Efficient ring-closing metathesis of alkenyl bromides: The importance of protecting the catalyst during the olefin approach

Journal of the American Chemical Society

Volumn 132, Issue 43, 2010, Pages 15179-15181

  Gatti, Michele ^a   Drinkel, Emma ^a   Wu, Linglin ^a   Pusterla, Ivano ^a   Gaggia, Fiona ^a   Dorta, Reto ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENYL; BROMOALKENE; RING CLOSING METATHESIS; RING-CLOSING METATHESIS REACTIONS;

BROMINE COMPOUNDS; OLEFINS;

CATALYSTS;

ALKENE DERIVATIVE; ALKENYL GROUP; ALKENYLBROMIDE; ALKENYLCHLORIDE; ALKENYLHALIDE; BROMOALKENE; HETEROCYCLIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; RING CLOSING METATHESIS; STOICHIOMETRY; SUBSTITUTION REACTION; SYNTHESIS;

ALKENES; BROMINE; CATALYSIS; HALOGENATION;

EID: 78049403874     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja108253f     Document Type: Article

References (41)

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35. Screening of reaction conditions (solvents, precatalysts etc.) can be found in the Supporting Information.
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41. While compound 6 did not show any apparent reactivity, substrates 20 and 21 partially decomposed with concomitant formation of trace amounts of product (< 10%). A detailed investigation on catalyst and substrate decomposition pathways is underway.