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Volumn 68, Issue 11, 2010, Pages 2837-2845

Osteonecrosis of the jaw: Effect of bisphosphonate type, local concentration, and acidic milieu on the pathomechanism

Author keywords

[No Author keywords available]

Indexed keywords

CLODRONIC ACID; IBANDRONIC ACID; ZOLEDRONIC ACID;

EID: 77958530598     PISSN: 02782391     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joms.2010.07.017     Document Type: Article
Times cited : (122)

References (53)
  • 1
    • 0042861578 scopus 로고    scopus 로고
    • Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic
    • R.E. Marx Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic J Oral Maxillofac Surg 61 2003 1115
    • (2003) J Oral Maxillofac Surg , vol.61 , pp. 1115
    • Marx, R.E.1
  • 2
    • 0041358697 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws associated with cancer chemotherapy
    • J. Wang, N.M. Goodger, and M.A. Pogrel Osteonecrosis of the jaws associated with cancer chemotherapy J Oral Maxillofac Surg 61 2003 1104
    • (2003) J Oral Maxillofac Surg , vol.61 , pp. 1104
    • Wang, J.1    Goodger, N.M.2    Pogrel, M.A.3
  • 3
    • 0642316721 scopus 로고    scopus 로고
    • Bisphosphanates and oral cavity avascular bone necrosis
    • C.A. Migliorati Bisphosphanates and oral cavity avascular bone necrosis J Clin Oncol 21 2003 4253
    • (2003) J Clin Oncol , vol.21 , pp. 4253
    • Migliorati, C.A.1
  • 4
    • 34848841461 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research
    • S. Khosla, D. Burr, and J. Cauley Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research J Bone Miner Res 22 2007 1479
    • (2007) J Bone Miner Res , vol.22 , pp. 1479
    • Khosla, S.1    Burr, D.2    Cauley, J.3
  • 5
    • 64649105333 scopus 로고    scopus 로고
    • American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws2009 update
    • S.L. Ruggiero, T.B. Dodson, and L.A. Assael American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws2009 update J Oral Maxillofac Surg 67 2009 2
    • (2009) J Oral Maxillofac Surg , vol.67 , pp. 2
    • Ruggiero, S.L.1    Dodson, T.B.2    Assael, L.A.3
  • 6
    • 60249087667 scopus 로고    scopus 로고
    • The role of inferior alveolar nerve involvement in bisphosphonate-related osteonecrosis of the jaw
    • S. Otto, S. Hafner, and K.A. Grotz The role of inferior alveolar nerve involvement in bisphosphonate-related osteonecrosis of the jaw J Oral Maxillofac Surg 67 2009 589
    • (2009) J Oral Maxillofac Surg , vol.67 , pp. 589
    • Otto, S.1    Hafner, S.2    Grotz, K.A.3
  • 7
    • 39749174909 scopus 로고    scopus 로고
    • "Bis-phossy jaws"High and low risk factors for bisphosphonate-induced osteonecrosis of the jaw
    • M.H. Abu-Id, P.H. Warnke, and J. Gottschalk "Bis-phossy jaws"High and low risk factors for bisphosphonate-induced osteonecrosis of the jaw J Craniomaxillofac Surg 36 2008 95
    • (2008) J Craniomaxillofac Surg , vol.36 , pp. 95
    • Abu-Id, M.H.1    Warnke, P.H.2    Gottschalk, J.3
  • 8
    • 33644841755 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors
    • A. Bamias, E. Kastritis, and C. Bamia Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors J Clin Oncol 23 2005 8580
    • (2005) J Clin Oncol , vol.23 , pp. 8580
    • Bamias, A.1    Kastritis, E.2    Bamia, C.3
  • 9
    • 46149121940 scopus 로고    scopus 로고
    • Bisphosphonate-induced osteonecrosis of the jaws: Prospective study of 80 patients with multiple myeloma and other malignancies
