-
1
-
-
0015515283
-
Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity
-
Giblett ER, Anderson JE, Cohen F, Pollara B, Meuwissen HJ. Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity. Lancet. 1972;2(7786):1067-1069.
-
(1972)
Lancet
, vol.2
, Issue.7786
, pp. 1067-1069
-
-
Giblett, E.R.1
Anderson, J.E.2
Cohen, F.3
Pollara, B.4
Meuwissen, H.J.5
-
3
-
-
0017639365
-
Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleosidase kinase(s)
-
Carson DA, Kaye J, Seegmiller JE. Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleosidase kinase(s). Proc Natl Acad Sci U S A. 1977;74(12):5677-5681.
-
(1977)
Proc Natl Acad Sci U S A
, vol.74
, Issue.12
, pp. 5677-5681
-
-
Carson, D.A.1
Kaye, J.2
Seegmiller, J.E.3
-
4
-
-
3042870116
-
Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo
-
DOI 10.1073/pnas.77.11.6865
-
Carson DA, Wasson DB, Kaye J, et al. Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo. Proc Natl Acad Sci U S A. 1980;77(11):6865-6869. (Pubitemid 11219046)
-
(1980)
Proceedings of the National Academy of Sciences of the United States of America
, vol.77
, Issue.11 I
, pp. 6865-6869
-
-
Carson, D.A.1
Wasson, D.B.2
Kaye, J.3
-
5
-
-
0015366370
-
Synthesis and biological activity of selected 2,6-disubstituted-(2-deoxy- and -D-erythro-pentofuranosyl) purines
-
Christensen LF, Broom AD, Robins MJ, Bloch A. Synthesis and biological activity of selected 2,6-disubstituted-(2-deoxy- and -D-erythro-pentofuranosyl) purines. J Med Chem. 1972;15(7):735-739.
-
(1972)
J Med Chem
, vol.15
, Issue.7
, pp. 735-739
-
-
Christensen, L.F.1
Broom, A.D.2
Robins, M.J.3
Bloch, A.4
-
6
-
-
0037362951
-
Extended follow-up of patients with hairy cell leukemia after treatment with cladribine
-
DOI 10.1200/JCO.2003.05.093
-
Goodman GR, Burian C, Koziol JA, Saven A. Extended follow-up of patients with hairy cell leukemia after treatment with cladribine. J Clin Oncol. 2003;21(5):891-896. (Pubitemid 46606450)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.5
, pp. 891-896
-
-
Goodman, G.R.1
Burian, C.2
Koziol, J.A.3
Saven, A.4
-
7
-
-
0024263350
-
Sodium-dependent nucleoside transport in mouse intestinal epithelial cells
-
Vijayalakshmi DA, Belt JA. Sodium-dependent nucleoside transport in mouse intestinal epithelial cells. J Biol Chem. 1988;263(36):19419-19423.
-
(1988)
J Biol Chem
, vol.263
, Issue.36
, pp. 19419-19423
-
-
Vijayalakshmi, D.A.1
Belt, J.A.2
-
8
-
-
0026799508
-
Cladribine (2-chlorodeoxyadenosine)
-
Beutler E. Cladribine (2-chlorodeoxyadenosine). Lancet. 1992;340(8825):952-956.
-
(1992)
Lancet
, vol.340
, Issue.8825
, pp. 952-956
-
-
Beutler, E.1
-
9
-
-
68049128257
-
Cladribine: Not just another purine analogue?
-
Spurgeon S, Yu M, Phillips JD, Epner EM. Cladribine: not just another purine analogue? Expert Opin Investig Drugs. 2009;18(8):1169-1181.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, Issue.8
, pp. 1169-1181
-
-
Spurgeon, S.1
Yu, M.2
Phillips, J.D.3
Epner, E.M.4
-
10
-
-
0020612685
-
Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes
-
Carson DA, Wasson DB, Taetle R, Yu A. Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes. Blood. 1983;62(4):737-743.
-
(1983)
Blood
, vol.62
, Issue.4
, pp. 737-743
-
-
Carson, D.A.1
Wasson, D.B.2
Taetle, R.3
Yu, A.4
-
11
-
-
0027525929
-
Relationship of deoxycytidine kinase and cytoplasmic 5′- nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine
-
Kawasaki J, Carera CJ, Piro LD, Saven A, Kipps T, Carson DA. Relationship of deoxycytidine kinase and cytoplasmic 5′-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine. Blood. 1993;81(3):597-601.
