-
1
-
-
1842476125
-
Co-occurrence of 12-month alcohol and drug use disorders and personality disorders in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions
-
Grant BF, Stinson FS, Dawson DA, et al. Co-occurrence of 12-month alcohol and drug use disorders and personality disorders in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry 2004;61:361-8
-
(2004)
Arch Gen Psychiatry
, vol.61
, pp. 361-8
-
-
Grant, B.F.1
Stinson, F.S.2
Dawson, D.A.3
-
2
-
-
20344374645
-
Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication
-
Kessler RC, Chiu WT, Demler O, et al. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005;62:617-27
-
(2005)
Arch Gen Psychiatry
, vol.62
, pp. 617-27
-
-
Kessler, R.C.1
Chiu, W.T.2
Demler, O.3
-
3
-
-
33646174681
-
Currently active and remitted alcohol dependence in a nationwide adult general population-results from the Finnish Health 2000 study
-
Pirkola SP, Poikolainen K, Lonnqvist JK. Currently active and remitted alcohol dependence in a nationwide adult general population-results from the Finnish Health 2000 study. Alcohol Alcohol 2006;41:315-20
-
(2006)
Alcohol Alcohol
, vol.41
, pp. 315-20
-
-
Pirkola, S.P.1
Poikolainen, K.2
Lonnqvist, J.K.3
-
4
-
-
19844371837
-
Alcohol use disorders in EU countries and Norway: An overview of the epidemiology
-
Rehm J, Room R, van den Brink W, Jacobi F. Alcohol use disorders in EU countries and Norway: an overview of the epidemiology. Eur Neuropsychopharmacol 2005;15:377-88
-
(2005)
Eur Neuropsychopharmacol
, vol.15
, pp. 377-88
-
-
Rehm, J.1
Room, R.2
Van Den Brink, W.3
Jacobi, F.4
-
6
-
-
39149099789
-
World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of substance use and related disorders, part 1: Alcoholism
-
Soyka M, Kranzler HR, Berglund M, et al. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of substance use and related disorders, part 1: alcoholism. World J Biol Psychiatry 2008;9:6-23
-
(2008)
World J Biol Psychiatry
, vol.9
, pp. 6-23
-
-
Soyka, M.1
Kranzler, H.R.2
Berglund, M.3
-
7
-
-
33746325472
-
Pharmacological treatment of alcohol dependence: Target symptoms and target mechanisms
-
Heilig M, Egli M. Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacol Ther 2006;111:855-76
-
(2006)
Pharmacol Ther
, vol.111
, pp. 855-76
-
-
Heilig, M.1
Egli, M.2
-
8
-
-
39749088094
-
Drugs for relapse prevention of alcoholism: Ten years of progress
-
Spanagel R, Kiefer F. Drugs for relapse prevention of alcoholism: ten years of progress. Trends Pharmacol Sci 2008;29:109-15
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 109-15
-
-
Spanagel, R.1
Kiefer, F.2
-
9
-
-
77958479285
-
Emerging drugs to treat alcoholism
-
published online 19 June 2010. doi:10.1517/14728214.2010.500811
-
Soyka M, Rosner S. Emerging drugs to treat alcoholism. Expert Opin Emerg Drugs 2010: published online 19 June 2010. doi:10.1517/14728214.2010.500811
-
(2010)
Expert Opin Emerg Drugs
-
-
Soyka, M.1
Rosner, S.2
-
10
-
-
37749032186
-
Acamprosate supports abstinence, naltrexone prevents excessive drinking: Evidence from a meta-analysis with unreported outcomes
-
Rosner S, Leucht S, Lehert P, Soyka M. Acamprosate supports abstinence, naltrexone prevents excessive drinking: evidence from a meta-analysis with unreported outcomes. J Psychopharmacol 2008;22:11-23
-
(2008)
J Psychopharmacol
, vol.22
, pp. 11-23
-
-
Rosner, S.1
Leucht, S.2
Lehert, P.3
Soyka, M.4
-
11
-
-
0038587675
-
Pharmacological mechanisms of naltrexone and acamprosate in the prevention of relapse in alcohol dependence
-
Littleton J, Zieglgansberger W. Pharmacological mechanisms of naltrexone and acamprosate in the prevention of relapse in alcohol dependence. Am J Addict 2003;12(Suppl 1):3-11
-
(2003)
Am J Addict
, vol.12
, Issue.SUPPL. 1
, pp. 3-11
-
-
Littleton, J.1
Zieglgansberger, W.2
-
12
-
-
0036710854
-
Effect of selective blockade of mu1 or delta opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats
-
