The transport of soluble lysosomal hydrolases from the Golgi complex to lysosomes

The Golgi Apparatus: State of the Art 110 Years after Camillo Golgi's Discovery

Volumn , Issue , 2008, Pages 402-413

  Castino, Roberta ^a   Isidoro, Ciro ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 78149349007     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-211-76310-0_25     Document Type: Chapter

References (71)

1. Aerts JM, Schram AW, Strijland A, Van Weely S, Jonsson LM, Tager JM, Sorrell SH, Ginns EI, Barranger JA, Murray GJ (1988) Glucorebrosidase, a lysosomal enzyme that does not undergo oligosaccharide phosphorylation. Biochim Biophys Acta 964:303-308
2. Bao M, Booth JL, Elmendorf BJ, Canfield WM (1996) Bovine UDP-N-acetylglucosamine: lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase. I. Purification and subunit structure. J Biol Chem 271:31437-31445
3. Baranski TJ, Faust PL, Kornfeld S (1990) Generation of a lysosomal enzyme targeting signal in the secretory protein pepsinogen. Cell 63:281-291
4. Baranski TJ, Koelsch G, Hartsuck JA, Kornfeld S (1991) Mapping and molecular modeling of a recognition domain for lysosomal enzyme targeting. J Biol Chem 266:23365-23372
5. Braulke T, Gartung C, Hasilik A, Von Figura K (1987) Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes? J Cell Biol 104:1735-1742
6. Chavez CA, Bohnsack RN, Kudo M, Gotschall RR, Canfield WM, Dahms NM (2007) Domain 5 of the cation-independent mannose 6-phosphate receptor preferentially binds phosphodiesters (mannose 6-phosphate N-acetylglucosamine ester) Biochemistry. 46:12604-12617
7. Chikh K, Rodriguez C, Vey S, Vanier MT, Millat G (2005) Niemann-Pick type C disease: subcellular location and functional characterization of NPC2proteins with naturally occurring missense mutations. Hum Mutat 26:20-28
8. Cuozzo JW, Tao K, Wu QL, Young W, Sahagian GG (1995) Lysine-based structure in the proregion of procathepsin L is the recognition site for mannose phosphorylation. J Biol Chem 270:15611-15619
9. Czupalla C, Manusukoski H, Riedl T, Krause E, Hoflack B (2006) Proteomic analysis of lisosoma acid hydrolases secreted by osteoclasts: implications for lytic enzyme transport and bone metabolism. Mol Cell Proteomics 5:134-143
10. Devi GR, Byrd JC, Slentz DH, MacDonald RG (1998) Aninsulin-like growth factor II (IGF-II) affinity-enhancing domainlocalized within extracytoplasmic repeat 13 of the IGF-II/mannose 6-phosphate receptor. Mol Endocrinol 12:1661-1672
11. Diment S, Leech MS, Stahl PD (1988) Cathepsin D is membrane-associated in macrophage endosomes. J Biol Chem 263:6901-6907
12. Dittmer F, Von Figura K (1999) Phosphorylation of arylsulphatase A occurs through multiple interactions with the UDP-N-acetylglucosamine-1-phosphotransferase proximal and distal to its retrieval site by the KDEL receptor. Biochem J 340:729-736
13. Dittmer F, Pohlmann R, Von Figura K (1997) The phosphorylation pattern of oligosaccharides in secreted procathepsin D is glycosylation site-specific and independent of the expression of mannose 6-phosphate receptors. J Biol Chem 272:852-858
14. Faulhaber J, Fensom A, Hasilik A (1998) Abnormal lysosomal sorting with an enhanced secretion of cathepsinDprecursor molecules bearingmonoester phosphate groups. Eur J Cell Biol 77:134-140
15. Gelfman CM, Vogel P, Issa TM, Turner CA, Lee WS, Kornfeld S, Rice DS (2007) Mice lacking alpha/beta subunits of GlcNAc-1-phosphotransferase exhibit growth retardation, retinal degeneration, and secretory cell lesions. Invest Ophthalmol Vis Sci 48:5221-5228
