Tumor grade at margins of resection in radical prostatectomy specimens is an independent predictor of prognosis

Urology

Volumn 76, Issue 5, 2010, Pages 1206-1209

  Brimo, Fadi ^a   Partin, Alan W ^a   Epstein, Jonathan I ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADJUVANT THERAPY; ARTICLE; BLOOD LEVEL; CANCER GRADING; CONTROLLED STUDY; GLEASON SCORE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATECTOMY; TREATMENT OUTCOME; TUMOR RECURRENCE; UNIVARIATE ANALYSIS;

DISEASE PROGRESSION; HUMANS; MALE; PROGNOSIS; PROSTATE-SPECIFIC ANTIGEN; PROSTATECTOMY; PROSTATIC NEOPLASMS;

EID: 78149321822     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2010.03.090     Document Type: Article

References (24)

1. P.C. Walsh, A.W. Partin, and J.I. Epstein Cancer control and quality of life following anatomical radical retropubic prostatectomy: results at 10 years J Urol 152 1994 1831 1836
2. S.S. Chang, and M.S. Cookson Impact of positive surgical margins after radical prostatectomy Urology 68 2006 249 252
3. J.A. Wieder, and M.S. Soloway Incidence, etiology, location, prevention and treatment of positive surgical margins after radical prostatectomy for prostate cancer J Urol 160 1998 299 315
4. M. Ohori, and P.T. Scardino Localized prostate cancer Curr Probl Surg 39 2002 833 957
5. J.I. Epstein Pathologic assessment of the surgical specimen Urol Clin North Am 28 2001 567 594
6. C. Obek, S. Sadek, and S. Lai Positive surgical margins with radical retropubic prostatectomy: anatomic site-specific pathologic analysis and impact on prognosis Urology 54 1999 682 688
7. J.I. Epstein, G. Pizov, and P.C. Walsh Correlation of pathologic findings with progression after radical retropubic prostatectomy Cancer 71 1993 3582 3593
8. J.I. Epstein, A.W. Partin, and J. Sauvageot Prediction of progression following radical prostatectomy: a multivariate analysis of 721 men with long-term follow-up Am J Surg Pathol 20 1996 286 292
9. A.W. Partin, R.N. Borland, and J.I. Epstein Influence of wide excision of the neurovascular bundle(s) on prognosis in men with clinically localized prostate cancer with established capsular penetration J Urol 150 1993 142 148
10. J.I. Epstein Evaluation of radical prostatectomy capsular margins of resection: the significance of margins designated as negative, closely approaching, and positive Am J Surg Pathol 14 1990 626 632
11. L. Cheng, M.F. Darson, and E.J. Bergstralh Correlation of margin status and extraprostatic extension with progression of prostate carcinoma Cancer 86 1999 1775 1782
12. R.B. Watson, F. Civantos, and M.S. Soloway Positive surgical margins with radical prostatectomy: detailed pathological analysis and prognosis Urology 48 1996 80 90
13. M. Sofer, K.L. Hamilton-Nelson, and J.J. Schlesselman Risk of positive margins and biochemical recurrence in relation to nerve-sparing radical prostatectomy J Clin Oncol 20 2002 1853 1858
14. A. Ochiai, T. Sotelo, and P. Troncoso Natural history of biochemical progression after radical prostatectomy based on length of a positive margin Urology 71 2008 308 312
15. S. Shikanov, J. Song, and C. Royce Length of positive surgical margin after radical prostatectomy as a predictor of biochemical recurrence J Urol 182 2009 139 144
16. R.J. Babaian, P. Troncoso, and V.A. Bhadkamkar Analysis of clinicopathologic factors predicting outcome after radical prostatectomy Cancer 91 2001 1414 1422
17. J.I. Epstein, C.R. Pound, and A.W. Partin Disease progression following radical prostatectomy in men with Gleason score 7 tumor J Urol 160 1998 97 101
18. G.W. Hull, F. Rabbani, and F. Abbas Cancer control with radical prostatectomy alone in 1,000 consecutive patients J Urol 167 2002 528 534
19. M.W. Kattan, T.M. Wheeler, and P.T. Scardino Postoperative nomogram for disease recurrence after radical prostatectomy for prostate cancer J Clin Oncol 17 1999 1499 1507
20. J.A. Pettus, C.J. Weight, and C.J. Thompson Biochemical failure in men following radical retropubic prostatectomy: impact of surgical margin status and location J Urol 172 2004 129 132
21. P. Swindle, J.A. Eastham, and M. Ohori Do margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens J Urol 174 2005 903 907
22. M. Han, A.W. Partin, and C.R. Pound Long-term biochemical disease-free and cancer-specific survival following anatomic radical retropubic prostatectomy: the 15-year Johns Hopkins experience Urol Clin North Am 28 2001 555 565
23. S.J. Kausik, M.L. Blute, and T.J. Sebo Prognostic significance of positive surgical margins in patients with extraprostatic carcinoma after radical prostatectomy Cancer 95 2002 1215 1219
24. A.Y. Chuang, M.E. Nielsen, and D.J. Hernandez The significance of positive surgical margin in areas of capsular incision in otherwise organ confined disease at radical prostatectomy J Urol 178 2007 1306 1310