Intermittent subglottic secretion drainage and ventilator-associated pneumonia: A multicenter trial

American Journal of Respiratory and Critical Care Medicine

Volumn 182, Issue 7, 2010, Pages 910-917

  Lacherade, Jean Claude ^a   De Jonghe, Bernard ^a   Guezennec, Pierre ^b   Debbat, Karim ^c   Hayon, Jan ^a   Monsel, Antoine ^a   Fangio, Pascal ^a   De Vecchi, Corinne Appere ^a   Ramaut, Cédric ^a   Outin, Hervé ^a   Bastuji Garin, Sylvie ^d,e  

^a CENTRE HOSPITALIER INTERCOMMUNAL   (France)

^b CENTRE HOSPITALIER DE VERSAILLES   (France)

^c Avignon Hospital Center   (France)

^d UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^e HENRI MONDOR HOSPITAL   (France)

Author keywords

Critically ill patients; Intensive care; Prevention; Subglottic secretions drainage; Ventilator associated pneumonia

Indexed keywords

ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENDOTRACHEAL INTUBATION; ENDOTRACHEAL TUBE; FEMALE; HUMAN; INCIDENCE; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SUBGLOTTIC SECRETION DRAINAGE; SURGICAL DRAINAGE; THORAX RADIOGRAPHY; VENTILATOR ASSOCIATED PNEUMONIA; FRANCE; GLOTTIS; INSTRUMENTATION; KAPLAN MEIER METHOD; METHODOLOGY; MIDDLE AGED; SECRETION; WOUND DRAINAGE;

AGED; DRAINAGE; FEMALE; FRANCE; GLOTTIS; HUMANS; INTENSIVE CARE UNITS; INTUBATION, INTRATRACHEAL; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED;

EID: 77958162057     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200906-0838OC     Document Type: Article

References (38)