16. Glickman JN, Kornfeld S (1993) Mannose 6-phosphate-independent targeting of lysosomal enzymes in I-cell disease B lymphoblasts. J Cell Biol 123:99-108
17. Hasilik A, Neufeld EF (1980) Biosynthesis of lysosomal enzymes in fibroblasts. Phosphorylation of mannose residues. J Biol Chem 255:4946-4950
18. Hirst J, Futter CE, Hopkins CR (1998) The kinetics of mannose 6-phosphate receptor trafficking in the endocytic pathway in HEp-2 cells: the receptor enters and rapidly leaves multivesicular endosomes without accumulating in a prelysosomal compartment. Mol Biol Cell 9:809-816
19. Isidoro C, Radons J, Baccino FM, Hasilik A (1990) Suppression of the 'uncovering' of mannose-6-phosphate residues in lysosomal enzymes in the presence of NH4Cl. Eur J Biochem 191:591-597
20. Isidoro C, Maggioni C, Demoz M, Pizzagalli A, Fra AM, Sitia R (1996) Exposed thiols confer localization in the endoplasmic reticulum by retention rather than retrieval. J Biol Chem 271:26138-26142
21. Isidoro C, Baccino FM, Hasilik A (1998) Human and hamster procathepsin D, although equally tagged with mannose-6-phosphate, are differentially targeted to lysosomes in transfected BHK cells. Cell Tissue Res 292:303-310
22. Journet A, Chapel A, Kieffer S, Roux F, Garin J (2002) Proteomic analysis of human lysosomes: application to monocytic and breast cancer cells. Proteomics 2:1026-1040
23. Kang JX, Li Y, Leaf A (1997) Mannose 6-phosphate/insulin-like growth factor-II is a receptor for retinoic acid. Proc Natl Acad Sci USA 95:13671-13676
24. Kasper D, Dittmer F, Von Figura K, Pohlmann R (1996) Neither type of mannose 6-phosphate receptor is sufficient for targeting of lysosomal enzymes along intracellular routes. J Cell Biol 134:615-623
25. Kollman K, Mutenda KE, Balleininger M, Eckermann E, Von Figura K, Schmidt B, Lubke T (2005) Identification of novel lysosomal matrix proteins by proteome analysis. Proteomics 5:3966-3978
26. Kornfeld S, Melman I (1989) The biogenesis of lysosomes. Annu Rev Cell Biol 5:483-525
27. Lazzarino DA, Gabel CA (1988) Biosynthesis of the mannose 6-phosphate recognition marker in transport-impaired mouse lymphoma cells. J Biol Chem 263:10118-10126
28. Lazzarino DA, Gabel CA (1989) Mannose processing is an important determinant in the assembly of prosphorylated high mannose-type oligosaccharides. J Biol Chem 264:5051-5023
29. Lefrancois S, Zeng J, Hassan AJ, Canuel M, Morales CR (2003) Thelysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin. EMBOJ 22:6430-6437
30. Leksa V, Godár S, Cebecauer M, Hilgert I, Breuss J, Weidle UH, Horejsí V, Binder BR, Stockinger H (2002) The N terminus of mannose 6-phosphate/insulin-like growth factor 2 receptor in regulation of fibrinolysis and cell migration. J Biol Chem 277:40575-40582
31. Lippincott-Schwartz J, Yuan LC, Bonifacino JS, Klausner RD (1989) Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell 56:801-813
32. Lippincott-Schwartz J, Donaldson JG, Schweizer A, Berger EG, Hauri HP, Yuan LC, Klausner RD (1990) Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin A suggests an ER recycling pathway. Cell 60:821-836
33. Lobel P, Dahms NM, Kornfeld S (1988) Cloning and sequence analysis of the cationindependent mannose 6-phosphate receptor. J Biol Chem 263:2563-2570
34. Ludwig T, Munier-Lehmann H, Bauer U, Hollinshead M, Ovitt C, Lobel P, Hoflack B (1994) Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts. EMBO J 13:3430-3437
