-
1
-
-
0033168459
-
Shattuck lecture-medical and societal consequences of the Human Genome Project
-
Collins FS (1999) Shattuck lecture-medical and societal consequences of the Human Genome Project. N Engl J Med 341: 28-37.
-
(1999)
N Engl J Med
, vol.341
, pp. 28-37
-
-
Collins, F.S.1
-
2
-
-
0002391321
-
The human genome project and the future of diagnostics, treatment, and prevention
-
van Ommen GJ, Bakker E, den Dunnen JT (1999) The human genome project and the future of diagnostics, treatment, and prevention. Lancet 354 Suppl 1: SI5-10.
-
(1999)
Lancet
, vol.354
, Issue.1
-
-
van Ommen, G.J.1
Bakker, E.2
den Dunnen, J.T.3
-
3
-
-
57649136554
-
Progress and challenges in genome-wide association studies in humans
-
Donnelly P (2008) Progress and challenges in genome-wide association studies in humans. Nature 456: 728-31.
-
(2008)
Nature
, vol.456
, pp. 728-731
-
-
Donnelly, P.1
-
4
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U SA 106: 9362-7.
-
(2009)
Proc Natl Acad Sci U SA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
-
5
-
-
43049146524
-
A HapMap harvest of insights into the genetics of common disease
-
Manolio TA, Brooks LD, Collins FS (2008) A HapMap harvest of insights into the genetics of common disease. J Clin Invest 118: 1590-605.
-
(2008)
J Clin Invest
, vol.118
, pp. 1590-1605
-
-
Manolio, T.A.1
Brooks, L.D.2
Collins, F.S.3
-
6
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, et al. (2009) Finding the missing heritability of complex diseases. Nature 461: 747-53.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
-
7
-
-
74049131900
-
Genetic risk information for common diseases may indeed be already useful for prevention and early detection
-
Gulcher J, Stefansson K (2010) Genetic risk information for common diseases may indeed be already useful for prevention and early detection. Eur J Clin Invest 40: 56-63.
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 56-63
-
-
Gulcher, J.1
Stefansson, K.2
-
8
-
-
0042978831
-
Genetics and genomics in practice: The continuum from genetic disease to genetic information in health and disease
-
Khoury MJ (2003) Genetics and genomics in practice: the continuum from genetic disease to genetic information in health and disease. Genet Med 5: 261-268.
-
(2003)
Genet Med
, vol.5
, pp. 261-268
-
-
Khoury, M.J.1
-
9
-
-
0842305961
-
An epidemiological assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions
-
Khoury MJ, Yang Q, Gwinn M, Little J, Flanders WD (2004) An epidemiological assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions. Genet Med 6: 38-47.
-
(2004)
Genet Med
, vol.6
, pp. 38-47
-
-
Khoury, M.J.1
Yang, Q.2
Gwinn, M.3
Little, J.4
Flanders, W.D.5
-
10
-
-
65949099120
-
Genetic risk prediction-are we there yet?
-
Kraft P, Hunter DJ (2009) Genetic risk prediction-are we there yet? N Engl J Med 360: 1701-3.
-
(2009)
N Engl J Med
, vol.360
, pp. 1701-1703
-
-
Kraft, P.1
Hunter, D.J.2
-
11
-
-
0036578764
-
Polygenic susceptibility to breast cancer and implications for prevention
-
Pharoah PD, Antoniou A, Bobrow M, Zimmern RL, Easton DF, et al. (2002) Polygenic susceptibility to breast cancer and implications for prevention. Nat Genet 31: 33-6.
-
(2002)
Nat Genet
, vol.31
, pp. 33-36
-
-
Pharoah, P.D.1
Antoniou, A.2
Bobrow, M.3
Zimmern, R.L.4
Easton, D.F.5
-
12
-
-
42649123990
-
Sizing up human height variation
-
Visscher PM (2008) Sizing up human height variation. Nat Genet 40: 489-490.
