Sustained levels of progesterone prior to the onset of cerebral ischemia are not beneficial to female mice

Brain Research

Volumn 1361, Issue , 2010, Pages 124-132

  Coomber, Ben ^a   Gibson, Claire L ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Aquaporins; Cerebral edema; Focal cerebral ischemia; Progesterone; Stroke

Indexed keywords

AQUAPORIN 4; PLACEBO; PROGESTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN WATER; CONTROLLED STUDY; EVALUATION; FEMALE; IMPLANT; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; OVARIECTOMY; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROTEIN EXPRESSION; SHAM PROCEDURE; STATISTICAL SIGNIFICANCE; WATER CONTENT; WELLBEING;

ANIMALS; AQUAPORIN 4; BODY WEIGHT; BRAIN; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; FEMALE; FUNCTIONAL LATERALITY; INFARCTION, MIDDLE CEREBRAL ARTERY; MICE; MICE, INBRED C57BL; OVARIECTOMY; PROGESTERONE; RECOVERY OF FUNCTION; TREATMENT OUTCOME;

ANIMALIA; MUS;

EID: 78049280232     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.09.037     Document Type: Article

References (51)

1. N.J. Alkayed, S.J. Murphy, R.J. Traystman, P.D. Hurn, and V.M. Viller Gender-linked brain injury in experimental stroke Stroke 29 1998 159 165
2. N.J. Alkayed, S.J. Murphy, R.J. Traystman, P.D. Hurn, and V.M. Miller Neuroprotective effects of female gonadal steroids in reproductively senescent female rats Stroke 31 2000 161 168
3. J.B. Bederson, L.H. Pitts, S.M. Germano, M.C. Nishimura, R.L. Davis, and H.M. Bartowski Evaluation of 2, 3, 5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats Stroke 17 1986 1304 1308
4. J.B. Bederson, L.H. Pitts, M. Tsuji, M.C. Nishimura, R.L. Davis, and H. Bartowski Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination Stroke 17 1986 472 476
5. J. Chen, M. Chopp, and Y. Li Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat J. Neurol. Sci. 171 1999 24 30
6. G.H. Danton, and W.D. Dietrich Inflammatory mechanisms after ischemia and stroke J. Neuropath. Exp. Neurol. 62 2003 127 136
7. D.B. Dubal, M.L. Kashon, L.C. Pettigrew, J.M. Ren, S.P. Finklestein, S.W. Rau, and P.M. Wise Estradiol protects against ischemic injury J. Cereb. Blood Flow Metab. 18 1998 1253 1258
8. R. Duvdevani, R.L. Roof, Z. Fulop, and D.G. Stein Blood-brain barrier breakdown and edema formation following frontal cortical contusion: does hormonal status play a role? J. Neurotrauma 12 1995 65 75
9. S.A. Farr, J.F. Flood, J.F. Scherrer, F.E. Kaiser, G.T. Taylor, and J.E. Morley Effect of ovarian steroids on footshock avoidance learning and retention in female mice Physiol. Behav. 58 1995 715 723
10. J.G. Fox, S. Barthold, M. Davisson, C.E. Newcomer, F.W. Quimby, and A. Smith The Mouse in Biomedical Research: Normative Biology, Husbandry, and Models: 3 2006 Academic Press London, UK
11. D.S. Frydenlund, A. Bhardwaj, T. Otsuka, M.N. Mylonakou, T. Yasumura, K.G. Davidson, E. Zeynalov, O. Skare, P. Laake, F.M. Haug, J.E. Rash, P. Agre, O.P. Ottersen, and M. Amiry-Moghaddam Temporary loss of perivascular aquaporin-4 in neocortex after transient middle cerebral artery occlusion in mice Proc. Natl. Acad. Sci. U. S. A. 103 2006 1353
12. C.A. Frye, L.E. Bayon, N.K. Pursani, and R.H. Purdy The neurosteroids, progesterone and 3α, 5α-THP enhance sexual motivation, receptivity, and proceptivity in female rats Brain Res. 808 1998 72 83
13. J.M. Gebel, E.C. Jauch, T.G. Brott, J. Khoury, L. Sauerbeck, S. Salisbury, J. Spiker, T.A. Tomsick, J. Duldner, and J.P. Broderick Relative edema volume is a predictor of outcome in patients with hyperacute spontaneous intracerebral hemorrhage Stroke 33 2002 2636 2641