Ciccocioppo R, Martin-Fardon R, Weiss F. Effect of selective blockade of mu1 or delta opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats. Neuropsychopharmacology 2002;27:391-9
-
(2002)
Neuropsychopharmacology
, vol.27
, pp. 391-9
-
-
Ciccocioppo, R.1
Martin-Fardon, R.2
Weiss, F.3
-
13
-
-
0033212713
-
The role of opioid-dopamine interactions in the induction and maintenance of ethanol consumption
-
Cowen MS, Lawrence AJ. The role of opioid-dopamine interactions in the induction and maintenance of ethanol consumption. Prog Neuropsychopharmacol Biol Psychiatry 1999;23:1171-212
-
(1999)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.23
, pp. 1171-212
-
-
Cowen, M.S.1
Lawrence, A.J.2
-
14
-
-
2142817953
-
Endogenous opioids and addiction to alcohol and other drugs of abuse
-
Gianoulakis C. Endogenous opioids and addiction to alcohol and other drugs of abuse. Curr Top Med Chem 2004;4:39-50
-
(2004)
Curr Top Med Chem
, vol.4
, pp. 39-50
-
-
Gianoulakis, C.1
-
15
-
-
0031037561
-
Endogenous opioid systems and alcohol addiction
-
HerzA. Endogenous opioid systems and alcohol addiction. Psychopharmacology (Berl) 1997;129:99-111
-
(1997)
Psychopharmacology (Berl)
, vol.129
, pp. 99-111
-
-
Herz, A.1
-
16
-
-
0026507628
-
Drugs of abuse: Anatomy, pharmacology and function of reward pathways
-
Koob GF. Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends Pharmacol Sci 1992;13:177-84
-
(1992)
Trends Pharmacol Sci
, vol.13
, pp. 177-84
-
-
Koob, G.F.1
-
18
-
-
77958505079
-
Psychische Storungen und Verhaltensstorungen durch psychotrope Substanzen-Opiate [Mental disorders and behavioural disorders caused by psychotropic substances-opiates (authors' translation)]
-
Benkert O, Grunder G, editors Springer Verlag, Berlin
-
Scherbaum N, Davids E, Gastpar M. Psychische Storungen und Verhaltensstorungen durch psychotrope Substanzen-Opiate [Mental disorders and behavioural disorders caused by psychotropic substances-opiates (authors' translation)]. In: Benkert O, Grunder G, editors, Psychiatrische pharmakotherapie. 5th edition. Springer Verlag, Berlin; 2008. p. 804-14
-
(2008)
Psychiatrische Pharmakotherapie. 5th Edition.
, pp. 804-14
-
-
Scherbaum, N.1
Davids, E.2
Gastpar, M.3
-
19
-
-
13244298667
-
Are mu-opioid receptor polymorphisms important for clinical opioid therapy?
-
Lotsch J, Geisslinger G. Are mu-opioid receptor polymorphisms important for clinical opioid therapy? Trends Mol Med 2005;11:82-9
-
(2005)
Trends Mol Med
, vol.11
, pp. 82-9
-
-
Lotsch, J.1
Geisslinger, G.2
-
21
-
-
13144261678
-
Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction
-
Bond C, LaForge KS, Tian M, et al. Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci USA 1998;95:9608-13
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9608-13
-
-
Bond, C.1
Laforge, K.S.2
Tian, M.3
-
22
-
-
33847704911
-
Association of a functional polymorphism in the mu-opioid receptor gene with alcohol response and consumption in male rhesus macaques
-
Barr CS, Schwandt M, Lindell SG, et al. Association of a functional polymorphism in the mu-opioid receptor gene with alcohol response and consumption in male rhesus macaques. Arch Gen Psychiatry 2007;64:369-76
-
(2007)
Arch Gen Psychiatry
, vol.64
, pp. 369-76
-
-
Barr, C.S.1
Schwandt, M.2
Lindell, S.G.3
-
23
-
-
12344265724
-
Increased attributable risk related to a functional μ-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden
-
Bart G, Kreek MJ, Ott J, et al. Increased attributable risk related to a functional μ-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. Neuropsychopharmacology 2005;30:417-22
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 417-22
-
-
Bart, G.1
Kreek, M.J.2
Ott, J.3
-
24
-
-
33947289675
-
Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: Results from the VA Cooperative Study
-
Gelernter J, Gueorguieva R, Kranzler HR, et al. Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study. Alcohol Clin Exp Res 2007;31:555-63
-
(2007)
Alcohol Clin Exp Res
, vol.31
, pp. 555-63
-
-
Gelernter, J.1
Gueorguieva, R.2
