-
1
-
-
0004064018
-
-
Washington, DC , Office of the Surgeon General at TMM Publications, Borden Institute
-
Sidell FR, Takafuji ET, Franz DR: Medical Aspects of Chemical and Biological Warfare, Textbook of Military Medicine. Washington, DC , Office of the Surgeon General at TMM Publications, Borden Institute, 1997.
-
(1997)
Medical Aspects of Chemical and Biological Warfare Textbook of Military Medicine
-
-
Sidell, F.R.1
Takafuji, E.T.2
Franz, D.R.3
-
2
-
-
0014759764
-
The use of carbamates and atropine in the protection of animals against poisoning by 1,2,2-trimethylpropyl methyl-phosphonofluoridate
-
Berry WK, Davies DR: The use of carbamates and atropine in the protection of animals against poisoning by 1,2,2-trimethylpropyl methyl- phosphonofluoridate. Biochem Pharmacol 1970; 19: 927-34.
-
(1970)
Biochem Pharmacol
, vol.19
, pp. 927-934
-
-
Berry, W.K.1
Davies, D.R.2
-
3
-
-
0017807282
-
The protection of animals against organophosphate poisoning by pretreatment with a carbamate
-
Gordon JJ, Leadbeater L, Maidment MP: The protection of animals against organophosphate poisoning by pretreatment with a carbamate , Toxicol Appl Pharmacol 1978; 43: 207-16.
-
(1978)
Toxicol Appl Pharmacol
, vol.43
, pp. 207-216
-
-
Gordon, J.J.1
Leadbeater, L.2
Maidment, M.P.3
-
4
-
-
33745664204
-
Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetyl-cholinesterase by highly toxic organophosphorus compounds
-
Eckert S, Eyer P, Muckter H, Worek F: Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetyl-cholinesterase by highly toxic organophosphorus compounds. Biochem Pharmacol 2006; 72: 344-57.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 344-357
-
-
Eckert, S.1
Eyer, P.2
Muckter, H.3
Worek, F.4
-
5
-
-
0011317599
-
Anticholinesterase agents
-
Edited by Goodman LS, Gilman A. New York, MacMillan Publishing Co
-
Koelle GB: Anticholinesterase agents. In: The Pharmacologic Basis of Therapeutics, Ed 5. Edited by Goodman LS, Gilman A. New York, MacMillan Publishing Co , 1975
-
(1975)
In the Pharmacologic Basis of Therapeutics Ed 5
-
-
Koelle, G.B.1
-
6
-
-
0026008682
-
Anticonvulsant actions of anticholinergic drugs in soman poisoning
-
Capacio BR , Shih T-M : Anticonvulsant actions of anticholinergic drugs in soman poisoning. Epilepsia 1991; 32(5): 604-14.
-
(1991)
Epilepsia
, vol.32
, Issue.5
, pp. 604-614
-
-
Capacio, B.R.1
Shih, T.-M.2
-
7
-
-
77957182393
-
Efficacy comparison of scopolamine and diazepam against soman-induced debilitation in guinea pigs
-
DOI 10.1006/faat.1994.1065
-
Anderson DR, Gennings C, Carter WH, et al: Efficacy comparison of scopolamine and diazepam against soman-induced debilitation in guinea pigs. Fundam Appl Toxicol 1994; 22(4): 588-93. (Pubitemid 24194721)
-
(1994)
Fundamental and Applied Toxicology
, vol.22
, Issue.4
, pp. 588-593
-
-
Anderson, D.R.1
Gennings, C.2
Carter, W.H.3
Harris, L.W.4
Lennox, W.J.5
Bowersox, S.L.6
Solana, R.P.7
-
8
-
-
0027988232
-
Efficacy comparison of scopolamine (SCP) and diazepam (DZ) against soman-induced lethality in guinea pigs
-
Harris LW, Gennings C, Carter WH, et al: Efficacy comparison of scopolamine (SCP) and diazepam (DZ) against soman-induced lethality in guinea pigs. Drug Chem Toxicol 1994; 17(1): 35-50. (Pubitemid 24367324)
-
(1994)
Drug and Chemical Toxicology
, vol.17
, Issue.1
, pp. 35-50
-
-
Harris, L.W.1
Gennings, C.2
Carter, W.H.3
Anderson, D.R.4
Lennox, W.J.5
Bowersox, S.L.6
Solana, R.P.7
-
9
-
-
0033962354
-
Scopolamine augments the efficacy of physostigmine against soman poisoning in guinea pigs
-
Philippens IH , Melchers BP, Olivier B , Bruijnzeel PL : Scopolamine augments the efficacy of physostigmine against soman poisoning in guinea pigs. Pharmacol Biochem Behav 2000; 65(1): 175-82.
