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Volumn 171, Issue 2, 2010, Pages 556-565

Epileptic tolerance is associated with enduring neuroprotection and uncoupling of the relationship between CA3 damage, neuropeptide Y rearrangement and spontaneous seizures following intra-amygdala kainic acid-induced status epilepticus in mice

Author keywords

Epileptogenesis; Hippocampal sclerosis; Mossy fiber sprouting; Preconditioning; Status epilepticus

Indexed keywords

KAINIC ACID; NEUROPEPTIDE Y;

EID: 78149282950     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.09.003     Document Type: Article
Times cited : (19)

References (56)
  • 1
    • 0033826156 scopus 로고    scopus 로고
    • Electroshocks delay seizures and subsequent epileptogenesis but do not prevent neuronal damage in the lithium-pilocarpine model of epilepsy
    • Andre V., Ferrandon A., Marescaux C., Nehlig A. Electroshocks delay seizures and subsequent epileptogenesis but do not prevent neuronal damage in the lithium-pilocarpine model of epilepsy. Epilepsy Res 2000, 42:7-22.
    • (2000) Epilepsy Res , vol.42 , pp. 7-22
    • Andre, V.1    Ferrandon, A.2    Marescaux, C.3    Nehlig, A.4
  • 2
    • 0034675013 scopus 로고    scopus 로고
    • The lesional and epileptogenic consequences of lithium-pilocarpine-induced status epilepticus are affected by previous exposure to isolated seizures: effects of amygdala kindling and maximal electroshocks
    • Andre V., Ferrandon A., Marescaux C., Nehlig A. The lesional and epileptogenic consequences of lithium-pilocarpine-induced status epilepticus are affected by previous exposure to isolated seizures: effects of amygdala kindling and maximal electroshocks. Neuroscience 2000, 99:469-481.
    • (2000) Neuroscience , vol.99 , pp. 469-481
    • Andre, V.1    Ferrandon, A.2    Marescaux, C.3    Nehlig, A.4
  • 4
    • 33947212273 scopus 로고    scopus 로고
    • Gene expression changes after seizure preconditioning in the three major hippocampal cell layers
    • Borges K., Shaw R., Dingledine R. Gene expression changes after seizure preconditioning in the three major hippocampal cell layers. Neurobiol Dis 2007, 26:66-77.
    • (2007) Neurobiol Dis , vol.26 , pp. 66-77
    • Borges, K.1    Shaw, R.2    Dingledine, R.3
  • 5
    • 9644295776 scopus 로고    scopus 로고
    • Epilepsy induced by extended amygdala-kindling in rats: lack of clear association between development of spontaneous seizures and neuronal damage
    • Brandt C., Ebert U., Loscher W. Epilepsy induced by extended amygdala-kindling in rats: lack of clear association between development of spontaneous seizures and neuronal damage. Epilepsy Res 2004, 62:135-156.
    • (2004) Epilepsy Res , vol.62 , pp. 135-156
    • Brandt, C.1    Ebert, U.2    Loscher, W.3
  • 6
    • 0037466759 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor blockade after status epilepticus protects against limbic brain damage but not against epilepsy in kainate model of temporal lobe epilepsy
    • Brandt C., Potschka H., Loscher W., Ebert U. N-methyl-D-aspartate receptor blockade after status epilepticus protects against limbic brain damage but not against epilepsy in kainate model of temporal lobe epilepsy. Neuroscience 2003, 118:727-740.
    • (2003) Neuroscience , vol.118 , pp. 727-740
    • Brandt, C.1    Potschka, H.2    Loscher, W.3    Ebert, U.4
  • 7
    • 53149145699 scopus 로고    scopus 로고
    • Minimal latency to hippocampal epileptogenesis and clinical epilepsy after perforant pathway stimulation-induced status epilepticus in awake rats
    • Bumanglag A.V., Sloviter R.S. Minimal latency to hippocampal epileptogenesis and clinical epilepsy after perforant pathway stimulation-induced status epilepticus in awake rats. J Comp Neurol 2008, 510:561-580.
    • (2008) J Comp Neurol , vol.510 , pp. 561-580
    • Bumanglag, A.V.1    Sloviter, R.S.2
  • 8
    • 0033947122 scopus 로고    scopus 로고
    • Kainic acid induction of mossy fiber sprouting: dependence on mouse strain
    • Cantallops I., Routtenberg A. Kainic acid induction of mossy fiber sprouting: dependence on mouse strain. Hippocampus 2000, 10:269-273.