Kranzler, H.R.3
-
25
-
-
34548147088
-
Mu (μ) opioid receptor regulation of ethanol-induced dopamine response in the ventral striatum: Evidence of genotype specific sexual dimorphic epistasis
-
Job MO, Tang A, Hall FS, et al. Mu (μ) opioid receptor regulation of ethanol-induced dopamine response in the ventral striatum: evidence of genotype specific sexual dimorphic epistasis. Biol Psychiatry 2007;62:627-34
-
(2007)
Biol Psychiatry
, vol.62
, pp. 627-34
-
-
Job, M.O.1
Tang, A.2
Hall, F.S.3
-
26
-
-
33744957486
-
Association of mu-opioid receptor gene polymorphism A118G with alcohol dependence in a Japanese population
-
Nishizawa D, Han W, Hasegawa J, et al. Association of mu-opioid receptor gene polymorphism A118G with alcohol dependence in a Japanese population. Neuropsychobiology 2006;53:137-41
-
(2006)
Neuropsychobiology
, vol.53
, pp. 137-41
-
-
Nishizawa, D.1
Han, W.2
Hasegawa, J.3
-
27
-
-
33845864182
-
A functional polymorphism of the mu-opioid receptor gene (OPRM1) influences cue-induced craving for alcohol in male heavy drinkers
-
van den Wildenberg E, Wiers RW, Dessers J, et al. A functional polymorphism of the mu-opioid receptor gene (OPRM1) influences cue-induced craving for alcohol in male heavy drinkers. Alcohol Clin Exp Res 2007;31:1-10
-
(2007)
Alcohol Clin Exp Res
, vol.31
, pp. 1-10
-
-
Van Den Wildenberg, E.1
Wiers, R.W.2
Dessers, J.3
-
28
-
-
33750319817
-
Association of the kappa-opioid system with alcohol dependence
-
Xuei X, Dick D, Flury-Wetherill L, et al. Association of the kappa-opioid system with alcohol dependence. Mol Psychiatry 2006;11:1016-24
-
(2006)
Mol Psychiatry
, vol.11
, pp. 1016-24
-
-
Xuei, X.1
Dick, D.2
Flury-Wetherill, L.3
-
29
-
-
33746349505
-
Genetic moderators of naltrexone's effects on alcohol cue reactivity
-
McGeary JE, Monti PM, Rohsenow DJ, et al. Genetic moderators of naltrexone's effects on alcohol cue reactivity. Alcohol Clin Exp Res 2006;30:1288-96
-
(2006)
Alcohol Clin Exp Res
, vol.30
, pp. 1288-96
-
-
McGeary, J.E.1
Monti, P.M.2
Rohsenow, D.J.3
-
30
-
-
60649107477
-
OPRM1 Asn40Asp predicts response to naltrexone treatment: A haplotype-based approach
-
Oroszi G, Anton RF, O'Malley S, et al. OPRM1 Asn40Asp predicts response to naltrexone treatment: a haplotype-based approach. Alcohol Clin Exp Res 2009;33:383-93
-
(2009)
Alcohol Clin Exp Res
, vol.33
, pp. 383-93
-
-
Oroszi, G.1
Anton, R.F.2
O'Malley, S.3
-
31
-
-
0041383898
-
A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients
-
Oslin DW, Berrettini W, Kranzler HR, et al. A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology 2003;28:1546-52
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 1546-52
-
-
Oslin, D.W.1
Berrettini, W.2
Kranzler, H.R.3
-
32
-
-
38949103745
-
An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: Results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study
-
Anton RF, Oroszi G, O'Malley S, et al. An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Arch Gen Psychiatry 2008;65:135-44
-
(2008)
Arch Gen Psychiatry
, vol.65
, pp. 135-44
-
-
Anton, R.F.1
Oroszi, G.2
O'Malley, S.3
-
33
-
-
57049180262
-
A mu opioid receptor gene polymorphism (A118G) and naltrexone treatment response in adherent Korean alcohol-dependent patients
-
Kim SG, Kim CM, Choi SW, et al. A mu opioid receptor gene polymorphism (A118G) and naltrexone treatment response in adherent Korean alcohol-dependent patients. Psychopharmacology (Berl) 2009;201:611-18
-
(2009)
Psychopharmacology (Berl)
, vol.201
, pp. 611-18
-
-
Kim, S.G.1
Kim, C.M.2
Choi, S.W.3
-
34
-
-
0037264788
-
Animal models of motivation for drinking in rodents with a focus on opioid receptor neuropharmacology
-
Koob GF, Roberts AJ, Kieffer BL, et al. Animal models of motivation for drinking in rodents with a focus on opioid receptor neuropharmacology. Recent Dev Alcohol 2003;16:263-81
-
(2003)
Recent Dev Alcohol
, vol.16
, pp. 263-81
-
-
Koob, G.F.1
Roberts, A.J.2
Kieffer, B.L.3
-
35
-
-
29044435185
-