-
(2000)
Pharmacol Biochem Behav
, vol.65
, Issue.1
, pp. 175-182
-
-
Philippens, I.H.1
Melchers, B.P.2
Olivier, B.3
Bruijnzeel, P.L.4
-
10
-
-
0036745179
-
Physostigmine and hyoscine improves protection against the lethal and incapacitating effects of nerve agent poisoning in the guinea pig
-
Wetherell J , Hall T, Passingham S : Physostigmine and hyoscine improves protection against the lethal and incapacitating effects of nerve agent poisoning in the guinea pig. Neurotoxicology 2002; 23(3): 341-9.
-
(2002)
Neurotoxicology
, vol.23
, Issue.3
, pp. 341-349
-
-
Wetherell, J.1
Hall, T.2
Passingham, S.3
-
11
-
-
0344643406
-
Assessment of a combination of physostigmine and scopolamine as a pretreatment against the behavioral effects of organophosphates in the common marmoset (Callithrix jacchus)
-
Muggleton NG , Bowditch AP, Crofts HS , Scott EA , Pearce PC : Assessment of a combination of physostigmine and scopolamine as a pretreatment against the behavioral effects of organophosphates in the common marmoset (Callithrix jacchus). Psychopharmacology (Berl) 2003; 166(3): 212-20.
-
(2003)
Psychopharmacology (Berl)
, vol.166
, Issue.3
, pp. 212-220
-
-
Muggleton, N.G.1
Bowditch, A.P.2
Crofts, H.S.3
Scott, E.A.4
Pearce, P.C.5
-
12
-
-
0031029040
-
The importance of cholinolytic drug selection for the efficacy of HI-6 against soman in rats
-
Kassa J: The importance of cholinolytic drug selection for the efficacy of HI-6 against soman in rats. Toxicology 1997; 116: 147-52.
-
(1997)
Toxicology
, vol.116
, pp. 147-152
-
-
Kassa, J.1
-
13
-
-
0034706922
-
The influence of anticholinergic drug selection on the efficacy of antidotal treatment of soman-poisoned rats
-
Kassa J, Fusek J: The influence of anticholinergic drug selection on the efficacy of antidotal treatment of soman-poisoned rats. Toxicology 2000; 154: 67-73.
-
(2000)
Toxicology
, vol.154
, pp. 67-73
-
-
Kassa, J.1
Fusek, J.2
-
14
-
-
0033374581
-
Anticonvulsant treatment of nerve agent seizures: Anticholin-ergics versus diazepam in soman-intoxicated guinea pigs
-
McDonough JH Jr, Zoeffel LD, McMonagle J, Copeland TL, Smith CD, Shih T-M : Anticonvulsant treatment of nerve agent seizures: anticholin-ergics versus diazepam in soman-intoxicated guinea pigs. Epilepsy Res 2000; 38: 1-14.
-
(2000)
Epilepsy Res
, vol.38
, pp. 1-14
-
-
McDonough Jr., J.H.1
Zoeffel, L.D.2
McMonagle, J.3
Copeland, T.L.4
Smith, C.D.5
Shih, T.-M.6
-
15
-
-
0037446246
-
Control of nerve agent-induced seizure is critical for neuroprotection and survival
-
Shih T-M, Duniho SM, McDonough JH: Control of nerve agent-induced seizure is critical for neuroprotection and survival. Toxicol Appl Pharmacol 2003; 188: 69-80.
-
(2003)
Toxicol Appl Pharmacol
, vol.188
, pp. 69-80
-
-
Shih, T.-M.1
Duniho, S.M.2
McDonough, J.H.3
-
16
-
-
0015549102
-
Atropine, scopolamine and ditran: Comparative pharmacology and antagonists in man
-
Ketchum JS, Sidell FR, Crowell EB Jr, Aghajanian GK, Hayes AH Jr: Atropine, scopolamine and ditran: comparative pharmacology and antagonists in man. Psychopharmacology (Berl) 1973; 28: 121-45.