-
(1993)
Blood
, vol.81
, Issue.3
, pp. 597-601
-
-
Kawasaki, J.1
Carera, C.J.2
Piro, L.D.3
Saven, A.4
Kipps, T.5
Carson, D.A.6
-
12
-
-
0023792806
-
Deoxycytidine kinase is constitutively expressed in human lymphocytes: Consequences for compartmentation effects, unscheduled DNA synthesis, and viral replication in resting cells
-
Arner ES, Flygar M, Bohman C, Wallstrom B, Eriksson S. Deoxycytidine kinase is constitutively expressed in human lymphocytes: consequences for compartmentation effects, unscheduled DNA synthesis, and viral replication in resting cells. Exp Cell Res. 1988;178(2):335-342.
-
(1988)
Exp Cell Res
, vol.178
, Issue.2
, pp. 335-342
-
-
Arner, E.S.1
Flygar, M.2
Bohman, C.3
Wallstrom, B.4
Eriksson, S.5
-
13
-
-
0141535442
-
Pharmacological basis for cladribine resistance
-
Lotfi K, Juliusson G, Albertioni F. Pharmacological basis for cladribine resistance. Leuk Lymphoma. 2003;44(10):1705-1712.
-
(2003)
Leuk Lymphoma
, vol.44
, Issue.10
, pp. 1705-1712
-
-
Lotfi, K.1
Juliusson, G.2
Albertioni, F.3
-
14
-
-
0037437762
-
Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance
-
Månsson E, Flordal E, Liliemark J. Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance. Biochem Pharmacol. 2003;65(2):237-247.
-
(2003)
Biochem Pharmacol
, vol.65
, Issue.2
, pp. 237-247
-
-
Månsson, E.1
Flordal, E.2
Liliemark, J.3
-
16
-
-
0022003367
-
Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes
-
Seto S, Carrera CJ, Kubota M, Wasson DB, Carson DA. Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes. J Clin Invest. 1985;75(2):377-383.
-
(1985)
J Clin Invest
, vol.75
, Issue.2
, pp. 377-383
-
-
Seto, S.1
Carrera, C.J.2
Kubota, M.3
Wasson, D.B.4
Carson, D.A.5
-
17
-
-
0022492499
-
DNA strand breaks, NAD metabolism and programmed cell death
-
Carson DA, Seto C, Wasson DB, Carrera CJ. DNA strand breaks, NAD metabolism and programmed cell death. Exp Cell Res. 1986;164(2):273-281.
-
(1986)
Exp Cell Res
, vol.164
, Issue.2
, pp. 273-281
-
-
Carson, D.A.1
Seto, C.2
Wasson, D.B.3
Carrera, C.J.4
-
18
-
-
0035503898
-
Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria
-
Marzo I, Pérez-Galán P, Giraldo P. Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria. Biochem J. 2001;359(Pt 3):537-546.
-
(2001)
Biochem J
, vol.359
, Issue.PART 3
, pp. 537-546
-
-
Marzo, I.1
Pérez-Galán, P.2
Giraldo, P.3
-
19
-
-
0028365118
-
Template 2-chloro-2'-deoxyadenosine monophosphate inhibits in vitro DNA synthesis
-
Hentosh P, Grippo P. Template 2-chloro-2-deoxyadenosine monophosphate inhibits in vitro DNA synthesis. Mol Pharmacol. 1994;45(5):955-961. (Pubitemid 24155786)
-
(1994)
Molecular Pharmacology
, vol.45
, Issue.5
, pp. 955-961
-
-
Hentosh, P.1
Grippo, P.2
-
20
-
-
0032483010
-
Induction of an apoptotic program in cell-free extracts by 2-chloro-2-deoxyadenosine 5-triphosphate and cytochrome c
-
Leoni LM, Chao Q, Cottam HB, et al. Induction of an apoptotic program in cell-free extracts by 2-chloro-2-deoxyadenosine 5-triphosphate and cytochrome c. Proc Natl Acad Sci U S A. 1998;95(16):9567-9571.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.16
, pp. 9567-9571
-
-
Leoni, L.M.1
Chao, Q.2
Cottam, H.B.3
-
21
-
-
0034614551
-
Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway
-
Genini D, Budihardjo I, Plunkett W, et al. Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway. J Biol Chem. 2000;275(1):29-34.