1. Chastre J, Fagon JY. Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002;165:867-903.
2. Klompas M. Does this patient have ventilator-associated pneumonia? JAMA 2007;297:1583-1593.
3. American Thoracic Society, Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005;171:388-416.
4. Oikkonen M, Aromaa U. Leakage of fluid around low-pressure tracheal tube cuffs. Anaesthesia 1997;52:567-569.
5. Petring OU, Adelhoj B, Jensen BN, Pedersen NO, Lomholt N. Prevention of silent aspiration due to leaks around cuffs of endotracheal tubes. Anesth Analg 1986;65:777-780.
6. Young PJ, Rollinson M, Downward G, Henderson S. Leakage of fluid past the tracheal tube cuff in a benchtop model. Br J Anaesth 1997;78:557-562.
7. Mahul P, Auboyer C, Jospe R, Ros A, Guerin C, el Khouri Z, Galliez M, Dumont A, Gaudin O. Prevention of nosocomial pneumonia in intubated patients: respective role of mechanical subglottic secretions drainage and stress ulcer prophylaxis. Intensive Care Med 1992;18:20-25.
8. Smulders K, van der Hoeven H, Weers-Pothoff I, Vandenbroucke-Grauls C. A randomized clinical trial of intermittent subglottic secretion drainage in patients receiving mechanical ventilation. Chest 2002;121:858-862.
9. Rello J, Sonora R, Jubert P, Artigas A, Rue M, Valles J. Pneumonia in intubated patients: role of respiratory airway care. Am J Respir Crit Care Med 1996;154:111-115.
10. Bouza E, Jesus Perez M, Munoz P, Rincon C, Maria Barrio J, Hortal J. Continuous aspiration of subglottic secretions (CASS) in the prevention of ventilator-associated pneumonia in the postoperative period of major heart surgery. Chest 2008;134:938-946.
11. Kollef MH, Skubas NJ, Sundt TM. A randomized clinical trial of continuous aspiration of subglottic secretions in cardiac surgery patients. Chest 1999;116:1339-1346.
12. Valles J, Artigas A, Rello J, Bonsoms N, Fontanals D, Blanch L, Fernandez R, Baigorri F, Mestre J. Continuous aspiration of subglottic secretions in preventing ventilator-associated pneumonia. Ann Intern Med 1995;122:179-186.
13. Dezfulian C, Shojania K, Collard HR, Kim HM, Matthay MA, Saint S. Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis. Am J Med 2005;118:11-18.
14. Dodek P, Keenan S, Cook D, Heyland D, Jacka M, Hand L, Muscedere J, Foster D, Mehta N, Hall R, et al. Evidence-based clinical practice guideline for the prevention of ventilator-associated pneumonia. Ann Intern Med 2004;141:305-313.
15. Tablan OC, Anderson LJ, Besser R, Bridges C, Hajjeh R. Guidelines for preventing health-care - associated pneumonia, 2003: recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee. MMWR Recomm Rep 2004;53:1-36.
16. Muscedere J, Dodek P, Keenan S, Fowler R, Cook D, Heyland D. Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: prevention. J Crit Care 2008;23:126-137. (Pubitemid 351400352)
17. Coffin SE, Klompas M, Classen D, Arias K, Podgorny K, Anderson DJ, Burstin H, Calfee DP. Strategies to prevent ventilator-associated pneumonia in acute care hospitals. Infect Control Hosp Epidemiol 2008;29:S31-S40.
18. Cook D, Ricard JD, Reeve B, Randall J, Wigg M, Brochard L, Dreyfuss D. Ventilator circuit and secretion management strategies: a Franco-Canadian survey. Crit Care Med 2000;28:3547-3554.
19. Berra L, De Marchi L, Panigada M, Yu ZX, Baccarelli A, Kolobow T. Evaluation of continuous aspiration of subglottic secretion in an in vivo study. Crit Care Med 2004;32:2071-2078.
20. Lacherade JC, Guezennec P, Debbat K, Hayon J, Monsel A, De Jonghe B, Fangio P, Appere de Vecchi C, Outin H, Bastuji-Garin S. Impact of subglottic secretions drainage on ventilator-associated pneumonia: a randomized multicentre trial [abstract]. Intensive Care Med 2008;34:S102.
21. Yanagawa Y, Sakamoto T, Okada Y. Recovery from a psychotropic drug overdose tends to depend on the time from ingestion to arrival, the Glasgow Coma Scale, and a sign of circulatory insufficiency on arrival. Am J Emerg Med 2007;25:757-761.
22. Keenan SP, Dodek P, Martin C, Priestap F, Norena M, Wong H. Variation in length of intensive care unit stay after cardiac arrest: where you are is as important as who you are. Crit Care Med 2007;35:836-841.
23. Nolan JP, Laver SR, Welch CA, Harrison DA, Gupta V, Rowan K. Outcome following admission to UK intensive care units after cardiac arrest: a secondary analysis of the ICNARC Case Mix Programme Database. Anaesthesia 2007;62:1207-1216.
24. Lacherade JC, Auburtin M, Cerf C, Van de Louw A, Soufir L, Rebufat Y, Rezaiguia S, Ricard JD, Lellouche F, Brun-Buisson C, et al. Impact of humidification systems on ventilator-associated pneumonia: a randomized multicenter trial. Am J Respir Crit Care Med 2005;172:1276-1282.
25. Trouillet JL, Chastre J, Vuagnat A, Joly-Guillou ML, Combaux D, Dombret MC, Gibert C. Ventilator-associated pneumonia caused by potentially drug-resistant bacteria. Am J Respir Crit Care Med 1998;157:531-539.
26. Pham LH, Brun-Buisson C, Legrand P, Rauss A, Verra F, Brochard L, Lemaire F. Diagnosis of nosocomial pneumonia in mechanically ventilated patients: comparison of a plugged telescoping catheter with the protected specimen brush. Am Rev Respir Dis 1991;143:1055-1061.
27. Fartoukh M, Maitre B, Honore S, Cerf C, Zahar JR, Brun-Buisson C. Diagnosing pneumonia during mechanical ventilation: the clinical pulmonary infection score revisited. Am J Respir Crit Care Med 2003;168:173-179.
28. Lorente L, Lecuona M, Jimenez A, Mora ML, Sierra A. Influence of an endotracheal tube with polyurethane cuff and subglottic secretion drainage on pneumonia. Am J Respir Crit Care Med 2007;176:1079-1083.
29. O'Neal PV, Munro CL, Grap MJ, Rausch SM. Subglottic secretion viscosity and evacuation efficiency. Biol Res Nurs 2007;8:202-209.
30. Greene R, Thompson S, Jantsch HS, Teplick R, Cullen DJ, Greene EM, Whitman GJ, Hulka CA, Llewellyn HJ. Detection of pooled secretions above endotracheal-tube cuffs: value of plain radiographs in sheep cadavers and patients. AJR Am J Roentgenol 1994;163:1333-1337.
31. Depew CL, McCarthy MS. Subglottic secretion drainage: a literature review. AACN Adv Crit Care 2007;18:366-379.
32. Koeman M, van der Ven AJ, Hak E, Joore HC, Kaasjager K, de Smet AG, Ramsay G, Dormans TP, Aarts LP, de Bel EE, et al. Oral decontamination with chlorhexidine reduces the incidence of ventilator-associated pneumonia. Am J Respir Crit Care Med 2006;173:1348-1355.
33. Kollef MH, Afessa B, Anzueto A, Veremakis C, Kerr KM, Margolis BD, Craven DE, Roberts PR, Arroliga AC, Hubmayr RD, et al. Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial. JAMA 2008;300:805-813.
34. Meyer E, Schwab F, Jonas D, Rueden H, Gastmeier P, Daschner FD. Surveillance of antimicrobial use and antimicrobial resistance in intensive care units (SARI). 1. Antimicrobial use in German intensive care units. Intensive Care Med 2004;30:1089-1096.
35. Walther SM, Erlandsson M, Burman LG, Cars O, Gill H, Hoffman M, Isaksson B, Kahlmeter G, Lindgren S, Nilsson L, et al. Antibiotic prescription practices, consumption and bacterial resistance in a cross section of Swedish intensive care units. Acta Anaesthesiol Scand 2002;46:1075-1081.
36. Montori VM, Devereaux PJ, Adhikari NK, Burns KE, Eggert CH, Briel M, Lacchetti C, Leung TW, Darling E, Bryant DM, et al. Randomized trials stopped early for benefit: a systematic review. JAMA 2005;294:2203-2209.
37. Shorr A, O'Malley P. Continuous subglottic suctioning for the prevention of ventilator-associated pneumonia: potential economic implications. Chest 2001;119:228-235.
38. Girou E, Buu-Hoi A, Stephan F, Novara A, Gutmann L, Safar M, Fagon JY. Airway colonisation in long-term mechanically ventilated patients: effect of semi-recumbent position and continuous subglottic suctioning. Intensive Care Med 2004;30:225-233.