-
(2008)
Nat Genet
, vol.40
, pp. 489-490
-
-
Visscher, P.M.1
-
13
-
-
68249108329
-
Prediction and interaction in complex disease genetics: Experience in type 1 diabetes
-
doi:10.1371/journal.pgen.1000540
-
Clayton DG (2009) Prediction and interaction in complex disease genetics: experience in type 1 diabetes. PLoS Genet 5: e1000540. doi:10.1371/ journal.pgen.1000540.
-
(2009)
PLoS Genet
, vol.5
-
-
Clayton, D.G.1
-
14
-
-
33747881836
-
Predictive testing for complex diseases using multiple genes: Fact or fiction?
-
Janssens AC, Aulchenko YS, Elefante S, Borsboom GJ, Steyerberg EW, et al. (2006) Predictive testing for complex diseases using multiple genes: fact or fiction? Genet Med 8: 395-400.
-
(2006)
Genet Med
, vol.8
, pp. 395-400
-
-
Janssens, A.C.1
Aulchenko, Y.S.2
Elefante, S.3
Borsboom, G.J.4
Steyerberg, E.W.5
-
15
-
-
34948877698
-
Prediction of individual genetic risk to disease from genome-wide association studies
-
Wray NR, Goddard ME, Visscher PM (2007) Prediction of individual genetic risk to disease from genome-wide association studies. Genome Res 17: 1520-8.
-
(2007)
Genome Res
, vol.17
, pp. 1520-1528
-
-
Wray, N.R.1
Goddard, M.E.2
Visscher, P.M.3
-
16
-
-
77649209124
-
The genetic interpretation of area under the ROC curve in genomic profiling
-
doi:10.1371/journal.pgen.1000864
-
Wray NR, Yang J, Goddard ME, Visscher PM (2010) The genetic interpretation of area under the ROC curve in genomic profiling. PLoS Genet. 6:e1000864. doi:10.1371/journal. pgen.1000864.
-
(2010)
PLoS Genet
, vol.6
-
-
Wray, N.R.1
Yang, J.2
Goddard, M.E.3
Visscher, P.M.4
-
17
-
-
68949191441
-
Genome-based prediction of common diseases: Methodological considerations for future research
-
Janssens AC, van Duijn CM (2009) Genome-based prediction of common diseases: methodological considerations for future research. Genome Med 1: 20.
-
(2009)
Genome Med
, vol.1
, pp. 20
-
-
Janssens, A.C.1
van Duijn, C.M.2
-
18
-
-
56349096931
-
Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk
-
Lango H, Palmer CN, Morris AD, Zeggini E, Hattersley AT, et al. (2008) Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. Diabetes 57: 3129-35.
-
(2008)
Diabetes
, vol.57
, pp. 3129-3135
-
-
Lango, H.1
Palmer, C.N.2
Morris, A.D.3
Zeggini, E.4
Hattersley, A.T.5
-
19
-
-
40949149395
-
Polymorphisms associated with cholesterol and risk of cardiovascular events
-
Kathiresan S, Melander O, Anevski D, Guiducci C, Burtt NP, et al. (2008) Polymorphisms associated with cholesterol and risk of cardiovascular events. N Engl J Med 358: 1240-1249.
-
(2008)
N Engl J Med
, vol.358
, pp. 1240-1249
-
-
Kathiresan, S.1
Melander, O.2
Anevski, D.3
Guiducci, C.4
Burtt, N.P.5
-
21
-
-
45949085378
-
Polygenes, risk prediction, and targeted prevention of breast cancer
-
Pharoah PD, Antoniou AC, Easton DF, Ponder BA (2008) Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med 358: 2796-803.
-
(2008)
N Engl J Med
, vol.358
, pp. 2796-2803
-
-
Pharoah, P.D.1
Antoniou, A.C.2
Easton, D.F.3
Ponder, B.A.4
-
22
-
-
40849097776
-
Heritability in the genomics era-concepts and misconceptions
-
Visscher PM, Hill WG, Wray NR (2008) Heritability in the genomics era-concepts and misconceptions. Nat Rev Genet 9: 255-66.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 255-266
-
-
Visscher, P.M.1
Hill, W.G.2
Wray, N.R.3
-
23
-
-
0035962372
-
The complexities of predictive genetic testing
-
Evans JP, Skrzynia C, Burke W (2001) The complexities of predictive genetic testing. BMJ 322: 1052-6.
