Investigation of K14/K5 as a stem cell marker in the limbal region of the bovine cornea

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Chen, Bo ^a   Mi, Shengli ^a   Wright, Bernice ^a   Connon, Che John ^a  

^a UNIVERSITY OF READING   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 14; CYTOKERATIN 5; BIOLOGICAL MARKER;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORNEA EPITHELIUM; COW; EPITHELIUM CELL; HUMAN; HUMAN TISSUE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; ANIMAL; CATTLE; CORNEA LIMBUS; CYTOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; POLYMERASE CHAIN REACTION; STEM CELL; WESTERN BLOTTING;

BOVINAE; MAMMALIA;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CATTLE; IMMUNOHISTOCHEMISTRY; KERATIN-14; KERATIN-5; LIMBUS CORNEAE; POLYMERASE CHAIN REACTION; STEM CELLS;

EID: 78049262964     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013192     Document Type: Article

References (35)

1. Cotsarelis G, Cheng SZ, Dong G, Sun TT, Lavker RM (1989) Existence of slowcycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell 57: 201-209.
2. Lavker RM, Sun TT (2003) Epithelial stem cells: The eye provides a vision. Eye 17: 937-942.
3. Lehrer MS, Sun TT, Lavker RM (1998) Strategies of epithelial repair: modulation of stem cell and transit amplifying cell proliferation. J Cell Sci 111(Pt 19): 2867-2875.
4. Majo F, Rochat A, Nicolas M, Jaoude GA, Barrandon Y (2008) Oligopotent stem cells are distributed throughout the mammalian ocular surface. Nature 456: 250-254.
5. Mukhopadhyay M, Gorivodsky M, Shtrom S, Grinberg A, Niehrs C, et al. (2006) Dkk2 play an essential role in the corneal fate of the ocular surface epithelium. Development 133: 2149-2154.
6. Djalilian ARNA, Ito A, Balali S, Afshar A, Lavker RM, et al. (2008) Downregulation of Notch signaling during corneal epithelial proliferation Molecular Vision 14: 1041-1049.
7. Ma A, Zhao B, Connon CJ, Cai J, Albon J (2007) A role for Notch signaling in human corneal epithelial cell differentiation and proliferation Invest Ophthalmol Vis Sci 48: 3576-3585.
8. Pellegrini G, Dellambra E, Golisano O, Martinelli E, Fantozzi I, et al. (2001) p63 identifies keratinocyte stem cells. Proc Natl Acad Sci U S A 98: 3156-3161.
9. Watanabe K, Nishida K, Yamato M, Umemoto T, Sumide T, et al. (2004) Human limbal epithelium contains side population cells expressing the ATPbinding cassette transporter ABCG2. FEBS Lett 565: 6-10.
10. Zhao B, Allinson SL, Ma A, Bentley AJ, Martin FL, et al. (2008) Targeted cornea limbal stem/progenitor cell transfection in an organ culture model. Invest Ophthalmol Vis Sci 49: 3395-3401.
11. Schermer A, Galvin S, Sun TT (1986) Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol 103: 49-62.
12. Kurpakus MA, Stock EL, Jones JC (1990) Expression of the 55-kD/64-kD corneal keratins in ocular surface epithelium. Invest Ophthalmol Vis Sci 31: 448-456.
13. Chaloin-Dufau C, Sun TT, Dhoually D (1990) Appearance of Keratin pair K3/ K12 during embryonic and adult corneal epithelial differentiation in the chick and in the rabbit. Cell Differentiation and Development 32: 97-108.
14. Matic M, Petrov IN, Chen S, Wang C, Dimitrijevich SD, et al. (1997) Stem cells of the corneal epithelium lack connexins and metabolite transfer capacity. Differentiation 61: 251-260.
15. Kenyon KR, Tseng SC (1989) Limbal autograft transplantation for ocular surface disorders. Ophthalmology 96: 709-722; discussion 722-703.
16. Secker GA, Daniels JT (2008) Corneal epithelial stem cells: deficiency and regulation. Stem Cell Rev 4: 159-168.
