Activity of isosteviol lactone on mitochondrial metabolism

Toxicology Letters

Volumn 143, Issue 1, 2003, Pages 83-92

  Braguini, Welligton L ^a   Gomes, Maria A Biazon ^a   De Oliveira, Brás H ^a   Carnieri, Eva G S ^a   Rocha, Maria Eliane M ^a   De Oliveira, Maria Benigna M ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

Cyclic voltammetry; Diterpenoids; Enzymes; Isosteviol; Isosteviol lactone; Mitochondria; Respiratory chain; Swelling

Indexed keywords

ADENOSINE DIPHOSPHATE; CYTOCHROME C OXIDASE; GLUTAMATE DEHYDROGENASE; ISOSTEVIOL LACTONE; LACTONE DERIVATIVE; POTASSIUM NITRATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG; VALINOMYCIN;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL REACTION; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYCLIC POTENTIOMETRY; ENZYME INHIBITION; LACTONIZATION; LIVER; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MITOCHONDRION SWELLING; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; RESPIRATION CONTROL; RESPIRATORY CHAIN; TOXICITY;

EID: 0347092238     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(03)00074-2     Document Type: Article

References (42)

1. Avent A.G., Hanson J.R., Oliveira B.H. Hydrolysis of the diterpenoid glycoside, stevioside. Phytochemistry. 29:1990;2712-2715.
2. Bridel M., Lavieille R. Le principe à saveur sucrée du kaá-hê-é (Stevia rebaudiana Bertoni). Bull. Soc. Chim. Biol. 13:1931;636-655.
3. Blumenthal M., Goldberg A., Brinckmann J. Herbal Medicine: Expanded Commission and Monographs. 2000;Integrative Medicine Communications, Boston.
4. Chance B., Williams G.R. The respiratory enzymes in oxidative phosphorylation: kinetics of oxygen utilization. J. Biol. Chem. 217:1955;383-393.
5. Chen K., Shi Q., Kashiwada Y., Zhang D.C., Hu C.Q., Jin J.Q., Nozaki H., Kilkuskie R.E., Tramontano E., Cheng Y.C. Salaspermic acid, an anti-HIV principle from Tripterygium wilfordii, and the structure-activity correlation with its related compounds. J. Nat. Prod. 55:1992;340-346.
6. Dewick P.M. Medicinal Natural Products. 1997;Wiley, West Sussex, UK.
7. Estabrook R.W. Mitochondrial respiratory control and the polarography measurement of ADP/O ratios. Methods Enzymol. 10:1967;41-47.
8. Ferreira F.M.L., Madeira V.M.C., Moreno A.J. Interactions of 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene with mitochondrial oxidative phosphorylation. Biochem. Pharmacol. 53:1997;299-308.
9. Fujita E., Node M. Diterpenoids of Rhabdosia species. Org. Nat. Prod. 46:1984;145-149.
10. Ghisalberti E.L. The biological activity of naturally occurring kaurene diterpenes. Fitoterapia - The Biological. 23:1997;303-325.
11. Heldt H.W. Isoprenoids. Plant Biochemistry and Molecular Biology. 1997;360-376 Oxford University Press, Oxford.
12. Hodnick W.F., Milosavljevic E.B., Nelson J.H., Pardini R.S. Relationships between redox potentials, inhibition of mitochondrial respiration, and production of oxygen radicals by flavonoids. Biochem. Pharmacol. 37:1988;2607-2611.
13. Kelmer-Bracht A., Alvarez M., Bracht A. Effects of Stevia rebaudiana natural products on rat liver mitochondria. Biochem. Pharmacol. 34:1985;873-882.
14. Kubota T., Kubo L. The two bitter principles of Isodon shikokianus Kudo. Short Commun. 42:1969;1778.
15. Liu J.C., Kao P.F., Hsieh M.H., Chen Y.J., Chan P. The antihypertensive effect of stevioside derivative isosteviol in spontaneously hypertensive rats. Acta Cardiol. Sin. 17:2001;133-140.
16. Lowry O.H., Rosebrough N.J., Farr A.C., Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
17. Mason T.L., Poyton R.O., Wharton D.C., Schatz G. Cytochrome c oxidase from bakers yeast. I - Isolation and properties. J. Biol. Chem. 248:1973;1346-1354.
