-
1
-
-
33845444046
-
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
-
Druker BJ, Guilhot F, O'Brien SG, et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 2006;355:2408-17.
-
(2006)
N Engl J Med
, vol.355
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
-
2
-
-
36348968931
-
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance
-
Kantarjian HM, Giles F, Gattermann N, et al. Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance. Blood 2007;110:3540-6.
-
(2007)
Blood
, vol.110
, pp. 3540-3546
-
-
Kantarjian, H.M.1
Giles, F.2
Gattermann, N.3
-
3
-
-
45149087139
-
Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib
-
Hochhaus A, Baccarani M, Deininger M, et al. Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib. Leukemia 2008;22:1200-6.
-
(2008)
Leukemia
, vol.22
, pp. 1200-1206
-
-
Hochhaus, A.1
Baccarani, M.2
Deininger, M.3
-
4
-
-
37049014938
-
Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets
-
Rix U, Hantschel O, Durnberger G, et al. Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets. Blood 2007;110:4055-63.
-
(2007)
Blood
, vol.110
, pp. 4055-4063
-
-
Rix, U.1
Hantschel, O.2
Durnberger, G.3
-
5
-
-
33846023983
-
Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years
-
Rousselot P, Huguet F, Rea D, et al. Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years. Blood 2007;109:58-60.
-
(2007)
Blood
, vol.109
, pp. 58-60
-
-
Rousselot, P.1
Huguet, F.2
Rea, D.3
-
6
-
-
72149110499
-
Is It Possible to Stop Imatinib in Patients with Chronic Myeloid Leukemia? An Update from a French Pilot Study and First Results from the Multicentre « Stop Imatinib » (STIM) Study
-
Abstract 187, 2008.
-
Mahon FX, Huguet F, Guilhot F, et al. Is It Possible to Stop Imatinib in Patients with Chronic Myeloid Leukemia? An Update from a French Pilot Study and First Results from the Multicentre « Stop Imatinib » (STIM) Study. Blood 2008;112. Abstract 187, 2008.
-
(2008)
Blood
, vol.112
-
-
Mahon, F.X.1
Huguet, F.2
Guilhot, F.3
-
7
-
-
35548978472
-
Appearance of bone marrow lymphocytosis predicts an optimal response to imatinib therapy in patients with chronic myeloid leukemia
-
Mustjoki S, Lundan T, Knuutila S, Porkka K. Appearance of bone marrow lymphocytosis predicts an optimal response to imatinib therapy in patients with chronic myeloid leukemia. Leukemia 2007;21:2363-8.
-
(2007)
Leukemia
, vol.21
, pp. 2363-2368
-
-
Mustjoki, S.1
Lundan, T.2
Knuutila, S.3
Porkka, K.4
-
8
-
-
65949085379
-
Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients
-
Menard C, Blay JY, Borg C, et al. Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients. Cancer Res 2009;69:3563-9.
-
(2009)
Cancer Res
, vol.69
, pp. 3563-3569
-
-
Menard, C.1
Blay, J.Y.2
Borg, C.3
-
9
-
-
42249088418
-
Profound inhibition of antigen-specific T-cell effector functions by dasatinib
-
Weichsel R, Dix C, Wooldridge L, et al. Profound inhibition of antigen-specific T-cell effector functions by dasatinib. Clin Cancer Res 2008;14:2484-91.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2484-2491
-
-
Weichsel, R.1
Dix, C.2
Wooldridge, L.3
-
10
-
-
45449102076
-
The Src/ABL kinase inhibitor dasatinib (BMS-354825) inhibits function of normal human T-lymphocytes in vitro
-
Blake S, Hughes TP, Mayrhofer G, Lyons AB. The Src/ABL kinase inhibitor dasatinib (BMS-354825) inhibits function of normal human T-lymphocytes in vitro. Clin Immunol 2008;127:330-9.
-
(2008)
Clin Immunol
, vol.127
, pp. 330-339
-
-
Blake, S.1
Hughes, T.P.2
Mayrhofer, G.3
Lyons, A.B.4
-
11
-
-
38949210227
-
Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation
-
Schade AE, Schieven GL, Townsend R, Jankowska AM, Susulic V, Zhang R, Szpurka H, Maciejewski JP. Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation. Blood 2008;111:1366-77.