    • (2000) Hippocampus , vol.10 , pp. 269-273
    • Cantallops, I.1    Routtenberg, A.2
  • 9
    • 0019952583 scopus 로고
    • Long-term effects of intrahippocampal kainic acid injection in rats: a method for inducing spontaneous recurrent seizures
    • Cavalheiro E.A., Riche D.A., Le Gal La Salle G. Long-term effects of intrahippocampal kainic acid injection in rats: a method for inducing spontaneous recurrent seizures. Electroencephalogr Clin Neurophysiol 1982, 53:581-589.
    • (1982) Electroencephalogr Clin Neurophysiol , vol.53 , pp. 581-589
    • Cavalheiro, E.A.1    Riche, D.A.2    Le Gal La Salle, G.3
  • 10
    • 0025787898 scopus 로고
    • Mossy fiber synaptic reorganization induced by kindling: time course of development, progression, and permanence
    • Cavazos J.E., Golarai G., Sutula T.P. Mossy fiber synaptic reorganization induced by kindling: time course of development, progression, and permanence. J Neurosci 1991, 11:2795-2803.
    • (1991) J Neurosci , vol.11 , pp. 2795-2803
    • Cavazos, J.E.1    Golarai, G.2    Sutula, T.P.3
  • 11
    • 0024208367 scopus 로고
    • Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats
    • Cronin J., Dudek F.E. Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats. Brain Res 1988, 474:181-184.
    • (1988) Brain Res , vol.474 , pp. 181-184
    • Cronin, J.1    Dudek, F.E.2
  • 12
    • 0035975623 scopus 로고    scopus 로고
    • Molecular events involved in neuronal death induced in the mouse hippocampus by in-vivo injection of kainic acid
    • Djebaili M., Lerner-Natoli M., Pascale M., Baille V., Bockaert J., Rondouin G. Molecular events involved in neuronal death induced in the mouse hippocampus by in-vivo injection of kainic acid. Brain Res Mol Brain Res 2001, 93:190-198.
    • (2001) Brain Res Mol Brain Res , vol.93 , pp. 190-198
    • Djebaili, M.1    Lerner-Natoli, M.2    Pascale, M.3    Baille, V.4    Bockaert, J.5    Rondouin, G.6
  • 13
    • 0036333854 scopus 로고    scopus 로고
    • Delayed sclerosis, neuroprotection, and limbic epileptogenesis after status epilepticus in the rat
    • Ebert U., Brandt C., Loscher W. Delayed sclerosis, neuroprotection, and limbic epileptogenesis after status epilepticus in the rat. Epilepsia 2002, 43:86-95.
    • (2002) Epilepsia , vol.43 , pp. 86-95
    • Ebert, U.1    Brandt, C.2    Loscher, W.3
  • 14
    • 0030921492 scopus 로고    scopus 로고
    • Induction of tolerance and mossy fibre neuropeptide-Y expression in the contralateral hippocampus following a unilateral intrahippocampal kainic acid injection in the rat
    • El Bahh B., Lurton D., Sundstrom L.E., Rougier A. Induction of tolerance and mossy fibre neuropeptide-Y expression in the contralateral hippocampus following a unilateral intrahippocampal kainic acid injection in the rat. Neurosci Lett 1997, 227:135-139.
    • (1997) Neurosci Lett , vol.227 , pp. 135-139
    • El Bahh, B.1    Lurton, D.2    Sundstrom, L.E.3    Rougier, A.4
  • 16
    • 33745763116 scopus 로고    scopus 로고
    • Cerebral preconditioning and ischaemic tolerance
    • Gidday J.M. Cerebral preconditioning and ischaemic tolerance. Nat Rev Neurosci 2006, 7:437-448.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 437-448
    • Gidday, J.M.1
  • 18
    • 34248549590 scopus 로고    scopus 로고
    • Stereological analysis of GluR2-immunoreactive hilar neurons in the pilocarpine model of temporal lobe epilepsy: correlation of cell loss with mossy fiber sprouting
    • Jiao Y., Nadler J.V. Stereological analysis of GluR2-immunoreactive hilar neurons in the pilocarpine model of temporal lobe epilepsy: correlation of cell loss with mossy fiber sprouting. Exp Neurol 2007, 205:569-582.
