Proinflammatory and proadhesive activation of lymphocytes and macrophages in sudden sensorineural hearing loss

Audiology and Neurotology

Volumn 16, Issue 4, 2011, Pages 254-262

  Kassner, Stefan S ^a   Schöttler, Sarah ^a   Bonaterra, Gabriel A ^b   Stern Sträter, Jens ^a   Sommer, Ulrich ^a   Hormann, Karl ^a   Kinscherf, Ralf ^b   Gössler, Ulrich R ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Anatomy and Cell Biology Department of Medical Cell Biology ^*  (Germany)

Author keywords

Adhesion; CD38; CD40; Inflammation; Lymphocytes; Peripheral blood mononuclear cell; Sudden hearing loss

Indexed keywords

LEUKOCYTE ANTIGEN;

ADOLESCENT; ADULT; ARTICLE; CELL ADHESION; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; LYMPHOCYTE; LYMPHOCYTE COUNT; MACROPHAGE; MALE; METABOLISM; MIDDLE AGED; SUDDEN DEAFNESS;

ADOLESCENT; ADULT; ANTIGENS, CD; CELL ADHESION; FEMALE; FLOW CYTOMETRY; HEARING LOSS, SUDDEN; HUMANS; LYMPHOCYTE COUNT; LYMPHOCYTES; MACROPHAGES; MALE; MIDDLE AGED;

EID: 77958489858     PISSN: 14203030     EISSN: 14219700     Source Type: Journal    
DOI: 10.1159/000320610     Document Type: Article

References (45)

