Synthesis and In Vivo acute anti hyperglycemic evaluation of novel isosteviol derivatives

Letters in Drug Design and Discovery

Volumn 7, Issue 9, 2010, Pages 686-693

  Chen, Junqing ^a   Zha, Xiaoming ^b   Sun, Min ^a   Cai, Jin ^a   Zhou, Wen ^a   Ji, Min ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Acute antihyperglycemeric; Derivatives; Isosteviol; Synthesis

Indexed keywords

(4ALPHA,8BETA) 13 METHYL 16 HYDROXYIMINO 17 NORKAURAN 18 OIC ISOPROPYLESTER; (4ALPHA,8BETA) 13BETA METHYL 13ALPHA AMINO 16 CARBOXYL 13,16 LACTAMYL 17 NORKAURAN 18 OIC ISOPROPYLESTER; (4ALPHA,8BETA) 13BETA METHYL 13ALPHA AMINO 16 CARBOXYL 13,16 LACTAMYL 17 NORKAURAN 18 OL; (4ALPHA,8BETA) 13BETA METHYL 13ALPHA AMINO 16 HYDROXY 13,16 LACTAMYL 17 NORKAURAN 18 OIC; (4ALPHA,8BETA,13BETA) 13 METHY 16 OXO 17 NORKAURAN 18 N BUTYLESTER; (4ALPHA,8BETA,13BETA) 13 METHY 16 OXO 17 NORKAURAN 18 N ISOPROPYLESTER; (4ALPHA,8BETA,13BETA) 13 METHY 16 OXO 17 NORKAURAN 18 OIC ACETOXYLMETHYLESTER; (4ALPHA,8BETA,13BETA) 13 METHY 16 OXO 17 NORKAURAN 18 OIC SODIUM; (4ALPHA,8BETA,13BETA) 13 METHY 16 OXO 17 NORKAURAN 18 OL; (4ALPHA,8BETA,13BETA) 13 METHYL 16 HYDROXYIMINO 17 NORKAURAN 18 OIC ISOPROPYLESTER; (4ALPHA,8BETA,13BETA) 13 METHYL 16 OXO 17 NORKAURAN 18 OIC 2',3' DIHYDROXYPROPYLESTER; (4ALPHA,8BETA,13BETA) 13 METHYL 16 OXO 17 NORKAURAN 18 OIC 4' BROMO BUTYLESTER; (4ALPHA,8BETA,13BETA) 13 METHYL 16 OXO 17 NORKAURAN 18 OIC 4' NICOTINYLBUTYLESTER; (4ALPHA,8BETA,13BETA) 13 METHYL 16 OXO 17 NORKAURAN 18 OIC 4' NITRO N BUTYLESTER; (4ALPHA,8BETA,13BETA) 13 METHYL 16 OXO 17 NORKAURAN 18 OIC 4' NITROBENZOYLOXYMETHYLESTER; (4ALPHA,8BETA,13BETA) 13 METHYL 16 OXO 17 NORKAURAN 18 OIC ACID; (4ALPHA,8BETA,13BETA) 13 METHYL 16,16 -ETHYLENEDIOXY 17 NORKAURAN 18 OIC ISOPROPYLESTER; (4ALPHA,8BETA,13BETA) 16 NICOTINYL 13 METHYL 16 OXO 17 NORKAURAN 18 OIC ACID; (4ALPHA,8BETA,13BETA,16ALPHA) 13 METHYL 16 HYDROXYL 17 NORKAURAN 18 OIC ACID ISOPROPYLESTER; (4ALPHA,8BETA,13BETA,16ALPHA) 13 METHYL 16 HYDROXYL 17 NORKAURAN 18 OIC ISOPROPYLESTER; 2,2 DIMETHYL 1,3 DIOXOLAN 4 METHANOL; CARBONYL DERIVATIVE; CARBOXYL GROUP; CHLOROMETHYL 4 NITROBENZOATE; DI [(4ALPHA,8BETA,13BETA) 13 METHY 16 OXO 17 NORKAURAN 18 OIC]METHYLENE ESTER; HYPERGLYCEMIC AGENT; ISOSTEVIOL DERIVATIVE; ROSIGLITAZONE; STEVIOL; STEVIOSIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GLUCOSE BLOOD LEVEL; IN VIVO STUDY; IRRADIATION; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ACTIVITY RELATION;

EID: 77958456233     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018010792929522     Document Type: Article

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