Superoxide dismutase 1 limits renal microvascular remodeling and attenuates arteriole and blood pressure responses to angiotensin II via modulation of nitric oxide bioavailability

Hypertension

Volumn 56, Issue 5, 2010, Pages 907-913

  Carlström, Mattias ^a,b,c   Lai, En Yin ^a,b   Ma, Zufu ^a,d   Steege, Andreas ^f   Patzak, Andreas ^e   Eriksson, Ulf J ^a   Lundberg, Jon O ^c   Wilcox, Christopher S ^b   Persson, A Erik G ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^f UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

afferent arterioles; CuZnSOD; hypertension; ICSOD; kidney; oxidative stress; SOD1; superoxide

Indexed keywords

ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; COPPER ZINC SUPEROXIDE DISMUTASE; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; SUPEROXIDE DISMUTASE; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BIOAVAILABILITY; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; FEMALE; HEART VENTRICLE PRESSURE; HEART VENTRICLE WALL; KIDNEY BLOOD FLOW; MALE; MICROVASCULARIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; VASCULAR RESISTANCE; ANALYSIS OF VARIANCE; ANIMAL; BLOOD PRESSURE; DRUG EFFECT; GENETICS; KIDNEY; METABOLISM; MICROVASCULATURE; OXIDATIVE STRESS; TRANSGENIC MOUSE; VASCULARIZATION;

ANALYSIS OF VARIANCE; ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; KIDNEY; MICE; MICE, TRANSGENIC; MICROVESSELS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE; VASOCONSTRICTOR AGENTS;

EID: 78149250977     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.110.159301     Document Type: Article

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