Differences in the peripheral levels of beta-endorphin in response to alcohol and stress as a function of alcohol dependence and family history of alcoholism
-
Dai X, Thavundayil J, Gianoulakis C. Differences in the peripheral levels of beta-endorphin in response to alcohol and stress as a function of alcohol dependence and family history of alcoholism. Alcohol Clin Exp Res 2005;29:1965-75
-
(2005)
Alcohol Clin Exp Res
, vol.29
, pp. 1965-75
-
-
Dai, X.1
Thavundayil, J.2
Gianoulakis, C.3
-
36
-
-
27644457033
-
A microdialysis profile of Met-enkephalin release in the rat nucleus accumbens following alcohol administration
-
Marinelli PW, Bai L, Quirion R, Gianoulakis C. A microdialysis profile of Met-enkephalin release in the rat nucleus accumbens following alcohol administration. Alcohol Clin Exp Res 2005;29:1821-8
-
(2005)
Alcohol Clin Exp Res
, vol.29
, pp. 1821-8
-
-
Marinelli, P.W.1
Bai, L.2
Quirion, R.3
Gianoulakis, C.4
-
37
-
-
33744724648
-
A microdialysis profile of dynorphin A1-8 release in the rat nucleus accumbens following alcohol administration
-
Marinelli PW, Lam M, Bai L, et al. A microdialysis profile of dynorphin A1-8 release in the rat nucleus accumbens following alcohol administration. Alcohol Clin Exp Res 2006;30:982-90
-
(2006)
Alcohol Clin Exp Res
, vol.30
, pp. 982-90
-
-
Marinelli, P.W.1
Lam, M.2
Bai, L.3
-
38
-
-
0041874899
-
A microdialysis profile of beta-endorphin and catecholamines in the rat nucleus accumbens following alcohol administration
-
Marinelli PW, Quirion R, Gianoulakis C. A microdialysis profile of beta-endorphin and catecholamines in the rat nucleus accumbens following alcohol administration. Psychopharmacology (Berl) 2003;169:60-7
-
(2003)
Psychopharmacology (Berl)
, vol.169
, pp. 60-7
-
-
Marinelli, P.W.1
Quirion, R.2
Gianoulakis, C.3
-
39
-
-
3342943177
-
An in vivo profile of beta-endorphin release in the arcuate nucleus and nucleus accumbens following exposure to stress or alcohol
-
Marinelli PW, Quirion R, Gianoulakis C. An in vivo profile of beta-endorphin release in the arcuate nucleus and nucleus accumbens following exposure to stress or alcohol. Neuroscience 2004;127:777-84
-
(2004)
Neuroscience
, vol.127
, pp. 777-84
-
-
Marinelli, P.W.1
Quirion, R.2
Gianoulakis, C.3
-
40
-
-
74549132488
-
Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake
-
Barson JR, Carr AJ, Soun JE, et al. Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake. Alcohol Clin Exp Res 2010;34:214-22
-
(2010)
Alcohol Clin Exp Res
, vol.34
, pp. 214-22
-
-
Barson, J.R.1
Carr, A.J.2
Soun, J.E.3
-
41
-
-
0032535299
-
Suppression of ethanol-reinforced behavior by naltrexone is associated with attenuation of the ethanol-induced increase in dialysate dopamine levels in the nucleus accumbens
-
Gonzales RA, Weiss F. Suppression of ethanol-reinforced behavior by naltrexone is associated with attenuation of the ethanol-induced increase in dialysate dopamine levels in the nucleus accumbens. J Neurosci 1998;18:10663-71
-
(1998)
J Neurosci
, vol.18
, pp. 10663-71
-
-
Gonzales, R.A.1
Weiss, F.2
-
42
-
-
0022591828
-
Consumption of ethanol solution is potentiated by morphine and attenuated by naloxone persistently across repeated daily administrations
-
Hubbell CL, Czirr SA, Hunter GA, et al. Consumption of ethanol solution is potentiated by morphine and attenuated by naloxone persistently across repeated daily administrations. Alcohol 1986;3:39-54
-
(1986)
Alcohol
, vol.3
, pp. 39-54
-
-
Hubbell, C.L.1
Czirr, S.A.2
Hunter, G.A.3
-
43
-
-
0024158716
-
Constant infusions of morphine and intakes of sweetened ethanol solution among rats
-
Hubbell CL, Abelson ML, Burkhardt CA, et al. Constant infusions of morphine and intakes of sweetened ethanol solution among rats. Alcohol 1988;5:409-15
-
(1988)
Alcohol
, vol.5
, pp. 409-15
-
-
Hubbell, C.L.1
Abelson, M.L.2
Burkhardt, C.A.3
-
44
-
-
0024156733
-
Ethanol with small doses of morphine establishes a conditioned place preference
-