-
(2000)
J Biol Chem
, vol.275
, Issue.1
, pp. 29-34
-
-
Genini, D.1
Budihardjo, I.2
Plunkett, W.3
-
22
-
-
0025935563
-
On the pharmacokinetics of 2-chloro-2-deoxyadenosine in humans
-
Liliemark J, Juliusson G. On the pharmacokinetics of 2-chloro-2- deoxyadenosine in humans. Cancer Res. 1991;51(20):5570-5572.
-
(1991)
Cancer Res
, vol.51
, Issue.20
, pp. 5570-5572
-
-
Liliemark, J.1
Juliusson, G.2
-
23
-
-
0033949050
-
Pharmacokinetics of 2-chloro-2'-deoxyadenosine administered subcutaneously or by continuous intravenous infusion
-
Sonderegger T, Betticher DC, Cerny T, Lauterburg BH. Pharmacokinetics of 2-CDA administered subcutaneously or by continuous intravenous infusion. Cancer Chemother Pharmacol. 2000;46(1):40-42. (Pubitemid 30432173)
-
(2000)
Cancer Chemotherapy and Pharmacology
, vol.46
, Issue.1
, pp. 40-42
-
-
Sonderegger, T.1
Betticher, D.C.2
Cerny, T.3
Lauterburg, B.H.4
-
24
-
-
0027056958
-
On the bioavailability of oral and subcutaneous 2-chloro-2′- deoxyadenosine in humans: Alternative routes of administration
-
Liliemark J, Albertioni F, Hassan M, Juliusson G. On the bioavailability of oral and subcutaneous 2-chloro-2′-deoxyadenosine in humans: alternative routes of administration. J Clin Oncol. 1992;10(10):1514-1518.
-
(1992)
J Clin Oncol
, vol.10
, Issue.10
, pp. 1514-1518
-
-
Liliemark, J.1
Albertioni, F.2
Hassan, M.3
Juliusson, G.4
-
25
-
-
0027468268
-
2-Chlorodeoxyadenosine dose escalation in non-hematologic malignancies
-
Saven A, Kawasaki H, Carrera CJ. 2-Chlorodeoxyadenosine dose escalation in non-hematologic malignancies. J Clin Oncol. 1993;11(4):671-678.
-
(1993)
J Clin Oncol
, vol.11
, Issue.4
, pp. 671-678
-
-
Saven, A.1
Kawasaki, H.2
Carrera, C.J.3
-
26
-
-
0026590267
-
2-Chlorodeoxyadenosine treatment of low-grade lymphomas
-
Kay AC, Saven A, Carrera CJ, et al. 2-Chlorodeoxyadenosine treatment of low-grade lymphomas. J Clin Oncol. 1992;10(3):371-377.
-
(1992)
J Clin Oncol
, vol.10
, Issue.3
, pp. 371-377
-
-
Kay, A.C.1
Saven, A.2
Carrera, C.J.3
-
27
-
-
10244270720
-
High response rates with short infusional 2-chlorodeoxyadenosine in de novo and relapsed low-grade lymphoma
-
Morton J, Taylor K, Bunce I, et al. High response rates with short infusional 2-chlorodeoxyadenosine in de novo and relapsed low-grade lymphoma. Br J Haematol. 1996;95(1):110-115.
-
(1996)
Br J Haematol
, vol.95
, Issue.1
, pp. 110-115
-
-
Morton, J.1
Taylor, K.2
Bunce, I.3
-
28
-
-
8544229924
-
Activity of 2-chlorodeoxyadenosine (Cladribine) in 2-hour intravenous infusion in 94 previously treated patients with low grade non-Hodgkin's lymphoma
-
Robak T, Gora-Tybor J, Krykowski E, et al. Activity of 2-chlorodeoxyadenosine (Cladribine) in 2-hour intravenous infusion in 94 previously treated patients with low grade non-Hodgkin's lymphoma. Leuk Lymphoma. 1997;26(1):99-105.
