schall T.J. Chemokine receptors: gateways to inflammation and infection. Nat Med 1996, 2:1174-1178.
16. Murphy P.M., Baggiolini M., Charo I.F., Hebert C.A., Horuk R., Matsushima K., et al. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev 2000, 52:145-176.
17. Borzi R.M., Mazzetti I., Marcu K.B., Facchini A. Chemokines in cartilage degradation. Clin Orthop Relat Res 2004, 427:S53-S61.
18. Cristino S., Piacentini A., Manferdini C., Codeluppi K., Grassi F., Facchini A., et al. Expression of CXC chemokines and their receptors is modulated during chondrogenic differentiation of human mesenchymal stem cells grown in three-dimensional scaffold: evidence in native cartilage. Tissue Eng Part A 2008, 14:97-105.
19. Baggiolini M. Chemokines in pathology and medicine. J Intern Med 2001, 250:91-104.
20. Honczarenko M., Le Y., Swierkowski M., Ghiran I., Glodek A.M., Silberstein L.E. Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors. Stem Cells 2006, 24:1030-1041.
21. Sordi V., Malosio M.L., Marchesi F., Mercalli A., Melzi R., Giordano T., et al. Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood 2005, 106:419-427.
22. Von Luttichau I., Notohamiprodjo M., Wechselberger A., Peters C., Henger A., Seliger C., et al. Human adult CD34-progenitor cells functionally express the chemokine receptors CCR1, CCR4, CCR7, CXCR5, and CCR10 but not CXCR4. Stem Cells Dev 2005, 14:329-336.
23. Ringe J., Strassburg S., Neumann K., Endres M., Notter M., Burmester G.R., et al. Towards in situ tissue repair: human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2. J Cell Biochem 2007, 101:135-146.
24. Neumann K., Dehne T., Endres M., Erggelet C., Kaps C., Ringe J., et al. Chondrogenic differentiation capacity of human mesenchymal progenitor cells derived from subchondral cortico-spongious bone. J Orthop Res 2008, 26:1449-1456.
25. Arnett F.C., Edworthy S.M., Bloch D.A., McShane D.J., Fries J.F., Cooper N.S., et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988, 31:315-324.
26. Altman R., Alarcon G., Appelrouth D., Bloch D., Borenstein D., Brandt K., et al. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum 1991, 34:505-514.
27. Chomczynski P. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 1993, 15:532-534.
28. Steadman J.R., Rodkey W.G., Rodrigo J.J. Microfracture: surgical technique and rehabilitation to treat chondral defects. Clin Orthop Relat Res 2001, 391:S362-S369.
29. Kruger J.P., Endres M., Neumann K., Haupl T., Erggelet C., Kaps C. Chondrogenic differentiation of human subchondral progenitor cells is impaired by rheumatoid arthritis synovial fluid. J Orthop Res 2010, 28:819-827.
30. Zhang S., Muneta T., Morito T., Mochizuki T., Sekiya I. Autologous synovial fluid enhances migration of mesenchymal stem cells from synovium of osteoarthritis patients in tissue culture system. J Orthop Res 2008, 26:1413-1418.
31. Ponte A.L., Marais E., Gallay N., Langonne A., Delorme B., Herault O., et al. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells 2007, 25:1737-1745.
32. Nedeau A.E., Bauer R.J., Gallagher K., Chen H., Liu Z.J., Velazquez O.C. A CXCL5- and bFGF-dependent effect of PDGF-B-activated fibroblasts in promoting trafficking and differentiation of bone marrow-derived mesenchymal stem cells. Exp Cell Res 2008, 314:2176-2186.
33. Kalwitz G., Endres M., Neumann K., Skriner K., Ringe J., Sezer O., et al. Gene expression profile of adult human bone marrow-derived mesenchymal stem cells stimulated by the chemokine CXCL7. Int J Biochem Cell Biol 2009, 41:649-658.
34. Croitoru-Lamoury J., Lamoury F.M., Zaunders J.J., Veas L.A., Brew B.J. Human mesenchymal stem cells constitutively express chemokines and chemokine receptors that can be upregulated by cytokines, IFN-beta, and Copaxone. J Interferon Cytokine Res 2007, 27:53-64.
35. Binger T., Stich S., Andreas K., Kaps C., Sezer O., Notter M., et al. Migration potential and gene expression profile of human mesenchymal stem cells induced by CCL25. Exp Cell Res 2009, 315:1468-1479.
36. Kalwitz G., Andreas K., Endres M., Neumann K., Notter M., Ringe J., et al. Chemokine profile of human serum from whole blood: migratory effects of CXCL-10 and CXCL-11 on human mesenchymal stem cells. Connect Tissue Res 2010, 51:113-122.
37. Chamberlain G., Wright K., Rot A., Ashton B., Middleton J. Murine mesenchymal stem cells exhibit a restricted repertoire of functional chemokine receptors: comparison with human. PLoS One 2008, 3:e2934.
38. Stich S., Loch A., Leinhase I., Neumann K., Kaps C., Sittinger M., et al. Human periosteum-derived progenitor cells express distinct chemokine receptors and migrate upon stimulation with CCL2, CCL25, CXCL8, CXCL12, and CXCL13. Eur J Cell Biol 2008, 87:365-376.
39. Kramer J., Bohrnsen F., Lindner U., Behrens P., Schlenke P., Rohwedel J. In vivo matrix-guided human mesenchymal stem cells. Cell Mol Life Sci 2006, 63:616-626.
40. Behrens P. Matrix-coupled microfracture - a new concept for cartilage defect repair. Arthroskopie 2005, 18:193-197.
41. Hoemann C.D., Sun J., McKee M.D., Chevrier A., Rossomacha E., Rivard G.E., et al. Chitosan-glycerol phosphate/blood implants elicit hyaline cartilage repair integrated with porous subchondral bone in microdrilled rabbit defects. Osteoarthritis Cartilage 2007, 15:78-89.
42. Chevrier A., Hoemann C.D., Sun J., Buschmann M.D. Chitosan-glycerol phosphate/blood implants increase cell recruitment, transient vascularization and subchondral bone remodeling in drilled cartilage defects. Osteoarthritis Cartilage 2007, 15:316-327.
43. Erggelet C., Neumann K., Endres M., Haberstroh K., Sittinger M., Kaps C. Regeneration of ovine articular cartilage defects by cell-free polymer-based implants. Biomaterials 2007, 28:5570-5580.
44. Erggelet C., Endres M., Neumann K., Morawietz L., Ringe J., Haberstroh K., et al. Formation of cartilage repair tissue in articular cartilage defects pretreated with microfracture and covered with cell-free polymer-based implants. J Orthop Res 2009, 27:1353-1360.
45. Zantop T., Petersen W. Arthroscopic implantation of a matrix to cover large chondral defect during microfracture. Arthroscopy 2009, 25:1354-1360.
46. Song H.Y., Lee M.J., Kim M.Y., Kim K.H., Lee I.H., Shin S.H., et al. Lysophosphatidic acid mediates migration of human mesenchymal stem cells stimulated by synovial fluid of patients with rheumatoid arthritis. Biochim Biophys Acta 2010, 1801:23-30.