    • T. Boonyapakorn, I. Schirmer, and P.A. Reichart Bisphosphonate-induced osteonecrosis of the jaws: Prospective study of 80 patients with multiple myeloma and other malignancies Oral Oncol 44 2008 857
    • (2008) Oral Oncol , vol.44 , pp. 857
    • Boonyapakorn, T.1    Schirmer, I.2    Reichart, P.A.3
  • 10
    • 55649090798 scopus 로고    scopus 로고
    • Prevalence and risk factors of bisphosphonate-associated osteonecrosis of the jaw in prostate cancer patients with advanced disease treated with zoledronate
    • C. Walter, B. Al-Nawas, and K.A. Grotz Prevalence and risk factors of bisphosphonate-associated osteonecrosis of the jaw in prostate cancer patients with advanced disease treated with zoledronate Eur Urol 54 2008 1066
    • (2008) Eur Urol , vol.54 , pp. 1066
    • Walter, C.1    Al-Nawas, B.2    Grotz, K.A.3
  • 11
    • 34250159241 scopus 로고    scopus 로고
    • Incidence of osteonecrosis of the jaw in patients with multiple myeloma and breast or prostate cancer on intravenous bisphosphonate therapy
    • E.P. Wang, L.B. Kaban, and G.J. Strewler Incidence of osteonecrosis of the jaw in patients with multiple myeloma and breast or prostate cancer on intravenous bisphosphonate therapy J Oral Maxillofac Surg 65 2007 1328
    • (2007) J Oral Maxillofac Surg , vol.65 , pp. 1328
    • Wang, E.P.1    Kaban, L.B.2    Strewler, G.J.3
  • 12
    • 58049204529 scopus 로고    scopus 로고
    • Natural history of osteonecrosis of the jaw in patients with multiple myeloma
    • A. Badros, E. Terpos, and E. Katodritou Natural history of osteonecrosis of the jaw in patients with multiple myeloma J Clin Oncol 26 2008 5904
    • (2008) J Clin Oncol , vol.26 , pp. 5904
    • Badros, A.1    Terpos, E.2    Katodritou, E.3
  • 13
    • 53749083356 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaws: A case-control study of risk factors in breast cancer patients
    • A. Kyrgidis, K. Vahtsevanos, and G. Koloutsos Bisphosphonate-related osteonecrosis of the jaws: A case-control study of risk factors in breast cancer patients J Clin Oncol 26 2008 4634
    • (2008) J Clin Oncol , vol.26 , pp. 4634
    • Kyrgidis, A.1    Vahtsevanos, K.2    Koloutsos, G.3
  • 14
    • 74249112988 scopus 로고    scopus 로고
    • Predicting risk of osteonecrosis of the jaw with oral Bisphosphonate Exposure (PROBE) Investigators: Prevalence of osteonecrosis of the jaw in patients with oral bisphosphonate exposure
    • J.C. Lo, F.S. O'Ryan, and N.P. Gordon Predicting risk of osteonecrosis of the jaw with oral Bisphosphonate Exposure (PROBE) Investigators Prevalence of osteonecrosis of the jaw in patients with oral bisphosphonate exposure J Oral Maxillofac Surg 68 2010 243
    • (2010) J Oral Maxillofac Surg , vol.68 , pp. 243
    • Lo, J.C.1    O'Ryan, F.S.2    Gordon, N.P.3
  • 15
    • 50949086241 scopus 로고    scopus 로고
    • Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling
    • M.M. McDonald, S. Dulai, and C. Godfrey Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling Bone 43 2008 653
    • (2008) Bone , vol.43 , pp. 653
    • McDonald, M.M.1    Dulai, S.2    Godfrey, C.3
  • 16
    • 58249087710 scopus 로고    scopus 로고
    • Giant osteoclast formation and long-term oral bisphosphonate therapy
    • R.S. Weinstein, P.K. Roberson, and S.C. Manolagas Giant osteoclast formation and long-term oral bisphosphonate therapy N Engl J Med 360 2009 53
    • (2009) N Engl J Med , vol.360 , pp. 53
    • Weinstein, R.S.1    Roberson, P.K.2    Manolagas, S.C.3
  • 17
    • 34547612321 scopus 로고    scopus 로고
    • Is bisphosphonate-associated osteonecrosis of the jaw caused by soft tissue toxicity?