-
(1997)
Leuk Lymphoma
, vol.26
, Issue.1
, pp. 99-105
-
-
Robak, T.1
Gora-Tybor, J.2
Krykowski, E.3
-
29
-
-
0027391309
-
2-Chlorodeoxyadenosine: Evaluation of a novel predominantly lymphocyte selective agent in lymphoid malignancies
-
Hickish T, Serafinowski P, Cunningham D, et al. 2-Chlorodeoxyadenosine: evaluation of a novel predominantly lymphocyte selective agent in lymphoid malignancies. Br J Cancer. 1993;67(1):139-143.
-
(1993)
Br J Cancer
, vol.67
, Issue.1
, pp. 139-143
-
-
Hickish, T.1
Serafinowski, P.2
Cunningham, D.3
-
30
-
-
0028218049
-
2-Chlorodeoxyadenosine is an active salvage therapy in advanced indolent non-Hodgkin's lymphoma
-
Hoffman M, Tallman MS, Hakimian D, et al. 2-Chlorodeoxyadenosine is an active salvage therapy in advanced indolent non-Hodgkin's lymphoma. J Clin Oncol. 1994;12(4):788-792.
-
(1994)
J Clin Oncol
, vol.12
, Issue.4
, pp. 788-792
-
-
Hoffman, M.1
Tallman, M.S.2
Hakimian, D.3
-
31
-
-
0030949196
-
Intermittent infusion of cladribine (CdA) in previously treated patients with low-grade non-Hodgkin's lymphoma
-
Liliemark J, Porwit A, Juliusson G. Intermittent infusion of cladribine (CdA) in previously treated patients with low-grade non-Hodgkin's lymphoma. Leuk Lymphoma. 1997;25(3):313-318.
-
(1997)
Leuk Lymphoma
, vol.25
, Issue.3
, pp. 313-318
-
-
Liliemark, J.1
Porwit, A.2
Juliusson, G.3
-
32
-
-
0032031650
-
Long term follow-up and late complications of 2-chlorodeoxyadenosine in previously treated advanced, indolent non-Hodgkin's lymphoma
-
Kong LR, Huang CF, Hakimian D, et al. Long term follow-up and late complications of 2-chlorodeoxyadenosine in previously treated advanced, indolent non-Hodgkin's lymphoma. Cancer. 1998;82(5):957-964.
-
(1998)
Cancer
, vol.82
, Issue.5
, pp. 957-964
-
-
Kong, L.R.1
Huang, C.F.2
Hakimian, D.3
-
33
-
-
0032402168
-
Cladribine in the treatment of advanced relapsed or refractory low and intermediate grade non-Hodgkin's lymphoma
-
Tupule A, Schiller G, Harvey-Buchanan LA, et al. Cladribine in the treatment of advanced relapsed or refractory low and intermediate grade non-Hodgkin's lymphoma. Cancer. 1998;83(11):2370-2376.
-
(1998)
Cancer
, vol.83
, Issue.11
, pp. 2370-2376
-
-
Tupule, A.1
Schiller, G.2
Harvey-Buchanan, L.A.3
-
34
-
-
0034096015
-
Fludarabine and cladribine in relapsed refractory low-grade non-Hodgkin's lymphoma: A Phase II randomized study
-
Tondini C, Balzarotti M, Rampinelli I, et al. Fludarabine and cladribine in relapsed refractory low-grade non-Hodgkin's lymphoma: a Phase II randomized study. Ann Oncol. 2000;11(2):231-233.
-
(2000)
Ann Oncol
, vol.11
, Issue.2
, pp. 231-233
-
-
Tondini, C.1
Balzarotti, M.2
Rampinelli, I.3
-
35
-
-
6944230907
-
Durable response but prolonged cytopenias after cladribine treatment in relapsed patients with indolent non-Hodgkin's lymphomas: Results of a Japanese phase II study
-
Ogura M, Morishima Y, Kobayashi Y, et al. Durable response but prolonged cytopenias after cladribine treatment in relapsed patients with indolent non-Hodgkin's lymphomas: results of a Japanese phase II study. Int J Hematol. 2004;80(3):267-277.
