Differential regulation of chemokine expression by estrogen in human periodontal ligament cells

Journal of Periodontal Research

Volumn 45, Issue 6, 2010, Pages 796-802

  Nebel, D ^a,b   Jonsson D ^a,b   Norderyd, O ^b   Bratthall, G ^b   Nilsson, B O ^a  

^a LUND UNIVERSITY   (Sweden)

^b MALMÖ UNIVERSITY   (Sweden)

Author keywords

Chemokines; Estrogen; Inflammation; Periodontal ligament cells

Indexed keywords

CCL2 PROTEIN, HUMAN; CCL3 PROTEIN, HUMAN; CCL5 PROTEIN, HUMAN; ESTRADIOL; ESTROGEN; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES;

ADOLESCENT; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DRUG EFFECT; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; PERIODONTAL LIGAMENT; PHYSIOLOGY;

ADOLESCENT; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOKINE CCL3; CHEMOKINE CCL5; ESTRADIOL; ESTROGENS; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; LIPOPOLYSACCHARIDES; MALE; PERIODONTAL LIGAMENT;

EID: 77958577690     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2010.01308.x     Document Type: Article

References (34)

1. Nilsson S, Mäkelä S, Treuter E et al. Mechanisms of estrogen action. Physiol Rev 2001;81:1535-1565.
2. Muramatsu M, Inoue S. Estrogen receptors: how do they control reproductive and nonreproductive functions? Biochem Biophys Res Commun 2000;270:1-10.
3. Lewko WM, Anderson A. Estrogen receptors and growth response in cultured human periodontal ligament cells. Life Sci 1986;39:1201-1206.
4. Morishita M, Shimazu A, Iwamoto Y. Analysis of oestrogen receptor mRNA by reverse transcriptase-polymerase chain reaction in human periodontal ligament cells. Arch Oral Biol 1999;44:781-783.
5. Jönsson D, Andersson G, Ekblad E, Liang M, Bratthall G, Nilsson BO. Immunocytochemical demonstration of estrogen receptor β in human periodontal ligament cells. Arch Oral Biol 2004;49:85-88.
6. Jönsson D, Nilsson J, Odenlund M et al. Demonstration of mitochondrial oestrogen receptor β and oestrogen-induced attenuation of cytochrome c oxidase subunit I expression in human periodontal ligament cells. Arch Oral Biol 2007;52:669-676.
7. Jönsson D, Wahlin Å, Idvall I, Johnsson I, Bratthall G, Nilsson BO. Differential effects of estrogen on DNA synthesis in human periodontal ligament and breast cancer cells. J Periodontal Res 2005;40:401-406.
8. Somerman MJ, Young MF, Foster RA, Moehring M, Imm GR, Sauk JJ. Characteristics of human periodontal ligament cells in vitro. Arch Oral Biol 1990;35:241-247.
9. Yamaji Y, Kubota T, Sasaguri K et al. Inflammatory cytokine gene expression in human periodontal ligament fibroblasts stimulated with bacterial lipopolysaccharides. Infect Immun 1995;63:3576-3581.
10. Yamamoto T, Kita M, Oseko F, Nakamura T, Imanishi J, Kanamura N. Cytokine production in human periodontal ligament cells stimulated with Porphyromonas gingivalis. J Periodontal Res 2006;41:554-559.
11. Jönsson D, Nebel D, Bratthall G, Nilsson BO. LPS-induced MCP-1 and IL-6 production is not reversed by oestrogen in human periodontal ligament cells. Arch Oral Biol 2008;53:896-902.
12. Carlsten H. Immune responses and bone loss: the estrogen connection. Immunol Rev 2005;208:194-206.
13. Obendorf M, Patchev VK. Interactions of sex steroids with mechanisms of inflammation. Curr Drug Targets Inflamm Allergy 2004;3:425-433.
14. Nilsson BO. Modulation of the inflammatory response by estrogens with focus on the endothelium and its interactions with leukocytes. Inflamm Res 2007;56:269-273.
