Cell-cell signaling in co-cultures of macrophages and fibroblasts

Biomaterials

Volumn 31, Issue 36, 2010, Pages 9382-9394

  Holt, Dolly J ^a   Chamberlain, Lisa M ^b,c   Grainger, David W ^a,b  

^a Department of Electrical and Computer Engineering   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Co culture; Cytokines; Fibroblast; Foreign body response; In vitro signaling; Macrophage

Indexed keywords

CELL CO-CULTURES; CELL CULTURE MEDIA; CELL IMAGES; CELL SIGNALING; CELL TYPES; CELL-CELL SIGNALING; CELLULAR BEHAVIORS; CO-CULTURES; COCULTURE; CONDITIONED MEDIAS; CYTOKINES; EFFECTOR CELLS; FOREIGN BODY RESPONSE; HOST TISSUES; IMPLANTED MATERIALS; IN-VITRO; IN-VIVO; INFLAMMATORY SIGNALING; JUXTACRINE SIGNALING; PARACRINE; PRIMARY CELLS; SECONDARY CELLS; SOLUBLE PROTEINS;

FIBROBLASTS; MACROPHAGES; SIGNALING; TISSUE;

CELL CULTURE;

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL COMMUNICATION AND CELL CONTACT; CELL FUNCTION; CELL STRUCTURE; CELL TYPE; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; EFFECTOR CELL; FEMALE; FIBROBLAST; FOREIGN BODY; IMAGING; IN VITRO STUDY; JUXTACRINE SIGNALING; MACROPHAGE; MALE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN SECRETION;

ANIMALS; BIOLOGICAL ASSAY; CELL ADHESION; CELL COMMUNICATION; CELL COUNT; CELL LINE; CELL PROLIFERATION; CELL SHAPE; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; CYTOKINES; FIBROBLASTS; INFLAMMATION MEDIATORS; KINETICS; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION;

EID: 78149409929     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.07.101     Document Type: Article

References (73)

