Frequency and role of HPV in the progression of epithelial dysplasia to oral cancer

Anticancer Research

Volumn 30, Issue 9, 2010, Pages 3435-3440

  Angiero, Francesca ^a   Gatta, Luisa Benerini ^b   Seramondi, Rossella ^c   Berenzi, Angiola ^b   Benetti, Anna ^b   Magistro, Sarah ^c   Ordesi, Paolo ^c   Grigolato, Piergiovanni ^b   Dessy, Enrico ^b  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

HPV; Oral carcinoma; Oral dysplasia; P16; P53

Indexed keywords

PROTEIN P16; PROTEIN P53; CYCLIN DEPENDENT KINASE INHIBITOR 2A; VIRUS DNA;

ADULT; AGED; ARTICLE; CANCER INVASION; COLORIMETRY; DYSPLASIA; EPITHELIUM HYPERPLASIA; FEMALE; GENE OVEREXPRESSION; GENOTYPE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MAJOR CLINICAL STUDY; MALE; MOUTH CANCER; ORAL BIOPSY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; WART VIRUS; ADOLESCENT; BIOSYNTHESIS; CELL TRANSFORMATION; CHILD; COMPLICATION; DISEASE COURSE; ISOLATION AND PURIFICATION; MIDDLE AGED; MOUTH TUMOR; PAPILLOMA VIRUS; PAPILLOMAVIRUS INFECTIONS; PATHOLOGY; PRECANCER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VERY ELDERLY; VIROLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION, NEOPLASTIC; CHILD; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DISEASE PROGRESSION; DNA, VIRAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; MOUTH NEOPLASMS; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; PRECANCEROUS CONDITIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53; YOUNG ADULT;