    • (2007) Exp Neurol , vol.205 , pp. 569-582
    • Jiao, Y.1    Nadler, J.V.2
  • 19
    • 56349130733 scopus 로고    scopus 로고
    • Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways
    • Jimenez-Mateos E.M., Hatazaki S., Johnson M.B., Bellver-Estelles C., Mouri G., Bonner C., Prehn J.H., Meller R., Simon R.P., Henshall D.C. Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiol Dis 2008, 32:442-453.
    • (2008) Neurobiol Dis , vol.32 , pp. 442-453
    • Jimenez-Mateos, E.M.1    Hatazaki, S.2    Johnson, M.B.3    Bellver-Estelles, C.4    Mouri, G.5    Bonner, C.6    Prehn, J.H.7    Meller, R.8    Simon, R.P.9    Henshall, D.C.10
  • 21
    • 0028158217 scopus 로고
    • Hippocampal kindling protects several structures from the neuronal damage resulting from kainic acid-induced status epilepticus
    • Kelly M.E., McIntyre D.C. Hippocampal kindling protects several structures from the neuronal damage resulting from kainic acid-induced status epilepticus. Brain Res 1994, 634:245-256.
    • (1994) Brain Res , vol.634 , pp. 245-256
    • Kelly, M.E.1    McIntyre, D.C.2
  • 22
    • 67650294279 scopus 로고    scopus 로고
    • Hippocampal injury, atrophy, synaptic reorganization, and epileptogenesis after perforant pathway stimulation-induced status epilepticus in the mouse
    • Kienzler F., Norwood B.A., Sloviter R.S. Hippocampal injury, atrophy, synaptic reorganization, and epileptogenesis after perforant pathway stimulation-induced status epilepticus in the mouse. J Comp Neurol 2009, 515:181-196.
    • (2009) J Comp Neurol , vol.515 , pp. 181-196
    • Kienzler, F.1    Norwood, B.A.2    Sloviter, R.S.3
  • 23
    • 0025649042 scopus 로고
    • Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy
    • Leite J.P., Bortolotto Z.A., Cavalheiro E.A. Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy. Neurosci Biobehav Rev 1990, 14:511-517.
    • (1990) Neurosci Biobehav Rev , vol.14 , pp. 511-517
    • Leite, J.P.1    Bortolotto, Z.A.2    Cavalheiro, E.A.3
  • 25
    • 0000738525 scopus 로고    scopus 로고
    • Hippocampal sclerosis
    • Lippincott-Raven Publishers, Philadelphia, PA, J.J. Engel, T.A. Pedley (Eds.)
    • Mathern G.W., Babb T.L., Armstrong D.L. Hippocampal sclerosis. Epilepsy: a comprehensive textbook 1997, Vol. 13:133-155. Lippincott-Raven Publishers, Philadelphia, PA. J.J. Engel, T.A. Pedley (Eds.).
    • (1997) Epilepsy: a comprehensive textbook , vol.13 , pp. 133-155
    • Mathern, G.W.1    Babb, T.L.2    Armstrong, D.L.3
  • 26
    • 44349104927 scopus 로고    scopus 로고
    • Proliferating progenitor cells: a required cellular element for induction of ischemic tolerance in the brain
    • Maysami S., Lan J.Q., Minami M., Simon R.P. Proliferating progenitor cells: a required cellular element for induction of ischemic tolerance in the brain. J Cereb Blood Flow Metab 2008, 28:1104-1113.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1104-1113
    • Maysami, S.1    Lan, J.Q.2    Minami, M.3    Simon, R.P.4
  • 27
    • 0027527126 scopus 로고
    • Excitotoxicity and selective neuronal loss in epilepsy
    • Meldrum B.S. Excitotoxicity and selective neuronal loss in epilepsy. Brain Pathol 1993, 3:405-412.
    • (1993) Brain Pathol , vol.3 , pp. 405-412
    • Meldrum, B.S.1
  • 29
    • 2942574539 scopus 로고    scopus 로고
    • Kindling and status epilepticus models of epilepsy: rewiring the brain
    • Morimoto K., Fahnestock M., Racine R.J. Kindling and status epilepticus models of epilepsy: rewiring the brain. Prog Neurobiol 2004, 73:1-60.