Marglin SH, MacKechnie DK, Mattie ME, et al. Ethanol with small doses of morphine establishes a conditioned place preference. Alcohol 1988;5:309-13
-
(1988)
Alcohol
, vol.5
, pp. 309-13
-
-
Marglin, S.H.1
MacKechnie, D.K.2
Mattie, M.E.3
-
45
-
-
0030047293
-
Endogenous opioids and alcohol dependence: Opioid alkaloids and the propensity to drink alcoholic beverages
-
Reid LD. Endogenous opioids and alcohol dependence: opioid alkaloids and the propensity to drink alcoholic beverages.Alcohol 1996;13:5-11
-
(1996)
Alcohol
, vol.13
, pp. 5-11
-
-
Reid, L.D.1
-
46
-
-
0017623919
-
Enkephalin may mediate euphoria and drive-reduction reward
-
Belluzzi JD, Stein L. Enkephalin may mediate euphoria and drive-reduction reward. Nature 1977;266:556-8
-
(1977)
Nature
, vol.266
, pp. 556-8
-
-
Belluzzi, J.D.1
Stein, L.2
-
47
-
-
0021240670
-
Self-administration of methionine enkephalin into the nucleus accumbens
-
Goeders NE, Lane JD, Smith JE. Self-administration of methionine enkephalin into the nucleus accumbens. Pharmacol Biochem Behav 1984;20:451-5
-
(1984)
Pharmacol Biochem Behav
, vol.20
, pp. 451-5
-
-
Goeders, N.E.1
Lane, J.D.2
Smith, J.E.3
-
48
-
-
66549117005
-
Effect of acute ethanol administration on the release of opioid peptides from the midbrain including the ventral tegmental area
-
Jarjour S, Bai L, Gianoulakis C. Effect of acute ethanol administration on the release of opioid peptides from the midbrain including the ventral tegmental area. Alcohol Clin Exp Res 2009;33:1033-43
-
(2009)
Alcohol Clin Exp Res
, vol.33
, pp. 1033-43
-
-
Jarjour, S.1
Bai, L.2
Gianoulakis, C.3
-
49
-
-
3042515206
-
Pharmacotherapy ofalcohol dependence: A review of the clinical data
-
Mann K. Pharmacotherapy ofalcohol dependence: a review of the clinical data. CNS Drugs 2004;18:485-504
-
(2004)
CNS Drugs
, vol.18
, pp. 485-504
-
-
Mann, K.1
-
50
-
-
33646140109
-
Reward-motivated learning: Mesolimbic activation precedes memory formation
-
Adcock RA, Thangavel A, Whitfield-Gabrieli S, et al. Reward-motivated learning: mesolimbic activation precedes memory formation. Neuron 2006;50:507-17
-
(2006)
Neuron
, vol.50
, pp. 507-17
-
-
Adcock, R.A.1
Thangavel, A.2
Whitfield-Gabrieli, S.3
-
51
-
-
0037264509
-
Advances in the use of naltrexone: An integration of preclinical and clinical findings
-
O'Malley SS, Froehlich JC. Advances in the use of naltrexone: an integration of preclinical and clinical findings. Recent Dev Alcohol 2003;16:217-45
-
(2003)
Recent Dev Alcohol
, vol.16
, pp. 217-45
-
-
O'Malley, S.S.1
Froehlich, J.C.2
-
52
-
-
77953217327
-
Ethanol-induced activation of AKT and DARPP-32 in the mouse striatum mediated by opioid receptors
-
Bjork K, Terasmaa A, Sun H, et al. Ethanol-induced activation of AKT and DARPP-32 in the mouse striatum mediated by opioid receptors. Addict Biol 2010;15:299-303
-
(2010)
Addict Biol
, vol.15
, pp. 299-303
-
-
Bjork, K.1
Terasmaa, A.2
Sun, H.3
-
53
-
-
67649985942
-
Alcoholism: A systems approach from molecular physiology to addictive behavior
-
Spanagel R Alcoholism: a systems approach from molecular physiology to addictive behavior. Physiol Rev 2009;89:649-705
-
(2009)
Physiol Rev
, vol.89
, pp. 649-705
-
-
Spanagel, R.1
-
55
-
-
0034537207
-
Repeated ethanol administration induces short-and long-term changes in enkephalin and dynorphin tissue concentrations in rat brain
-
Lindholm S, Ploj K, FranckJ, Nylander I. Repeated ethanol administration induces short-and long-term changes in enkephalin and dynorphin tissue concentrations in rat brain. Alcohol 2000;22:165-71
-
(2000)
Alcohol
, vol.22
, pp. 165-71
-
-
Lindholm, S.1
Ploj, K.2
Franckj Nylander, I.3
-
56
-
-
0034028920
-
Effect of chronic ethanol and withdrawal on the μ-opioid receptor-and 5-hydroxytryptamine1A receptor-stimulated binding of [35S]guanosine-5 '-O-(3-thio)triphosphate in the fawn-hooded rat brain: A quantitative autoradiography study
-