-
(1973)
Psychopharmacology (Berl)
, vol.28
, pp. 121-145
-
-
Ketchum, J.S.1
Sidell, F.R.2
Crowell Jr., E.B.3
Aghajanian, G.K.4
Hayes Jr., A.H.5
-
17
-
-
0022198106
-
Relationship between reversible acetylcholinesterase inhibition and efficacy against soman lethality
-
Lennox WJ, Harris LW, Talbot BG, Anderson DR: Relationship between reversible acetylcholinesterase inhibition and efficacy against soman lethality. Life Sci 1985; 37(9): 793-8.
-
(1985)
Life Sci
, vol.37
, Issue.9
, pp. 793-798
-
-
Lennox, W.J.1
Harris, L.W.2
Talbot, B.G.3
Anderson, D.R.4
-
18
-
-
0003866336
-
-
U.S. Army Medical Research Institute of Chemical Defense , Chemical Casualty Care Division . Aberdeen Proving Ground, MD , USAMRICD
-
U.S. Army Medical Research Institute of Chemical Defense : Medical Management of Chemical Casualties Handbook. Chemical Casualty Care Division . Aberdeen Proving Ground, MD , USAMRICD , 2000
-
(2000)
Medical Management of Chemical Casualties Handbook
-
-
-
19
-
-
33748319204
-
-
Center for Drug Evaluation and Research , Rockville, MD, Food and Drug Administration, Available at, accessed July 15, 2010.
-
Center for Drug Evaluation and Research : Guidance for industry: estimating the maximum safe starting dose in initial clinical trials for therapeutics in adult healthy volunteers. Rockville, MD, Food and Drug Administration, 2005. Available at http://www.fda.gov/downloads/Drugs/ GuidanceComplianceRegulatoryInformation/Guidances/ucm078932. pdf; accessed July 15, 2010.
-
(2005)
Guidance for Industry Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers
-
-
-
20
-
-
33845885861
-
Anticonvulsants for nerve agent-induced seizures: The influence of the therapeutic dose of atropine
-
Shih T-M , Rowland TC , McDonough JH : Anticonvulsants for nerve agent-induced seizures: the influence of the therapeutic dose of atropine. J Pharmacol Exp Ther 2007; 320(1): 154-61.
-
(2007)
J Pharmacol Exp Ther
, vol.320
, Issue.1
, pp. 154-161
-
-
Shih, T.-M.1
Rowland, T.C.2
McDonough, J.H.3
-
22
-
-
0020577156
-
The efficacy of bipyridinium derivatives in the treatment of organophosphonate poisoning in the guinea-pig
-
Inns RH, Leadbeater L: The efficacy of bipyridinium derivatives in the treatment of organophosphonate poisoning in the guinea-pig. J Pharm Pharmacol 1983; 35: 427-33.
-
(1983)
J Pharm Pharmacol
, vol.35
, pp. 427-433
-
-
Inns, R.H.1
Leadbeater, L.2
-
23
-
-
0028132872
-
A review of oximes available for treatment of nerve agent poisoning
-
Dawson RM : A review of oximes available for treatment of nerve agent poisoning. J Appl Toxicol 1994; 14(5): 317-331.
-
(1994)
J Appl Toxicol
, vol.14
, Issue.5
, pp. 317-331
-
-
Dawson, R.M.1
-
24
-
-
0029166587
-
Dose-response effects of atropine and HI-6 treatment of organophosphorus poisoning in guinea pigs
-
Koplovitz I, Menton R, Matthews C, Shutz M, Nalls C, Kelly S: Dose-response effects of atropine and HI-6 treatment of organophosphorus poisoning in guinea pigs. Drug Chem Toxicol 1995; 18(2, 3): 119-36.
-
(1995)
Drug Chem Toxicol
, vol.18
, Issue.2-3
, pp. 119-136
-
-
Koplovitz, I.1
Menton, R.2
Matthews, C.3
Shutz, M.4
Nalls, C.5
Kelly, S.6
-
25
-
-
0026568340
-
Comparison of several oximes against poisoning by soman, tabun and GF
-
Lundy PM , Hansen AS , Hand BT, Boulet CA : Comparison of several oximes against poisoning by soman, tabun and GF. Toxicology 1992; 72: 99-105.
