A gradient-generating microfluidic device for cell biology

Journal of Visualized Experiments

Volumn , Issue 7, 2007, Pages

  Chung, Bong Geun ^a   Manbachi, Amir ^a   Saadi, Wajeeh ^a   Lin, Francis ^a   Jeon, Noo Li ^a   Khademhosseini, Ali ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Cell biology; Cell migration; Gradient; Issue 7; Microfluidic; Tissue engineering

Indexed keywords

EID: 80355127214     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/271     Document Type: Article

References (5)

1. Jeon N.L., Baskaran H., Dertinger S.K.W., Whitesides G.M., Van de Water L., Toner M. Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat. Biotechnol. 20(8), 826-830 (2002)
2. Lin F., Nguyen C.M., Wang S.J., Saadi W., Gross S.P., Jeon N.L. Effective neutrophil chemotaxis is strongly influenced by mean IL-8 concentration. Biochem. Biophys. Res. Commun. 319(2), 576-581. (2004)
3. Chung B.G., Flanagan L.A., Rhee S.W., Schwartz P.H., Lee A.P., Monuki E.S., Jeon N.L. Human neural stem cell growth and differentiation in a gradient-generating microfluidic device. Lab Chip 5(4), 401-406 (2005)
4. Saadi W., Wang S.J, Lin F., Jeon N.L. A parallel-gradient microfluidic chamber for quantitative analysis of breast cancer cell chemotaxis. Biomed. Microdevices 8(2), 109-118 (2007)
5. Chung B.G., Park J.W., Hu J.S., Huang C., Monuki E.S., Jeon N.L. A hybrid microfluidic-vacuum device for interfacing with conventional cell culture platform. BMC Biotechnol., 7(1), 60 (2007)