-
(2004)
Int J Hematol
, vol.80
, Issue.3
, pp. 267-277
-
-
Ogura, M.1
Morishima, Y.2
Kobayashi, Y.3
-
36
-
-
67449103121
-
Phase I/II and pharmacokinetic study of cladribine with 2-h infusion in Japanese patients with relapsed indolent B-cell lymphoma mostly pretreated with rituximab
-
Tobinai K, Watanabe T, Tanimoto K, et al. Phase I/II and pharmacokinetic study of cladribine with 2-h infusion in Japanese patients with relapsed indolent B-cell lymphoma mostly pretreated with rituximab. Cancer Sci. 2009;100(7):1344-1350.
-
(2009)
Cancer Sci
, vol.100
, Issue.7
, pp. 1344-1350
-
-
Tobinai, K.1
Watanabe, T.2
Tanimoto, K.3
-
37
-
-
2542466807
-
High incidence of complications after 2-chloro-2′-deoxyadenosine combined with cyclophosphamide in patients with advanced lymphoproliferative malignancies
-
Van Den Neste E, Michaux L, Layios N, et al. High incidence of complications after 2-chloro-2′-deoxyadenosine combined with cyclophosphamide in patients with advanced lymphoproliferative malignancies. Ann Hematol. 2004;83(6):356-363.
-
(2004)
Ann Hematol
, vol.83
, Issue.6
, pp. 356-363
-
-
Van Den Neste, E.1
Michaux, L.2
Layios, N.3
-
38
-
-
0030013103
-
Cladribine and mitoxantrone dose escalation in indolent non-Hodgkin's lymphoma
-
Saven A, Lee T, Kosty MP, et al. Cladribine and mitoxantrone dose escalation in indolent non Hodgkin's lymphoma. J Clin Oncol. 1996;14(7)2139-2144. (Pubitemid 26230117)
-
(1996)
Journal of Clinical Oncology
, vol.14
, Issue.7
, pp. 2139-2144
-
-
Saven, A.1
Lee, T.2
Kosty, M.3
Piro, L.4
-
39
-
-
0345238896
-
Cladribine with cyclophosphamide and prednisone in the management of low-grade lymphoproliferative malignancies
-
Laurencet FM, Zulian GB, Guetty-Alberto M, Iten PA, Betticher DC, Alberto P. Cladribine with cyclophosphamide and prednisone in the management of low-grade lymphoproliferative malignancies. Br J Cancer. 1999;79(7):1215-1219.
-
(1999)
Br J Cancer
, vol.79
, Issue.7
, pp. 1215-1219
-
-
Laurencet, F.M.1
Zulian, G.B.2
Guetty-Alberto, M.3
Iten, P.A.4
Betticher, D.C.5
Alberto, P.6
-
40
-
-
0032982488
-
Combination regimen of 2-chlorodeoxyadenosine (cladribine), mitoxantrone and dexamethasone (CMD) in the treatment of refractory and recurrent low grade non-Hodgkin's lymphoma
-
Robak T, Gora-Tybor J, Urbańska-Ryś H, Krykowski E. Combination regimen of 2-chlorodeoxyadenosine (cladribine), mitoxantrone and dexamethasone (CMD) in the treatment of refractory and recurrent low grade non-Hodgkin's lymphoma. Leuk Lymphoma. 1999;32(3):359-363.
-
(1999)
Leuk Lymphoma
, vol.32
, Issue.3
, pp. 359-363
-
-
Robak, T.1
Gora-Tybor, J.2
Urbańska-Ryś, H.3
Krykowski, E.4
-
41
-
-
0036024588
-
Reduced-dose cladribine (2-CdA) plus mitoxantrone is effective in the treatment of mantle-cell and low-grade non-Hodgkin's lymphoma
-
Rummel MJ, Chow KU, Karakas T, et al. Reduced-dose cladribine (2-CdA) plus mitoxantrone is effective in the treatment of mantle-cell and low-grade non-Hodgkin's lymphoma. Eur J Cancer. 2002;38(13):1739-1746.
-
(2002)
Eur J Cancer
, vol.38
, Issue.13
, pp. 1739-1746
-
-
Rummel, M.J.1
Chow, K.U.2
Karakas, T.3
-
42
-
-
1842588045
-
Rituximab followed by cladribine in the treatment of heavily pretreated patients with indolent lymphoid malignancies
-
Robak T, Smolewski P, Urbanska-Rys H, Gora-Tybor J, Blonski JZ, Kasznicki M. Rituximab followed by cladribine in the treatment of heavily pretreated patients with indolent lymphoid malignancies. Leuk Lymphoma. 2004;45(5):937-944.