18. Melis M.S. Effects of chronic administration of Stevia rebaudiana on fertility in rats. J. Ethnopharmacol. 167:1999;157-161.
19. Melis M.S., Sainati A.R. Influence of calcium on the blood pressure and renal effects of stevioside. Braz. J. Med. Biol. Res. 25:1992;943-949.
20. Melis M.S., Macial R.E., Sainati A.R. Effect of indomethacin on the action of stevioside on mean arterial pressure and on renal function in rats. IRCS Med. Sci. 13:1985;1230-1231.
21. Moreno A.J.M., Madeira V.M.C. Interference of parathion with mitochondrial bioenergetics. Biochim. Biophys. Acta. 1015:1990;361-367.
22. Nanayakara N.P.D., Klocke J.A., Compadre C.M., Hussain R.A., Pezzuto J.M., Kinghorn A.D. Characterization and feeding deterrent effects on the aphid, Schizaphis graminum, of some derivatives of the sweet compounds, stevioside and rebaudioside. J. Nat. Prod. 50:1987;434-441.
23. + exchange in rat liver mitochondria. J. Biol. Chem. 287:1982;9252-9254.
24. Nicholls D.G., Ferguson S.J. Bioenergetics 2. 1992;29-30 Academic Press, London.
25. Node M., Sai M., Fuji K., Fujita E., Takeda S., Uhemi N. Antitumor activity of diterpenoids, trichoraboals a, b and c, and the related compounds: synergism of two sites. Chem. Pharm. Bull. 31:1983;1433-1437.
26. Oliveira B.H., Hanson J.R. Stevioside and related sweet diterpenoid glycosides. J. Nat. Prod. 10:1993;301.
27. Phillipson J.D. Natural products as drugs. Trans. R. Soc. Trop. Med. Hyg. 88:1994;17-19.
28. Picman A.K. Biological activities of sequiterpenes lactones. Biochem. Syst. Ecol. 14:1986;255-281.
29. Planas G.M., Kué J. Contraceptive properties of Stevia rebaudiana. Science. 162:1968;1007.
30. Pressman B.C. Biological applications of ionophores. Ann. Rev. Biochem. 45:1976;501-530.
31. Rodríguez-Linde M.E., Díaz R.M., Garcia-Granados J., Quevedo-Sarmiento E.M., Onorato M.R., Parra A., Ramos-Cormenzana A. Antimicrobial activity of natural and semisynthetic diterpenoids from Sideritis spp. Microbios. 77:1995;7-13.
32. Sepalla A.J., Wikstrom M.K.F., Saris N.E.L. Damping of mitochondrial volume oscillations by propranolol and related compounds. Chance B., Pye E.K., Ghosh A.K., Hess B. Biol. Biochem. Oscillators. 1973;115-124 Academic Press, New York.
33. Singer T.P. Glick D. Methods of Biochemical Analysis. 22:1974;123 Wiley, New York.
34. Somlo M. Induction des lactico-cytochrome c reductases (D- et L-) de la levure aerobie par les lactates (D- et L-). Biochim. Biophys. Acta. 97:1965;183-201.
35. Strecker H.J. L-Glutamic dehydrogenase from liver. Methods Enzymol. 2:1955;220-221.
36. Toskulkao C., Sutheerawattananon M., Piyachaturawat P. Inhibitory effect of steviol, a metabolite of stevioside, on glucose absorption in everted hamster intestine in vitro. Toxicol. Lett. 80:1995;153-159.
37. Vignais P.V., Duee E.D., Vignais P.M., Huet J. Effects of atractylgenin and its structural analogues on oxidative phosphorylation and on the translocation of adenine nucleotide in mitochondria. Biochim. Biophys. Acta. 118:1966;465-483.
38. Voss D.O., Campelo A.P., Bacila M. The respiratory chain and oxidative phosphorylation of rat brain mitochondria. Biochem. Biophys. Res. Commun. 4:1961;48-51.
39. Wallace K.B., Starkov A. Mitochondrial targets of drug toxicity. Ann. Rev. Pharmacol. Toxicol. 40:2000;353-388.
40. Wingard R.E., Brown J.P.J., Enderlin F.E., Dale J.A., Hale R.L., Seitz C.T. Intestinal degradation and absorption of the glycosidic sweetners stevioside and rebaudioside A. Experientia. 36:1980;519-520.
41. World Health Organization. Monographs on Selected Medicinal Plants, Vol 1. (1999) World Health Organization, Geneva.
42. Zhen Q.S., Ye X., Wei Z.J. Recent progress in research on Tripterygium: a male antifertility plant. Contraception. 51:1995;121-129.