    • I.R. Reid, M.J. Bolland, and A.B. Grey Is bisphosphonate-associated osteonecrosis of the jaw caused by soft tissue toxicity? Bone 41 2007 318
    • (2007) Bone , vol.41 , pp. 318
    • Reid, I.R.1    Bolland, M.J.2    Grey, A.B.3
  • 18
    • 42149184112 scopus 로고    scopus 로고
    • Inhibition of oral mucosal cell wound healing by bisphosphonates
    • R. Landesberg, M. Cozin, and S. Cremers Inhibition of oral mucosal cell wound healing by bisphosphonates J Oral Maxillofac Surg 66 2008 839
    • (2008) J Oral Maxillofac Surg , vol.66 , pp. 839
    • Landesberg, R.1    Cozin, M.2    Cremers, S.3
  • 19
    • 53549122453 scopus 로고    scopus 로고
    • Effects of risedronate on alveolar bone loss and angiogenesis: A stereologic study in rats
    • B.O. Cetinkaya, G.C. Keles, and B. Ayas Effects of risedronate on alveolar bone loss and angiogenesis: A stereologic study in rats J Periodontol 79 2008 1950
    • (2008) J Periodontol , vol.79 , pp. 1950
    • Cetinkaya, B.O.1    Keles, G.C.2    Ayas, B.3
  • 20
    • 0036000591 scopus 로고    scopus 로고
    • Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice
    • M.M. Deckers, E.R. Van Beek, and G. Van Der Pluijm Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice J Bone Miner Res 17 2002 998
    • (2002) J Bone Miner Res , vol.17 , pp. 998
    • Deckers, M.M.1    Van Beek, E.R.2    Van Der Pluijm, G.3
  • 21
    • 33645229970 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws in patients treated with bisphosphonatesHistomorphologic analysis in comparison with infected osteoradionecrosis
    • T. Hansen, M. Kunkel, and A. Weber Osteonecrosis of the jaws in patients treated with bisphosphonatesHistomorphologic analysis in comparison with infected osteoradionecrosis J Oral Pathol Med 35 2006 155
    • (2006) J Oral Pathol Med , vol.35 , pp. 155
    • Hansen, T.1    Kunkel, M.2    Weber, A.3
  • 22
    • 33748804427 scopus 로고    scopus 로고
    • The effect of zoledronic acid on the function and differentiation of myeloid cells
    • A.M. Wolf, H. Rumpold, and H. Tilg The effect of zoledronic acid on the function and differentiation of myeloid cells Haematologica 91 2006 1165
    • (2006) Haematologica , vol.91 , pp. 1165
    • Wolf, A.M.1    Rumpold, H.2    Tilg, H.3
  • 23
    • 58149086028 scopus 로고    scopus 로고
    • Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP
    • A.J. Roelofs, M. Jauhiainen, and H. Monkkonen Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP Br J Haematol 144 2009 245
    • (2009) Br J Haematol , vol.144 , pp. 245
    • Roelofs, A.J.1    Jauhiainen, M.2    Monkkonen, H.3
  • 24
    • 77950809933 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaw: Is pH the missing part in the pathogenesis puzzle?
    • S. Otto, S. Hafner, and G. Mast Bisphosphonate-related osteonecrosis of the jaw: Is pH the missing part in the pathogenesis puzzle? J Oral Maxillofac Surg 68 2010 1158
    • (2010) J Oral Maxillofac Surg , vol.68 , pp. 1158
    • Otto, S.1    Hafner, S.2    Mast, G.3
  • 25
    • 43049109229 scopus 로고    scopus 로고
    • Mechanisms of action of bisphosphonates: Similarities and differences and their potential influence on clinical efficacy
    • R.G. Russell, N.B. Watts, and F.H. Ebetino Mechanisms of action of bisphosphonates: Similarities and differences and their potential influence on clinical efficacy Osteoporos Int 19 2008 733
    • (2008) Osteoporos Int , vol.19 , pp. 733
    • Russell, R.G.1    Watts, N.B.2    Ebetino, F.H.3
  • 26
    • 41949097526 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw and bisphosphonate treatment for osteoporosis
    • R. Rizzoli, N. Burlet, and D. Cahall Osteonecrosis of the jaw and bisphosphonate treatment for osteoporosis Bone 42 2008 841
    • (2008) Bone , vol.42 , pp. 841
    • Rizzoli, R.1    Burlet, N.2    Cahall, D.3
  • 27
    • 33847284113 scopus 로고    scopus 로고
    • American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws
    • Advisory Task Force on Bisphosphonate-Related Ostenonecrosis of the Jaws, American Association of Oral and Maxillofacial Surgeons
    • Advisory Task Force on Bisphosphonate-Related Ostenonecrosis of the Jaws, American Association of Oral and Maxillofacial Surgeons American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws J Oral Maxillofac Surg 65 2007 369