Chen F, Lawrence AJ. Effect of chronic ethanol and withdrawal on the μ-opioid receptor-and 5-hydroxytryptamine1A receptor-stimulated binding of [35S]guanosine-5 '-O-(3-thio)triphosphate in the fawn-hooded rat brain: a quantitative autoradiography study. J Pharmacol Exp Ther 2000;293:159-65
-
(2000)
J Pharmacol Exp Ther
, vol.293
, pp. 159-65
-
-
Chen, F.1
Lawrence, A.J.2
-
57
-
-
0032913423
-
The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat
-
Turchan J, Przewlocka B, Toth G, et al. The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat. Neuroscience 1999;91:971-7
-
(1999)
Neuroscience
, vol.91
, pp. 971-7
-
-
Turchan, J.1
Przewlocka, B.2
Toth, G.3
-
58
-
-
0034863007
-
Alterations in central preproenkephalin mRNA expression after chronic free-choice ethanol consumption by fawn-hooded rats
-
Cowen MS, Lawrence AJ. Alterations in central preproenkephalin mRNA expression after chronic free-choice ethanol consumption by fawn-hooded rats. Alcohol Clin Exp Res 2001;25:1126-33
-
(2001)
Alcohol Clin Exp Res
, vol.25
, pp. 1126-33
-
-
Cowen, M.S.1
Lawrence, A.J.2
-
59
-
-
19244369081
-
Przewlocki R Ethanol withdrawal enhances the prodynorphin system activity in the rat nucleus accumbens
-
Przewlocka B, Turchan J, Lason W, Przewlocki R Ethanol withdrawal enhances the prodynorphin system activity in the rat nucleus accumbens. Neurosci Lett 1997;238:13-6
-
(1997)
Neurosci Lett
, vol.238
, pp. 13-6
-
-
Przewlocka, B.1
Turchan, J.2
Lason, W.3
-
60
-
-
0032870007
-
Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens
-
Rosin A, Lindholm S, Franck J, Georgieva J. Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens. Neurosci Lett 1999;275:1-4
-
(1999)
Neurosci Lett
, vol.275
, pp. 1-4
-
-
Rosin, A.1
Lindholm, S.2
Franck, J.3
Georgieva, J.4
-
61
-
-
1642482761
-
Mu-opioid receptor binding measured by [11C]carfentanil positron emission tomography is related to craving and mood in alcohol dependence
-
Bencherif B, Wand GS, McCaul ME, et al. Mu-opioid receptor binding measured by [11C]carfentanil positron emission tomography is related to craving and mood in alcohol dependence. Biol Psychiatry 2004;55:255-62
-
(2004)
Biol Psychiatry
, vol.55
, pp. 255-62
-
-
Bencherif, B.1
Wand, G.S.2
McCaul, M.E.3
-
62
-
-
19944426685
-
Correlation of stable elevations in striatal μ-opioid receptor availability in detoxified alcoholic patients with alcohol craving: A positron emission tomography study using carbon 11-labeled carfentanil
-
Heinz A, Reimold M, Wrase J, et al. Correlation of stable elevations in striatal μ-opioid receptor availability in detoxified alcoholic patients with alcohol craving: a positron emission tomography study using carbon 11-labeled carfentanil. Arch Gen Psychiatry 2005;62:57-64
-
(2005)
Arch Gen Psychiatry
, vol.62
, pp. 57-64
-
-
Heinz, A.1
Reimold, M.2
Wrase, J.3
-
64
-
-
0030041684
-
Naltrexone in the treatment of alcoholism: A clinical review
-
O'Brien CP, Volpicelli LA, Volpicelli JR. Naltrexone in the treatment of alcoholism: a clinical review. Alcohol 1996;13:35-9
-
(1996)
Alcohol
, vol.13
, pp. 35-9
-
-
O'Brien, C.P.1
Volpicelli, L.A.2
Volpicelli, J.R.3
-
65
-
-
0034057478
-
Naltrexone vs. nefazodone for treatment of alcohol dependence. A placebo-controlled trial
-
Kranzler HR, Modesto-Lowe V, Van Kirk J. Naltrexone vs. nefazodone for treatment of alcohol dependence. A placebo-controlled trial. Neuropsychopharmacology 2000;22:493-503
-
(2000)
Neuropsychopharmacology
, vol.22
, pp. 493-503
-
-
Kranzler, H.R.1
Modesto-Lowe, V.2
Van Kirk, J.3
-
66
-
-
0033972388
-
Naltrexone-induced nausea in patients treated for alcohol dependence: Clinical predictors and evidence for opioid-mediated effects
-
O'Malley SS, Krishnan-Sarin S, Farren C, OConnor PG. Naltrexone-induced nausea in patients treated for alcohol dependence: clinical predictors and evidence for opioid-mediated effects. J Clin Psychopharmacol 2000;20:69-76
-
(2000)
J Clin Psychopharmacol
, vol.20
, pp. 69-76
-
-
O'Malley, S.S.1
Krishnan-Sarin, S.2
Farren, C.3
Oconnor, P.G.4
-
67
-
-
0035093487
-
Adverse effects of oral naltrexone: Analysis of data from two clinical trials
