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Volumn 32, Issue 1, 2010, Pages 43-62

Systems biology and the mechanistic framework

Author keywords

Design explanation; Functional constraints; Mechanism; Systems biology

Indexed keywords

ANIMAL; ARTICLE; BREATHING; CHEMOTAXIS; ENGINEERING; EVOLUTION; FISH; HUMAN; PHILOSOPHY; PHYSIOLOGY; RESEARCH; SYSTEMS BIOLOGY; THEORETICAL MODEL;

EID: 78049446324     PISSN: 03919714     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (37)

References (32)
  • 2
    • 0033552946 scopus 로고    scopus 로고
    • Robustness in bacterial chemotaxis
    • Alon U. et al., 1999, "Robustness in Bacterial Chemotaxis", Nature, 397: 168-171.
    • (1999) Nature , vol.397 , pp. 168-171
    • Alon, U.1
  • 3
    • 4344715809 scopus 로고    scopus 로고
    • Comment on 'network motifs: Simple building blocks of complex network
    • Artzy-Randrup Y. et al., 2004, "Comment on 'Network Motifs: Simple Building Blocks of Complex Network'" , Science, 305: 1107c
    • (2004) Science , vol.305 , pp. 1107
    • Artzy-Randrup, Y.1
  • 4
    • 0038483826 scopus 로고    scopus 로고
    • Emergence of scaling in random networks
    • Barabasi A.L. and Albert R., 1999, "Emergence of Scaling in Random Networks", Science, 286: 509-512.
    • (1999) Science , vol.286 , pp. 509-512
    • Barabasi, A.L.1    Albert, R.2
  • 5
    • 0030797355 scopus 로고    scopus 로고
    • Robustness in simple biomedical networks
    • Barkai N., Leibler S., 1997, "Robustness in Simple Biomedical Networks", Nature, 387: 913-917.
    • (1997) Nature , vol.387 , pp. 913-917
    • Barkai, N.1    Leibler, S.2
  • 7
    • 38949172760 scopus 로고    scopus 로고
    • Biochemical mechanisms: Organized to mainta in autonomy
    • Boogerd F., Bruggeman F.J., Hofmeyr J.-H.F., Westerhoff H.V. (eds)Amsterdam:Elsevier
    • Bechtel W., 2007, "Biochemical Mechanisms: Organized to Maintain Autonomy". In: Boogerd F., Bruggeman F.J., Hofmeyr J.-H.F., Westerhoff H.V. (eds), Systems Biology, Philosophical Foundations, Amsterdam: Elsevier, 270-302.
    • (2007) Systems Biology, Philosophical Foundations , pp. 270-302
    • Bechtel, W.1
  • 9
    • 0031455398 scopus 로고    scopus 로고
    • The two-component signaling pathway of bacterial chemotaxis
    • Falke J.J. et al., 1997, "The Two-component Signaling Pathway of Bacterial Chemotaxis", Annual Review of Cell and Developmental Biology, 13: 457-512.
    • (1997) Annual Review of Cell and Developmental Biology , vol.13 , pp. 457-512
    • Falke, J.J.1
  • 10
    • 0013112994 scopus 로고    scopus 로고
    • Rethinking mechanistic explanation
    • Glennan S., 2002, "Rethinking Mechanistic Explanation", Philosophy of Science, 69 (Suppl.): S342-S353.
    • (2002) Philosophy of Science , vol.69 , Issue.SUPPL.
    • Glennan, S.1
  • 12
    • 7644238181 scopus 로고    scopus 로고
    • Biological robustness
    • Kitano H., 2005, "Biological Robustness", Nature Review Genetics, 5: 826-837.
    • (2005) Nature Review Genetics , vol.5 , pp. 826-837
    • Kitano, H.1
  • 14
    • 0008311338 scopus 로고    scopus 로고
    • Function and functionalism: A synthetic perspective
    • Mahner M., Bunge M., 2001, "Function and Functionalism: A Synthetic Perspective", Philosophy of Science, 68: 75-94.
    • (2001) Philosophy of Science , vol.68 , pp. 75-94
    • Mahner, M.1    Bunge, M.2
  • 15
    • 85163169203 scopus 로고
    • Developmental constraints and evolution
    • Maynard Smith J. et al., 1985, "Developmental Constraints and Evolution", Quarterly Review of Biology, 60: 265-287.
    • (1985) Quarterly Review of Biology , vol.60 , pp. 265-287
    • Maynard Smith, J.1
  • 17
    • 13444278821 scopus 로고    scopus 로고
    • Reconstruction of cellular signalling networks and analysis of their properties
    • Papin J.A. et al., 2005, "Reconstruction of Cellular Signalling Networks and Analysis of Their Properties", Nature Reviews Molecular Cell Biology, 6: 99-111.