-
(2001)
BMJ
, vol.322
, pp. 1052-1056
-
-
Evans, J.P.1
Skrzynia, C.2
Burke, W.3
-
24
-
-
0037413486
-
Population screening in the age of genomic medicine
-
Khoury MJ, McCabe LL, McCabe ER (2003) Population screening in the age of genomic medicine. N Engl J Med 348: 50-8.
-
(2003)
N Engl J Med
, vol.348
, pp. 50-58
-
-
Khoury, M.J.1
McCabe, L.L.2
McCabe, E.R.3
-
26
-
-
0042166204
-
Genomic profiling to promote a healthy lifestyle: Not ready for prime time
-
Haga SB, Khoury MJ, Burke W (2003) Genomic profiling to promote a healthy lifestyle: not ready for prime time. Nat Genet 34: 347-50.
-
(2003)
Nat Genet
, vol.34
, pp. 347-350
-
-
Haga, S.B.1
Khoury, M.J.2
Burke, W.3
-
27
-
-
74049101159
-
Personal genomics: Information can be harmful
-
Ransohoff DF, Khoury MJ (2010) Personal genomics: information can be harmful. Eur J Clin Invest 40: 64-8.
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 64-68
-
-
Ransohoff, D.F.1
Khoury, M.J.2
-
28
-
-
75449105857
-
Blood and tissue biomarkers in prostate cancer: State of the art
-
Fiorentino M, Capizzi E, Loda M (2010) Blood and tissue biomarkers in prostate cancer: state of the art. Urol Clin North Am 37: 131-41.
-
(2010)
Urol Clin North Am
, vol.37
, pp. 131-141
-
-
Fiorentino, M.1
Capizzi, E.2
Loda, M.3
-
29
-
-
70349579099
-
Screening for prostate cancer: Explaining new trial results and their implications to patients
-
Barratt AL, Stockler MR (2009) Screening for prostate cancer: explaining new trial results and their implications to patients. Med J Aust 191: 226-9.
-
(2009)
Med J Aust
, vol.191
, pp. 226-229
-
-
Barratt, A.L.1
Stockler, M.R.2
-
30
-
-
38049130261
-
Letting the genome out of the bottle-will we get our wish?
-
Hunter DJ, Khoury MJ, Drazen JM (2008) Letting the genome out of the bottle-will we get our wish? N Engl J Med 358: 105-7.
-
(2008)
N Engl J Med
, vol.358
, pp. 105-107
-
-
Hunter, D.J.1
Khoury, M.J.2
Drazen, J.M.3
-
31
-
-
0035902067
-
Cancer epidemiology in the last century and the next decade
-
390-295
-
Peto J (2001) Cancer epidemiology in the last century and the next decade. Nature 411: 390-295.
-
(2001)
Nature
, vol.411
-
-
Peto, J.1
-
32
-
-
67650925282
-
Disclosure of APOE genotype for risk of Alzheimer's disease
-
Green RC, Roberts JS, Cupples LA, Relkin NR, Whitehouse PJ, et al. (2009) Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med 361: 245-54.
-
(2009)
N Engl J Med
, vol.361
, pp. 245-254
-
-
Green, R.C.1
Roberts, J.S.2
Cupples, L.A.3
Relkin, N.R.4
Whitehouse, P.J.5
-
33
-
-
65849113644
-
Impact of genetic risk information and type of disease on perceived risk, anticipated affect, and expected consequences of genetic tests
-
Cameron LD, Sherman KA, Marteau TM, Brown PM (2009) Impact of genetic risk information and type of disease on perceived risk, anticipated affect, and expected consequences of genetic tests. Health Psychol 28: 307-16.
-
(2009)
Health Psychol
, vol.28
, pp. 307-316
-
-
Cameron, L.D.1
Sherman, K.A.2
Marteau, T.M.3
Brown, P.M.4
-
34
-
-
77950832782
-
Future health applications of genomics: Priorities for communication, behavioral, and social sciences research
-
McBride CM, Bowen D, Brody LC, Condit CM, Croyle RT, et al. (2010) Future health applications of genomics: priorities for communication, behavioral, and social sciences research. Am J Prev Med 38: 556-65.