    • (2004) Prog Neurobiol , vol.73 , pp. 1-60
    • Morimoto, K.1    Fahnestock, M.2    Racine, R.J.3
  • 30
    • 44449145323 scopus 로고    scopus 로고
    • Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice
    • Mouri G., Jimenez-Mateos E., Engel T., Dunleavy M., Hatazaki S., Paucard A., Matsushima S., Taki W., Henshall D.C. Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice. Brain Res 2008, 1213:140-151.
    • (2008) Brain Res , vol.1213 , pp. 140-151
    • Mouri, G.1    Jimenez-Mateos, E.2    Engel, T.3    Dunleavy, M.4    Hatazaki, S.5    Paucard, A.6    Matsushima, S.7    Taki, W.8    Henshall, D.C.9
  • 31
    • 4544350090 scopus 로고    scopus 로고
    • Progression of brain damage after status epilepticus and its association with epileptogenesis: a quantitative MRI study in a rat model of temporal lobe epilepsy
    • Nairismagi J., Grohn O.H., Kettunen M.I., Nissinen J., Kauppinen R.A., Pitkanen A. Progression of brain damage after status epilepticus and its association with epileptogenesis: a quantitative MRI study in a rat model of temporal lobe epilepsy. Epilepsia 2004, 45:1024-1034.
    • (2004) Epilepsia , vol.45 , pp. 1024-1034
    • Nairismagi, J.1    Grohn, O.H.2    Kettunen, M.I.3    Nissinen, J.4    Kauppinen, R.A.5    Pitkanen, A.6
  • 33
    • 0038368825 scopus 로고    scopus 로고
    • Administration of caspase 3 inhibitor during and after status epilepticus in rat: effect on neuronal damage and epileptogenesis
    • Narkilahti S., Nissinen J., Pitkanen A. Administration of caspase 3 inhibitor during and after status epilepticus in rat: effect on neuronal damage and epileptogenesis. Neuropharmacology 2003, 44:1068-1088.
    • (2003) Neuropharmacology , vol.44 , pp. 1068-1088
    • Narkilahti, S.1    Nissinen, J.2    Pitkanen, A.3
  • 34
    • 0033992158 scopus 로고    scopus 로고
    • A new model of chronic temporal lobe epilepsy induced by electrical stimulation of the amygdala in rat
    • Nissinen J., Halonen T., Koivisto E., Pitkanen A. A new model of chronic temporal lobe epilepsy induced by electrical stimulation of the amygdala in rat. Epilepsy Res 2000, 38:177-205.
    • (2000) Epilepsy Res , vol.38 , pp. 177-205
    • Nissinen, J.1    Halonen, T.2    Koivisto, E.3    Pitkanen, A.4
  • 35
    • 0034939296 scopus 로고    scopus 로고
    • Is mossy fiber sprouting present at the time of the first spontaneous seizures in rat experimental temporal lobe epilepsy?
    • Nissinen J., Lukasiuk K., Pitkanen A. Is mossy fiber sprouting present at the time of the first spontaneous seizures in rat experimental temporal lobe epilepsy?. Hippocampus 2001, 11:299-310.
    • (2001) Hippocampus , vol.11 , pp. 299-310
    • Nissinen, J.1    Lukasiuk, K.2    Pitkanen, A.3
  • 37
    • 77954576989 scopus 로고    scopus 로고
    • Classic hippocampal sclerosis and hippocampal-onset epilepsy produced by a single "cryptic" episode of focal hippocampal excitation in awake rats
    • Norwood B.A., Bumanglag A.V., Osculati F., Sbarbati A., Marzola P., Nicolato E., Fabene P.F., Sloviter R.S. Classic hippocampal sclerosis and hippocampal-onset epilepsy produced by a single "cryptic" episode of focal hippocampal excitation in awake rats. J Comp Neurol 2010, 518:3381-3407.
    • (2010) J Comp Neurol , vol.518 , pp. 3381-3407
    • Norwood, B.A.1    Bumanglag, A.V.2    Osculati, F.3    Sbarbati, A.4    Marzola, P.5    Nicolato, E.6    Fabene, P.F.7    Sloviter, R.S.8
  • 39
    • 0018956879 scopus 로고
    • Spontaneously recurrent seizures after intracerebral injections of kainic acid in rat: a possible model of human temporal lobe epilepsy
    • Pisa M., Sanberg P.R., Corcoran M.E., Fibiger H.C. Spontaneously recurrent seizures after intracerebral injections of kainic acid in rat: a possible model of human temporal lobe epilepsy. Brain Res 1980, 200:481-487.