    • (2007) J Oral Maxillofac Surg , vol.65 , pp. 369
  • 28
    • 52549118412 scopus 로고    scopus 로고
    • IKK-2 is required for TNF-alpha-induced invasion and proliferation of human mesenchymal stem cells
    • W. Bocker, D. Docheva, and W.C. Prall IKK-2 is required for TNF-alpha-induced invasion and proliferation of human mesenchymal stem cells J Mol Med 86 2008 1183
    • (2008) J Mol Med , vol.86 , pp. 1183
    • Bocker, W.1    Docheva, D.2    Prall, W.C.3
  • 29
    • 46749130481 scopus 로고    scopus 로고
    • Ibandronate uptake in the jaw is similar to long bones and vertebrae in the rat
    • F. Bauss, T. Pfister, and S. Papapoulos Ibandronate uptake in the jaw is similar to long bones and vertebrae in the rat J Bone Miner Metab 26 2008 406
    • (2008) J Bone Miner Metab , vol.26 , pp. 406
    • Bauss, F.1    Pfister, T.2    Papapoulos, S.3
  • 30
    • 33646089442 scopus 로고    scopus 로고
    • Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite
    • G.H. Nancollas, R. Tang, and R.J. Phipps Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite Bone 38 2006 617
    • (2006) Bone , vol.38 , pp. 617
    • Nancollas, G.H.1    Tang, R.2    Phipps, R.J.3
  • 31
    • 33646080124 scopus 로고    scopus 로고
    • Relative binding affinities of bisphosphonates for human bone and relationship to antiresorptive efficacy
    • C.T. Leu, E. Luegmayr, and L.P. Freedman Relative binding affinities of bisphosphonates for human bone and relationship to antiresorptive efficacy Bone 38 2006 628
    • (2006) Bone , vol.38 , pp. 628
    • Leu, C.T.1    Luegmayr, E.2    Freedman, L.P.3
  • 32
    • 3042643207 scopus 로고    scopus 로고
    • Ibandronate in osteoporosis: Preclinical data and rationale for intermittent dosing
    • F. Bauss, and R.G. Russell Ibandronate in osteoporosis: Preclinical data and rationale for intermittent dosing Osteoporos Int 15 2004 423
    • (2004) Osteoporos Int , vol.15 , pp. 423
    • Bauss, F.1    Russell, R.G.2
  • 33
    • 48749109057 scopus 로고    scopus 로고
    • Hypoxia in static and dynamic 3D culture systems for tissue engineering of bone
    • E. Volkmer, I. Drosse, and S. Otto Hypoxia in static and dynamic 3D culture systems for tissue engineering of bone Tissues Eng A 14 2008 1331
    • (2008) Tissues Eng A , vol.14 , pp. 1331
    • Volkmer, E.1    Drosse, I.2    Otto, S.3
  • 34
    • 75849147619 scopus 로고    scopus 로고
    • Influence of bisphosphonates on endothelial cells, fibroblasts, and osteogenic cells
    • C. Walter, M.O. Klein, and A. Pabst Influence of bisphosphonates on endothelial cells, fibroblasts, and osteogenic cells Clin Oral Investig 14 2010 35
    • (2010) Clin Oral Investig , vol.14 , pp. 35
    • Walter, C.1    Klein, M.O.2    Pabst, A.3
  • 35
    • 41949138597 scopus 로고    scopus 로고
    • Preclinical evidence for nitrogen-containing bisphosphonate inhibition of farnesyl diphosphate (FPP) synthase in the kidney: Implications for renal safety
    • A. Luhe, K.P. Kunkele, and M. Haiker Preclinical evidence for nitrogen-containing bisphosphonate inhibition of farnesyl diphosphate (FPP) synthase in the kidney: Implications for renal safety Toxicol Vitro 22 2008 899
    • (2008) Toxicol Vitro , vol.22 , pp. 899
    • Luhe, A.1    Kunkele, K.P.2    Haiker, M.3
  • 36
    • 0028842688 scopus 로고
    • Inhibition of antigen-presenting cell function by alendronate in vitro
    • P. Sansoni, G. Passeri, and F. Fagnoni Inhibition of antigen-presenting cell function by alendronate in vitro J Bone Miner Res 10 1995 1719
    • (1995) J Bone Miner Res , vol.10 , pp. 1719
    • Sansoni, P.1    Passeri, G.2    Fagnoni, F.3
  • 37
    • 57149098821 scopus 로고    scopus 로고
    • Anti-angiogenic property of zoledronic acid by inhibition of endothelial progenitor cell differentiation
    • J. Yamada, N.H. Tsuno, and J. Kitayama Anti-angiogenic property of zoledronic acid by inhibition of endothelial progenitor cell differentiation J Surg Res 151 2009 115
    • (2009) J Surg Res , vol.151 , pp. 115
    • Yamada, J.1    Tsuno, N.H.2    Kitayama, J.3
  • 38
    • 38449112480 scopus 로고    scopus 로고
    • Alendronate has an anabolic effect on bone through the differentiation of mesenchymal stem cells
