Highly sensitive multiplexed heavy metal detection using quantum-dot-labeled DNAzymes

ACS Nano

Volumn 4, Issue 10, 2010, Pages 5897-5904

  Wu, Chung Shieh ^a,b   Khaing Oo, Maung Kyaw ^a   Fan, Xudong ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

FRET; heavy metal; quantum dot; sensor

Indexed keywords

DETECTION LIMITS; DNAZYME; DYE MOLECULE; EFFICIENT ENERGY TRANSFER; EXCITATION SOURCES; FRET; HEAVY METAL DETECTION; HIGHLY SENSITIVE; MULTIPLEXED DETECTION; QUANTUM DOT; QUANTUM DOTS; SILICA LAYERS; SINGLE LASERS; SMALL SIZE;

DNA; ENERGY TRANSFER; HEAVY METALS; LASER EXCITATION; METAL IONS; METALS; MULTIPLEXING; NANOSENSORS; OPTICAL WAVEGUIDES; QUANTUM YIELD; SILICA;

SEMICONDUCTOR QUANTUM DOTS;

COPPER; DEOXYRIBOZYME; HEAVY METAL; ION; LEAD; METAL; OLIGONUCLEOTIDE; QUANTUM DOT;

ARTICLE; CHEMISTRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC PROCEDURES; HUMAN; METHODOLOGY; MOLECULAR GENETICS; NANOTECHNOLOGY; NUCLEOTIDE SEQUENCE; REPRODUCIBILITY; SPECTROFLUOROMETRY;

BASE SEQUENCE; BIOSENSING TECHNIQUES; COPPER; DNA, CATALYTIC; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; IONS; LEAD; METALS; METALS, HEAVY; MOLECULAR SEQUENCE DATA; NANOTECHNOLOGY; OLIGONUCLEOTIDES; QUANTUM DOTS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, FLUORESCENCE;

EID: 78049331881     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn1021988     Document Type: Article

References (42)