35. Mari M, Bujny MV, Zeuscner D, Geerts WJC, Griffith J, Petersen CM, Cullen PJ, Klumperman J, Geuze HJ (2008) SNX1 defines and early endosomal recycling exit for sortilin and mannose 6-phosphate receptors. Traffic 9:380-393
36. McIntyre GF, Erickson AH (1991) Procathepsins L and D are membrane-bound in acidic microsomal vesicles. J Biol Chem 266:15438-15445
37. Munier-Lehmann H, Mauxion F, Bauer U, Lobel P, Hoflack B (1996) Re-expression of the mannose 6-phosphate receptors in receptor-deficient fibroblasts. Complementary function of the two mannose 6-phosphate receptors in lysosomal enzyme targeting. J Biol Chem 271:15166-15174
38. Nair P, Schaub BE, Huang K, Chen X, Murphy RF, Griffith JM, Geuze HJ, Rohrer J (2005) Characterization of the TGN exit signal of the human mannose 6-phosphate uncovering enzyme. J Cell Sci 271:15166-15174
39. Olson LJ, Hancock MK, Dix D, Kim JJ, Dahms NM (1999) Mutational analysis of the binding site residues of the bovine cation-dependent mannose 6-phosphate receptor. J Biol Chem 274:36905-36911
40. Olson LJ, Dahms NM, Kim JJ (2004) The N-terminal carbohydrate recognition site of the cation-independent mannose 6-phosphate receptor. J Biol Chem 279:34000-34009
41. Olson LJ, Hindgaul O, Dahms NM, Kim JJP (2008) Structural insight into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor. JBC http://www.jbc.org/cgi/doi/10.1074/jbc. M708994200
42. Owada M, Neufeld EF (1982) Is there a mechanism for introducing acid hydrolases into liver lysosomes that is independent of mannose 6-phosphate recognition? Evidence from I-cell disease. Biochem Biophys Res Commun 105:814-820
43. Pelham HR (1988) Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment. EMBO J 7:913-918
44. Pohlman R, Wendland M, Boeker C, Von Figura H (1995) The two mannose 6-phosphate receptors transport distinct complements of lysosomal proteins. J Biol Chem 270:27311-27318
45. Probst OC, Ton P, Svoboda B, Gannon A, Schuhmann W, Wieser J, Pohlmann R, Mach L (2006) The 46-kDa mannose 6-phosphate receptor does not depend on endosomal acidification for delivery of hydrolases to lysosomes. J Cell Sci 119:4935-4943
46. Purchio AF, Cooper JA, Brunner AM, Lioubin MN, Gentry LE, Kovacina KS, Roth RA Marquardt H (1988) Identification of mannose 6-phosphate in two asparaginelinked sugar chains of recombinant transforming growth factor-beta 1 precursor. J Biol Chem 1988 263:14211-14215
47. Qian M, Sleat DE, Zheng H, Moore D, Lobel P (2008) Proteomics analysis of serum mutant mice reveals lysosomal proteins selectively transported by each of the two mannose 6-phosphate receptors. Mol Cell Proteomics 7:58-70
48. Radons J, Isidoro C, Hasilik A (1990) Brefeldin A prevents uncovering but not phosphorylation of the recognition marker in cathepsin D. Biol Chem Hoppe-Seyler 371:567-573
49. Reczek D, Schwake M, Schroder J, Hughes H, Blanz J, Jin Xiaoying Brondyk W, Van Patten S, Edmunds T, Saftig P (2007) LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of b-glucocerebrosidase. Cell 131:770-783
50. Reddy ST, Chai W, Childs RA, Page JD, Feizi T, Dahms NM (2004) Identification of a low affinity mannose 6-phosphate-binding site in domain 5 of the cation-independent mannose 6-phosphate receptor. J Biol Chem 279:38658-38667
51. Rijnboutt S, Kal AJ, Geuze HJ, Aerts H, Strous GJ (1991) Mannose 6-phosphate-independent targeting of cathepsin D to lysosomes in HepG2 cells. J Biol Chem 266:23586-23592
52. Rohrer J, Kornfeld R (2001) Lysosomal hydrolase mannose 6-phosphate uncovering enzyme resides in the trans-Golgi network. Mol Biol Cell 12:1623-1631
