C331A mutant of neuronal nitric-oxide synthase is labilized for Hsp70/CHIP (C terminus of HSC70-interacting protein)-dependent ubiquitination

Journal of Biological Chemistry

Volumn 285, Issue 44, 2010, Pages 33642-33651

  Clapp, Kelly M ^a   Peng, Hwei Ming ^a   Morishima, Yoshihiro ^a   Lau, Miranda ^a   Walker, Vyvyca J ^a   Pratt, William B ^a   Osawa, Yoichi ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; C TERMINUS; D-ISOMERS; EXPERIMENTAL SYSTEM; GENERAL MODEL; HEK293 CELLS; L-ARGININE; NEURONAL NITRIC-OXIDE SYNTHASE (NNOS); NITRIC-OXIDE SYNTHASE; PROTEASOMAL DEGRADATION; PROTEIN QUALITY CONTROL; SUBSTRATE-BINDING; SUICIDE INACTIVATION; TETRAHYDROBIOPTERIN; UBIQUITIN LIGASES; UBIQUITINATION;

BIOCHEMISTRY; DEGRADATION; ENZYMES; MACHINERY; PORPHYRINS; POSITIVE IONS;

AMINO ACIDS;

ARGININE; CARBOXY TERMINAL OF HSC70 INTERACTING PROTEIN; CHAPERONE; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; N(G) NITROARGININE; NEURONAL NITRIC OXIDE SYNTHASE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; QUALITY CONTROL; RAT; RETICULOCYTE; UBIQUITINATION; WESTERN BLOTTING;

CATALYTIC DOMAIN; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CYTOCHROME P-450 ENZYME SYSTEM; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LIGANDS; MOLECULAR CHAPERONES; MUTATION; NITRIC OXIDE SYNTHASE TYPE I; PROTEIN STRUCTURE, TERTIARY; SUBCELLULAR FRACTIONS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; XENOBIOTICS;

EID: 77958565865     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.159178     Document Type: Article

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