Using biological markers to inform a clinically meaningful treatment response

Annals of the New York Academy of Sciences

Volumn 1208, Issue 1, 2010, Pages 158-163

  Yehuda, Rachel ^a,b   Bierer, Linda M ^a,b   Pratchett, Laura C ^a   Pelcovitz, Michelle ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Combat trauma; Neuroendocrinology; PTSD; Treatment response

Indexed keywords

BIOLOGICAL MARKER; GLUCOCORTICOID RECEPTOR; PRASTERONE;

ARTICLE; COGNITIVE THERAPY; DISEASE ASSOCIATION; DISEASE SEVERITY; HUMAN; POSTTRAUMATIC STRESS DISORDER; THEORY; TREATMENT RESPONSE; VETERAN; BEHAVIOR THERAPY; METABOLISM; PSYCHOLOGICAL ASPECT; TREATMENT OUTCOME;

BIOLOGICAL MARKERS; DEHYDROEPIANDROSTERONE; HUMANS; IMPLOSIVE THERAPY; RECEPTORS, GLUCOCORTICOID; STRESS DISORDERS, POST-TRAUMATIC; TREATMENT OUTCOME; VETERANS;

EID: 78149259186     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2010.05698.x     Document Type: Article

References (38)

1. Yehuda, R. & L.M. Bierer 2009. The relevance of epigenetics to PTSD: implications for the DSM-V. J. Trauma Stress 22: 427-434.
2. American Psychiatric Association. 2000. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Text Revision: DSM-IV-TR. Washington, DC
3. Kessler, R.C., W.T. Chiu, O. Demler & E.E. Walters 2005. Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Arch. Gen. Psychiatry 62: 617-627.
4. Kessler, R.C. 2000. Posttraumatic stress disorder: the burden to the individual and to society. J. Clin. Psychiatry 61(Suppl. 5): 4-12.
5. The American Legion Benefits Center. February 2, 2010. Disability claims, homelessness top VA list. The American Legion.
6. Eisenman, D., S. Weine, B. Green, et al 2006. The ISTSS/Rand guidelines on mental health training of primary healthcare providers for trauma-exposed populations in conflict-affected countries. J. Trauma Stress 19: 5-17.
7. Bisson, J. & M. Andrew 2007. Psychological treatment of post-traumatic stress disorder (PTSD). Cochrane Database Syst. Rev. 18.
8. Harvey, A.G., R.A. Bryant & N. Tarrier 2003. Cognitive behaviour therapy for posttraumatic stress disorder. Clin. Psychol. Rev. 23: 501-522.
9. Foa, E.B. 2006. Psychosocial therapy for posttraumatic stress disorder. J. Clin. Psychiatry 67: 40-45.
10. Rothbaum, B.O. & A.C. Schwartz 2002. Exposure therapy for posttraumatic stress disorder. Am. J. Psychother. 56: 59-75.
11. Foa, E.B., C.V. Dancu, E.A. Hembree, et al 1999. A comparison of exposure therapy, stress inoculation training, and their combination for reducing posttraumatic stress disorder in female assault victims. J. Consult. Clin. Psych. 67: 194-200.
12. Rothbaum, B.O., M.C. Astin & F. Marsteller 2005. Prolonged exposure versus eye movement desensitization and reprocessing (EMDR) for PTSD rape victims. J. Trauma Stress 18: 607-616.
13. Institute of Medicine's Committee on Treatment of Posttraumatic stress disorder (PTSD). 2007. Treatment of PTSD: an assessment of the evidence. Institute of Medicine of the National Academies.
14. Van Der Kolk, B.A., D. Dreyfuss, M. Michaels, et al 1994. Fluoxetine in posttraumatic stress disorder. J. Clin. Psychiatry 55: 517-522.
15. Zohar, J., D. Amital, C. Miodownik, et al 2002. Double-blind placebo-controlled pilot study of sertraline in military veterans with posttraumatic stress disorder. J. Clin. Psychpharmacol. 22: 190-195.
16. Friedman, M.J., C.R. Marmar, D.G. Baker, et al 2007. Randomized, double-blind comparison of sertraline and placebo for posttraumatic stress disorder in a Department of Veterans Affairs setting. J. Clin. Psychiatry 68: 711-720.
17. Monson, C.M., P.P. Schnurr, P.A. Resick, et al 2006. Cognitive processing therapy for veterans with military-related posttraumatic stress disorder. J. Consult. Clin. Psychol. 74: 898-907.
18. Schnurr, P.P., M.J. Friedman, C.C. Engel, et al Cognitive behavioral therapy for posttraumatic stress disorder in women: a randomized controlled trial. JAMA 297: 820-830.
