Sequential changes in the synaptic structural profile following long- term potentiation in the rat dentate gyrus: I. The intermediate maintenance phase

Synapse

Volumn 31, Issue 2, 1999, Pages 97-107

  Weeks, Andrew C W ^a   Ivanco, Tammy L ^b   Leboutillier, Janelle C ^a   Racine, Ronald J ^b   Petit, Ted L ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Hippocampus; LTP; Synaptic morphology; Synaptic plasticity

Indexed keywords

ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL ULTRASTRUCTURE; DENTATE GYRUS; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPSE;

EID: 0032919522     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199902)31:2<97::AID-SYN2>3.0.CO;2-D     Document Type: Article

References (41)

1. Adams B, Sazgar M, Osehobo P, Van der Zee CEEM, Diamond J, Fahanestock M, Racine RJ. 1997. Nerve growth factor accelerates seizure development, enhances mossy fiber sprouting, and attenuates seizure-induced decreases in neuronal density in the kindling model of epilepsy. J Neurosci 17:5288-5296.
2. Amaral DG, Witter MP. 1989. The three-dimensional organization of the hippocampal formation: A review of anatomical data. Neuroscience 31:571-591.
3. Anthes D, LeBoutillier JC, Petit TL. 1993. Structure and plasticity of newly formed adult synapses: A morphometric study in rat hippocampus. Brain Res 626:50-62.
4. Braendgaard H, Gundersen HJG. 1986. The impact of recent stereological advances on quantitative studies of the nervous system. J Neurosci Meth 18:39-78.
5. Buchs PA, Muller D. 1996. Induction of long-term potentiation is associated with major ultrastructural changes of activated synapses. Proc Natl Acad Sci USA 93:8040-8045.
6. Calverly R, Jones D. 1990. Contributions of dendritic spines and perforated synapses to synaptic plasticity. Brain Res Rev 15: 215-249.
7. Carlin R and Siekevitz P. 1983. Plasticity in the central nervous system: Do synapses divide? Proc Natl Acad Sci USA 80:3517-3521.
8. Chang F, Greenough W. 1984. Transient and enduring morphological correlates of synaptic activity and efficacy change in the rat hippocampal slice. Brain Res 309:35-46.
9. Cronin AJ, Satula TP, Desmond NL. 1987. Morphological changes in the hippocampal dentate gyrus accompanying kindling of the entorhinal cortex. Soc Neurosci Abst 13:947.
10. Desmond N, Levy W. 1983. Synaptic correlates of associative potentiation/depression: An ultrastructural study in the hippocampus. Brain Res 265:21-30.
11. Desmond N, Levy W. 1986. Changes in the postsynaptic density with long-term potentiation in the dentate gyrus. J Comp Neurol 253: 476-482.
12. Desmond N, Levy W. 1988. Synaptic interface surface area increases with long-term potentiation in the hippocampal dentate gyrus. Brain Res 453:308-314.
13. Desmond N, Levy W. 1990. Morphological correlates of long-term potentiation imply the modification of existing synapses, not synaptogenesis, in the hippocampal dentate gyrus. Synapse 5:139-143.
14. Dyson S, Jones D. 1984. Synaptic remodelling during development and maturation: Junction differentiation and splitting as a mechanism for modifying connectivity. Dev Brain Res 13:124-137.
15. Escobar ML, Barea-Rodriguez EJ, Derrick BE, Reyes JA, Martinez JL Jr. 1997. Opioid receptor modulation of mossy fiber synaptogenesis: Independence from long-term potentiation. Brain Res 751:330-335.
16. Fifkova E. 1985. Actin in the nervous system. Brain Res Rev 9: 187-215.
17. Geinisman Y. 1993. Perforated axospinous synapses with multiple, completely partitioned transmission zones: Probable structural intermediates in synaptic plasticity. Hippocampus 3:417-434.
18. Geinisman Y, deToledo-Morrell L, Morrell F. 1991. Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities. Brain Res 566:77-88.
19. Geinisman Y, deToledo-Morrell L, Morrell F, Persina IS, Rossi M. 1992a, Structural synaptic plasticity associated with the induction of long-term potentiation is preserved in the dentate gyrus of aged rats. Hippocampus 2:445-456.