-
(2008)
Blood
, vol.111
, pp. 1366-1377
-
-
Schade, A.E.1
Schieven, G.L.2
Townsend, R.3
Jankowska, A.M.4
Susulic, V.5
Zhang, R.6
Szpurka, H.7
Maciejewski, J.P.8
-
12
-
-
53749086585
-
Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signalling
-
Chen J, Schmitt A, Chen B, et al. Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signalling. J Cell Mol Med 2008;12:2107-18.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 2107-2118
-
-
Chen, J.1
Schmitt, A.2
Chen, B.3
-
13
-
-
0028243540
-
Role of tyrosine kinases in lymphocyte activation
-
Sefton BM, Taddie JA. Role of tyrosine kinases in lymphocyte activation. Curr Opin Immunol 1994;6:372-9.
-
(1994)
Curr Opin Immunol
, vol.6
, pp. 372-379
-
-
Sefton, B.M.1
Taddie, J.A.2
-
14
-
-
43249096013
-
Dasatinib suppresses in vitro natural killer cell cytotoxicity
-
Blake SJ, Bruce Lyons A, Fraser CK, Hayball JD, Hughes TP. Dasatinib suppresses in vitro natural killer cell cytotoxicity. Blood 2008;111:4415-6.
-
(2008)
Blood
, vol.111
, pp. 4415-4416
-
-
Blake, S.J.1
Bruce Lyons, A.2
Fraser, C.K.3
Hayball, J.D.4
Hughes, T.P.5
-
15
-
-
58149267985
-
Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia
-
Kim DH, Kamel-Reid S, Chang H, Sutherland R, Jung CW, Kim HJ, Lee JJ, Lipton JH. Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia. Haematologica 2009;94:135-9.
-
(2009)
Haematologica
, vol.94
, pp. 135-139
-
-
Kim, D.H.1
Kamel-Reid, S.2
Chang, H.3
Sutherland, R.4
Jung, C.W.5
Kim, H.J.6
Lee, J.J.7
Lipton, J.H.8
-
16
-
-
68749108104
-
Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
-
Mustjoki S, Ekblom M, Arstila TP, et al. Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. Leukemia 2009;23:1398-405.
-
(2009)
Leukemia
, vol.23
, pp. 1398-1405
-
-
Mustjoki, S.1
Ekblom, M.2
Arstila, T.P.3
-
17
-
-
70449467570
-
Immunosuppression and atypical infections in CML patients treated with dasatinib at 140 mg daily
-
Sillaber C, Herrmann H, Bennett K, et al. Immunosuppression and atypical infections in CML patients treated with dasatinib at 140 mg daily. Eur J Clin Invest 2009;39:1098-109.
-
(2009)
Eur J Clin Invest
, vol.39
, pp. 1098-1109
-
-
Sillaber, C.1
Herrmann, H.2
Bennett, K.3
-
18
-
-
58249105216
-
Does chemotherapy modify the immune surveillance of hematological malignancies?
-
Barrett AJ, Savani BN. Does chemotherapy modify the immune surveillance of hematological malignancies? Leukemia 2009;23:53-8.
-
(2009)
Leukemia
, vol.23
, pp. 53-58
-
-
Barrett, A.J.1
Savani, B.N.2
-
19
-
-
13844312036
-
Effect of a p210 multipeptide vaccine associated with imatinib or interferon in patients with chronic myeloid leukaemia and persistent residual disease: a multicentre observational trial
-
Bocchia M, Gentili S, Abruzzese E, et al. Effect of a p210 multipeptide vaccine associated with imatinib or interferon in patients with chronic myeloid leukaemia and persistent residual disease: a multicentre observational trial. Lancet 2005;365:657-62.
-
(2005)
Lancet
, vol.365
, pp. 657-662
-
-
Bocchia, M.1
Gentili, S.2
Abruzzese, E.3
-
20
-
-
35449008469
-
Clinical evaluation of BCR-ABL peptide immunisation in chronic myeloid leukaemia: results of the EPIC study
-
Rojas JM, Knight K, Wang L, Clark RE. Clinical evaluation of BCR-ABL peptide immunisation in chronic myeloid leukaemia: results of the EPIC study. Leukemia 2007;21:2287-95.
-
(2007)
Leukemia
, vol.21
, pp. 2287-2295
-
-
Rojas, J.M.1
Knight, K.2
Wang, L.3
Clark, R.E.4
-
21
-
-
56849090964
-
The role of NKT cells in tumor immunity
-
Terabe M, Berzofsky JA. The role of NKT cells in tumor immunity. Adv Cancer Res 2008;101:277-348.