    • (1980) Brain Res , vol.200 , pp. 481-487
    • Pisa, M.1    Sanberg, P.R.2    Corcoran, M.E.3    Fibiger, H.C.4
  • 40
    • 0037069268 scopus 로고    scopus 로고
    • Drug-mediated neuroprotection and anti-epileptogenesis
    • Pitkanen A. Drug-mediated neuroprotection and anti-epileptogenesis. Neurology 2002, 59:S27-S33.
    • (2002) Neurology , vol.59
    • Pitkanen, A.1
  • 41
    • 0036345477 scopus 로고    scopus 로고
    • Efficacy of current antiepileptics to prevent neurodegeneration in epilepsy models
    • Pitkanen A. Efficacy of current antiepileptics to prevent neurodegeneration in epilepsy models. Epilepsy Res 2002, 50:141-160.
    • (2002) Epilepsy Res , vol.50 , pp. 141-160
    • Pitkanen, A.1
  • 42
    • 33750941236 scopus 로고    scopus 로고
    • Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy
    • Raol Y.H., Lund I.V., Bandyopadhyay S., Zhang G., Roberts D.S., Wolfe J.H., Russek S.J., Brooks-Kayal A.R. Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy. J Neurosci 2006, 26:11342-11346.
    • (2006) J Neurosci , vol.26 , pp. 11342-11346
    • Raol, Y.H.1    Lund, I.V.2    Bandyopadhyay, S.3    Zhang, G.4    Roberts, D.S.5    Wolfe, J.H.6    Russek, S.J.7    Brooks-Kayal, A.R.8
  • 43
    • 0028909428 scopus 로고
    • Epileptic tolerance: prior seizures protect against seizure-induced neuronal injury
    • Sasahira M., Lowry T., Simon R.P., Greenberg D.A. Epileptic tolerance: prior seizures protect against seizure-induced neuronal injury. Neurosci Lett 1995, 185:95-98.
    • (1995) Neurosci Lett , vol.185 , pp. 95-98
    • Sasahira, M.1    Lowry, T.2    Simon, R.P.3    Greenberg, D.A.4
  • 44
    • 0023129330 scopus 로고
    • Decreased hippocampal inhibition and a selective loss of interneurons in experimental epilepsy
    • Sloviter R.S. Decreased hippocampal inhibition and a selective loss of interneurons in experimental epilepsy. Science 1987, 235:73-76.
    • (1987) Science , vol.235 , pp. 73-76
    • Sloviter, R.S.1
  • 45
    • 57249094423 scopus 로고    scopus 로고
    • Hippocampal epileptogenesis in animal models of mesial temporal lobe epilepsy with hippocampal sclerosis: the importance of the "latent period" and other concepts
    • Sloviter R.S. Hippocampal epileptogenesis in animal models of mesial temporal lobe epilepsy with hippocampal sclerosis: the importance of the "latent period" and other concepts. Epilepsia 2008, 49(Suppl 9):85-92.
    • (2008) Epilepsia , vol.49 , Issue.SUPPL 9 , pp. 85-92
    • Sloviter, R.S.1
  • 46
    • 35748958399 scopus 로고    scopus 로고
    • On the relevance of prolonged convulsive status epilepticus in animals to the etiology and neurobiology of human temporal lobe epilepsy
    • Sloviter R.S., Zappone C.A., Bumanglag A.V., Norwood B.A., Kudrimoti H. On the relevance of prolonged convulsive status epilepticus in animals to the etiology and neurobiology of human temporal lobe epilepsy. Epilepsia 2007, 48(Suppl 8):6-10.
    • (2007) Epilepsia , vol.48 , Issue.SUPPL 8 , pp. 6-10
    • Sloviter, R.S.1    Zappone, C.A.2    Bumanglag, A.V.3    Norwood, B.A.4    Kudrimoti, H.5
  • 47
    • 0024444281 scopus 로고
    • Mossy fiber synaptic reorganization in the epileptic human temporal lobe
    • Sutula T., Cascino G., Cavazos J., Parada I., Ramirez L. Mossy fiber synaptic reorganization in the epileptic human temporal lobe. Ann Neurol 1989, 26:321-330.