14. C.L. Gibson, and S.P. Murphy Progesterone enhances functional recovery following middle cerebral artery occlusion in male mice J. Cereb. Blood Flow Metab. 24 2004 805 813
15. C.L. Gibson, D. Constantin, M.J.W. Prior, P.M.W. Bath, and S.P. Murphy Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia Exp. Neurol. 193 2005 522 530
16. C.L. Gibson, N.C. Jones, M.J.W. Prior, P.M.W. Bath, and S.P. Murphy G-CSF suppresses edema formation and reduces interleukin-1β expression after cerebral ischemia in mice J. Neuropathol. Exp. Neurol. 64 2005 1 7
17. C.L. Gibson, L.J. Gray, P.M.W. Bath, and S.P. Murphy Progesterone for the treatment of experimental brain injury; a systematic review Brain 131 2008 318 328
18. C.L. Gibson, B. Coomber, and J. Rathbone Is progesterone a candidate neuroprotective factor for treatment following ischemic stroke? Neuroscientist 15 2009 324 332
19. M.D. Gonzalez-Vidal, M. Cervera-Gaviria, R. Ruelas, A. Escobar, G. Morali, and M. Cervantes Progesterone: protective effects on the cat hippocampal neuronal damage due to acute global cerebral ischemia Arch. Med. Res. 1998 1998 117 124
20. K.J. Grossman, and D.G. Stein Does endogenous progesterone promote recovery of chronic sensorimotor deficits following contusion to the forelimb representation of the sensorimotor cortex? Behav. Brain Res. 2000 2000 141 148
21. Q. Guo, I. Sayeed, L.M. Baronne, S.W. Hoffman, R. Guennoun, and D.G. Stein Progesterone administration modulates AQP4 expression and edema after traumatic brain injury in male rats Exp. Neurol. 198 2006 469 478
22. K. Hayakawa, K. Mishima, K. Irie, M. Hazekawa, S. Mishima, M. Fujioka, K. Orito, N. Egashira, S. Katsurabayashi, K. Takasaki, K. Iwasaki, and M. Fujiwara Cannabidiol prevents a post-ischemic injury progressively induced by cerebral ischemia via a high-mobility group box1-inhibiting mechanism Neuropharmacology 55 2008 1280 1286
23. J. He, C.O. Evans, S.W. Hoffman, N.M. Ovesiku, and D.G. Stein Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury Exp. Neurol. 189 2004 404 412
24. P.D. Hurn, and I.M. Macrae Estrogen as a neuroprotectant in stroke J. Cereb. Blood Flow Metab. 20 2000 631 652
25. P.D. Hurn, A.A. Aardelt, N.J. Alkayed, B.J. Crain, W. Hu, M.L. Kearney, L.D. McCullough, S.J. Murphy, T.J.K. Toung, R.J. Traystman, and M. Wang Estrogen and testosterone as neuroprotectants in stroke J. Krieglstein, Pharmacology of Cerebral Ischemia 2002 Medpharm Scientific Publishers Stuttgart 17 24
26. N. Jiang, M. Chopp, D. Stein, and H. Feit Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats Brain Res. 735 1996 101 107
27. A. Korneyev, A. Guidotti, and E. Costa Regional and interspecies differences in brain progesterone metabolism J. Neurochem. 61 1993 2041 2047
28. Y. Kumon, S.C. Kim, P. Tompkins, A. Stevens, S. Sakaki, and C.M. Loftus Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia J. Neurosurg. 92 2000 848 852
29. Y. Liu, W. Zhang, N.J. Alkayed, S.C. Froehner, M.E. Adams, M. Amiry-Moghaddam, O.P. Ottersen, P.D. Hurn, and A. Bhardwaj Lack of sex-linked differences in cerebral edema and aquaporin-4 expression after experimental stroke J. Cereb. Blood Flow Metab. 28 2008 1898 1906
30. E.H. Lo, T. Dalkara, and M.A. Moskowitz Mechanisms, challenges and opportunities in stroke Nat. Rev. Neurosci. 4 2003 399 415
31. A.K. Loihl, V. Asensio, I.L. Campbell, and S.P. Murphy Expression of nitric oxide synthase (NOS)-2 following permanent focal ischemia and the role of nitric oxide in infarct generation in male, female and nos-2 gene-deficient mice Brain Res. 830 1999 155 164
32. G.T. Manley, M. Fujimura, T. Ma, N. Noshita, F. Filiz, A.W. Bollen, P. Chan, and A.S. Verkman Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke Nat. Med. 6 2000 159 163