-
(2008)
Adv Cancer Res
, vol.101
, pp. 277-348
-
-
Terabe, M.1
Berzofsky, J.A.2
-
22
-
-
0031660446
-
CD57+/CD28- T cells in untreated hemato-oncological patients are expanded and display a Th1-type cytokine secretion profile, ex vivo cytolytic activity and enhanced tendency to apoptosis
-
Van den Hove LE, Van Gool SW, Vandenberghe P, Boogaerts MA, Ceuppens JL. CD57+/CD28- T cells in untreated hemato-oncological patients are expanded and display a Th1-type cytokine secretion profile, ex vivo cytolytic activity and enhanced tendency to apoptosis. Leukemia 1998;12:1573-82.
-
(1998)
Leukemia
, vol.12
, pp. 1573-1582
-
-
Van den Hove, L.E.1
Van Gool, S.W.2
Vandenberghe, P.3
Boogaerts, M.A.4
Ceuppens, J.L.5
-
23
-
-
0032006459
-
Peripheral blood lymphocyte subset shifts in patients with untreated hematological tumors: evidence for systemic activation of the T cell compartment
-
Van den Hove LE, Vandenberghe P, Van Gool SW, Ceuppens JL, Demuynck H, Verhoef GE, Boogaerts MA. Peripheral blood lymphocyte subset shifts in patients with untreated hematological tumors: evidence for systemic activation of the T cell compartment. Leuk Res 1998;22:175-84.
-
(1998)
Leuk Res
, vol.22
, pp. 175-184
-
-
Van den Hove, L.E.1
Vandenberghe, P.2
Van Gool, S.W.3
Ceuppens, J.L.4
Demuynck, H.5
Verhoef, G.E.6
Boogaerts, M.A.7
-
24
-
-
0141889279
-
Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation
-
Rezvani K, Grube M, Brenchley JM, et al. Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation. Blood 2003;102:2892-900.
-
(2003)
Blood
, vol.102
, pp. 2892-2900
-
-
Rezvani, K.1
Grube, M.2
Brenchley, J.M.3
-
25
-
-
77956280601
-
Mono/oligoclonal T- and NK-cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy
-
April 22 (Epub ahead of print).
-
Kreutzman A, Juvonen V, Kairisto V, Ekblom M, Stenke L, Seggewiss R, Porkka K, Mustjoki S. Mono/oligoclonal T- and NK-cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy. Blood. 2010 April 22 (Epub ahead of print).
-
(2010)
Blood
-
-
Kreutzman, A.1
Juvonen, V.2
Kairisto, V.3
Ekblom, M.4
Stenke, L.5
Seggewiss, R.6
Porkka, K.7
Mustjoki, S.8
-
26
-
-
42649131674
-
Roles of CD4+CD25(high) FOXP3+ Tregs in lymphomas and tumors are complex
-
Ke X, Wang J, Li L, Chen IH, Wang H, Yang XF. Roles of CD4+CD25(high) FOXP3+ Tregs in lymphomas and tumors are complex. Front Biosci 2008;13:3986-4001.
-
(2008)
Front Biosci
, vol.13
, pp. 3986-4001
-
-
Ke, X.1
Wang, J.2
Li, L.3
Chen, I.H.4
Wang, H.5
Yang, X.F.6
-
27
-
-
63849289233
-
High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow
-
Melenhorst JJ, Scheinberg P, Chattopadhyay PK, Gostick E, Ladell K, Roederer M, Hensel NF, Douek DC, Barrett AJ, Price DA. High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow. Blood 2009;113:2238-44.
-
(2009)
Blood
, vol.113
, pp. 2238-2244
-
-
Melenhorst, J.J.1
Scheinberg, P.2
Chattopadhyay, P.K.3
Gostick, E.4
Ladell, K.5
Roederer, M.6
Hensel, N.F.7
Douek, D.C.8
Barrett, A.J.9
Price, D.A.10
-
28
-
-
68149148869
-
Biomarkers of human immunosenescence: impact of Cytomegalovirus infection
-
Derhovanessian E, Larbi A, Pawelec G. Biomarkers of human immunosenescence: impact of Cytomegalovirus infection. Curr Opin Immunol 2009;21:440-5.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 440-445
-
-
Derhovanessian, E.1
Larbi, A.2
Pawelec, G.3
|