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , pp. 99-111
    • Papin, J.A.1
  • 18
    • 19344376625 scopus 로고    scopus 로고
    • Design and diversity in bacterial chemotaxis: A comparative study in escherichia coli and bacillus subtilis
    • Rao C.V., Kirby J.R., Arkin A.P., 2004, "Design and Diversity in Bacterial Chemotaxis: A Comparative Study in Escherichia coli and Bacillus subtilis", PLOS Biology, 2: 0239-0252.
    • (2004) PLOS Biology , vol.2 , pp. 0239-0252
    • Rao, C.V.1    Kirby, J.R.2    Arkin, A.P.3
  • 22
    • 0010091518 scopus 로고
    • Why ask 'why?' An inquiry concerning scientific explanation
    • Reidel: Dordrecht,Salmon W. (ed.)
    • Salmon W., 1978, "Why Ask 'Why?' An Inquiry Concerning Scientific Explanation".In: Salmon W. (ed.), Hans Reichenbach: Logical Empiricist, Reidel: Dordrecht.
    • (1978) Hans Reichenbach: Logical Empiricist
    • Salmon, W.1
  • 23
    • 68949143071 scopus 로고    scopus 로고
    • Functional and developmental constraints on life-cycle evolution: An attempt on the architecture of constraints
    • Sansom R., Brandon R.N. (eds)Cambridge, MA: The,MIT Press
    • Schlosser G., 2007, "Functional and Developmental Constraints on Life-Cycle Evolution: An Attempt on the Architecture of Constraints". In: Sansom R., Brandon R.N. (eds), Integrating Evolution and Development, Cambridge, MA: The MIT Press.
    • (2007) Integrating Evolution and Development
    • Schlosser, G.1
  • 24
    • 0006706926 scopus 로고
    • Equilibrium explanation
    • Sober E., 1983, "Equilibrium Explanation", Philosophical Studies, 43: 201-210.
    • (1983) Philosophical Studies , vol.43 , pp. 201-210
    • Sober, E.1
  • 26
    • 23844519964 scopus 로고    scopus 로고
    • Circuit topology and the evolution of robustness in two-gene circadian oscillators
    • Wagner A., 2005, "Circuit Topology and the Evolution of Robustness in Two-gene Circadian Oscillators", Proceedings of the National Academy of Sciences, 105: 11775-11780.
    • (2005) Proceedings of the National Academy of Sciences , vol.105 , pp. 11775-11780
    • Wagner, A.1
  • 27
    • 0030932272 scopus 로고    scopus 로고
    • A general model for the origin of allometric scaling laws in biology
    • West G.B., Brown J.H., Enquist J.E., 1997, "A General Model for the Origin of Allometric Scaling Laws in Biology", Science, 276: 122-126.
    • (1997) Science , vol.276 , pp. 122-126
    • West, G.B.1    Brown, J.H.2    Enquist, J.E.3
  • 29
    • 37549072419 scopus 로고    scopus 로고
    • On building a reliable picture with unreliable data: An evolutionary and developmental coda for the new systems biology?
    • Boogerd F., Bruggeman F.J., Hofmeyr J.-H.F., Westerhoff H.V. (eds),Amsterdam:Elsevier
    • Wimsatt W.C., 2007, "On Building a Reliable Picture with Unreliable Data: an Evolutionary and Developmental Coda for the New Systems Biology?". In: Boogerd F., Bruggeman F.J., Hofmeyr J.-H.F., Westerhoff H.V. (eds), Systems Biology, Philosophical Foundations, Amsterdam: Elsevier, 103-120.
    • (2007) Systems Biology, Philosophical Foundations , pp. 103-120
    • Wimsatt, W.C.1
  • 31
    • 34249660479 scopus 로고    scopus 로고
    • Design explanation: Determining the constraints on what can be alive
    • Wouters A., 2007, "Design Explanation: Determining the Constraints on What Can Be Alive", Erkenntnis, 67: 65-80.
    • (2007) Erkenntnis , vol.67 , pp. 65-80
    • Wouters, A.1
  • 32
    • 0034712843 scopus 로고    scopus 로고
    • Robust perfect adaptation in bacterial chemotaxis through integral feedback control
    • Yi T.M. et al., 2000, "Robust Perfect Adaptation in Bacterial Chemotaxis Through Integral Feedback Control", Proceedings of the National Academy of Sciences, 97: 4649-4653.
    • (2000) Proceedings of the National Academy of Sciences , vol.97 , pp. 4649-4653
    • Yi, T.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.