High-resolution structure of the nitrile reductase QueF combined with molecular simulations provide insight into enzyme mechanism

Journal of Molecular Biology

Volumn 404, Issue 1, 2010, Pages 127-137

  Kim, Youngchang ^a   Zhou, Min ^a   Moy, Shiu ^a   Morales, Jennifer ^b   Cunningham, Mark A ^b   Joachimiak, Andrzej ^a  

^a ARGONNE NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF TEXAS PAN AMERICAN   (United States)

Author keywords

Nitrile reduction; Oxidoreductase; QueF; Queuosine

Indexed keywords

7 CYANO 7 DEAZAGUANINE REDUCTASE; ASPARTIC ACID; BACTERIAL ENZYME; CYSTEINE; DIMER; FERREDOXIN; GUANINE DERIVATIVE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HISTIDINE; LIGAND; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL BOND; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTON TRANSPORT; REDUCTION; SIMULATION; VIBRIO CHOLERAE;

VIBRIO CHOLERAE;

EID: 78049445153     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.09.042     Document Type: Article

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