Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors

Behavioural Brain Research

Volumn 216, Issue 1, 2011, Pages 477-480

  Higuchi, Sei ^a   Ohji, Makiko ^a   Araki, Maiko ^a   Furuta, Riyo ^a   Katsuki, Mai ^a   Yamaguchi, Ryuji ^a   Akitake, Yoshiharu ^a   Matsuyama, Kiyoshi ^a   Irie, Keiichi ^a   Mishima, Kenji ^a   Mishima, Kenichi ^a   Iwasaki, Katsunori ^a   Fujiwara, Michihiro ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

2 Arachidonoylglycerol; High fat diet; Hypothalamus; O 2050; Preference

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR ANTAGONIST; CHOLESTEROL; ENDOCANNABINOID; O 2050; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FOOD PREFERENCE; HYPOTHALAMUS; INSTITUTE FOR CANCER RESEARCH MOUSE; LIPID DIET; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL;

ANIMALS; ARACHIDONIC ACIDS; DIETARY FATS; EATING; FOOD PREFERENCES; GLYCERIDES; HYPOTHALAMUS; MALE; MICE; MICE, INBRED ICR; PYRANS; RECEPTOR, CANNABINOID, CB1; TETRAHYDROCANNABINOL;

EID: 78149411746     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2010.08.042     Document Type: Article

References (40)