53. Sampath D, Varki A, Freeze HH (1992) The spectrum of incomplete N-linked oligosaccharides synthesized by endothelial cells in the presence of brefeldin. J Biol Chem 267:4440-4455
54. Sleat DE, Lobel P (1997) Ligand binding specificities of the two mannose 6-phosphate receptors. J Biol Chem 272:731-738
55. Sleat DE, Lackland H, Wang Y, Sohar I, Xiao G, Li H, Lobel P (2005) The human brain mannose 6-phosphate glycoproteome: a complex mixture composed of multiple isoforms of many soluble lysosomal proteins. Proteomics 5:1520-1532
56. Sleat DE, Zheng H, Qian M, Lobel. P (2006) Identification of sites of mannose 6-phosphorylation on lysosomal proteins. Mol Cell Proteomics 5:686-701
57. Sohar I, Sleat D, Gong Liu C, Ludwig T, Lobel P (1998) Mouse mutants lacking the cationindependent mannose 6-phosphate/insulin-like growth factor II receptor are impaired in lysosomal enzyme transport: comparison of cation-independent and cation-dependent mannose 6-phosphate receptor-deficient mice. Biochem J 330:903-908
58. Sommerlade HJ, Selmer T, Ingendoh A, Gieselmann V, Von Figura K, Neifer K, Schmidt B (1994) Glycosylation and phosphorylation of arylsulfatase A. J Biol Chem 269:20977-20981
59. Steet R, Lee WS, Kornfeld S (2005) Identification of the minimal lysosomal enzyme recognition domain in cathepsin D. J Biol Chem 280:33318-33323
60. Tiede S, Storch S, Lubke T, Henrissat B, Bargal R, Raas-Rothschild A, Braulke T (2005) Mucopolidosis II is caused by mutations in GNPTA encoding tha alpha/beta GlcNac-1-phosphotransferase. Nat Med 11:1109-1112
61. Tong PY, Gregory W, Kornfeld S (1989) Ligand interactions of the cation-independent mannose 6-phosphate receptor. J Biol Chem 264:7962-7969
62. Tong PY, Kornfeld S (1989) Ligand interactions of the cation-independent mannose 6-phosphate receptor. J Biol Chem 264:7970-7975
63. Traub LM, Kornfeld S (1997) The trans-Golgi network: a late secretory sorting station. Curr Opin Cell Biol. 9:527-533
64. Van Dongen JM, Willemsen R, Ginns EI, Sips HJ, Tager JM, Barranger JA, Reuser AJ (1985) The subcellular localization of soluble and membrane-bound lysosomal enzymes in I-cell fibroblasts: a comparative immunocytochemical study. Eur J Cell Biol 39:179-189
65. Van Meel E, Klumperman J (2008) Imaging and imagination: understanding the endolysosomal system. Histochem Cell Biol 129:253-266
66. Varki A, Kornfeld S (1980) Identification of a rat liver alpha-N-acetylglucosaminyl phosphodiesterase capable of removing 'blocking' alpha-N-acetylglucosamine residues from phosphorylated high mannose oligosaccharides of lysosomal enzymes. J Biol Chem 255:8398-8401
67. Von Figura K (1991) Molecular recognition and targeting of lysosomal proteins. Curr Opin Cell Biol 3:642-646
68. Waheed A, Pohlmann R, Hasilik A, Von Figura K, Van Elsen A, Leroy JG (1982) Deficiency of UDP-N-acetylglucosamine: lysosomal enzyme N-acetylglucosamine-1-phosphotransferase in organs of I-cell patients. Biochem Biophys Res Commun 105:1052-1058
69. Waheed A, Gottschalk S, Hille A, Kreutler C, Pohlmann R, Braulke T, Hauser H, Geuze H, Von Figura K (1988) Human lysosomal acid phosphatase is transported as a transmembrane protein to lysosomes in transfected baby hamster kidney cells. EMBO J 7:2351-2358
70. Yaghootfam A, Schestag F, Dierks T, Gieselmann V (2003) Recognition of arylsulfatase A and B by the UDP-N-acetylglucosamine: lysosomal enzyme N-acetylglucosaminephosphotransferase. J Biol Chem 278:32653-32661
71. Zhu Y, Conner GE (1994) Intermolecular association of lysosomal protein precursors during biosynthesis. J Biol Chem 269:3846-3851