EID: 77958551283     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Ragin CC and Taioli E: Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: review and meta-analysis - review. Int J Cancer 121(8): 1813-1820, 2007.
2. Ragin CC, Modugno F and Gollin SM: The epidemiology and risk factors of head and neck cancer: a focus on human papillomavirus - review. J Dent Res 86(2): 104-114, 2007.
3. Curado MP and Hashibe M: Recent changes in the epidemiology of head and neck cancer. Curr Opin Oncol 21(5): 194-200, 2009.
4. Adelstein DJ, Ridge JA, Gillison ML, Chaturvedi AK, D'Souza G and Gravitt PE et al: Head and neck squamous cell cancer and the human papillomavirus: summary of a National Cancer Institute State of the Science Meeting, November 9-10, 2008, Washington, D.C. Head Neck 31(11): 1393-1422, 2009.
5. Ritchie JM, Smith EM, Summersgill KF, Hoffman HT, Wang D and Klussmann JP et al: Human papillomavirus infection as a prognostic factor in carcinomas of the oral cavity and oropharynx. Int J Cancer 104(3): 336-344, 2003.
6. Gillison ML, D'Souza G, Westra W, Sugar E, Xiao W, Begum S and Viscidi R: Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst 100(6): 407-420, 2008.
7. Letian T and Tianyu Z: Cellular receptor binding and entry of human papillomavirus. Virol J 7(1): 2, 2010.
8. Feller L, Khammissa RA, Wood NH and Lemmer J: Epithelial maturation and molecular biology of oral HPV. Infect Agent Cancer 25: 4-16, 2009.
9. Monk BJ and Wiley DJ: Will widespread human papillomavirus prophylactic vaccination change sexual practices of adolescent and young adult women in America? Obstet Gynecol 108(2): 420-424, 2006.
10. Nielsen H, Norrild B, Vedtofte P, Praetorius F, Reibel J and Holmstrup P: Human papillomavirus in oral premalignant lesions. Eur J Cancer B Oral Oncol 32B(4): 264-270, 1996. (Pubitemid 26246312)
11. Reichart PA and Philipsen HP: Oral erythroplakia - a review. Oral Oncol 41(6): 551-561, 2005.
12. Hennessey PT, Westra WH and Califano JA: Human papillomavirus and head and neck squamous cell carcinoma: recent evidence and clinical implications. J Dent Res 88(4): 300-306, 2009.
13. Ha PK and Califano JA: The role of human papillomavirus in oral carcinogenesis. Crit Rev Oral Biol Med 15(4): 188-196, 2004.
14. Mork J, Lie AK, Glattre E, Hallmans G, Jellum E and Koskela P et al: Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck. N Engl J Med 344(15): 1125-1131, 2001. (Pubitemid 32285233)
15. Ghittoni R, Accardi R, Hasan U, Gheit T, Sylla B and Tommasino M: The biological properties of E6 and E7 oncoproteins from human papillomaviruses. Virus Genes 40(1): 1-13, 2010.
16. Huh WK: Human papillomavirus infection: a concise review of natural history. Obstet Gynecol 114(1): 139-143, 2009.
17. Nemes JA, Deli L, Nemes Z and Márton IJ: Expression of p16(INK4A), p53, and Rb proteins are independent from the presence of human papillomavirus genes in oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102(3): 344-352, 2006.
18. Gale N, Pilch BZ and Sidramsky D (eds.): Epithelial precursor lesions. In: World Health Organization Classification of Tumours. Pathology and Genetics of Head and Neck Tumours. Lyon: IARC Press pp. 177-179, 2005.
19. Cruz IB, Snijders PJ, Meijer CJ, Braakhuis BJ, Snow GB and Walboomers JM et al: p53 expression above the basal cell layer in oral mucosa is an early event of malignant trasformation and has predictive value for developing oral squamous cell carcinoma. J Pathol 184: 360-368, 1998.
20. Pirog EC, Baergen RN, Soslow RA, Tam D, DeMattia AE and Chen YT: Diagnostic accuracy of cervical low-grade squamous intraepithelial lesions is improved with MIB-1 immunostaining. Am J Surg Pathol 26: 70-75, 2002.
21. Tanaka R, Wang D, Morishita Y, Inadome Y, Minami Y and Iijima T: Loss of function of p16 gene and prognosis of pulmonary adenocarcinoma. Cancer 103: 608-615, 2005.
22. Strome SE, Savva A, Brisett AE, Gostout BS, Lewis J and Clayton AC et al: Squamous cell carcinoma of the tonsils: a molecular analysis of HPV associations. Clin Cancer Res 8: 1093-1100, 2002.
23. D'souza G, Kreimer AR, Viscidi R, Pawlita M, Fakhry C and Koch WM et al: Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 356: 1944-1956, 2007.
24. Strati K, Pitot HC and Lambert PF: Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model. Proc Natl Acad Sci USA 103(38): 14152-14157, 2006.
25. Yamakawa-Kakuta Y, Kawamata H, Doi Y, Fujimori T and Imai Y: Does the expression of HPV16/18 E6/E7 in head and neck squamous cell carcinomas relate to their clinicopathological characteristics? Int J Oncol 35(5): 983-988, 2009.
26. Pande P, Mathur M, Shukla NK and Ralhan R: pRb and p16 protein alterations in human oral tumorigenesis. Oral Oncol 34: 396-403, 1998. (Pubitemid 28440304)
27. Buajeeb W, Poomsawat S, Punyasingh J and Sanguansin S: Expression of p16 in oral cancer and premalignant lesions. J Oral Pathol Med 38(1): 104-108, 2009.
28. INK4A, a new marker that correlates with dysplasia in oral squamoproliferative lesions. Am J Surg Pathol 29: 792-796, 2005.
29. INK4a and FHIT expression in carcinogenesis and progression of human oral cancer. Int J Oncol 24: 249-255, 2004.
30. Pai RK, Erickson J, Pourmand N and Kong CS: p16 (INK4A) immunohistochemical staining may be helpful in distinguishing branchial cleft cysts from cystic squamous cell carcinomas originating in the oropharynx. Cancer Cytopathol 117(2): 108-119, 2009.
31. Ralhan R, Chakravarti N, Kaur J, Sharma C, Kumar A, Mathur M et al: Clinical significance of altered expression of retinoid receptors in oral precancerous and cancerous lesions: relationship with cell cycle regulators. Int J Cancer 118: 1077-1089, 2006.
32. Anderson KM, Stoner GD, Fields HW, Chacon GE, Dohar AL, Gregg BR et al: Immunohistochemical assessment of Viadent-associated leukoplakia. Oral Oncol 41: 200-207, 2005.
33. INK4a in dysplastic lesions of the oral cavity. Mod Pathol 19: 1310-1316, 2006.
34. Queiroz C, Silva TC, Alves VA, Villa LL, Costa MC, Travassos AG et al: P16 (INK4A) expression as a potential prognostic marker in cervical pre-neoplastic and neoplastic lesions. Pathol Res Pract 202: 77-83, 2006.
35. Ögmundsdóttir HM, Björnsson J and Holbrook WP: Role of TP53 in the progression of pre-malignant and malignant oral mucosal lesions. A follow-up study of 144 patients. J Oral Pathol Med 38: 565-571, 2009.