Induction of CYP2B6 and CYP3A4 expression by 1-aminobenzotriazole (ABT) in human hepatocytes

Drug Metabolism Letters

Volumn 4, Issue 3, 2010, Pages 129-133

  Yang, Kyunghee ^a   Koh, Kwi Hye ^a   Jeong, Hyunyoung ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

1 aminobenzotriazole; CAR; CYP induction; CYP2B6; CYP3A4

Indexed keywords

1 AMINOBENZOTRIAZOLE; CELL NUCLEUS RECEPTOR; CYTOCHROME P450 2B6; CYTOCHROME P450 3A4; LUCIFERASE; MESSENGER RNA; RIFAMPICIN; 1-AMINOBENZOTRIAZOLE; 6 (4 CHLOROPHENYL)IMIDAZO(2,1 B)(1,3)THIAZOLE 5 CARBALDEHYDE O (3,4 DICHLOROBENZYL)OXIME; 6-(4-CHLOROPHENYL)IMIDAZO(2,1-B)(1,3)THIAZOLE-5-CARBALDEHYDE O-(3,4-DICHLOROBENZYL)OXIME; CELL RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450 3A; N DEMETHYLASE; OXIME; S MEPHENYTOIN N DEMETHYLASE; S-MEPHENYTOIN N-DEMETHYLASE; THIAZOLE DERIVATIVE; TRIAZOLE DERIVATIVE; UNSPECIFIC MONOOXYGENASE;

ARTICLE; ASSAY; CELL ISOLATION; CONCENTRATION (PARAMETERS); HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; BIOSYNTHESIS; CELL STRAIN HEPG2; DOSE RESPONSE; DRUG EFFECT; ENZYME INDUCTION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; PROMOTER REGION; TRANSCRIPTION INITIATION;

ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP3A; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEP G2 CELLS; HEPATOCYTES; HUMANS; OXIDOREDUCTASES, N-DEMETHYLATING; OXIMES; PROMOTER REGIONS, GENETIC; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RIFAMPIN; RNA, MESSENGER; THIAZOLES; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TRIAZOLES;

EID: 78049427090     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231210791698410     Document Type: Article

References (12)

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