Synovial fluid recruits human mesenchymal progenitors from subchondral spongious bone marrow

Journal of Orthopaedic Research

Volumn 25, Issue 10, 2007, Pages 1299-1307

  Endres, Michaela ^a   Neumann, Katja ^a   Häupl, Thomas ^b   Erggelet, Christoph ^c   Ringe, Jochen ^b   Sittinger, Michael ^b   Kaps, Christian ^a,b  

^a TRANSTISSUE TECHNOLOGIES GMBH   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cell recruitment; Chemotaxis; Microfracture; Osteoarthritis; Synovial fluid

Indexed keywords

ARTICLE; ARTICULAR CARTILAGE; BONE GRAFT; BONE MARROW; BONE PLATE; CELL CULTURE; CELL ISOLATION; CELL MIGRATION; CELL REGENERATION; CELL STIMULATION; CHEMOTAXIS; CONTROLLED STUDY; FEMALE; FRACTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; MESENCHYMAL STEM CELL; OSTEOARTHRITIS; OSTEOTOMY; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; TISSUE REPAIR;

ADULT; ARTHRITIS, RHEUMATOID; BONE MARROW CELLS; CHEMOTACTIC FACTORS; CHEMOTAXIS; FEMALE; HUMANS; KNEE JOINT; MALE; MESENCHYMAL STEM CELLS; MIDDLE AGED; OSTEOARTHRITIS; SYNOVIAL FLUID;

EID: 34948838346     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20394     Document Type: Article

References (33)

1. Galois L, Freyria AM, Grossin L, et al. 2004. Cartilage repair: surgical techniques and tissue engineering using polysaccharide- and collagen-based biomaterials. Biorheology 41:433-443.
2. Steadman JR, Briggs KK, Rodrigo JJ, et al. 2003. Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy 19:477-484.
3. Shapiro F, Koide S, Glimcher MJ., 1993. Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J Bone Joint Surg [Am] 75:532-553.
4. Gross AE., 2003. Cartilage resurfacing: filling defects. J Arthroplasty 18 (3 Suppl 1):14-17.
5. Frisbie DD, Oxford JT, Southwood L, et al. 2003. Early events in cartilage repair after subchondral bone microfracture. Clin Orthop Relat Res (407):215-227.
6. Frisbie DD, Trotter GW, Powers BE, et al. 1999. Arthroscopic subchondral bone plate microfracture technique augments healing of large chondral defects in the radial carpal bone and medial femoral condyle of horses. Vet Surg 28:242-255.
7. Robinson D, Nevo Z., 2001. Articular cartilage chondrocytes are more advantageous for generating hyaline-like cartilage than mesenchymal cells isolated from microfracture repairs. Cell Tissue Bank 2:23-30.
8. Fiedler J, Roderer G, Gunther KP, et al. 2002. BMP-2, BMP-4, and PDGF-bb stimulate chemotactic migration of primary human mesenchymal progenitor cells. J Cell Biochem 87:305-312.
9. Honczarenko M, Le Y, Swierkowski M, et al. 2006. Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors. Stem Cells 24:1030-1041.
10. Ruster B, Grace B, Seitz O, et al. 2005. Induction and detection of human mesenchymal stem cell migration in the 48-well reusable transwell assay. Stem Cells Dev 14:231-235.
11. Neuss S, Becher E, Woltje M, et al. 2004. Functional expression of HGF and HGF receptor/c-met in adult human mesenchymal stem cells suggests a role in cell mobilization, tissue repair, and wound healing. Stem Cells 22:405-414.
12. Okazaki R, Sakai A, Uezono Y, et al. 2001. Sequential changes in transforming growth factor (TGF)-beta1 concentration in synovial fluid and mRNA expression of TGF-beta1 receptors in chondrocytes after immobilization of rabbit knees. J Bone Miner Metab 19:228-235.
13. Hegewald AA, Ringe J, Bartel J, et al. 2004. Hyaluronic acid and autologous synovial fluid induce chondrogenic differentiation of equine mesenchymal stem cells: a preliminary study. Tissue Cell 36:431-438.
14. Lafeber FP, Vander Kraan PM, Huber-Bruning O, et al. 1993. Osteoarthritic human cartilage is more sensitive to transforming growth factor beta than is normal cartilage. Br J Rheumatol 32:281-286.
15. Chu CQ, Field M, Abney E, et al. 1991. Transforming growth factor-beta 1 in rheumatoid synovial membrane and cartilage/pannus junction. Clin Exp Immunol 86:380-386.
16. Blumenfeld I, Laufer D, Livne E. 1997. Effects of transforming growth factor-beta 1 and interleukin-1 alpha on matrix synthesis in osteoarthritic cartilage of the temporo-mandibular joint in aged mice. Mech Ageing Dev 95:101-111.
17. Arnett FC, Edworthy SM, Bloch DA, et al. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315-324.
18. Altman R, Alarcon G, Appelrouth D, et al. 1991. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum 34:505-514.
19. Lande R, Giacomini E, Serafini B, et al. 2004. Characterization and recruitment of plasmacytoid dendritic cells in synovial fluid and tissue of patients with chronic inflammatory arthritis. J Immunol 173:2815-2824.
20. Buckwalter JA, Brown TD., 2004. Joint injury, repair, and remodeling: roles in post-traumatic osteoarthritis. Clin Orthop Relat Res (423):7-16.
21. Buckwalter JA, Martin JA, Olmstead M, et al. 2003. Osteochondral repair of primate knee femoral and patellar articular surfaces: implications for preventing post-traumatic osteoarthritis. Iowa Orthop J 23:66-74.
22. Marcacci M, Berruto M, Brocchetta D, et al. 2005. Articular cartilage engineering with Hyalograft C: 3-year clinical results. Clin Orthop Relat Res (435):96-105.
23. Bora FW Jr, Miller G., 1987. Joint physiology, cartilage metabolism, and the etiology of osteoarthritis. Hand Clin 3:325-336.
24. Cagnard N, Letourneur F, Essabbani A, et al. 2005. Interleukin-32, CCL2, PF4F1 and GFD10 are the only cytokine/chemokine genes differentially expressed by in vitro cultured rheumatoid and osteoarthritis fibroblast-like synoviocytes. Eur Cytokine Netw 16:289-292.
25. Vergunst CE, van de Sande MG, Lebre MC, Tak PP., 2005. The role of chemokines in rheumatoid arthritis and osteoarthritis. Scand J Rheumatol 34:415-425.
26. Kraan MC, Patel DD, Haringman JJ, et al. 2001. The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8). Arthritis Res 3:65-71.
27. Ruschpler P, Lorenz P, Eichler W, et al. 2003. High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rheumatoid arthritis. Arthritis Res Ther 5:R241-R252.
28. Pierer M, Rethage J, Seibl R, et al. 2004. Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands. J Immunol 172:1256-1265.
29. Bramlage CP, Haupl T, Kaps C, et al. 2006. Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis. Arthritis Res Ther 8:R58.
30. Ertenli I, Kiraz S, Calguneri M, et al. 2001. Synovial fluid cytokine levels in Behcet's disease. Clin Exp Rheumatol 19(5 Suppl 24):S37-S41.
31. Sordi V, Malosio ML, Marchesi F, et al. 2005. Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood 106:419-427.
32. Wang L, Li Y, Chen X, et al. 2002. MCP-1, MIP-1, IL-8 and ischemic cerebral tissue enhance human bone marrow stromal cell migration in interface culture. Hematology 7:113-117.
33. Murphy JM, Dixon K, Beck S, et al. 2002. Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis. Arthritis Rheum 46:704-713.