19. Bradley, R., J. Greene, E. Russ, et al 2005. A multidimensional meta-analysis of psychotherapy for PTSD [published erratum in Am. J. Psychiatry 2005;162:832]. Am. J. Psychiatry 162: 214-227.
20. Schnurr, P.P., M.J. Friedman, C.C. Engel, et al Cognitive behavioral therapy for posttraumatic stress disorder in women: a randomized controlled trial. JAMA 297: 820-830.
21. Fontana, A. & R.A. Rosenheck 1997. Effectiveness and cost of the inpatient treatment of posttraumatic stress disorder: comparison of three models of treatment. Am. J. Psychiatry 154: 758-765.
22. Weathers, F.W., A.M. Ruscio & T.M. Keane 1999. Psychometric properties of nine scoring rules for the Clinician Administered Posttraumatic Stress Disorder Scale. Psychol. Assess. 11: 124-133.
23. Strupp, H.H. & S.W. Hadley 1979. Specific vs nonspecific factors in psychotherapy. A controlled study of outcome. Arch. Gen. Psychiatry 36: 1125-1136.
24. Baker, D.G., S.A. West, W.E. Nicholson, et al 1999. Serial CSF corticotropin-releasing hormone levels and adrenocortical activity in combat veterans with posttraumatic stress disorder [published erratum appears in Am. J. Psychiatry 1999: 156; 986]. Am. J. Psychiatry 156: 585-588.
25. Bremner, J.D., J. Licinio, A. Darnell, et al 1997. Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. Am. J. Psychiatry 154: 624-629.
26. Yehuda, R. 2002. Current status of cortisol findings in post-traumatic stress disorder. Psychiatr. Clin. North Am. 25: 341-368.
27. Bremner, J.D., E. Vermetten & M.E. Kelley 2007. Cortisol, dehydroepiandrosterone, and estradiol measured over 24 hours in women with childhood sexual abuse-related posttraumatic stress disorder. J. Nerv. Ment. Dis. 195: 919-927.
28. Vythilingam, M., J.M. Gill, D.A. Luckenbaugh, et al 2010. Low early morning plasma cortisol in posttraumatic stress disorder is associated with co-morbid depression but not with enhanced glucocorticoid feedback inhibition. Psychoneuroendocrinology 35: 442-450.
29. de Kloet, C.S., E. Bermetten, E. Geuze, et al 2006. Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review. J. Psychiatr. Res. 40: 550-567.
30. Yehuda, R. 2002. Current status of cortisol findings in post-traumatic stress disorder. Psychiatr. Clin. North Am. 25: 341-368.
31. Bremner, J.D., E. Vermetten & M.E. Kelley 2007. Cortisol, dehydroepiandrosterone, and estradiol measured over 24 hours in women with childhood sexual abuse-related posttraumatic stress disorder. J. Nerv. Ment. Dis. 195: 919-927.
32. Flory, J.D., R. Yehuda, R. Grossman, et al 2009. Childhood trauma and basal cortisol in people with personality disorders. Compr. Psychiatry 50: 34-37.
33. Yehuda, R. 2009. Status of glucocorticoid alterations in post-traumatic stress disorder. Ann. N.Y. Acad. Sci. 1179: 56-69.
34. Yehuda, R., R.K. Yang, S.L. Guo, et al 2003. Relationship between dexamethasone-inhibited lysozyme activity in peripheral mononuclear leukocytes and the cortisol and glucocorticoid receptor response to dexamethasone. J. Psychiatr. Res. 37: 471-477.
35. Olff, M., G. de Vries, Y. Güzelcan, et al 2007. Changes in cortisol and DHEA plasma levels after psychotherapy for PTSD. Psychoneuroendocrinology 32: 619-626.
36. Yehuda, R., L.M. Bierer, C. Sarapas, et al 2009. Cortisol metabolic predictors of response to psychotherapy for symptoms for PTSD in survivors of the World Trade Center attacks on September 11, 2001. Psychoneuroendocrinology 34: 1304-1313.
37. Yehuda, R., R.K. Yang, S.L. Guo, et al 2003. Relationship between dexamethasone-inhibited lysozyme activity in peripheral mononuclear leukocytes and the cortisol and glucocorticoid receptor response to dexamethasone. J. Psychiatr. Res. 37: 471-477.
38. Morgan, C.A., 3rd, S. Southwick, G. Hazlett, et al 2004. Relationships among plasma dehydroepiandrosterone sulfate and cortisol levels, symptoms of dissociation, and objective performance in humans exposed to acute stress. Arch. Gen. Psychiatry 61: 819-825.