ARTICLE;
CELL ASSAY;
CONCENTRATION RESPONSE;
DRUG ACTIVITY;
DRUG ISOLATION;
DRUG POTENCY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
MICROTUBULE;
PHARMACOPHORE;
SPONGE (PORIFERA);
STRUCTURE ACTIVITY RELATION;
SUBSTITUTION REACTION;
Heterocyclic Alkaloids Isolated from the Marine Sponge Pseudoceratina sp. Collected in Papua New Guinea
Manzo, E.; van Soest, R.; Matainaho, L.; Roberge, M.; Andersen, R. J.; Ceratamines, A; Antimitotic, B Heterocyclic Alkaloids Isolated from the Marine Sponge Pseudoceratina sp. Collected in Papua New Guinea Org. Lett. 2003, 5, 4591-4594
Synthesis of the imidazo[4,5-d]azepine ring system
Synthetic compounds containing partially oxidized forms of the ring system were first reported in
Synthetic compounds containing partially oxidized forms of the ring system were first reported in Waly, M. A. Synthesis of the imidazo[4,5-d]azepine ring system Prakt. Chem. 1994, 336, 86-88
Synthesis of antimitotic analogs of the microtubule stabilizing sponge alkaloid ceratamine A
Nodwell, M.; Riffell, J. L.; Roberge, M.; Andersen, R. J. Synthesis of antimitotic analogs of the microtubule stabilizing sponge alkaloid ceratamine A Org. Lett. 2008, 10, 1051-1054
Synthetic approaches to the microtubule-stabilizing sponge alkaloid ceratamine A and desbromo analogues
Nodwell, M; Pereira, A.; Riffell, C.; Zimmerman, C.; Patrick, B. O.; Roberge, M.; Andersen, R. J. Synthetic approaches to the microtubule-stabilizing sponge alkaloid ceratamine A and desbromo analogues J. Org. Chem. 2009, 74, 995-1006
(Z)-α-Haloacrylates: An exceptionally stereoselective preparation via Cr(II)-mediated olefination of aldehydes with trihaloacetates
Barma, D. K.; Kundu, A.; Zhang, H.; Mioskowski, C.; Falck, J. R. (Z)-α-Haloacrylates: an exceptionally stereoselective preparation via Cr(II)-mediated olefination of aldehydes with trihaloacetates J. Am. Chem. Soc. 2003, 125, 3218-3219
Copper-Catalyzed Coupling of Amides and Carbamates with Vinyl Halides
Jiang, L.; Job, G. E.; Klapars, A.; Buchwald, S. L. Copper-Catalyzed Coupling of Amides and Carbamates with Vinyl Halides Org. Lett. 2003, 5, 3667-3669
Expanding Pd-catalyzed C-N bond-forming processes: The first amidation of aryl sulfonates, aqueous amination, and complementarity with Cu-catalyzed reactions
Huang, X.; Anderson, K. W.; Zim, D.; Jiang, L.; Klapars, A.; Buchwald, S. L. Expanding Pd-catalyzed C-N bond-forming processes: The first amidation of aryl sulfonates, aqueous amination, and complementarity with Cu-catalyzed reactions J. Am. Chem. Soc. 2003, 125, 6653-6655
Highly efficient monophosphine-based catalyst for the palladium-catalyzed Suzuki-Miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters
Billingsley, K.; Buchwald, S. L. Highly efficient monophosphine-based catalyst for the palladium-catalyzed Suzuki-Miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters J. Am. Chem. Soc. 2007, 129, 3358-3366
A direct and efficient total synthesis of the tubulin-binding agents ceratamines A and B; Use of IBX for a remarkable heterocyclic dehydrogenation
Coleman, R. S.; Campbell, E. L.; Carper, D. J. A direct and efficient total synthesis of the tubulin-binding agents ceratamines A and B; use of IBX for a remarkable heterocyclic dehydrogenation Org. Lett. 2009, 11, 2133-2136
Andersen, R. J.; Li, D.; Nodwell, M.; Roberge, M.; Strangman, W.; Williams, D. E. Marine natural products that target microtubules. In Handbook of Marine Natural Products; Fattorusso, E.; Gerwick, W.; Taglialatela-Scafati, O., Eds.; Springer: London, 2010; in press.
Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint
Rieder, C. L.; Maiato, H. Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint Dev. Cell 2004, 7, 637-651
Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation
Riffell, J. L.; Zimmerman, C.; Khong, A.; McHardy, L. M.; Roberge, M. Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation Cell Cycle 2009, 8, 1-14
Cell-based screen for antimitotic agents and identification of analogues of rhizoxin, eleutherobin, and paclitaxel in natural extracts
Roberge, M.; Cinel, B.; Anderson, H. J.; Lim, L.; Jiang, X.; Xu, L.; Bigg, C. M.; Kelly, M. T.; Andersen, R. J. Cell-based screen for antimitotic agents and identification of analogues of rhizoxin, eleutherobin, and paclitaxel in natural extracts Cancer Res. 2000, 60, 5052-5058
