Lancemaside A inhibits lipopolysaccharide-induced inflammation by targeting LPS/TLR4 complex

Journal of Cellular Biochemistry

Volumn 111, Issue 4, 2010, Pages 865-871

  Joh, Eun Ha ^a   Kim, Dong Hyun ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Inflammation; IRAK 4; Lancemaside A; LPS; TLR4

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 1BETA; LANCEMASIDE A; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING COMPETITION; CELL ISOLATION; CODONOPSIS LANCEOLATA; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; THERAPY EFFECT;

ANIMALS; CYCLOOXYGENASE 2; CYTOKINES; I-KAPPA B KINASE; I-KAPPA B PROTEINS; INFLAMMATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED ICR; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; SAPONINS; TOLL-LIKE RECEPTOR 4;

CAMPANULACEAE; CODONOPSIS LANCEOLATA; MUS;

EID: 78049300969     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22773     Document Type: Article

References (38)

1. Ahn KS, Hahn BS, Kwack K, Lee EB, Kim YS. 2006. Platycodin D-induced apoptosis through nuclear factor-kappaB activation in immortalized keratinocytes. Eur J Pharmacol 537: 1-11.
2. Astiz ME, Rackow EC. 1998. Septic shock. Lancet 351: 1501-1505.
3. Bakker AD, Silva VC, Krishnan R, Bacabac RG, Blaauboer ME, Lin YC, Marcantonio RA, Cirelli JA, Klein-Nulend J. 2009. Tumor necrosis factor alpha and interleukin-1beta modulate calcium and nitric oxide signaling in mechanically stimulated osteocytes. Arthritis Rheum 60: 3336-3345.
4. Baldwin AS, Jr. 1996. The NF-κB and IκB proteins: New discoveries and insights. Annu Rev Immunol 14: 649-681.
5. Baldwin AS, Jr. 2001. Series introduction: The transcription factor NF-kappaB and human disease. J Clin Invest 107: 3-6.
6. Blanque R, Meakin C, Millet S, Gardner CR. 1996. Hypothermia as an indicator of the acute effects of lipopolysaccharides: Comparison with serum levels of IL1 beta, IL6 and TNF alpha. Gen Pharmacol 27: 973-977.
7. Cario E, Pldolsky DK. 2000. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun 68: 7010-7017.
8. Chan MM, Huang HI, Fenton MR, Fong D. 1998. In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties. Biochem Pharmacol 55: 1955-1962.
9. Chen YH, Lin SJ, Ku HH, Shiao MS, Lin FY, Chen JW, Chen YL. 2001. Salvianolic acid B attenuates VCAM-1 and ICAM-1 expression in TNF-alpha-treated human aortic endothelial cells. J Cell Biochem 82: 512-521.
10. Chung JW, Noh EJ, Zhao HL, Sim JS, Ha YW, Shin EM, Lee EB, Cheong CS, Kim YS. 2008. Anti-inflammatory activity of prosapogenin methyl ester of platycodin D via nuclear factor-kappaB pathway inhibition. Biol Pharm Bull 31: 2114-2120.
11. Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. 1995. Transcriptional regulation of endothelial cell adhesion molecules: NF-κB and cytokine inducible enhancers. FASEB J 9: 899-909.
12. Davis PA, Polagruto JA, Valacchi G, Phung A, Soucek K, Keen CL, Gershwin ME. 2006. Effects of apple extracts on NF-κB activation of human umbilical vein endothelial cells. Exp Biol Med (Maywood) 231: 594-598.
13. Fairweather D, Rose NR. 2005. Inflammatory heart disease: A role for cytokines. Lupus 14: 646-651.
14. Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, Takeda K, Akira S. 1999. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product. J Immunol 162: 3749-3752.
15. Huang YT, Hwang JJ, Lee PP, Ke FC, Huang JH, Huang CJ, Kandaswami C, Middleton E, Jr., Lee MT. 1999. Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor. Br J Pharmacol 128: 999-1010.
16. Joh EH, Lee IA, Han SJ, Chae S, Kim DH. 2010. Lancemaside A ameliorates colitis by inhibiting NF-kappaB activation in TNBS-induced colitis mice. Int J Colorectal Dis 25: 545-551.