1. Anderson J.M. Mechanisms of inflammation and infection with implanted devices. Cardiovasc Pathol 1993, 2:33S-41S. [Chapter 4].
2. Zhao Q., Topham N., Anderson J.M., Hiltner A., Lodoen G., Payet C.R. Foreign-body giant cells and polyurethane biostability: in vivo correlation of cell adhesion and surface cracking. J Biomed Mater Res 1991, 25:177-183.
3. Murray D.W., Rushton N. Macrophages stimulate bone resorption when they phagocytose particles. J Bone Jt Surg Br 1990, 72:988-992.
4. Chamberlain L.M., Godek M.L., Gonzalez-Juarrero M., Grainger D.W. Phenotypic non-equivalence of murine (monocyte-) macrophage cells in biomaterial and inflammatory models. J Biomed Mater Res A 2009, 88:858-871.
5. Luttikhuizen D.T., Harmsen M.C., Van Luyn M.J. Cellular and molecular dynamics in the foreign body reaction. Tissue Eng 2006, 12:1955-1970.
6. Schutte R.J., Parisi-Amon A., Reichert W.M. Cytokine profiling using monocytes/macrophages cultured on common biomaterials with a range of surface chemistries. J Biomed Mater Res A 2009, 88:128-139.
7. Ung D.Y., Woodhouse K.A., Sefton M.V. Tumor necrosis factor (TNFalpha) production by rat peritoneal macrophages is not polyacrylate surface-chemistry dependent. J Biomed Mater Res 1999, 46:324-330.
8. Scheibenbogen C., Andreesen R. Developmental regulation of the cytokine repertoire in human macrophages: IL-1, IL-6, TNF-alpha, and M-CSF. J Leukoc Biol 1991, 50:35-42.
9. Whelan R.D., Kiley S.C., Parker P.J. Tetradecanoyl phorbol acetate-induced microtubule reorganization is required for sustained mitogen-activated protein kinase activation and morphological differentiation of U937 cells. Cell Growth Differ 1999, 10:271-277.
10. Gretzer C., Emanuelsson L., Liljensten E., Thomsen P. The inflammatory cell influx and cytokines changes during transition from acute inflammation to fibrous repair around implanted materials. J Biomater Sci Polym Ed 2006, 17:669-687.
11. Schutte R.J., Xie L., Klitzman B., Reichert W.M. In vivo cytokine-associated responses to biomaterials. Biomaterials 2009, 30:160-168.
12. Roumestan C., Michel A., Bichon F., Portet K., Detoc M., Henriquet C., et al. Anti-inflammatory properties of desipramine and fluoxetine. Respir Res 2007, 8:35.
13. Hayflick L., Moorhead P.S. The serial cultivation of human diploid cell strains. Exp Cell Res 1961, 25:585-621.
14. Hughes P., Marshall D., Reid Y., Parkes H., Gelber C. The costs of using unauthenticated, over-passaged cell lines: how much more data do we need?. Biotechniques 2007, 43(575):7-8. 81-2 passim.
15. Sandeep Varma R., Ashok G., Vidyashankar S., Patki P., Nandakumar K.S. Anti-inflammatory properties of septilin in lipopolysaccharide activated monocytes and macrophage. Immunopharmacol Immunotoxicol 2010, 10.3109/08923971003739236.
16. Lin N.J., Hu H., Sung L., Lin-Gibson S. Quantification of cell response to polymeric composites using a two-dimensional gradient platform. Comb Chem High Throughput Screen 2009, 12:619-625.
17. Yoon W.J., Ham Y.M., Yoo B.S., Moon J.Y., Koh J., Hyun C.G. Oenothera laciniata inhibits lipopolysaccharide induced production of nitric oxide, prostaglandin E2, and proinflammatory cytokines in RAW264.7 macrophages. J Biosci Bioeng 2009, 107:429-438.
18. Kelly M., Kolb M., Bonniaud P., Gauldie J. Re-evaluation of fibrogenic cytokines in lung fibrosis. Curr Pharm Des 2003, 9:39-49.
19. Liu X., Li J., Zhang J. STAT3-decoy ODN inhibits cytokine autocrine of murine tumor cells. Cell Mol Immunol 2007, 4:309-313.
20. Anderson J.M., Rodriguez A., Chang D.T. Foreign body reaction to biomaterials. Semin Immunol 2008, 20:86-100.
21. Ask K., Bonniaud P., Maass K., Eickelberg O., Margetts P.J., Warburton D., et al. Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3. Int J Biochem Cell Biol 2008, 40:484-495.
22. Higgins D.M., Basaraba R.J., Hohnbaum A.C., Lee E.J., Grainger D.W., Gonzalez-Juarrero M. Localized immunosuppressive environment in the foreign body response to implanted biomaterials. Am J Pathol 2009, 175:161-170.
23. Godek M.L., Sampson J.A., Duchsherer N.L., McElwee Q., Grainger D.W. Rho GTPase protein expression and activation in murine monocytes/macrophages is not modulated by model biomaterial surfaces in serum-containing in vitro cultures. J Biomater Sci Polym Ed 2006, 17:1141-1158.
24. Rhoades E.R., Orme I.M. Similar responses by macrophages from young and old mice infected with Mycobacterium tuberculosis. Mech Ageing Dev 1998, 106:145-153.
25. Morgan E., Varro R., Sepulveda H., Ember J.A., Apgar J., Wilson J., et al. Cytometric bead array: a multiplexed assay platform with applications in various areas of biology. Clin Immunol 2004, 110:252-266.
26. Dunnett C., Goldsmith C. When and how to do multiple comparisons. Statistics in the pharmaceutical industry 2006, 421-452. Chapman and Hall/CRC, New York. 3rd ed. C.R. Buncher, J.-Y. Tsay (Eds.).