-
Oncken C, Van Kirk J, Kranzler HR. Adverse effects of oral naltrexone: analysis of data from two clinical trials. Psychopharmacology (Berl) 2001;154:397-402
-
(2001)
Psychopharmacology (Berl)
, vol.154
, pp. 397-402
-
-
Oncken, C.1
Van Kirk, J.2
Kranzler, H.R.3
-
68
-
-
0032765495
-
A double-blind, placebo-controlled study of oral nalmefene for alcohol dependence
-
Mason BJ, Salvato FR, Williams LD, et al. A double-blind, placebo-controlled study of oral nalmefene for alcohol dependence. Arch Gen Psychiatry 1999;56:719-24
-
(1999)
Arch Gen Psychiatry
, vol.56
, pp. 719-24
-
-
Mason, B.J.1
Salvato, F.R.2
Williams, L.D.3
-
69
-
-
0028109622
-
Binding affinity and selectivity of opioids at mu, delta and kappa receptors in monkey brain membranes
-
Emmerson PJ, Liu MR, Woods JH, Medzihradsky F. Binding affinity and selectivity of opioids at mu, delta and kappa receptors in monkey brain membranes. J Pharmacol Exp Ther 1994;271:1630-7
-
(1994)
J Pharmacol Exp Ther
, vol.271
, pp. 1630-7
-
-
Emmerson, P.J.1
Liu, M.R.2
Woods, J.H.3
Medzihradsky, F.4
-
70
-
-
27844515196
-
Prolonged central mu-opioid receptor occupancy after single and repeated nalmefene dosing
-
Ingman K, Hagelberg N, Aalto S, et al. Prolonged central mu-opioid receptor occupancy after single and repeated nalmefene dosing. Neuropsychopharmacology 2005;30:2245-53
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 2245-53
-
-
Ingman, K.1
Hagelberg, N.2
Aalto, S.3
-
71
-
-
0023551360
-
Nalmefene: Safety and kinetics after single and multiple oral doses of a new opioid antagonist
-
Dixon R, Gentile J, Hsu HB, et al. Nalmefene: safety and kinetics after single and multiple oral doses of a new opioid antagonist. J Clin Pharmacol 1987;27:233-9
-
(1987)
J Clin Pharmacol
, vol.27
, pp. 233-9
-
-
Dixon, R.1
Gentile, J.2
Hsu, H.B.3
-
72
-
-
0023003262
-
Dixon R Prolonged blockade of opioid effect with oral nalmefene
-
Gal TJ, DiFazio CA, Dixon R Prolonged blockade of opioid effect with oral nalmefene. Clin Pharmacol Ther 1986;40:537-42
-
(1986)
Clin Pharmacol Ther
, vol.40
, pp. 537-42
-
-
Gal, T.J.1
Difazio, C.A.2
-
73
-
-
0025642635
-
Pharmacologic profile of NPC 168 (naltrexone phenyl oxime), a novel compound with activity at opioid receptors
-
DeHaven-Hudkins DL, Brostrom PA, Allen JT, et al. Pharmacologic profile of NPC 168 (naltrexone phenyl oxime), a novel compound with activity at opioid receptors. Pharmacol Biochem Behav 1990;37:497-504
-
(1990)
Pharmacol Biochem Behav
, vol.37
, pp. 497-504
-
-
Dehaven-Hudkins, D.L.1
Brostrom, P.A.2
Allen, J.T.3
-
75
-
-
0022253984
-
Binding of a new opiate antagonist, nalmefene, to rat brain membranes
-
Michel ME, Bolger G, Weissman BA. Binding of a new opiate antagonist, nalmefene, to rat brain membranes. Methods Find Exp Clin Pharmacol 1985;7:175-7
-
(1985)
Methods Find Exp Clin Pharmacol
, vol.7
, pp. 175-7
-
-
Michel, M.E.1
Bolger, G.2
Weissman, B.A.3
-
76
-
-
38149072294
-
Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence
-
Walker BM, Koob GF. Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. Neuropsychopharmacology 2008;33:643-52
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 643-52
-
-
Walker, B.M.1
Koob, G.F.2
-
77
-
-
77950689016
-
In vivo characterization of the opioid antagonist nalmefene in mice
-
Osborn MD, Lowery JJ, Skorput AG, et al. In vivo characterization of the opioid antagonist nalmefene in mice. Life Sci 2010;86:624-30
-
(2010)
Life Sci
, vol.86
, pp. 624-30
-
-
Osborn, M.D.1
Lowery, J.J.2
Skorput, A.G.3
-
78
-
-
0030659004
-
Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system
-
Kim S, Wagner HN Jr, Villemagne VL, et al. Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system. J Nucl Med 1997;38:1726-31
-
(1997)
J Nucl Med
, vol.38
, pp. 1726-31
-
-
Kim, S.1
Wagner Jr., H.N.2
Villemagne, V.L.3
-
79
-
-
29144520710
-
Pharmacogenetics of opioid receptors and addiction
-
Mayer P, Hollt V. Pharmacogenetics of opioid receptors and addiction. Pharmacogenet Genomics 2006;16:1-7
