Physiological concentrations of serum cortisol are related to vascular risk markers in prepubertal children

Pediatric Research

Volumn 68, Issue 5, 2010, Pages 452-455

  Soriano Rodríguez, Pilar ^a   Osiniri, Inés ^a   Grau Cabrera, Pilar ^a   Riera Pérez, Elena ^a   Prats Puig, Anna ^b,c   Carbonell Alferez, Míriam ^a   Schneider, Stephan ^a   Mora Maruny, Carme ^a   De Zegher, Francis ^d   Ibánez, Lourdes ^e   Bassols, Judit ^b,c   López Bermejo, Abel ^b,c  

^a Salut Emporda Foundation   (Spain)

^b HOSPITAL JOSEP TRUETA   (Spain)

^c GIRONA BIOMEDICAL RESEARCH INSTITUTE IDIBGI   (Spain)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROCORTISONE; TRIACYLGLYCEROL;

ARTERIAL WALL THICKNESS; ARTICLE; BODY FAT; BODY MASS; CARDIOVASCULAR RISK; CHILD; CLINICAL ASSESSMENT; DIASTOLIC BLOOD PRESSURE; FEMALE; GLUCOSE BLOOD LEVEL; HEART RATE; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; INSULIN RESISTANCE; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NORMAL HUMAN; PHYSIOLOGICAL PROCESS; PREPUBERTY; PRESCHOOL CHILD; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; SCHOOL CHILD; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE;

ADULT; BIOLOGICAL MARKERS; CARDIOVASCULAR DISEASES; CHILD; FEMALE; HUMANS; HYDROCORTISONE; MALE; RISK FACTORS;

EID: 77958472065     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/PDR.0b013e3181efc310     Document Type: Article

References (36)