-
(2004)
Leuk Lymphoma
, vol.45
, Issue.5
, pp. 937-944
-
-
Robak, T.1
Smolewski, P.2
Urbanska-Rys, H.3
Gora-Tybor, J.4
Blonski, J.Z.5
Kasznicki, M.6
-
43
-
-
33749600951
-
Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma
-
Robak T, Smolewski P, Cebula B, et al. Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma. Cancer. 2006;107(7):1542-1550.
-
(2006)
Cancer
, vol.107
, Issue.7
, pp. 1542-1550
-
-
Robak, T.1
Smolewski, P.2
Cebula, B.3
-
44
-
-
33845805249
-
The multicenter trial SAKK 37/95 of cladribine, cyclophosphamide and prednisone in the treatment of chronic lymphocytic leukemias and low-grade non-Hodgkin's lymphomas
-
Laurencet F, Ballabeni P, Rufener B, et al. The multicenter trial SAKK 37/95 of cladribine, cyclophosphamide and prednisone in the treatment of chronic lymphocytic leukemias and low-grade non-Hodgkin's lymphomas. Acta Haematol. 2007;117(1):40-47.
-
(2007)
Acta Haematol
, vol.117
, Issue.1
, pp. 40-47
-
-
Laurencet, F.1
Ballabeni, P.2
Rufener, B.3
-
45
-
-
47249112184
-
Long-term results of the treatment of patients with mantle cell lymphoma with cladribine (2-CDA) alone (95-80-53) or 2-CDA and rituximab (N0189) in the North Central Cancer Treatment Group
-
Inwards DJ, Fishkin PA, Hillman DW, et al. Long-term results of the treatment of patients with mantle cell lymphoma with cladribine (2-CDA) alone (95-80-53) or 2-CDA and rituximab (N0189) in the North Central Cancer Treatment Group. Cancer. 2008;113(1):108-116.
-
(2008)
Cancer
, vol.113
, Issue.1
, pp. 108-116
-
-
Inwards, D.J.1
Fishkin, P.A.2
Hillman, D.W.3
-
46
-
-
33845586614
-
Prolonged follow-up after initial therapy with 2-chlorodeoxyadenosine in patients with indolent non-Hodgkin lymphoma: Results of Cancer and Leukemia Group B Study 9153
-
Cancer and Leukemia Group B Study 9153
-
Blum KA, Johnson JL, Niedzwiecki D, et al. Cancer and Leukemia Group B Study 9153. Prolonged follow-up after initial therapy with 2- chlorodeoxyadenosine in patients with indolent non-Hodgkin lymphoma: results of Cancer and Leukemia Group B Study 9153. Cancer. 2006;107(12):2817-2825.
-
(2006)
Cancer
, vol.107
, Issue.12
, pp. 2817-2825
-
-
Blum, K.A.1
Johnson, J.L.2
Niedzwiecki, D.3
-
47
-
-
0032829272
-
Intermittent 2-hour-infusion of cladribine as first-line therapy or in first relapse of progressive advanced low-grade and mantle cell lymphomas
-
Rummel MJ, Chow KU, Jäger E, et al. Intermittent 2-hour infusion of cladribine as first-line therapy or in first relapse of progressive advanced low-grade and mantle cell lymphomas. Leuk Lymphoma. 1999;35(1):129-138. (Pubitemid 29454410)
-
(1999)
Leukemia and Lymphoma
, vol.35
, Issue.1-2
, pp. 129-138
-
-
Rummel, M.J.1
Chow, K.U.2
Jager, E.3
Leimer, L.4
Hossfeld, D.K.5
Bergmann, L.6
Peters, H.D.7
Hansmann, M.L.8
Meyer, A.9
Hoelzer, D.10
Mitrou, P.S.11
-
48
-
-
0029163276
-
2-Chlorodeoxyadenosine activity in patients with untreated, indolent non-Hodgkin's lymphoma
-
Saven A, Emanuele S, Kosty M, Koziol J, Ellison D, Piro L. 2-Chlorodeoxyadenosine activity in patients with untreated, indolent non-Hodgkin's lymphoma. Blood. 1995;86(5):1710-1716.