27. Godek M.L., Michel R., Chamberlain L.M., Castner D.G., Grainger D.W. Adsorbed serum albumin is permissive to macrophage attachment to perfluorocarbon polymer surfaces in culture. J Biomed Mater Res A 2009, 88:503-519.
28. Godek M.L., Duchsherer N.L., McElwee Q., Grainger D.W. Morphology and growth of murine cell lines on model biomaterials. Biomed Sci Instrum 2004, 40:7-12.
29. Takahashi H., Emoto K., Dubey M.G., Castner D.G., Grainger D.W. Imaging surface immobilization chemistry: correlation with cell patterning on non-adhesive hydrogel thin films. Adv Funct Mater 2008, 18:1-10.
30. Kim D.H., Smith J.T., Chilkoti A., Reichert W.M. The effect of covalently immobilized rhIL-1ra-ELP fusion protein on the inflammatory profile of LPS-stimulated human monocytes. Biomaterials 2007, 28:3369-3377.
31. Gordon S., Taylor P.R. Monocyte and macrophage heterogeneity. Nat Rev Immunol 2005, 5:953-964.
32. Volin M.V., Shah M.R., Tokuhira M., Haines G.K., Woods J.M., Koch A.E. RANTES expression and contribution to monocyte chemotaxis in arthritis. Clin Immunol Immunopathol 1998, 89:44-53.
33. Nath A., Chattopadhya S., Chattopadhyay U., Sharma N.K. Macrophage inflammatory protein (MIP)1alpha and MIP1beta differentially regulate release of inflammatory cytokines and generation of tumoricidal monocytes in malignancy. Cancer Immunol Immunother 2006, 55:1534-1541.
34. Isumi Y., Minamino N., Kubo A., Nishimoto N., Yoshizaki K., Yoshioka M., et al. Adrenomedullin stimulates interleukin-6 production in Swiss 3T3 cells. Biochem Biophys Res Commun 1998, 244:325-331.
35. Helfgott D.C., May L.T., Sthoeger Z., Tamm I., Sehgal P.B. Bacterial lipopolysaccharide (endotoxin) enhances expression and secretion of beta 2 interferon by human fibroblasts. J Exp Med 1987, 166:1300-1309.
36. Kitamura H., Kanehira K., Okita K., Morimatsu M., Saito M. MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production. FEBS Lett 2000, 485:53-56.
37. Brown D.M., Wilson M.R., MacNee W., Stone V., Donaldson K. Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines. Toxicol Appl Pharmacol 2001, 175:191-199.
38. Ratner B.D. Reducing capsular thickness and enhancing angiogenesis around implant drug release systems. J Control Release 2002, 78:211-218.
39. Draisma A., de Goeij M., Wouters C.W., Riksen N.P., Oyen W.J., Rongen G.A., et al. Endotoxin tolerance does not limit mild ischemia-reperfusion injury in humans in vivo. Innate Immun 2009, 15:360-367.
40. Porta C., Rimoldi M., Raes G., Brys L., Ghezzi P., Di Liberto D., et al. Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A 2009, 106:14978-14983.
41. Ziegler-Heitbrock H.W. Molecular mechanism in tolerance to lipopolysaccharide. J Inflamm 1995, 45:13-26.
42. Sly L.M., Rauh M.J., Kalesnikoff J., Song C.H., Krystal G. LPS-induced upregulation of SHIP is essential for endotoxin tolerance. Immunity 2004, 21:227-239.
43. Zhu M.F., Zhang J., Qu J.M., Zhang H.J., Zhou S.C., Dong S.F., et al. Up-regulation of growth factor independence 1 in endotoxin tolerant macrophages with low secretion of TNF-alpha and IL-6. Inflamm Res 2010, 10.1007/s00011-010-0197-1.
44. West M.A., Hackam D.J., Baker J., Rodriguez J.L., Bellingham J., Rotstein O.D. Mechanism of decreased in vitro murine macrophage cytokine release after exposure to carbon dioxide: relevance to laparoscopic surgery. Ann Surg 1997, 226:179-190.
45. Jakobsen S.S., Larsen A., Stoltenberg M., Bruun J.M., Soballe K. Effects of as-cast and wrought cobalt-chrome-molybdenum and titanium-aluminium-vanadium alloys on cytokine gene expression and protein secretion in J774A.1 macrophages. Eur Cell Mater 2007, 14:45-54. discussion -5.
46. Vittimberga F.J., Foley D.P., Perugini R.A., McDade T.P., Callery M.P. Endotoxin fails to stimulate inositol triphosphate production in macrophages. Int J Surg Investig 1999, 1:229-235.
47. Wang X., Lennartz M.R., Loegering D.J., Stenken J.A. Interleukin-6 collection through long-term implanted microdialysis sampling probes in rat subcutaneous space. Anal Chem 2007, 79:1816-1824.
48. Oshikawa K., Yamasawa H., Sugiyama Y. Human lung fibroblasts inhibit macrophage inflammatory protein-1alpha production by lipopolysaccharide-stimulated macrophages. Biochem Biophys Res Commun 2003, 312:650-655.
49. Vancheri C., Crimi N., Conte E., Pistorio M.P., Mastruzzo C., Lamicela M., et al. Human lung fibroblasts inhibit tumor necrosis factor-alpha production by LPS-activated monocytes. Am J Respir Cell Mol Biol 1996, 15:460-466.
50. Gosling J., Slaymaker S., Gu L., Tseng S., Zlot C.H., Young S.G., et al. MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. J Clin Invest 1999, 103:773-778.