1. Verma, N.; Singh, M. Biosensors for Heavy Metals BioMetals 2005, 18, 121-129
2. Panov, V.; Zykova, I.; Chekrenev, S. Heavy Metals: The Industry and Environmental Protection Fibre Chem. 2008, 40, 241-245
3. Wu, C.-S.; Cupps, J. M.; Fan, X. Compact Quantum Dot Probes for Rapid and Sensitive DNA Detection Using Highly Efficient Fluorescence Resonant Energy Transfer Nanotechnology 2009, 20, 305502
4. Brewer, G. J. Risks of Copper and Iron Toxicity during Aging in Humans Chem. Res. Toxicol. 2010, 23, 319-326
5. Bruins, M. R.; Kapil, S.; Oehme, F. W. Microbial Resistance to Metals in the Environment Ecotoxicol. Environ. Safety 2000, 45, 198-207
6. Todd, M. D.; Lee, M. J.; Williams, J. L.; Nalezny, J. M.; Gee, P.; Benjamin, M. B.; Farr, S. B. The CAT-Tox (L) Assay: A Sensitive and Specific Measure of Stress-Induced Transcription in Transformed Human Liver Cells Fundam. Appl. Toxicol. 1995, 28, 118-128
7. Rogers, J. T.; Richards, J. G.; Wood, C. M. Ionoregulatory Disruption as the Acute Toxic Mechanism for Lead in the Rainbow Trout (Oncorhynchus mykiss) Aquat. Toxicol. 2003, 64, 215-234
8. Miyake, Y.; Togashi, H.; Tashiro, M.; Yamaguchi, H.; Oda, S.; Kudo, M.; Tanaka, Y.; Kondo, Y.; Sawa, R.; Fujimoto, T. et al. MercuryII-Mediated Formation of Thymine-HgII-Thymine Base Pairs in DNA Duplexes J. Am. Chem. Soc. 2006, 128, 2172-2173
9. Kim, H.-K.; Rasnik, I.; Liu, J.; Ha, T.; Lu, Y. Dissecting Metal Ion-Dependent Folding and Catalysis of a Single DNAzyme Nat. Chem. Biol. 2007, 3, 763-768
10. Hussein, H.; Farag, S.; Kandil, K.; Moawad, H. Tolerance and Uptake of Heavy Metals by Pseudomonads Process Biochem. 2005, 40, 955-961
11. Kunkel, R.; Manahan, S. E. Atomic Absorption Analysis of Strong Heavy Metal Chelating Agents in Water and Waste Water Anal. Chem. 1973, 45, 1465-1468
12. Bings, N. H.; Bogaerts, A.; Broekaert, J. A. C. Atomic Spectroscopy Anal. Chem. 2006, 78, 3917-3946
13. Tanyanyiwa, J.; Hauser, P. C. High-Voltage Contactless Conductivity Detection of Metal Ions in Capillary Electrophoresis Electrophoresis 2002, 23, 3781-3786
14. Lorber, K. E. Monitoring of Heavy Metals by Energy Dispersive X-ray Fluorescence Spectrometry Waste Manage. Res. 1986, 4, 3-13
15. Bertsch, P. M.; Hunter, D. B. Applications of Synchrotron-Based X-ray Microprobes Chem. Rev. 2001, 101, 1809-1842
16. Czarnik, A. W. Desperately Seeking Sensors Chem. Biol. 1995, 2, 423-428
17. Lu, Y. New Transition-Metal-Dependent DNAzymes as Efficient Endonucleases and as Selective Metal Biosensors Chem.-Eur. J. 2002, 8, 4588-4596
18. Liu, J.; Cao, Z.; Lu, Y. Functional Nucleic Acid Sensors Chem. Rev. 2009, 109, 1948-1998
19. Liu, J.; Lu, Y. Improving Fluorescent DNAzyme Biosensors by Combining Inter- and Intramolecular Quenchers Anal. Chem. 2003, 75, 6666-6672
20. 2+ Ions in Aqueous Solution with High Sensitivity and Selectivity J. Am. Chem. Soc. 2007, 129, 9838-9839
21. Liu, J.; Brown, A. K.; Meng, X.; Cropek, D. M.; Istok, J. D.; Watson, D. B.; Lu, Y. A Catalytic Beacon Sensor for Uranium with Parts-Per-Trillion Sensitivity and Millionfold Selectivity Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 2056-2061
22. 2+ in Aqueous Solution Based on Structure-Switching DNA Chem. Commun. 2008, 6005-6007
23. Eggeling, C.; Widengren, J.; Rigler, R.; Seidel, C. A. M. Photobleaching of Fluorescent Dyes under Conditions Used for Single-Molecule Detection: Evidence of Two-Step Photolysis Anal. Chem. 1998, 70, 2651-2659
24. Han, M.; Gao, X.; Su, J. Z.; Nie, S. Quantum-Dot-Tagged Microbeads for Multiplexed Optical Coding of Biomolecules Nat. Biotechnol. 2001, 19, 631-635
25. Hohng, S.; Ha, T. Single-Molecule Quantum-Dot Fluorescence Resonance Energy Transfer ChemPhysChem 2005, 6, 956-960
26. Willard, D. M.; Van Orden, A. Quantum Dots: Resonant Energy-Transfer Sensor Nat. Mater. 2003, 2, 575-576
27. Gill, R.; Zayats, M.; Willner, I. Semiconductor Quantum Dots for Bioanalysis Angew. Chem., Int. Ed. 2008, 47, 7602-7625
28. Sharon, E.; Freeman, R.; Willner, I. CdSe/ZnS Quantum Dots-G-Quadruplex/Hemin Hybrids as Optical DNA Sensors and Aptasensors Anal. Chem. 2010, 82, 7073-7077
29. Wang, L.-Y.; Wang, L.; Gao, F.; Yu, Z.-Y.; Wu, Z.-M. Application of Functionalized CdS Nanoparticles as Fluorescence Probe in the Determination of Nucleic Acids Analyst 2002, 127, 977-980
30. Chan, W. C. W.; Nie, S. Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection Science 1998, 281, 2016-2018
31. 2+ and Design of Logic Gates by the Application of Supramolecular Constructs of Ion-Dependent DNAzymes Nano Lett. 2009, 9, 1196-1200
32. + Ions by Nucleic Acid Functionalized CdSe/ZnS Quantum Dots and Their Use for Logic Gate Operations Angew. Chem., Int. Ed. 2009, 48, 7818-7821
33. Liang, J.-G.; Ai, X.-P.; He, Z.-K.; Pang, D.-W. Functionalized CdSe Quantum Dots as Selective Silver Ion Chemodosimeter Analyst 2004, 129, 619-622
34. Chen, Y.; Rosenzweig, Z. Luminescent CdS Quantum Dots as Selective Ion Probes Anal. Chem. 2002, 74, 5132-5138
35. 2+ Anal. Chem. 2009, 81, 6252-6257
36. Xia, Y.-S.; Zhu, C.-Q. Use of Surface-Modified CdTe Quantum Dots as Fluorescent Probes in Sensing Mercury(II) Talanta 2008, 75, 215-221
37. Susha, A. S.; Javier, A. M.; Parak, W. J.; Rogach, A. L. Luminescent CdTe Nanocrystals as Ion Probes and pH Sensors in Aqueous Solutions Colloids Surf., A 2006, 281, 40-43
38. Isarov, A. V.; Chrysochoos, J. Optical and Photochemical Properties of Nonstoichiometric Cadmium Sulfide Nanoparticles: Surface Modification with Copper(II) Ions Langmuir 1997, 13, 3142-3149
39. Bruchez, M., Jr.; Moronne, M.; Gin, P.; Weiss, S.; Alivisatos, A. P. Semiconductor Nanocrystals as Fluorescent Biological Labels Science 1998, 281, 2013-2016
40. Gerion, D.; Pinaud, F.; Williams, S. C.; Parak, W. J.; Zanchet, D.; Weiss, S.; Alivisatos, A. P. Synthesis and Properties of Biocompatible Water-Soluble Silica-Coated CdSe/ZnS Semiconductor Quantum Dots J. Phys. Chem. B 2001, 105, 8861-8871
41. Clapp, A. R.; Medintz, I. L.; Mauro, J. M.; Fisher, B. R.; Bawendi, M. G.; Mattoussi, H. Fluorescence Resonance Energy Transfer between Quantum Dot Donors and Dye-Labeled Protein Acceptors J. Am. Chem. Soc. 2004, 126, 301-310
42. Thomas, S.; Herwig, B.; Günter, E. M. T. Controlled Surface Functionalization of Silica Nanospheres by Covalent Conjugation Reactions and Preparation of High Density Streptavidin Nanoparticles J. Nano. Nanotechnol. 2004, 4, 504-511