15. Mikkola TS, St Clair RW. Estradiol reduces basal and cytokine induced monocyte adhesion to endothelial cells. Maturitas 2002;41:313-319.
16. Mori M, Tsukahara F, Yoshioka T, Irie K, Ohta H. Suppression by 17beta-estradiol of monocyte adhesion to vascular endothelial cells is mediated by estrogen receptors. Life Sci 2004;75:599-609.
17. Gao H, Liang M, Bergdahl A et al. Estrogen attenuates vascular expression of inflammation associated genes and adhesion of monocytes to endothelial cells. Inflamm Res 2006;55:349-353.
18. Caulin-Glaser T, Watson CA, Pardi R, Bender JR. Effects of 17β-estradiol on cytokine-induced endothelial cell adhesion molecule expression. J Clin Invest 1996;98:36-42.
19. Simoncini T, Maffei S, Basta G et al. Estrogens and glucocorticoids inhibit endothelial vascular cell adhesion molecule-1 expression by different transcriptional mechanisms. Circ Res 2000;87:19-25.
20. Mukherjee TK, Nathan L, Dinh H, Reddy ST, Chaudhuri G. 17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. J Biol Chem 2003;278:11746-11752.
21. Frazier-Jessen MR, Kovacs EJ. Estrogen modulation of JE/monocyte chemoattractant protein-1 mRNA expression in murine macrophages. J Immunol 1995;154:1838-1845.
22. Inadera H, Sekiya T, Yoshimura T, Matsushima K. Molecular analysis of the inhibition of monocyte chemoattractant protein-1 gene expression by estrogens and xenoestrogens in MCF-7 cells. Endocrinology 2000;141:50-59.
23. Kelner GS, Zlotnik A. Cytokine production profile on early thymocytes and the characterization of a new class of chemokine. J Leukoc Biol 1995;57:778-781.
24. Maurer M, Von Stebut E. Macrophage inflammatory protein-1. Int J Biochem Cell Biol 2004;36:1882-1886.
25. Deshmane SL, Kremlev S, Amini S, Sawaya BE. Monocyte chemoattractant protein-1 (MCP-1): an overview. J Interferon Cytokine Res 2009;29:313-326.
26. Pradeep AR, Daisy H, Hadge P et al. Correlation of gingival crevicular fluid interleukin-18 and monocyte chemoattractant protein-1 levels in periodontal health and disease. J Periodontol 2009;80:1454-1461.
27. Pradeep AR, Daisya H, Hadge P. Gingival crevicular fluid levels of monocyte chemoattractant protein-1 in periodontal health and disease. Arch Oral Biol 2009;54:503-509.
28. Garlet GP, Martins W Jr, Ferreira BR et al. Patterns of chemokines and chemokine receptors expression in different forms of human periodontal disease. J Periodontal Res 2003;38:210-217.
29. Scheres N, Laine ML, De Vries TJ, Everts V, Van Winkelhoff AJ. Gingival and periodontal ligament fibroblasts differ in their inflammatory response to viable Porphyromonas gingivalis. J Periodontal Res 2010;45:262-270.
30. Pfaffl MW. A new mathematical model for realtive quantification in real-time RT-PCR. Nucleic Acids Res 2001;29:e:45.
31. Cornil CA, Ball GF, Balthazart J. Functional significance of the rapid regulation of brain estrogen action: where do the estrogens come from? Brain Res 2006;1126:2-26.
32. Patil C, Rossa C Jr, Kirkwood KL. Actinobacillus actinomycetemcomitans lipopolysaccharide induces interleukin-6 expression through multiple mitogen-activated protein kinase pathways in periodontal ligament fibroblasts. Oral Microbiol Immunol 2006;21:392-398.
33. Ryu OH, Choi SJ, Linares AMG et al. Gingival epithelial cell expression of macrophage inflammatory protein-1α induced by interleukin-1β and lipopolysaccharide. J Periodontol 2007;78:1627-1634.
34. Jönsson D, Amisten S, Bratthall G, Holm A, Nilsson BO. LPS induces GROα chemokine production via NF-κB in oral fibroblasts. Inflamm Res 2009;58:791-796.