-
(2010)
Am J Prev Med
, vol.38
, pp. 556-565
-
-
McBride, C.M.1
Bowen, D.2
Brody, L.C.3
Condit, C.M.4
Croyle, R.T.5
-
35
-
-
0344338425
-
Impact of genetic testing on causal models of heart disease and arthritis: An analogue study
-
Senior V, Marteau TM, Weinman J (2000) Impact of genetic testing on causal models of heart disease and arthritis: an analogue study. Psychol Health 14: 1077-1088.
-
(2000)
Psychol Health
, vol.14
, pp. 1077-1088
-
-
Senior, V.1
Marteau, T.M.2
Weinman, J.3
-
36
-
-
0142194257
-
The impact of learning of a genetic predisposition to nicotine dependence: An analogue study
-
Wright AJ, Weinman J, Marteau TM (2003) The impact of learning of a genetic predisposition to nicotine dependence: an analogue study. Tob Control 12: 227-30.
-
(2003)
Tob Control
, vol.12
, pp. 227-230
-
-
Wright, A.J.1
Weinman, J.2
Marteau, T.M.3
-
37
-
-
32144459993
-
Self-regulation and the behavioural response to DNA risk information: A theoretical analysis and framework for future research
-
Marteau TM, Weinman J (2006) Self-regulation and the behavioural response to DNA risk information: a theoretical analysis and framework for future research. Soc Sci Med 62: 1360-1368.
-
(2006)
Soc Sci Med
, vol.62
, pp. 1360-1368
-
-
Marteau, T.M.1
Weinman, J.2
-
38
-
-
77649168190
-
The global research neglect of unassisted smoking cessation: Causes and consequences
-
doi:10.1371/journal.pmed.1000216
-
Chapman S, MacKenzie R (2010) The global research neglect of unassisted smoking cessation: causes and consequences. PLoS Med 7: e1000216. doi:10.1371/journal.pmed.1000216.
-
(2010)
PLoS Med
, vol.7
-
-
Chapman, S.1
Mackenzie, R.2
-
39
-
-
0036280883
-
Incorporating genetic susceptibility feedback into a smoking cessation program for African-American smokers with low income
-
McBride CM, Bepler G, Lipkus IM, Lyna P, Samsa G, et al. (2002) Incorporating genetic susceptibility feedback into a smoking cessation program for African-American smokers with low income. Cancer Epidemiol Biomarkers Prev 11: 521-528.
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 521-528
-
-
McBride, C.M.1
Bepler, G.2
Lipkus, I.M.3
Lyna, P.4
Samsa, G.5
-
40
-
-
42149190644
-
Psychological and behavioural impact of genetic testing smokers for lung cancer risk: A phase II exploratory trial
-
Sanderson SC, Humphries SE, Hubbart C (2008) Psychological and behavioural impact of genetic testing smokers for lung cancer risk: a phase II exploratory trial. J Health Psychol 13: 481-494.
-
(2008)
J Health Psychol
, vol.13
, pp. 481-494
-
-
Sanderson, S.C.1
Humphries, S.E.2
Hubbart, C.3
-
41
-
-
10844222436
-
Psychosocial impact of breast/ ovarian (BRCA1/2) cancer-predictive genetic testing in a UK multi-centre clinical cohort
-
Watson M, Foster C, Eeles R, Eccles D, Ashley S, et al. (2004) Psychosocial impact of breast/ ovarian (BRCA1/2) cancer-predictive genetic testing in a UK multi-centre clinical cohort. Br J Cancer 91: 1787-1794.