1. Bellocchio L., Lafenêtre P., Cannich A., Cota D., Puente N., Grandes P. Bimodal control of stimulated food intake by the endocannabinoid system. Nat Neurosci 2010, 13:281-283.
2. Bisogno T., Burston J.J., Rai R., Allara M., Saha B., Mahadevan A. Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol. ChemMedChem 2009, 4:946-950.
3. Centonze D., Rossi S., De Chiara V., Prosperetti C., Battista N., Bernardi, et al. Chronic cocaine sensitizes striatal GABAergic synapses to the stimulation of cannabinoid CB1 receptors. Eur J Neurosci 2007, 25:1631-1640.
4. Cota D., Tschop M.H., Horvath T.L., Levine A.S. Cannabinoids opioids and eating behavior: the molecular face of hedonism?. Brain Res Rev 2006, 51:85-107.
5. Devane W.A., Dysarz F.A., Johnson M.R., Melvin L.S., Howlett A.C. Determination and characterization of a cannabinoid receptor in rat brain. Mol Pharmacol 1988, 34:605-613.
6. Di Marzo V., Ligresti A., Cristino L. The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation. Int J Obes 2009, 33:18-24.
7. Di Marzo V., Cote M., Matias I., Lemieux I., Arsenault B.J., Cartier A., et al. Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. Diabetologia 2009, 52:213-217.
8. Di Marzo V., Verrijken A., Hakkarainen A., Petrosino S., Mertens I., Lundbom N., et al. Role of the insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. Eur J Endocrinol 2009, 161:715-722.
9. Di Marzo V., Goparaju S.K., Wang L., Liu J., Batkai S., Jarai Z., et al. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 2001, 410:822-825.
10. Elizalde G., Sclafani A. Fat appetite in rats: flavor preferences conditioned by nutritive and non-nutritive oil emulsions. Appetite 1990, 15:189-197.
11. Fattore L., Spano M.S., Deiana S., Melis V., Cossu G., Fadda P., et al. An endocannabinoid mechanism in relapse to drug seeking: a review of animal studies and clinical perspectives. Brain Res Rev 2007, 53:1-16.
12. Herkenham M., Lynn A.B., Johnson M.R., Melvin L.S., Costa B.R., Rice K.C. Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study. J Neurosci 1991, 11:563-583.
13. Higuchi S., Irie K., Mishima S., Araki M., Ohji M., Shirakawa A., et al. The cannabinoid 1 receptor silent antagonist O-2050 attenuates preference for high-fat diet and activated astrocytes in mice. J Pharmacol Sci 2010, 112:369-372.
14. Higuera-Matas A., Luisa Soto-Montenegro M., Del Olmo N., Miguens M., Torres I., Jose Vaquero J., et al. Augmented acquisition of cocaine self-administration and altered brain glucose metabolism in adult female but not male rats exposed to a cannabinoid agonist during adolescence. Neuropsychopharmacology 2008, 33:806-813.
15. Imaizumi M., Takeda M., Fushiki T. Effect of oil intake in the conditioned place preference test in mice. Brain Res 2000, 870:150-156.
16. Kirkham T.C., Williams C.M., Fezza F., Di Marzo V. Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoylglycerol. Br J Pharmacol 2002, 136:550-557.
17. Ledent C., Valverde O., Cossu G., Petitet F., Aubert J.F., Beslot F., et al. Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 1999, 283:401-404.
18. 9-tetrahydrocannabinol: comparison with cocaine, morphine, and food reward. Life Sci 1995, 56:2073-2780.
19. Mechoulam R., Ben-Shabat S., Hanus L., Ligumsky M., Kaminski N.E., Schatz A.R., et al. Identification of endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 1995, 50:83-90.
20. Mela D.J., Sacchetti D.A. Sensory preferences for fats: relationships with diet and body composition. Am J Clin Nutr 1991, 53:908-915.
21. Mindell S., Smith G.P., Greenberg D. Corn oil and mineral oil stimulate sham feeding in rats. Physiol Behav 1990, 48:283-287.
22. Mizushige T., Kawai T., Matsumura S., Yoneda T., Kawada T., Tsuzuki S., et al. POMC and orexin mRNA expressions induced by anticipation of a corn-oil emulsion feeding are maintained at the high levels until oil ingestion. Biomed Res 2006, 27:227-232.
23. Mizushige T., Saitoh K., Manabe Y., Nishizuka T., Taka Y., Eguchi A. Preference for dietary fat induced by release of beta-endorphin in rats. Life Sci 2009, 84:760-765.
24. Pacher P., Batkai S., Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 2006, 58:389-462.
25. Perks S.M., Clifton P.G. Reinforce revaluation and conditioned place preference. Physiol Behav 1997, 61:1-5.
26. Quarta C., Bellocchio L., Mancini G., Mazza R., Cervin C., Luzie J., et al. CB1 signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance. Cell Metab 2010, 4:273-285.
27. Reed D.R., Tordoff M.G., Friedman M.I. Sham-feeding of corn oil by rats: sensory and postingestive factors. Physiol Behav 1990, 47:779-781.
28. Roefs A., Jansen A. Implicit and explicit attitudes toward high-fat foods in obesity. J Abnorm Psychol 2002, 111:517-521.
29. South T., Deng C., Huang X.F. AM 251 and beta-funaltrexamine reduce fat intake in a fat-preferring strain of mouse. Behav Brain Res 2007, 181:153-157.
30. Spyraki C., Fibiger H.C., Phillips A.G. Attenuation by haloperidol of place preference conditioning using food reinforcement. Psychopharmacology 1992, 18:75-83.
31. Stella N. Cannabinoid signaling in glial cells. Glia 2004, 48:267-277.
32. Sugiura T., Kondo S., Sukagawa A., Nakane S., Shinoda A., Itoh K., et al. 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. Biochem Biophys Res Commun 1995, 215:89-97.
33. Suzuki T. Conditioned place preference in mice. Methods Find Exp Clin Pharmacol 1982, 77:379-382.
34. Takeda M., Imaizumi M., Fushiki T. Preference for vegetable oils in the two-bottle choice test in mice. Life Sci 2000, 67:197-204.
35. Takeda M., Sawano S., Imaizumi M., Fushiki T. Preference for corn oil in olfactory-blocked mice in the conditioned place preference test and the two-bottle choice test. Life Sci 2001, 69:847-854.
36. Torelli G.F., Meguid M.M., Miyata G., Fetissov S.O., Carter J.L., Kim H.J. VMW hypothalamic dopamine and serotonin in anorectic septic rats. Shock 2000, 13:204-208.
37. Tsuruta M., Kawada T., Fukuwatari T., Fushiki T. The orosensory recording of long-chain fatty acids in rats. Physiol Behav 1999, 66:285-288.
38. Tzschentke T.M. Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues. Prog Neurobiol 1998, 56:613-672.
39. Verty A.N., McGregor I.S., Mallet P.E. Paraventricular hypothalamic CB(1) cannabinoid receptors are involved in the feeding stimulatory effects of delta(9)-tetrahydrocannabinol. Neuropharmacology 2005, 49:1101-1109.
40. Williams G., Bing C., Cai X.J., Harrold J.A., King P.J., Liu X.H. The hypothalamus and the control of energy homeostasis: different circuits and different purposes. Physiol Behav 2001, 74:683-701.