-
(1995)
Blood
, vol.86
, Issue.5
, pp. 1710-1716
-
-
Saven, A.1
Emanuele, S.2
Kosty, M.3
Koziol, J.4
Ellison, D.5
Piro, L.6
-
49
-
-
10244219905
-
2-Chlorodeoxyadenosine (2-CDA) therapy in previously untreated patients with follicular stage III-IV non-Hodgkin's lymphoma
-
Betticher DC, Zucca E, von Rohr A, et al. 2-Chlorodeoxyadenosine (2-CDA) therapy in previously untreated patients with follicular stage III-IV non-Hodgkin's lymphoma. Ann Oncol. 1996;7(8):793-799.
-
(1996)
Ann Oncol
, vol.7
, Issue.8
, pp. 793-799
-
-
Betticher, D.C.1
Zucca, E.2
Von Rohr, A.3
-
50
-
-
0031047765
-
2-Chlorodeoxyadenosine as initial therapy for advanced low grade lymphomas
-
Canfield VA, Vose J, Guiney P, Bennett B, Nichols C. 2- Chlorodeoxyadenosine as initial therapy for advanced low grade lymphomas. Leuk Lymphoma. 1997;24(3):335-339. (Pubitemid 27101605)
-
(1997)
Leukemia and Lymphoma
, vol.24
, Issue.3-4
, pp. 335-339
-
-
Canfield, V.A.1
Vose, J.2
Guiney, P.3
Bennett, B.4
Nichols, C.5
-
51
-
-
0032167887
-
Efficacy and toxicity of 2-chlorodeoxyadenosine (Cladribine) - 2 h infusion for 5 days - as first-line treatment for advanced low grade non-Hodgkin's lymphoma
-
Fridrik MA, Jäger G, Kienzer HR, et al. Efficacy and toxicity of 2-chlorodeoxyadenosine (Cladribine) - 2 h infusion for 5 days - as first-line treatment for advanced low grade non-Hodgkin's lymphoma. Eur J Cancer. 1998;34(10):1560-1564.
-
(1998)
Eur J Cancer
, vol.34
, Issue.10
, pp. 1560-1564
-
-
Fridrik, M.A.1
Jäger, G.2
Kienzer, H.R.3
-
52
-
-
0031820075
-
Cladribine for untreated or early low-grade non-Hodgkin's lymphoma
-
Liliemark J, Martinsson U, Cavallin-Stahl E, et al. Cladribine for untreated or early low-grade non-Hodgkin's lymphoma. Leuk Lymphoma. 1998;30(5):573-581.
-
(1998)
Leuk Lymphoma
, vol.30
, Issue.5
, pp. 573-581
-
-
Liliemark, J.1
Martinsson, U.2
Cavallin-Stahl, E.3
-
53
-
-
0033034585
-
Treatment of mantle-cell lymphomas with intermittent two-hour infusion of cladribine as first-line therapy or in first relapse
-
DOI 10.1023/A:1008325212484
-
Rummel MJ, Chow KU, Jäger E, et al. Treatment of mantle-cell lymphomas with intermittent two-hour infusion of cladribine as first-line therapy or in first relapse. Ann Oncol. 1999;10(1):115-117. (Pubitemid 29090601)
-
(1999)
Annals of Oncology
, vol.10
, Issue.1
, pp. 115-117
-
-
Rummel, M.J.1
Chow, K.U.2
Jager, E.3
Hossfeld, D.K.4
Bergmann, L.5
Peters, H.-D.6
Hansmann, M.-L.7
Meyer, A.8
Hoelzer, D.9
Mitrou, P.S.10
-
54
-
-
0037106369
-
Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type with cladribine: A phase II study
-
Jäger G, Neumeister P, Brezinschek R, et al. Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type with cladribine: a phase II study. J Clin Oncol. 2002;20(18):3872-3877.
