In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationships

Journal of Antibiotics

Volumn 63, Issue 10, 2010, Pages 619-622

  Iwatsuki, Masato ^a   Otoguro, Kazuhiko ^a   Ishiyama, Aki ^a   Namatame, Miyuki ^a   Nishihara Tukashima, Aki ^a   Hashida, Junko ^a   Nakashima, Takuji ^a   Masuma, Rokuro ^a   Takahashi, Yoko ^a   Yamada, Haruki ^a   Ömura, Satoshi ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Antitrypanosomal; low molecular weight antibiotics; structure activity relationships

Indexed keywords

8 CHLORO 3',4',5,7 TETRAHYDROXYISOFLAVONE; ANDRASTIN A; ANTIBIOTIC AGENT; ANTITRYPANOSOMAL AGENT; EFLORNITHINE; GLIOTOXIN; GLIOVIRIN; ISOCHROMOPHILONE I; LANKACIDIN A; OCHREPHILONE; OKILACTOMYCIN; PILOQUINONE; SF 2583 A; SF 2583 B; SURAMIN; THIOLUTIN; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ANTITRYPANOSOMAL ACTIVITY; ARTICLE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA BRUCEI;

ANTI-BACTERIAL AGENTS; CELL LINE; DRUG DESIGN; HUMANS; MOLECULAR WEIGHT; PARASITIC SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

EID: 78049283272     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2010.99     Document Type: Article

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