-
(1992)
Toxicology
, vol.72
, pp. 99-105
-
-
Lundy, P.M.1
Hansen, A.S.2
Hand, B.T.3
Boulet, C.A.4
-
26
-
-
0017625733
-
The prophylactic use of 1-methyl,2-hydroxy-iminomethyl-pyridinium methansulfonate (P2S) in the treatment of organophosphate poisoning
-
Gordon JJ , Leadbeater L : The prophylactic use of 1-methyl,2-hydroxy- iminomethyl-pyridinium methansulfonate (P2S) in the treatment of organophosphate poisoning. Toxicol Appl Pharmacol 1977; 40: 109-14.
-
(1977)
Toxicol Appl Pharmacol
, vol.40
, pp. 109-114
-
-
Gordon, J.J.1
Leadbeater, L.2
-
27
-
-
3142597106
-
2-hydroxyiminomethyl-N-methylpyri-dinium methanesulfonate and atropine in the treatment of severe organo-phosphate poisoning
-
Davies DR , Green AL , Wiley GL: 2-hydroxyiminomethyl-N-methylpyri-dinium methanesulfonate and atropine in the treatment of severe organo-phosphate poisoning. Br J Pharmacol 1959; 14: 5-8.
-
(1959)
Br J Pharmacol
, vol.14
, pp. 5-8
-
-
Davies, D.R.1
Green, A.L.2
Wiley, G.L.3
-
28
-
-
84977662815
-
Effect of atropine and diazepam on the efficacy of oxime treatment of nerve agent intoxication
-
Available at, accessed July 15, 2010.
-
Koplovitz I , Schulz SM , Railer RF, Sigler M , Lee RB : Effect of atropine and diazepam on the efficacy of oxime treatment of nerve agent intoxication. J Med Chem Biol Radiol Def 2007; 5. Available at http://www.jmedcbr.org/issue-0501/Koplovitz/Koplovitz-05-07.html; accessed July 15, 2010.
-
(2007)
J Med Chem Biol Radiol Def
, pp. 5
-
-
Koplovitz, I.1
Schulz, S.M.2
Railer, R.F.3
Sigler, M.4
Lee, R.B.5
-
29
-
-
2442702807
-
The role of oximes in the management of organophosphorus pesticide poisoning
-
Eyer P : The role of oximes in the management of organophosphorus pesticide poisoning. Toxicol Rev 2003; 22(3): 165-90.
-
(2003)
Toxicol Rev
, vol.22
, Issue.3
, pp. 165-190
-
-
Eyer, P.1
-
30
-
-
0029982550
-
Performance tests
-
Wetherell A : Performance tests . Environ Health Perspect 1996 ; 104 (Suppl 2) :247-73.
-
(1996)
Environ Health Perspect
, vol.104
, Issue.SUPPL. 2
, pp. 247-273
-
-
Wetherell, A.1
-
31
-
-
0348213441
-
Reactivation of organophosphate inhibited acetylcholinesterase activity by a,ffl-bis-(4-hydroxyiminomethylpyridinium) alkanes in vitro
-
Kuca K, Patocka J, Cabal J: Reactivation of organophosphate inhibited acetylcholinesterase activity by a,ffl-bis-(4-hydroxyiminomethylpyridinium) alkanes in vitro. J Appl Biomed 2003; 1: 207-11.
-
(2003)
J Appl Biomed
, vol.1
, pp. 207-211
-
-
Kuca, K.1
Patocka, J.2
Cabal, J.3
-
32
-
-
33947685552
-
Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinest-erase and butyrylcholinesterase
-
Bartling A , Worek F, Szinicz L , Thiermann H : Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinest-erase and butyrylcholinesterase. Toxicology 2007; 233: 166-72.
-
(2007)
Toxicology
, vol.233
, pp. 166-172
-
-
Bartling, A.1
Worek, F.2
Szinicz, L.3
Thiermann, H.4
-
33
-
-
35448978808
-
An in vitro comparative study on the reactivation of nerve agent-inhibited guinea pig and human acetylcholinesterases by oximes
-
Luo C , Tong M , Nageswararao C , Brecht K , Maxwell DM , Saxena A : An in vitro comparative study on the reactivation of nerve agent-inhibited guinea pig and human acetylcholinesterases by oximes. Biochemistry 2007; 46: 11771-9.
-
(2007)
Biochemistry
, vol.46
, pp. 11771-11779
-
-
Luo, C.1
Tong, M.2
Nageswararao, C.3
Brecht, K.4
Maxwell, D.M.5
Saxena, A.6
|