17. Kim SY, Kim DH, Han SJ, Hyun JW, Kim HS. 2007. Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells. Biochem Pharmacol 74: 1642-1651.
18. Kotanidou A, Xagorari A, Bagli E, Kitsanta P, Fotsis T, Papapetropoulos A, Roussos C. 2002. Luteolin reduces lipopolysaccharide-induced lethal toxicity and expression of proinflammatory molecules in mice. Am J Respir Crit Care Med 165: 818-823.
19. Kwon KH, Murakami A, Tanaka T, Ohigashi H. 2005. Dietary rutin but not its aglycone quercetin, ameliorates dextran sulfate sodium-induced experimental colitis in mice: Attenuation of pro-inflammatory gene expression. Biochem Pharmacol 69: 395-406.
20. Lee KT, Choi J, Jung WT, Nam JH, Jung HJ, Park HJ. 2002. Structure of a new echinocystic acid bisdesmoside isolated from Codonopsis lanceolata roots and the cytotoxic activity of prosapogenins. J Agric Food Chem 50: 4190-4193.
21. Li S, Strelow A, Fontana EJ, Wesche H. 2002. IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase. Proc Natl Acad Sci USA 99: 5567-5572.
22. Libby P. 2006. Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr 83: 456S-460S.
23. Lin WW, Karin M. 2007. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117: 1175-1183.
24. Lu WQ, Qiu Y, Li TJ, Tao X, Sun LN, Chen WS. 2009. Timosaponin B-II inhibits pro-inflammatory cytokine induction by lipopolysaccharide in BV2 cells. Arch Pharm Res 32: 1301-1308.
25. Moynagh PN. 2005. The NF-kappaB pathway. J Cell Sci 118: 4589-4592.
26. O'keefe JH, Gheewala NM, O'keefe JO. 2008. Dietary strategies for improving post-prandial glucose, lipids, inflammation, and cardiovascular health. J Am Coll Cardiol 51: 249-255.
27. Paradkar PN, Blum PS, Berhow MA, Baumann H, Kuo SM. 2004. Dietary isoflavones suppress endotoxin-induced inflammatory reaction in liver and intestine. Cancer Lett 215: 21-28.
28. Park EK, Shin YW, Lee HU, Kim SS, Lee YC, Lee BY, Kim DH. 2005. Inhibitory effect of ginsenoside Rb1 and compound K on NO and prostaglandin E2 biosyntheses of RAW264.7 cells induced by lipopolysaccharide. Biol Pharm Bull 28: 652-656.
29. Park YJ, Liu G, Lorne EF, Zhao X, Wang J, Tsuruta Y, Zmijewski J, Abraham E. 2008. PAI-1 inhibits neutrophil efferocytosis. Proc Natl Acad Sci USA 105: 11784-11789.
30. Park YJ, Liu G, Tsuruta Y, Lorne E, Abraham E. 2009. Participation of the urokinase receptor in neutrophil efferocytosis. Blood 114: 860-870.
31. Schottenfeld D, Beebe-Dimmer J. 2006. Chronic inflammation-a common and important factor in the pathogenesis of neoplasia. CA Cancer J Clin 56: 69-83.
32. Shin YW, Kim DH. 2005. Antipruritic effect of ginsenoside rb1 and compound k in scratching behavior mouse models. J Pharmacol Sci 99: 83-88.
33. Shin YW, Bae EA, Kim SS, Lee YC, Kim DH. 2005. Effect of ginsenoside Rb1 and compound K in chronic oxazolone-induced mouse dermatitis. Int Immunopharmacol 5: 1183-1191.
34. Shoelson SE, Herrero L, Naaz A. 2007. Obesity, inflammation, and insulin resistance. Gastroenterology 132: 2169-2180.
35. Tak PP, Firestein GS. 2001. NF-kappaB: A key role in inflammatory diseases. J Clin Invest 107: 7-11.
36. Tousoulis D, Charakida M, Stefanadis C. 2005. Endothelial function and inflammation in coronary artery disease. Heart 92: 441-444.
37. Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ. 2001. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412: 346-351.
38. Yaraee R, Ghazanfari T, Ebtekar M, Ardestani SK, Rezaei A, Kariminia A, Faghihzadeh S, Mostafaie A, Vaez-Mahdavi MR, Mahmoudi M, Naghizadeh MM, Soroush MR, Hassan ZM. 2009. Alterations in serum levels of inflammatory cytokines (TNF, IL-1alpha, IL-1beta and IL-1Ra) 20 years after sulfur mustard exposure: Sardasht-Iran cohort study. Int Immunopharmacol 9: 1466-1470.