E-cadherin and β-catenin expression in canine colorectal adenocarcinoma

Research in Veterinary Science

Volumn 89, Issue 3, 2010, Pages 409-414

  Aresu, L ^a   Pregel, P ^b   Zanetti, R ^a   Caliari, D ^a   Biolatti, B ^b   Castagnaro, M ^a  

^a Facoltà di Medicina Veterinaria   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Cadherins; Dog; Down regulation; Immunohistochemistry

Indexed keywords

BETA CATENIN; UVOMORULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER CLASSIFICATION; CANCER GRADING; CANCER INVASION; CANCER SIZE; CELL JUNCTION; CELLULAR DISTRIBUTION; CLINICAL EVALUATION; COLON CARCINOGENESIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; DISEASE ASSOCIATION; DOG; DOWN REGULATION; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE MUCOSA; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ADENOCARCINOMA; ADENOCARCINOMA, MUCINOUS; ADENOCARCINOMA, PAPILLARY; ANIMALS; BETA CATENIN; CADHERINS; CARCINOMA, ACINAR CELL; CARCINOMA, ADENOSQUAMOUS; COLORECTAL NEOPLASMS; DOG DISEASES; DOGS; DOWN-REGULATION; FEMALE; INTESTINAL MUCOSA; MALE;

CANIS FAMILIARIS;

EID: 78049244868     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2010.04.008     Document Type: Article

References (25)

1. Alattia J.R., Kurokawa H., Ikura M. Structural view of cadherin-mediated cell-cell adhesion. Cell Mol. Life Sci. 1999, 55:359-367.
2. Aust D.E., Terdiman J.P., Willenbucher R.F., Chew K., Ferrell L., Florendo C., Molinaro-Clark A., Baretton G.B., Löhrs U., Waldman F.M. Altered distribution of beta-catenin, and its binding proteins E-cadherin and APC, in ulcerative colitis-related colorectal cancers. Mod. Pathol. 2001, 14:29-39.
3. Bondi J., Bukholm G., Nesland J.M., Bakka A., Bukholm I.R. An increase in the number of adhesion proteins with altered expression is associated with an increased risk of cancer death for colon carcinoma patients. Int. J. Colorectal Dis. 2006, 21:231-237.
4. Conacci-Sorrell M., Simcha I., Ben-Yedidia T., Blechman J., Savagner P., Ben-Ze'ev A. Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, slug, and MAPK. J. Cell Biol. 2003, 163:847-857.
5. Elangbam C.S., Qualls C.W., Dahlgren R.R. Cell adhesion molecules-update. Vet. Pathol. 1997, 34:61-73.
6. El-Bahrawy M.A., Poulsom R., Jeffery R., Talbot I., Alison M.R. The expression of E-cadherin and catenins in sporadic colorectal carcinoma. Hum. Pathol. 2001, 32:1216-1224.
7. Hao X., Tomlinson I., Ilyas M., Palazzo J.P., Talbot I.C. Reciprocity between membranous and nuclear expression of beta-catenin in colorectal tumours. Virchows Arch. 1997, 431:167-172.
8. Harrington K.J., Syrigos K.N. The role of E-cadherin-catenin complex: more than an intercellular glue?. Ann. Surg. Oncol. 2000, 7:783-788.
9. Joo Y.E., Rew J.S., Choi S.K., Bom H.S., Park C.S., Kim S.J. Expression of e-cadherin and catenins in early gastric cancer. J. Clin. Gastroenterol. 2002, 35:35-42.
10. Jungck M., Grünhage F., Spengler U., Dernac A., Mathiak M., Caspari R., Friedl W., Sauerbruch T. E-cadherin expression is homogeneously reduced in adenoma from patients with familial adenomatous polyposis: an immunohistochemical study of E-cadherin, beta-catenin and cyclooxygenase-2 expression. Int. J. Colorectal Dis. 2004, 19:438-445.
11. Kitagawa T., Matsumoto K., Nagafuchi A., Tsukita S., Suzuki H. Co-expression of E-cadherin and alpha-catenin molecules in colorectal cancer. Surg. Today 1999, 29:511-518.
12. Kwak J.M., Min B.W., Lee J.H., Choi J.S., Lee S.I., Park S.S., Kim J., Um J.W., Kim S.H., Moon H.Y. The prognostic significance of E-cadherin and liver intestine-cadherin expression in colorectal cancer. Dis. Colon Rectum 2007, 50:1873-1880.
13. Masszi A., Fan L., Rosivall L., McCulloch C.A., Rotstein O.D., Mucsi I., Kapus A. Integrity of cell-cell contacts is a critical regulator of TGF-beta 1-induced epithelial-to-myofibroblast transition: role for beta-catenin. Am. J. Pathol. 2004, 165:1955-1967.
14. McEntee M.F., Brenneman K.A. Dysregulation of beta-catenin is common in canine sporadic colorectal tumors. Vet. Pathol. 1999, 36:228-236.
15. Morin P.J. Beta-catenin signaling and cancer. Bioessays 1999, 21:1021-1030.
16. Morton R.A., Ewing C.M., Nagafuchi A., Tsukita S., Isaacs W.B. Reduction of E-cadherin levels and deletion of the alpha-catenin gene in human prostate cancer cells. Cancer Res. 1993, 53:3585-3590.
17. Oyama T., Kanai Y., Ochiai A., Akimoto S., Oda T., Yanagihara K., Nagafuchi A., Tsukita S., Shibamoto S., Ito F. A truncated beta-catenin disrupts the interaction between E-cadherin and alpha-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines. Cancer Res. 1994, 54:6282-6287.
18. Park S.S., Kang S.H., Park J.M., Kim J.H., Oh S.C., Lee J.H., Chae Y.S., Kim S.J., Kim C.S., Mok Y.J. Expression of liver-intestine cadherin and its correlation with lymph node metastasis in gastric cancer: can it predict N stage preoperatively?. Ann. Surg. Oncol. 2007, 14:94-99.
19. Richmond P.J., Karayiannakis A.J., Nagafuchi A., Kaisary A.V., Pignatelli M. Aberrant E-cadherin and alpha-catenin expression in prostate cancer: correlation with patient survival. Cancer Res. 1997, 57:3189-3193.
20. Salon C., Moro D., Lantuejoul S., Brichon Py.P., Drabkin H., Brambilla C., Brambilla E. E-cadherin-beta-catenin adhesion complex in neuroendocrine tumors of the lung: a suggested role upon local invasion and metastasis. Hum. Pathol. 2004, 35:1148-1155.
21. Schandl L., Ebert M.P., Malfertheiner P. Cadherins and catenins in inflammation and oncogenesis. Dig. Liver Dis. 2000, 32(Suppl. 3):S184-S187.
22. Takayama T., Shiozaki H., Shibamoto S. Beta-catenin expression in human cancers. Am. J. Pathol. 1996, 148:39-46.
23. Tetsu O., McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999, 398:422-426.
24. Wong S.C., Lo E.S., Chan A.K., Lee K.C., Lee K.C., Hsiao W.L. Nuclear beta catenin as a potential prognostic and diagnostic marker in patients with colorectal cancer from Hong Kong. Mol. Pathol. 2003, 56:347-352.
25. Wong S.C., Lo E.S., Lee K.C., Chan J.K., Hsiao W.L. Prognostic and diagnostic significance of beta-catenin nuclear immunostaining in colorectal cancer. Clin. Cancer Res. 2004, 10:1401-1408.