Focal positive surgical margins decrease disease-free survival after radical prostatectomy even in organ-confined disease

Urology

Volumn 76, Issue 5, 2010, Pages 1212-1216

  Lake, Alison M ^a   He, Chang ^a   Wood Jr , David P ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; ARTICLE; CANCER STAGING; CANCER SURVIVAL; DISEASE FREE SURVIVAL; FOCAL POSITIVE MARGIN; FOLLOW UP; GLEASON SCORE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATECTOMY; RECURRENCE RISK; RETROSPECTIVE STUDY;

DISEASE-FREE SURVIVAL; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; PROSTATE; PROSTATECTOMY; PROSTATIC NEOPLASMS; SALVAGE THERAPY;

EID: 78149360689     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2009.08.088     Document Type: Article

References (11)

1. M.W. Kattan, T.M. Wheeler, and P.T. Scardino Postoperative nomogram for disease recurrence after radical prostatectomy for prostate cancer J Clin Oncol 17 1999 1499 1507
2. G.W. Hull, F. Tabbani, and F. Abbas Cancer control with radical prostatectomy alone in 1000 consecutive patients J Urol 167 2002 528 534
3. G.D. Grossfield, J.J. Chang, and H.M. Broering Impact of positive surgical margins on prostate cancer recurrence and the use of secondary cancer treatment: data from the CaPSURE database J Urol 163 2000 1171 1177
4. I.M. Thompson, C.M. Tange, and J. Paradelo Adjuvant radiotherapy for pathological T3N0M0 prostate cancer significantly reduces risk of metastases and improves survival: long-term followup of a randomized clinical trial J Urol 181 2009 956 962
5. M.A. Simon, S. Kim, and M.S. Soloway Prostate specific antigen recurrence rates are low after radical retropubic prostatectomy and positive margins J Urol 175 2006 140 144
6. I.M. Thompson, C.M. Tangen, and J. Paradelo Adjuvant radiotherapy for pathologically advanced prostate cancer JAMA 296 2006 2329 2335
7. A. Ochiai, T. Sotelo, and P. Troncoso Natural history of biochemical progression after radical prostatectomy based on length of a positive margin Urology 71 2008 308 312
8. R.E. Emerson, M.O. Koch, and T.D. Jones The influence of extent of surgical margin positivity on prostate specific antigen recurrence J Clin Pathol 58 2005 1028 1032
9. J.A. Eastham, M.W. Kattan, and R. Elyn Variation among individual surgeons in the rate of positive surgical margins in radical prostatectomy specimens J Urol 170 2003 2292 2295
10. T.H. Van der Kwast, M. Bolla, and H.V. Poppel Identification of patients with prostate cancer who benefit from immediate postoperative radiotherapy: EORTC 22911 J Clin Oncol 25 2007 4178 4186
11. A.N. Vis, F.H. Schroder, and T.H. van der Kwast The actual value of the surgical margin status as a predictor of disease progression in men with early prostate cancer Eur Urol 50 2006 258 265