17. Pellegrini G, Traverso CE, Franzi AT, Zingirian M, Cancedda R, et al. (1997) Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 349: 990-993.
18. Chen B, Mi S, Wright B, Connon CJ (2010) Differentiation status of limbal epithelial cells cultured on intact and denuded amniotic membrane before and after air-lifting. Tissue Eng Part A 16: 2721-2729.
19. Romano AC, Espana EM, Yoo SH, Budak MT, Wolosin JM, et al. (2003) Different cell sizes in human limbal and central corneal basal epithelia measured by confocal microscopy and flow cytometry. Invest Ophthalmol Vis Sci 44: 5125-5129.
20. Pellegrini G, Golisano O, Paterna P, Lambiase A, Bonini S, et al. (1999) Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface. J Cell Biol 145: 769-782.
21. Metallo CM, Ji L, de Pablo JJ, Palecek SP (2010) Directed differentiation of human embryonic stem cells to epidermal progenitors. Methods Mol Biol 585: 83-92.
22. Bickenbach JR (2005) Isolation, characterization, and culture of epithelial stem cells. Methods Mol Biol 289: 97-102.
23. Kurpakus MA, Maniaci MT, Esco M (1994) Expression of keratins K12, K4 and K14 during development of ocular surface epithelium. Curr Eye Res 13: 805-814.
24. Barnard Z, Apel AJ, Harkin DG (2001) Phenotypic analyses of limbal epithelial cell cultures derived from donor corneoscleral rims. Clin Experiment Ophthalmol 29: 138-142.
25. Hsueh YJ, Wang DY, Cheng CC, Chen JK (2004) Age-related expressions of p63 and other keratinocyte stem cell markers in rat cornea. J Biomed Sci 11: 641-651.
26. Wang DY, Hsueh YJ, Yang VC, Chen JK (2003) Propagation and phenotypic preservation of rabbit limbal epithelial cells on amniotic membrane. Invest Ophthalmol Vis Sci 44: 4698-4704.
27. Higa K, Shimmura S, Kato N, Kawakita T, Miyashita H, et al. (2007) Proliferation and differentiation of transplantable rabbit epithelial sheets engineered with or without an amniotic membrane carrier. Invest Ophthalmol Vis Sci 48: 597-604.
28. Prunieras M, Regnier M, Woodley D (1983) Methods for cultivation of keratinocytes with an air-liquid interface. J Invest Dermatol 81: 28s-33s.
29. Williams ML, Brown BE, Monger DJ, Grayson S, Elias PM (1988) Lipid content and metabolism of human keratinocyte cultures grown at the air-medium interface. J Cell Physiol 136: 103-110.
30. Mi S, Chen B, Wright B, Connon CJ (2010) Ex vivo construction of an artificial ocular surface by combination of corneal limbal epithelial cells and a compressed collagen scaffold containing keratocytes. Tissue Eng Part A 16: 2091-2100.
31. Mimura T, Amano S, Yokoo S, Uchida S, Yamagami S, et al. (2008) Tissue engineering of corneal stroma with rabbit fibroblast precursors and gelatin hydrogels. Mol Vis 14: 1819-1828.
32. Davanger M, Evensen A (1971) Role of the pericorneal papillary structure in renewal of corneal epithelium. Nature 229: 560-561.
33. Huang AJ, Tseng SC (1991) Corneal epithelial wound healing in the absence of limbal epithelium. Investigative Ophthalmology & Visual Science 32: 96-105.
34. Lavker RM, Dong G, Cheng SZ, Kudoh K, Cotsarelis G, et al. (1991) Relative proliferative rates of limbal and corneal epithelia. Implications of corneal epithelial migration, circadian rhythm, and suprabasally located DNAsynthesizing keratinocytes. Invest Ophthalmol Vis Sci 32: 1864-1875.
35. Yoshida S, Shimmura S, Kawakita T, Miyashita H, Den S, et al. (2006) Cytokeratin 15 can be used to identify the limbal phenotype in normal and diseased ocular surfaces. Invest Ophthalmol Vis Sci 47: 4780-4786.