1. Alderson MR, Armitage RJ, Tough TW, Strockbine L, Fanslow WC, Spriggs MK: CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40. J Exp Med 1993; 178: 669-674.
2. Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, Harley JB: Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003; 349: 1526-1533.
3. Berg-Brown NN, Gronski MA, Jones RG, Elford AR, Deenick EK, Odermatt B, Littman DR, Ohashi PS: PKCtheta signals activation versus tolerance in vivo. J Exp Med 2004; 199: 743-752.
4. Bonaterra GA, Hildebrandt W, Bodens A, Sauer R, Dugi KA, Deigner HP, Droge W, Metz J, Kinscherf R: Increased cyclooxygenase-2 expression in peripheral blood mononuclear cells of smokers and hyperlipidemic subjects. Free Radic Biol Med 2005; 38: 235-242.
5. Bonaterra GA, Hildebrandt W, Bodens A, Sauer R, Dugi KA, Deigner HP, Turcanu D, Heinle H, Droge W, Metz J, Kinscherf R: Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males. J Mol Med 2007; 85: 181-190.
6. Brookes GB: Immune complex-associated deafness: preliminary communication. J R Soc Med 1985; 78: 47-55.
7. Byl FM Jr: Sudden hearing loss: eight years' experience and suggested prognostic table. Laryngoscope 1984; 94: 647-661.
8. Deaglio S, Morra M, Mallone R, Ausiello CM, Prager E, Garbarino G, Dianzani U, Stockinger H, Malavasi F: Human CD38 (ADPribosyl cyclase) is a counter-receptor of CD31, an Ig superfamily member. J Immunol 1998; 160: 395-402.
9. Desai-Mehta A, Lu L, Ramsey-Goldman R, Datta SK: Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production. J Clin Invest 1996; 97: 2063-2073.
10. Dianzani U, Funaro A, DiFranco D, Garbarino G, Bragardo M, Redoglia V, Buonfiglio D, De Monte LB, Pileri A, Malavasi F: Interaction between endothelium and CD4+CD45RA+ lymphocytes: role of the human CD38 molecule. J Immunol 1994; 153: 952-959.
11. Garcia Berrocal JR, Ramirez-Camacho R: Immune response and immunopathology of the inner ear: an update. J Laryngol Otol 2000; 114: 101-107.
12. Garcia-Berrocal JR, Vargas JA, Ramirez-Camacho RA, Gonzalez FM, Gea-Banacloche JC, Vergara J, Durantez A: Deficiency of naive T cells in patients with sudden deafness. Arch Otolaryngol Head Neck Surg 1997; 123: 712-717.
13. Gloddek B, Ryan AF, Harris JP: Homing of lymphocytes to the inner ear. Acta Otolaryngol 1991; 111: 1051-1059.
14. Harris JP, Woolf NK, Ryan AF: Elaboration of systemic immunity following inner ear immunization. Am J Otolaryngol 1985; 6: 148-152.
15. Heinrich UR, Brieger J, Selivanova O, Feltens R, Eimermacher A, Schafer D, Mann WJ: COX- 2 expression in the guinea pig cochlea is partly altered by moderate sound exposure. Neurosci Lett 2006; 394: 121-126.
16. Henn V, Slupsky JR, Grafe M, Anagnostopoulos I, Forster R, Muller-Berghaus G, Kroczek RA: CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature 1998; 391: 591-594.
17. Ichimiya I, Kurono Y, Hirano T, Mogi G: Changes in immunostaining of inner ears after antigen challenge into the scala tympani. Laryngoscope 1998;108:585-591.
18. Iwai H, Tomoda K, Sugiura K, Inaba M, Ikehara S, Yamashita T: T cells infiltrating from the systemic circulation proliferate in the endolymphatic sac. Ann Otol Rhinol Laryngol 1999; 108: 1146-1150.
19. Kassner S, Kollmar R, Bonaterra G, Hildebrandt W, Schwab S, Kinscherf R: The early immunological response to acute ischemic stroke: differential gene expression in subpopulations of mononuclear cells. Neuroscience 2009; 160: 394-401.
20. Kassner SS, Bonaterra GA, Kaiser E, Hildebrandt W, Metz J, Schroder J, Kinscherf R: Novel systemic markers for patients with Alzheimer disease? - A pilot study. Curr Alzheimer Res 2008; 5: 358-366.
21. Keithley EM, Woolf NK, Harris JP: Development of morphological and physiological changes in the cochlea induced by cytomegalovirus. Laryngoscope 1989; 99: 409-414.
22. Kline MW, Frasch CE: Sudden-onset deafness: serodiagnosis of recent meningococcal infection. Clin Pediatr (Phila) 1989; 28: 529-532.
23. McCabe BF: Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol 1979; 88: 585-589.
24. Merchant SN, Adams JC, Nadol JB Jr: Pathology and pathophysiology of idiopathic sudden sensorineural hearing loss. Otol Neurotol 2005; 26: 151-160.
25. Merchant SN, Durand ML, Adams JC: Sudden deafness: is it viral? ORL J Otorhinolaryngol Relat Spec 2008; 70: 52-60; discussion 60-62.
26. Monaco C, Andreakos E, Young S, Feldmann M, Paleolog E: T cell-mediated signaling to vascular endothelium: induction of cytokines, chemokines, and tissue factor. J Leukoc Biol 2002; 71: 659-668.
27. Muller WA, Weigl SA, Deng X, Phillips DM: Pecam-1 is required for transendothelial migration of leukocytes. J Exp Med 1993; 178: 449-460.
28. Omari KM, Dorovini-Zis K: CD40 expressed by human brain endothelial cells regulates CD4+ T cell adhesion to endothelium. J Neuroimmunol 2003; 134: 166-178.
29. Phipps RP: Atherosclerosis: the emerging role of inflammation and the CD40-CD40 ligand system. Proc Natl Acad Sci USA 2000; 97: 6930-6932.
30. Rauch SD: Clinical practice: idiopathic sudden sensorineural hearing loss. N Engl J Med 2008; 359: 833-840.
31. Ryan AF, Harris JP, Keithley EM: Immune-mediated hearing loss: basic mechanisms and options for therapy. Acta Otolaryngol Suppl 2002: 38-43.
32. Simmons FB: The double-membrane break syndrome in sudden hearing loss. Laryngoscope 1979; 89: 59-66.
33. Stearns GS, Keithley EM, Harris JP: Development of high endothelial venule-like characteristics in the spiral modiolar vein induced by viral labyrinthitis. Laryngoscope 1993; 103: 890-898.
34. Takumida M, Anniko M: Localization of endotoxin in the inner ear following inoculation into the middle ear. Acta Otolaryngol 2004; 124: 772-777.
35. Thienel U, Loike J, Yellin MJ: CD154 (CD40l) induces human endothelial cell chemokine production and migration of leukocyte subsets. Cell Immunol 1999; 198: 87-95.
36. Tomiyama S, Harris JP: The role of the endolymphatic sac in inner ear immunity. Acta Otolaryngol 1987; 103: 182-188.
37. Tomiyama S, Jinnouchi K, Ikezono T, Pawankar R, Yagi T: Experimental autoimmune labyrinthitis induced by cell-mediated immune reaction. Acta Otolaryngol 1999; 119: 665-670.
38. Van Kooten C, Banchereau J: CD40-CD40 ligand. J Leukoc Biol 2000; 67: 2-17.
39. Veldman JE: Immune-mediated sensorineural hearing loss with or without endolymphatic hydrops: a clinical and experimental approach. Ann NY Acad Sci 1997; 830: 179-186.
40. Wilson WR, Byl FM, Laird N: The efficacy of steroids in the treatment of idiopathic sudden hearing loss: a double-blind clinical study. Arch Otolaryngol 1980; 106: 772-776.
41. Woolf NK, Harris JP: Cochlear pathophysiology associated with inner ear immune responses. Acta Otolaryngol 1986; 102: 353-364.
42. Xu L, Zhang L, Yi Y, Kang HK, Datta SK: Human lupus T cells resist inactivation and escape death by upregulating COX-2. Nat Med 2004; 10: 411-415.
43. Yamamoto K, Arakawa T, Ueda N, Yamamoto S: Transcriptional roles of nuclear factor κB and nuclear factor-interleukin-6 in the tumor necrosis factor α-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells. J Biol Chem 1995; 270: 31315-31320.
44. Yamasoba T, Kikuchi S, Higo R, O'Uchi T, Tokumaru A: Sudden sensorineural hearing loss associated with slow blood flow of the vertebrobasilar system. Ann Otol Rhinol Laryngol 1993; 102: 873-877.
45. Zheng Y, Vig M, Lyons J, Van Parijs L, Beg AA: Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor κB in regulating mature T cell survival and in vivo function. J Exp Med 2003; 197: 861-874.