Endothelial-cell-binding aptamer for coating of intracoronary stents

Journal of Invasive Cardiology

Volumn 22, Issue 10, 2010, Pages 481-487

  Strahm, Yvonne ^a,b   Flueckiger, Annina ^a   Billinger, Michael ^a   Meier, Pascal ^a   Mettler, Daniel ^a   Weisser, Susan ^a   Schaffner, Thomas ^b   Hess, Otto ^a  

^a BERN UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

cobalt chromium stent; endothelial cell binding aptamer; inflammation; neointimal proliferation; porcine overstretch model

Indexed keywords

APTAMER;

ANGIOCARDIOGRAPHY; ANIMAL EXPERIMENT; ARTERY INTIMA PROLIFERATION; ARTICLE; CONTROLLED STUDY; CORONARY STENT; GRANULOMA; HISTOLOGY; INFLAMMATION; INTIMA; MORPHOMETRICS; NONHUMAN; RESTENOSIS; TRANSLUMINAL CORONARY ANGIOPLASTY; TREATMENT DURATION;

ANIMALS; APTAMERS, NUCLEOTIDE; CHROMIUM ALLOYS; COATED MATERIALS, BIOCOMPATIBLE; CORONARY ANGIOGRAPHY; CORONARY RESTENOSIS; CORONARY STENOSIS; CORONARY VESSELS; ENDOTHELIAL CELLS; POLYMERS; SELEX APTAMER TECHNIQUE; STENTS; SUS SCROFA;

EID: 77958164904     PISSN: 10423931     EISSN: 15572501     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Serruys P W, Kutryk MJ, Ong AT. Coronary-artery stents. N Engl J Med 2006;354:483-495.
2. Schuehlen H, Kastrati A, Dirschinger J, et al. Intracoronary stenting and risk for major adverse cardiac events during the first month. Circulation 1998;98:104-111.
3. Kastrati A, Mehilli J, Pache J, et al. Analysis of 14 trials comparing sirolimuseluting stents with bare-metal stents. N Engl J Med 2007;356:1030-1039.
4. Kastrati A, Dibra A, Eberle S, et al. Sirolimus-eluting stents vs paclitaxel-eluting stents in patients with coronary artery disease: Meta-analysis of randomized trials. JAMA 2005;294:819-825.
5. Stone GW, Moses J W, Ellis SG, et al. Safety and efficacy of sirolimus-and paclitaxel-eluting coronary stents. N Engl J Med 2007;356:998-1008.
6. Serruys P W, Sianos G, Abizaid A, et al. The effect of variable dose and release kinetics on neointimal hyperplasia using a novel paclitaxel-eluting stent platform: The Paclitaxel In-Stent Controlled Elution Study (PISCES). J Am Coll Cardiol 2005;46:253-260.
7. Farb A, Burke A P, Kolodgie FD, Virmani R. Pathological mechanisms of fatal late coronary stent thrombosis in humans. Circulation 2003;108:1701-1706.
8. Virmani R, Guagliumi G, Farb A, et al. Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: Should we be cautious? Circulation 2004;109:701-705.
9. Joner M, Finn AV, Farb A, et al. Pathology of drug-eluting stents in humans: Delayed healing and late thrombotic risk. J Am Coll Cardiol 2006;48:193-202.
10. Aoki J, Serruys PW, van Beusekom H, et al. Endothelial progenitor cell capture by stents coated with antibody against CD34: The HEALING-FIM (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth-First In Man) Registry. J Am Coll Cardiol 2005;45:1574-1579.
11. Hoffmann J, Paul A, Harwardt M, et al. Immobilized DNA aptamers used as potent attractors for porcine endothelial precursor cells. J Biomed Mater Res A 2008;84:614-621.
12. Nimjee SM, Rusconi C P, Harrington RA, Sullenger BA. The potential of aptamers as anticoagulants. Trends Cardiovasc Med 2005;15:41-45.
13. Gold L, Polisky B, Uhlenbeck O, Yarus M. Diversity of oligonucleotide functions. Annu Rev Biochem 1995;64:763-797.
14. Tucker CE, Chen LS, Judkins MB, et al. Detection and plasma pharmacokinetics of an antivascular endothelial growth factor oligonucleotide-aptamer (NX1838) in rhesus monkeys. J Chromatogr B Biomed Sci Appl 1999;732:203-212.
15. Windecker S, Mayer I, De Pasquale G, et al. Working Group on Novel Surface Coating of Biomedical Devices (SCOL). Stent coating with titanium-nitride-oxide for reduction of neointimal hyperplasia. Circulation 2001;104:928-933.
16. Flueckiger A, Strahm Y, Billinger M, et al. Intimal proliferation and restenosis in paclitaxel-eluting stents with aminoparylene as carrier substance in swines. J Invasive Cardiol 2009;21:128-132.
17. Frey D, Billinger M, Meier P, et al. Endothelialization of sirolimus-eluting stents with slow and extended drug release in the porcine overstretch model. J Invasive Cardiol 2008;20:631-634.
18. Nebeker JR, Virmani R, Bennet CL, et al. Hypersensitivity cases associated with drug-eluting coronary stents: A review of available cases from the Research on Adverse Drug Events and Reports (RADAR) project. J Am Coll Cardiol 2006;47:175-181.
19. Szmitko PE, Kutryk MJ, Stewart DJ, et al. Endothelial progenitor cell-coated stents under scrutiny. Can J Cardiology 2006;22:1117-1119.
20. Taljaard M, Ward MR, Kutryk MJ, et al. Rationale and design of Enhanced Angiogenic Cell Therapy in Acute Myocardial Infarction (ENACT-AMI): The first randomized placebo-controlled trial of enhanced progenitor cell therapy for acute myocardial infarction. Am Heart J 2010;159:354-360.
21. Van der Giessen WJ, Lincoff AM, Schwartz RS, et al. Marked inflammatory sequelae to implantation of biodegradable and non-biodegradable polymers in porcine coronary arteries. Circulation 1996;94:1690-1697.