-
(2006)
Pharmacogenet Genomics
, vol.16
, pp. 1-7
-
-
Mayer, P.1
Hollt, V.2
-
80
-
-
0027943602
-
A double-blind, placebo-controlled pilot study to evaluate the efficacy and safety of oral nalmefene HCl for alcohol dependence
-
Mason BJ, Ritvo EC, Morgan RO, et al. A double-blind, placebo-controlled pilot study to evaluate the efficacy and safety of oral nalmefene HCl for alcohol dependence. Alcohol Clin Exp Res 1994;18:1162-7
-
(1994)
Alcohol Clin Exp Res
, vol.18
, pp. 1162-7
-
-
Mason, B.J.1
Ritvo, E.C.2
Morgan, R.O.3
-
81
-
-
3242660877
-
A multi-site dose ranging study of nalmefene in the treatment of alcohol dependence
-
Anton RF, Pettinati H, Zweben A, et al. A multi-site dose ranging study of nalmefene in the treatment of alcohol dependence. J Clin Psychopharmacol 2004;24:421-8
-
(2004)
J Clin Psychopharmacol
, vol.24
, pp. 421-8
-
-
Anton, R.F.1
Pettinati, H.2
Zweben, A.3
-
82
-
-
0032407588
-
The opioid receptor antagonist nalmefene reduces responding maintained by ethanol presentation: Preclinical studies in ethanol-preferring and outbred Wistar rats
-
June HL, Grey C, Warren-Reese C, et al. The opioid receptor antagonist nalmefene reduces responding maintained by ethanol presentation: preclinical studies in ethanol-preferring and outbred Wistar rats. Alcohol Clin Exp Res 1998;22:2174-85
-
(1998)
Alcohol Clin Exp Res
, vol.22
, pp. 2174-85
-
-
June, H.L.1
Grey, C.2
Warren-Reese, C.3
-
83
-
-
4544346571
-
Effects of naltrexone and nalmefene on subjective response to alcohol among non-treatment-seeking alcoholics and social drinkers
-
Drobes DJ, Anton RF, Thomas SE, Voronin K. Effects of naltrexone and nalmefene on subjective response to alcohol among non-treatment-seeking alcoholics and social drinkers. Alcohol Clin Exp Res 2004;28:1362-70
-
(2004)
Alcohol Clin Exp Res
, vol.28
, pp. 1362-70
-
-
Drobes, D.J.1
Anton, R.F.2
Thomas, S.E.3
Voronin, K.4
-
84
-
-
0037712812
-
A clinical laboratory paradigm for evaluating medication effects on alcohol consumption: Naltrexone and nalmefene
-
Drobes DJ, Anton RF, Thomas SE, Voronin K. A clinical laboratory paradigm for evaluating medication effects on alcohol consumption: naltrexone and nalmefene. Neuropsychopharmacology 2003;28:755-64
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 755-64
-
-
Drobes, D.J.1
Anton, R.F.2
Thomas, S.E.3
Voronin, K.4
-
85
-
-
34250616600
-
Targeted nalmefene with simple medical management in the treatment of heavy drinkers: A randomized double-blind placebo-controlled multicenter study
-
Karhuvaara S, Simojoki K, Virta A, et al. Targeted nalmefene with simple medical management in the treatment of heavy drinkers: a randomized double-blind placebo-controlled multicenter study. Alcohol Clin Exp Res 2007;31:1179-87
-
(2007)
Alcohol Clin Exp Res
, vol.31
, pp. 1179-87
-
-
Karhuvaara, S.1
Simojoki, K.2
Virta, A.3
-
86
-
-
54749152894
-
Effects of opioid receptor gene variation on targeted nalmefene treatment in heavy drinkers
-
Arias AJ, Armeli S, Gelernter J, et al. Effects of opioid receptor gene variation on targeted nalmefene treatment in heavy drinkers. Alcohol Clin Exp Res 2008;32:1159-66
-
(2008)
Alcohol Clin Exp Res
, vol.32
, pp. 1159-66
-
-
Arias, A.J.1
Armeli, S.2
Gelernter, J.3
-
87
-
-
33645007938
-
Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling
-
Grant JE, Potenza MN, Hollander E, et al. Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling. Am J Psychiatry 2006;163:303-12
-
(2006)
Am J Psychiatry
, vol.163
, pp. 303-12
-
-
Grant, J.E.1
Potenza, M.N.2
Hollander, E.3
-
88
-
-
21644437224
-
Does effect size in naltrexone trials for alcohol dependence differ for single-site vs. multi-center studies?
-
Feinn R, Kranzler HR. Does effect size in naltrexone trials for alcohol dependence differ for single-site vs. multi-center studies? Alcohol Clin Exp Res 2005;29:983-8
-
(2005)
Alcohol Clin Exp Res
, vol.29
, pp. 983-8
-
-
Feinn, R.1
Kranzler, H.R.2
|