20. Geinisman Y, Morrell F, deToledo-Morrell L. 1992b. Increase in the number of axospinous synapses with segmented postsynaptic densities following hippocampal kindling. Brain Res 569:341-347.
21. Geinisman Y, deToledo-Morrell L, Morrell F, Heller R, Rossi M, Parshall R. 1993. Structural synaptic correlate of long-term potentiation: Formation of axospinous synapses with multiple, completely partitioned transmission zones. Hippocampus 3:435-436.
22. Geinisman Y, deToledo-Morrell L, Morrell F, Persina IS, Beatty MA. 1996. Synapse restructuring associated with the maintenance phase of hippocampal long-term potentiation. J Comp Neurol 367: 413-123.
23. Greenough W, West R, DeVoogd T. 1978. Subsynaptic plate perforations: Changes with age and experience in the rat. Science 202:1096-1098.
24. Gundersen H. 1977. Notes on the estimation of the numerical density of arbitrary profiles: The edge effect. J Microscopy 111:219-223.
25. Jones D, Calverly R. 1991. Perforated and non-perforated synapses in rat neocortex: Three dimensional reconstructions. Brain Res 556: 247-258.
26. Jones DG, Harris RJ. 1995. An analysis of contemporary morphological concepts of synaptic remodelling in the CNS: The perforated synapses revisited. Rev Neurosci 6:177-219.
27. Jones D, Itarat W, Calverly R. 1992. Perforated synapses and plasticity: A developmental overview. Mol Neurobiol 5:217-228.
28. Landfield P, Deadwyler S. 1988. Long-term potentiation: From biophysics to behaviour. New York: Liss, Inc.
29. Lee KS, Schlottler F, Oliver M, Lynch G. 1980. Brief bursts of high-frequency stimulation produce two types of structural change in rat hippocampus. J Neurophysiol 44:247-258.
30. Lee KS, Oliver M, Schlottler F, Lynch G. 1981. Electron microscopic studies of brain slices: The effects of high frequency stimulation on dendritic ultrastructure. In: Kerkut GA, Wheal HV, editors. Electro-physiology of isolated mammalian CNS preparations. New York: Academic Press, pp 191-211.
31. Malenka R, Nicoll R. 1993. NMDA-receptor-dependent synaptic plasticity: Multiple forms and mechanisms. Trends Neurosci 16: 521-526.
32. Markus EJ, Petit TL. 1987. Neocortical synaptogenesis, aging and behavior: Lifespan development in the motor-sensory system of the rat. Exp Neurol 96:262-278.
33. Markus EJ, Petit T. 1989. Synaptic structural plasticity: Role of synaptic shape. Synapse 3:1-11.
34. McEachern JC, Shaw CA. 1996. An alternative to the LTP orthodoxy: A plasticity-pathology continuum model. Brain Res Rev 22:51-92.
35. McNaughton BL, Barnes CA, Andersen P. 1981. Synaptic efficacy and EPSP summation in granule cells of rat fascia dentata studied in vitro. J Neurophysiol 46:952-966.
36. Petit T. 1988. Synaptic plasticity and the structural basis of learning and memory. Neurology and neurobiology. In: Petit TL, Ivy GO, editors. Neural plasticity; A lifetime approach, Vol. 36. New York: Liss.
37. Petit TL. 1995. Structure and plasticity of the Hebbian synapse: The cascading events for memory storage. In: Spear LP, Spear NE, Woodruff M. editors. Neurobehavioral plasticity: Learning, development and response to brain insults. New York: Lawrence Erlbaum, pp 185-205.
38. Petit T, LeBoutillier J, Markus E, Milgram N. 1989. Synaptic structural plasticity following repetitive activation in the rat hippocampus. Exp Neurol 105:72-79.
39. Racine R, Moore K, Wicks S. 1991. Activation of the NMDA receptor: A correlate in the dentate gyrus field potential and its relationship to long-term potentiation and kindling. Brain Res 556:226-239.
40. Sutula T, He XX, Cavazos J, Scott G. 1988. Synaptic reorganization in the hippocampus induced by abnormal functional activity. Science 239:1147-1150.
41. Weeks ACW, Ivanco TL, LeBoutillier JL, Racine RJ, Petit TL. 1998. The degree of potentiation is associated with synaptic number during the maintenance of long-term potentiation in the rat dentate gyrus. Brain Res, in press.