1. Ward AM, Fall CH, Stein CE, Kumaran K, Veena SR, Wood PJ, Syddall HE, Phillips DI 2003 Cortisol and the metabolic syndrome in South Asians. Clin Endocrinol (Oxf) 58:500-505
2. Kelly JJ, Tam SH, Williamson PM, Lawson J, Whitworth JA 1998 The nitric oxide system and cortisol-induced hypertension in humans. Clin Exp Pharmacol Physiol 25:945-946
3. Phillips DI, Barker DJ, Fall CH, Seckl JR, Whorwood CB, Wood PJ, Walker BR 1998 Elevated plasma cortisol concentrations: a link between low birth weight and the insulin resistance syndrome? J Clin Endocrinol Metab 83:757-760
4. Weigensberg MJ, Toledo-Corral CM, Goran MI 2008 Association between the metabolic syndrome and serum cortisol in overweight Latino youth. J Clin Endo-crinol Metab 93:1372-1378
5. Honour JW, Jones R, Leary S, Golding J, Ong KK, Dunger DB 2007 Relationships of urinary adrenal steroids at age 8 years with birth weight, postnatal growth, blood pressure, and glucose metabolism. J Clin Endocrinol Metab 92:4340-4345
6. Walker BR, Yau JL, Brett LP, Seckl JR, Monder C, Williams BC, Edwards CR 1991 11 beta-hydroxysteroid dehydrogenase in vascular smooth muscle and heart: implications for cardiovascular responses to glucocorticoids. Endocrinology 129:3305-3312
7. Soro A, Ingram MC, Tonolo G, Glorioso N, Fraser R 1995 Evidence of coexisting changes in 11 beta-hydroxysteroid dehydrogenase and 5 beta-reductase activity in subjects with untreated essential hypertension. Hypertension 25:67-70
8. Litchfield WR, Hunt SC, Jeunemaitre X, Fisher ND, Hopkins PN, Williams RR, Corvol P, Williams GH 1998 Increased urinary free cortisol: a potential intermediate phenotype of essential hypertension. Hypertension 31:569-574
9. Ong SL, Zhang Y, Whitworth JA 2008 Reactive oxygen species and glucocorticoid-induced hypertension. Clin Exp Pharmacol Physiol 35:477-482
10. Alevizaki M, Cimponeriu A, Lekakis J, Papamichael C, Chrousos GP 2007 High anticipatory stress plasma cortisol levels and sensitivity to glucocorticoids predict severity of coronary artery disease in subjects undergoing coronary angiography. Metabolism 56:222-226
11. Dekker MJ, Koper JW, van Aken MO, Pols HA, Hofman A, de Jong FH, Kirsch-baum C, Witteman JC, Lamberts SW, Tiemeier H 2008 Salivary cortisol is related to atherosclerosis of carotid arteries. J Clin Endocrinol Metab 93:3741-3747
12. Smith GD, Ben-Shlomo Y, Beswick A, Yarnell J, Lightman S, Elwood P 2005 Cortisol, testosterone, and coronary heart disease: prospective evidence from the Caerphilly study. Circulation 112:332-340
13. Eller NH, Netterstrom B, Allerup P 2005 Progression in intima media thickness\-the significance of hormonal biomarkers of chronic stress. Psychoneuroendocrinology 30:715-723
14. Peppa-Patrikiou M, Scordili M, Antoniou A, Giannaki M, Dracopoulou M, Dacou-Voutetakis C 1998 Carotid atherosclerosis in adolescents and young adults with IDDM. Relation to urinary endothelin, albumin, free cortisol, and other factors. Diabetes Care 21:1004-1007 (Pubitemid 28488796)
15. Berenson GS 2002 Childhood risk factors predict adult risk associated with subclin-ical cardiovascular disease. The Bogalusa Heart Study. Am J Cardiol 90:3L-7L
16. Cortés-Blanco A, Ferrández Longás A, Mayayo Dehesa E, Labarta Aizpún JI, Martínez-Lázaro R 2000 [Hormonal reference values for adrenocortical function in healthy children from Zaragoza]. An Esp Pediatr 52:106-115
17. Therrien F, Drapeau V, Lalonde J, Lupien SJ, Beaulieu S, Tremblay A, Richard D 2007 Awakening cortisol response in lean, obese, and reduced obese individuals: effect of gender and fat distribution. Obesity (Silver Spring) 15:377-385
18. Barat P, Gayard-Cros M, Andrew R, Corcuff JB, Jouret B, Barthe N, Perez P, Germain C, Tauber M, Walker BR, Mormede P, Duclos M 2007 Truncal distribution of fat mass, metabolic profile and hypothalamic-pituitary adrenal axis activity in prepubertal obese children. J Pediatr 150:535-539, 539.e1
19. Misra M, Bredella MA, Tsai P, Mendes N, Miller KK, Klibanski A 2008 Lower growth hormone and higher cortisol are associated with greater visceral adiposity, intramyocellular lipids, and insulin resistance in overweight girls. Am J Physiol Endocrinol Metab 295:E385-E392
20. Purnell JQ, Kahn SE, Samuels MH, Brandon D, Loriaux DL, Brunzell JD 2009 Enhanced cortisol production rates, free cortisol, and 11beta-HSD-1 expression correlate with visceral fat and insulin resistance in men: effect of weight loss. Am J Physiol Endocrinol Metab 296:E351-E357
21. Reinehr T, Andler W 2004 Cortisol and its relation to insulin resistance before and after weight loss in obese children. Horm Res 62:107-112 (Pubitemid 39274243)
22. Walker BR, Soderberg S, Lindahl B, Olsson T 2000 Independent effects of obesity and cortisol in predicting cardiovascular risk factors in men and women. J Intern Med 247:198-204
23. Purnell JQ, Brandon DD, Isabelle LM, Loriaux DL, Samuels MH 2004 Association of 24-hour cortisol production rates, cortisol-binding globulin, and plasma-free cortisol levels with body composition, leptin levels, and aging in adult men and women. J Clin Endocrinol Metab 89:281-287
24. Filipovsky J, Ducimetiere P, Eschwege E, Richard JL, Rosselin G, Claude JR 1996 The relationship of blood pressure with glucose, insulin, heart rate, free fatty acids and plasma cortisol levels according to degree of obesity in middle-aged men. J Hypertens 14:229-235
25. Rosmond R, Dallman MF, Bjorntorp P 1998 Stress-related cortisol secretion in men: relationships with abdominal obesity and endocrine, metabolic and hemodynamic abnormalities. J Clin Endocrinol Metab 83:1853-1859
26. Huh SY, Andrew R, Rich-Edwards JW, Kleinman KP, Seckl JR, Gillman MW 2008 Association between umbilical cord glucocorticoids and blood pressure at age 3 years. BMC Med 6:25
27. Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE 1997 Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation 96:1432-1437
28. Pauciullo P, Iannuzzi A, Sartorio R, Irace C, Covetti G, Di Costanzo A, Rubba P 1994 Increased intima-media thickness of the common carotid artery in hypercho-lesterolemic children. Arterioscler Thromb 14:1075-1079
29. Wudy SA, Hartmann MF, Remer T 2007 Sexual dimorphism in cortisol secretion starts after age 10 in healthy children: urinary cortisol metabolite excretion rates during growth. Am J Physiol Endocrinol Metab 293:E970-E976
30. Jones A, Beda A, Osmond C, Godfrey KM, Simpson DM, Phillips DI 2008 Sex-specific programming of cardiovascular physiology in children. Eur Heart J 29:2164-2170
31. Walker BR 2007 Glucocorticoids and cardiovascular disease. Eur J Endocrinol 157:545-559
32. Bjorntorp P, Holm G, Rosmond R 1999 Hypothalamic arousal, insulin resistance and type 2 diabetes mellitus. Diabet Med 16:373-383
33. Mangos GJ, Walker BR, Kelly JJ, Lawson JA, Webb DJ, Whitworth JA 2000 Cortisol inhibits cholinergic vasodilation in the human forearm. Am J Hypertens 13:1155-1160
34. Hadoke PW, Macdonald L, Logie JJ, Small GR, Dover AR, Walker BR 2006 Intra-vascular glucocorticoid metabolism as a modulator of vascular structure and function. Cell Mol Life Sci 63:565-578
35. Ullian ME 1999 The role of corticosteriods in the regulation of vascular tone. Cardiovasc Res 41:55-64
36. Pruessner JC, Wolf OT, Hellhammer DH, Buske-Kirschbaum A, von Auer K, Jobst S, Kaspers F, Kirschbaum C 1997 Free cortisol levels after awakening: a reliable biological marker for the assessment of adrenocortical activity. Life Sci 61:2539-2549