51. Satriano J.A., Hora K., Shan Z., Stanley E.R., Mori T., Schlondorff D. Regulation of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor-1 by IFN-gamma, tumor necrosis factor-alpha, IgG aggregates, and cAMP in mouse mesangial cells. J Immunol 1993, 150:1971-1978.
52. Kumar S.N., Boss J.M. Site A of the MCP-1 distal regulatory region functions as a transcriptional modulator through the transcription factor NF1. Mol Immunol 2000, 37:623-632.
53. Palombella V.J., Mendelsohn J., Vilcek J. Mitogenic action of tumor necrosis factor in human fibroblasts: interaction with epidermal growth factor and platelet-derived growth factor. J Cell Physiol 1988, 135:23-31.
54. Vancheri C., Sortino M.A., Tomaselli V., Mastruzzo C., Condorelli F., Bellistri G., et al. Different expression of TNF-alpha receptors and prostaglandin E2 production in normal and fibrotic lung fibroblasts: potential implications for the evolution of the inflammatory process. Am J Respir Cell Mol Biol 2000, 22:628-634.
55. Sun L.K., Reding T., Bain M., Heikenwalder M., Bimmler D., Graf R. Prostaglandin E2 modulates TNF-alpha-induced MCP-1 synthesis in pancreatic acinar cells in a PKA-dependent manner. Am J Physiol Gastrointest Liver Physiol 2007, 293:G1196-G1204.
56. Goldstein R.H., Polgar P. The effect and interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts. J Biol Chem 1982, 257:8630-8633.
57. Rosenquist J.B., Ohlin A., Lerner U.H. Cytokine-induced inhibition of bone matrix proteins is not mediated by prostaglandins. Inflamm Res 1996, 45:457-463.
58. Helming L., Gordon S. Macrophage fusion induced by IL-4 alternative activation is a multistage process involving multiple target molecules. Eur J Immunol 2007, 37:33-42.
59. MacLauchlan S., Skokos E.A., Meznarich N., Zhu D.H., Raoof S., Shipley J.M., et al. Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9. J Leukoc Biol 2009, 85:617-626.
60. Wang Y, Grainger DW. siRNA knock-down of RANK signaling to control osteoclast-mediated bone resorption. Pharm Res 27:1273-1284.
61. Xiao X.H., Liao E.Y., Zhou H.D., Dai R.C., Yuan L.Q., Wu X.P. Ascorbic acid inhibits osteoclastogenesis of RAW264.7 cells induced by receptor activated nuclear factor kappaB ligand (RANKL) in vitro. J Endocrinol Invest 2005, 28:253-260.
62. Jay S.M., Skokos E., Laiwalla F., Krady M.M., Kyriakides T.R. Foreign body giant cell formation is preceded by lamellipodia formation and can be attenuated by inhibition of Rac1 activation. Am J Pathol 2007, 171:632-640.
63. Godek M.L., Malkov G.S., Fisher E.R., Grainger D.W. Macrophage serum-based adhesion to plasma-processed surface chemistry is distinct from that exhibited by fibroblasts. Plasma Process Polym 2006, 3:485-497.
64. Ghezzi P., Sacco S., Agnello D., Marullo A., Caselli G., Bertini R. LPS induces IL-6 in the brain and in serum largely through TNF production. Cytokines 2000, 12:1205-1210.
65. Smith R.E., Strieter R.M., Phan S.H., Lukacs N., Kunkel S.L. TNF and IL-6 mediate MIP-1alpha expression in bleomycin-induced lung injury. J Leukoc Biol 1998, 64:528-536.
66. Fahey T.J., Tracey K.J., Tekamp-Olson P., Cousens L.S., Jones W.G., Shires G.T., et al. Macrophage inflammatory protein 1 modulates macrophage function. J Immunol 1992, 148:2764-2769.
67. Santavirta S., Konttinen Y.T., Bergroth V., Eskola A., Tallroth K., Lindholm T.S. Aggressive granulomatous lesions associated with hip arthroplasty. Immunopathological studies. J Bone Jt Surg Am 1990, 72:252-258.
68. Jiranek W.A., Machado M., Jasty M., Jevsevar D., Wolfe H.J., Goldring S.R., et al. Production of cytokines around loosened cemented acetabular components. Analysis with immunohistochemical techniques and in situ hybridization. J Bone Jt Surg Am 1993, 75:863-879.
69. Neale S.D., Sabokbar A., Howie D.W., Murray D.W., Athanasou N.A. Macrophage colony-stimulating factor and interleukin-6 release by periprosthetic cells stimulates osteoclast formation and bone resorption. J Orthop Res 1999, 17:686-694.
70. Al-Saffar N., Revell P.A. Differential expression of transforming growth factor-alpha and macrophage colony-stimulating factor/colony-stimulating factor-1R (c-fins) by multinucleated giant cells involved in pathological bone resorption at the site of orthopaedic implants. J Orthop Res 2000, 18:800-807.
71. Shahrara S., Park C.C., Temkin V., Jarvis J.W., Volin M.V., Pope R.M. RANTES modulates TLR4-induced cytokine secretion in human peripheral blood monocytes. J Immunol 2006, 177:5077-5087.
72. Starkie R., Ostrowski S.R., Jauffred S., Febbraio M., Pedersen B.K. Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans. FASEB J 2003, 17:884-886.
73. Elias J.A., Rossman M.D., Zurier R.B., Daniele R.P. Human alveolar macrophage inhibition of lung fibroblast growth. A prostaglandin-dependent process. Am Rev Respir Dis 1985, 131:94-99.