-
(2004)
Br J Cancer
, vol.91
, pp. 1787-1794
-
-
Watson, M.1
Foster, C.2
Eeles, R.3
Eccles, D.4
Ashley, S.5
-
42
-
-
1842450372
-
How has the prevalence of cigarette smoking changed among Australian adults? Trends in smoking prevalence between 1980 and 2001
-
White V, Hill D, Siahpush M, Bobevski I, (2003) How has the prevalence of cigarette smoking changed among Australian adults? Trends in smoking prevalence between 1980 and 2001. Tob Control 12 (Suppl 2_: ii67-74.
-
(2003)
Tob Control
, vol.12
, Issue.2
-
-
White, V.1
Hill, D.2
Siahpush, M.3
Bobevski, I.4
-
43
-
-
0032500290
-
Has the California tobacco control program reduced smoking?
-
Pierce JP, Gilpin EA, Emery SL, White MM, Rosbrook B, et al. (1998) Has the California tobacco control program reduced smoking? JAMA 280: 893-899.
-
(1998)
JAMA
, vol.280
, pp. 893-899
-
-
Pierce, J.P.1
Gilpin, E.A.2
Emery, S.L.3
White, M.M.4
Rosbrook, B.5
-
44
-
-
0036615695
-
The genetics of tobacco use: Methods, findings and policy implications
-
Hall WD, Madden P, Lynskey M (2002) The genetics of tobacco use: methods, findings and policy implications. Tob Control 11: 119-124.
-
(2002)
Tob Control
, vol.11
, pp. 119-124
-
-
Hall, W.D.1
Madden, P.2
Lynskey, M.3
-
45
-
-
76249094623
-
Beyond tax: The need for research on alcohol pricing policies
-
Chaloupka FJ (2010) Beyond tax: the need for research on alcohol pricing policies. Addiction 105: 397-8.
-
(2010)
Addiction
, vol.105
, pp. 397-398
-
-
Chaloupka, F.J.1
-
47
-
-
38849204738
-
The genetics of nicotine addiction liability: Ethical and social policy implications
-
Hall WD, Gartner CE, Carter A (2008) The genetics of nicotine addiction liability: ethical and social policy implications. Addiction 103: 350-359.
-
(2008)
Addiction
, vol.103
, pp. 350-359
-
-
Hall, W.D.1
Gartner, C.E.2
Carter, A.3
-
48
-
-
77951982812
-
'To prove this is the industry's best hope': Big tobacco's support of research on the genetics of nicotine addiction
-
Gundle KR, Dingel MJ, Koenig BA, (2010) 'To prove this is the industry's best hope': big tobacco's support of research on the genetics of nicotine addiction. Addiction 105: 974-983.
-
(2010)
Addiction
, vol.105
, pp. 974-983
-
-
Gundle, K.R.1
Dingel, M.J.2
Koenig, B.A.3
-
49
-
-
24644497616
-
British drinking: A suitable case for treatment?
-
Hall WD (2005) British drinking: a suitable case for treatment? BMJ 331: 527-528.
-
(2005)
BMJ
, vol.331
, pp. 527-528
-
-
Hall, W.D.1
-
50
-
-
72249121875
-
Vested interests, addiction research and public policy
-
Babor T, Miller P, Edwards G (2010) Vested interests, addiction research and public policy. Addiction 105: 4-5.
-
(2010)
Addiction
, vol.105
, pp. 4-5
-
-
Babor, T.1
Miller, P.2
Edwards, G.3
-
51
-
-
38349118851
-
Capital ventures into biology: Biosocial dynamics in the industry and science of gambling
-
Vrecko S (2008) Capital ventures into biology: biosocial dynamics in the industry and science of gambling. Econ Soc 37: 50-67.
-
(2008)
Econ Soc
, vol.37
, pp. 50-67
-
-
Vrecko, S.1
-
52
-
-
26944437969
-
Genetic epidemiology and public health: Hope, hype, and future prospects
-
Davey Smith G, Ebrahim S, Lewis S, Hansell AL, Palmer LJ, et al. (2005) Genetic epidemiology and public health: hope, hype, and future prospects. Lancet 366: 1484-98.
-
(2005)
Lancet
, vol.366
, pp. 1484-1498
-
-
Smith, G.D.1
Ebrahim, S.2
Lewis, S.3
Hansell, A.L.4
Palmer, L.J.5
|