    • G. Duque, and D. Rivas Alendronate has an anabolic effect on bone through the differentiation of mesenchymal stem cells J Bone Miner Res 22 2007 1603
    • (2007) J Bone Miner Res , vol.22 , pp. 1603
    • Duque, G.1    Rivas, D.2
  • 39
    • 66049130260 scopus 로고    scopus 로고
    • In-vitro osteogenesis of synovium stem cells induced by controlled release of bisphosphate additives from microspherical mesoporous silica composite
    • X. Shi, Y. Wang, and R.R. Varshney In-vitro osteogenesis of synovium stem cells induced by controlled release of bisphosphate additives from microspherical mesoporous silica composite Biomaterials 30 2009 3996
    • (2009) Biomaterials , vol.30 , pp. 3996
    • Shi, X.1    Wang, Y.2    Varshney, R.R.3
  • 40
    • 33644906138 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in multiple myeloma patients: Clinical features and risk factors
    • A. Badros, D. Weikel, and A. Salama Osteonecrosis of the jaw in multiple myeloma patients: Clinical features and risk factors J Clin Oncol 24 2006 945
    • (2006) J Clin Oncol , vol.24 , pp. 945
    • Badros, A.1    Weikel, D.2    Salama, A.3
  • 41
    • 0018876986 scopus 로고
    • Dynamic histomorphometry of alveolar bone remodeling in the adult rat
    • A. Vignery, and R. Baron Dynamic histomorphometry of alveolar bone remodeling in the adult rat Anat Rec 196 1980 191
    • (1980) Anat Rec , vol.196 , pp. 191
    • Vignery, A.1    Baron, R.2
  • 45
  • 46
    • 0031440055 scopus 로고    scopus 로고
    • Artificial pressure increase in subcutaneous abscess with evidence of general systemic reaction
    • P. Bertram, K.H. Treutner, and B. Klosterhalfen [Artificial pressure increase in subcutaneous abscess with evidence of general systemic reaction] Langenbecks Arch Chir 382 1997 291
    • (1997) Langenbecks Arch Chir , vol.382 , pp. 291
    • Bertram, P.1    Treutner, K.H.2    Klosterhalfen, B.3
  • 47
    • 0028047585 scopus 로고
    • Electrolyte concentration, real and osmotic pressure in abscesses
    • K.G. Wiese [Electrolyte concentration, real and osmotic pressure in abscesses] Zentralbl Chir 119 1994 54
    • (1994) Zentralbl Chir , vol.119 , pp. 54
    • Wiese, K.G.1
  • 48
    • 44449153039 scopus 로고    scopus 로고
    • Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates
    • A.O. Hoff, B.B. Toth, and K. Altundag Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates J Bone Miner Res 23 2008 826
    • (2008) J Bone Miner Res , vol.23 , pp. 826
    • Hoff, A.O.1    Toth, B.B.2    Altundag, K.3
  • 49
    • 43749089576 scopus 로고    scopus 로고
    • Factors associated with osteonecrosis of the jaw among bisphosphonate users
    • L.M. Hess, J.M. Jeter, and M. Benham-Hutchins Factors associated with osteonecrosis of the jaw among bisphosphonate users Am J Med 121 2008 475
    • (2008) Am J Med , vol.121 , pp. 475
    • Hess, L.M.1    Jeter, J.M.2    Benham-Hutchins, M.3
  • 50
    • 58949104001 scopus 로고    scopus 로고
    • Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid
    • M.A. Dimopoulos, E. Kastritis, and C. Bamia Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid Ann Oncol 20 2009 117
    • (2009) Ann Oncol , vol.20 , pp. 117
    • Dimopoulos, M.A.1    Kastritis, E.2    Bamia, C.3
  • 51
    • 0026320852 scopus 로고
    • Bisphosphonate action: Alendronate localization in rat bone and effects on osteoclast ultrastructure
    • M. Sato, W. Grasser, and N. Endo Bisphosphonate action: Alendronate localization in rat bone and effects on osteoclast ultrastructure J Clin Invest 88 1991 2095
    • (1991) J Clin Invest , vol.88 , pp. 2095
    • Sato, M.1    Grasser, W.2    Endo, N.3
  • 52
    • 70349412921 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: A key role of inflammation?
    • P. Lesclous, S.A. Najm, and J.P. Carrel Bisphosphonate-associated osteonecrosis of the jaw: A key role of inflammation? Bone 45 2009 843
    • (2009) Bone , vol.45 , pp. 843
    • Lesclous, P.1    Najm, S.A.2    Carrel, J.P.3
  • 53
    • 0034659773 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of action of bisphosphonates
    • M.J. Rogers, S. Gordon, and H.L. Benford Cellular and molecular mechanisms of action of bisphosphonates Cancer 88 2000 2961
    • (2000) Cancer , vol.88 , pp. 2961
    • Rogers, M.J.1    Gordon, S.2    Benford, H.L.3


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