33. S.J. Murphy, R.J. Traystman, and P.D. Hurn Progesterone exacerbates striatal stroke injury in progesterone-deficient female animals Stroke 31 2000 1173 1178
34. S.J. Murphy, M. Littleton-Kearney, and P.D. Hurn Progesterone administration during reperfusion, but not preischemia alone, reduces injury in ovariectomised rats J. Cereb. Blood Flow Metab. 22 2002 1181 1188
35. S.J. Murphy, L.D. McCullough, and J.M. Smith Stroke in the female: role of biological sex and estrogen ILAR J. 45 2004 147 159
36. S.M. Murr, G.H. Stabenfeldt, G.E. Bradford, and I.I. Geschwind Plasma progesterone during pregnancy in the mouse Endocrinology 94 1974 1209 12111
37. J.E. Rash, T. Yasumura, C.S. Hudson, P. Agre, and S. Nielsen Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord Proc. Natl. Acad. Sci. U. S. A. 95 1998 11981 11986
38. D.C. Rogers, C.A. Campbell, J.L. Stretton, and K.B. Mackay Correlation between motor impairment and infarct volume after permanent and transient middle cerebral artery occlusion in the rat Stroke 28 1997 2060 2066
39. R.L. Roof, and D.G.S. Hoffman Progesterone protects against lipid peroxidation following traumatic brain injury in rats Mol. Chem. Neuropathol. 31 1997 1 11
40. R.L. Roof, R. Duvdevani, and D.G. Stein Progesterone treatment attenuates brain edema following contusion injury in male and female rats Restor. Neurol. Neurosci. 4 1993 425 427
41. R. Rusa, N.J. Alkayed, R.J. Traystman, J.A. Klaus, A.S. Kimes, E.D. London, B.J. Crain, and P.D. Hurn Estrogen replacement therapy is neuroprotective in experimental stroke Stroke 30 1999 1665 1670
42. T.R. Saito, T. Kosaka, and K.W. Takahashi Plasma progesterone levels in pseudopregnant mice Jpn. J. Vet. Sci. 44 1982 125 126
43. J.W. Simpkins, G. Rajakumar, Y.Q. Zhang, C.E. Simpkins, D. Greenwald, C.J. Yu, N. Bodor, and A.L. Day Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat J. Neurosurg. 87 1997 724 730
44. S.S. Smith Female sex steroid hormones: from receptors to networks to performance - actions on the sensorimotor system Prog. Neurobiol. 44 1994 55 86
45. T.J. Toung, P.D. Hurn, R.J. Traystman, and F.E. Sieber Estrogen decreases infarct size after temporary focal ischaemia in a genetic model of type I diabetes mellitus Stroke 31 2000 2701 2706
46. L.C. Turtzo, and L.D. McCullough Sex differences in stroke Cerebrovasc. Dis. 26 2008 462 474
47. S. Wassertheil-Smoller, S.L. Hendrix, M. Limacher, G. Heiss, C. Kooperberg, A. Baird, T. Kotchen, J.D. Curb, H. Black, J.E. Rossouw, A. Aragaki, M. Safford, E. Stein, S. Laowattana, W.J. Mysiw, and W.H.I. Investigators Effect of estrogen plus progestin on stroke in post-menopausal women-the Women's Health Initiative: a randomized trial JAMA 289 2003 2673 2674
48. P.M. Wise, D.B. Dubal, M.E. Wilson, S.W. Rau, M. Bottner, and K.L. Rosewell Estradiol is a neuroprotective factor in the adult and aging brain: understanding of mechanisms derived from in vivo and in vitro studies Brain Res. Brain Res. Rev. 37 2001 313 319
49. D.W. Wright, A.L. Kellerman, V.S. Hertzberg, P.L. Clark, M. Frankel, F.C. Goldstein, J.P. Salomone, L.L. Dent, O.A. Harris, D.S. Ander, D.W. Lowery, M.M. Patel, D.D. Denson, A.B. Gordon, M.M. Wald, S. Gupta, S.W. Hoffman, and D.G. Stein ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury Ann. Emerg. Med. 49 2007 391 402
50. G. Xiao, J. Wei, W. Yan, and Z. Lu Improved outcomes from the administration of progesterone to patients with acute severe traumatic brain injury: a randomized controlled trial Crit. Care 12 2008 R61
51. T. Yahata, T. Kurabayashi, A. Honda, Y. Tojo, K. Tanaka, and T. Abo Physiological dose of estrogen regulated extrathymic T cells in female mice Cell. Immunol. 171 1996 269 276