    • (1989) Ann Neurol , vol.26 , pp. 321-330
    • Sutula, T.1    Cascino, G.2    Cavazos, J.3    Parada, I.4    Ramirez, L.5
  • 48
    • 0027034173 scopus 로고
    • Assessing the functional significance of mossy fiber sprouting
    • Sutula T.P., Golarai G., Cavazos J. Assessing the functional significance of mossy fiber sprouting. Epilepsy Res Suppl 1992, 7:251-259.
    • (1992) Epilepsy Res Suppl , vol.7 , pp. 251-259
    • Sutula, T.P.1    Golarai, G.2    Cavazos, J.3
  • 49
    • 75849128324 scopus 로고    scopus 로고
    • Hippocampal damage after intra-amygdala kainic acid-induced status epilepticus and seizure preconditioning-mediated neuroprotection in SJL mice
    • Tanaka K., Jimenez-Mateos E.M., Matsushima S., Taki W., Henshall D.C. Hippocampal damage after intra-amygdala kainic acid-induced status epilepticus and seizure preconditioning-mediated neuroprotection in SJL mice. Epilepsy Res 2010, 88:151-161.
    • (2010) Epilepsy Res , vol.88 , pp. 151-161
    • Tanaka, K.1    Jimenez-Mateos, E.M.2    Matsushima, S.3    Taki, W.4    Henshall, D.C.5
  • 51
    • 34548221500 scopus 로고    scopus 로고
    • Neuropeptide Y regulates recurrent mossy fiber synaptic transmission less effectively in mice than in rats: correlation with Y2 receptor plasticity
    • Tu B., Jiao Y., Herzog H., Nadler J.V. Neuropeptide Y regulates recurrent mossy fiber synaptic transmission less effectively in mice than in rats: correlation with Y2 receptor plasticity. Neuroscience 2006, 143:1085-1094.
    • (2006) Neuroscience , vol.143 , pp. 1085-1094
    • Tu, B.1    Jiao, Y.2    Herzog, H.3    Nadler, J.V.4
  • 52
    • 14044276408 scopus 로고    scopus 로고
    • Spontaneous release of neuropeptide Y tonically inhibits recurrent mossy fiber synaptic transmission in epileptic brain
    • Tu B., Timofeeva O., Jiao Y., Nadler J.V. Spontaneous release of neuropeptide Y tonically inhibits recurrent mossy fiber synaptic transmission in epileptic brain. J Neurosci 2005, 25:1718-1729.
    • (2005) J Neurosci , vol.25 , pp. 1718-1729
    • Tu, B.1    Timofeeva, O.2    Jiao, Y.3    Nadler, J.V.4
  • 53
    • 0021684071 scopus 로고
    • Seizures produced by pilocarpine in mice: a behavioral, electroencephalographic and morphological analysis
    • Turski W.A., Cavalheiro E.A., Bortolotto Z.A., Mello L.M., Schwarz M., Turski L. Seizures produced by pilocarpine in mice: a behavioral, electroencephalographic and morphological analysis. Brain Res 1984, 321:237-253.
    • (1984) Brain Res , vol.321 , pp. 237-253
    • Turski, W.A.1    Cavalheiro, E.A.2    Bortolotto, Z.A.3    Mello, L.M.4    Schwarz, M.5    Turski, L.6
  • 54
    • 0027930954 scopus 로고
    • Enhanced neuropeptide Y release in the hippocampus is associated with chronic seizure susceptibility in kainic acid treated rats
    • Vezzani A., Civenni G., Rizzi M., Monno A., Messali S., Samanin R. Enhanced neuropeptide Y release in the hippocampus is associated with chronic seizure susceptibility in kainic acid treated rats. Brain Res 1994, 660:138-143.
    • (1994) Brain Res , vol.660 , pp. 138-143
    • Vezzani, A.1    Civenni, G.2    Rizzi, M.3    Monno, A.4    Messali, S.5    Samanin, R.6
  • 55
    • 14744289621 scopus 로고    scopus 로고
    • Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: contribution of delayed neuronal cell death to seizure-induced neuronal injury
    • Weise J., Engelhorn T., Dorfler A., Aker S., Bahr M., Hufnagel A. Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: contribution of delayed neuronal cell death to seizure-induced neuronal injury. Neurobiol Dis 2005, 18:582-590.
    • (2005) Neurobiol Dis , vol.18 , pp. 582-590
    • Weise, J.1    Engelhorn, T.2    Dorfler, A.3    Aker, S.4    Bahr, M.5    Hufnagel, A.6


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