-
(2002)
J Clin Oncol
, vol.20
, Issue.18
, pp. 3872-3877
-
-
Jäger, G.1
Neumeister, P.2
Brezinschek, R.3
-
55
-
-
0035142895
-
Lack of efficacy of 2-chlorodeoxyadenosine in the treatment of splenic lymphoma with villous lymphocytes
-
Lefrère F, Hermine O, François S, et al. Lack of efficacy of 2-chlorodeoxyadenosine in the treatment of splenic lymphoma with villous lymphocytes. Leuk Lymphoma. 2000;40(1):113-117.
-
(2000)
Leuk Lymphoma
, vol.40
, Issue.1
, pp. 113-117
-
-
Lefrère, F.1
Hermine, O.2
François, S.3
-
56
-
-
0028173001
-
Primary therapy of Waldenström's macroglobulinemia with 2-chlorodeoxyadenosine
-
Dimopoulos MA, Kantarjian H, Weber D, et al. Primary therapy of Waldenström's macroglobulinemia with 2-chlorodeoxyadenosine. J Clin Oncol. 1994;12(12):2694-2698.
-
(1994)
J Clin Oncol
, vol.12
, Issue.12
, pp. 2694-2698
-
-
Dimopoulos, M.A.1
Kantarjian, H.2
Weber, D.3
-
57
-
-
0027492159
-
Treatment of Waldenstrom macroglobulinemia with 2-chlorodeoxyadenosine
-
Dimopoulos MA, Kantarjian H, Estey E, et al. Treatment of Waldenstrom macroglobulinemia with 2-chlorodeoxyadenosine. Ann Intern Med. 1993;118(3):195-198.
-
(1993)
Ann Intern Med
, vol.118
, Issue.3
, pp. 195-198
-
-
Dimopoulos, M.A.1
Kantarjian, H.2
Estey, E.3
-
58
-
-
1842406646
-
First-line treatment of Waldenstrom's disease with cladribine
-
DOI 10.1007/s002770050247
-
Fridrik MA, Jäger G, Baldinger C, Krieger O, Chott A, Bettelheim P. First-line treatment of Waldenström's disease with cladribine. Ann Hematol. 1997;74(1):7-10. (Pubitemid 27050902)
-
(1997)
Annals of Hematology
, vol.74
, Issue.1
, pp. 7-10
-
-
Fridrik, M.A.1
Jager, G.2
Baldinger, C.3
Krieger, O.4
Chott, A.5
Bettelheim, P.6
-
59
-
-
0031788917
-
Bolus administration of cladribine in the treatment of Waldenström macroglobulinaemia
-
Liu ES, Burian C, Miller WE, Saven A. Bolus administration of cladribine in the treatment of Waldenström macroglobulinaemia. Br J Haematol. 1998;103(3):690-695.
-
(1998)
Br J Haematol
, vol.103
, Issue.3
, pp. 690-695
-
-
Liu, E.S.1
Burian, C.2
Miller, W.E.3
Saven, A.4
-
60
-
-
0033017554
-
Effect of a 2-hour infusion of 2-chlorodeoxyadenosine in the treatment of refractory or previously untreated Waldenström's macroglobulinemia
-
Hellmann A, Lewandowski K, Zaucha JM, Bieniaszewska M, Halaburda K, Robak T. Effect of a 2-hour infusion of 2-chlorodeoxyadenosine in the treatment of refractory or previously untreated Waldenström's macroglobulinemia. Eur J Haematol. 1999;63(1):35-41.
-
(1999)
Eur J Haematol
, vol.63
, Issue.1
, pp. 35-41
-
-
Hellmann, A.1
Lewandowski, K.2
Zaucha, J.M.3
Bieniaszewska, M.4
Halaburda, K.5
Robak, T.6
-
61
-
-
48349121596
-
Randomized comparison of cladribine alone or in combination with cyclophosphamide, and cyclophosphamide, vincristine and prednisone in previously untreated low-grade B-cell non-Hodgkin lymphoma patients: Final report of the Polish Lymphoma Research Group
-
Kalinka-Warzocha E, Wajs J, Lech-Maranda E, et al. Randomized comparison of cladribine alone or in combination with cyclophosphamide, and cyclophosphamide, vincristine and prednisone in previously untreated low-grade B-cell non-Hodgkin lymphoma patients: final report of the Polish Lymphoma Research Group. Cancer. 2008;113(2):367-375.
-
(2008)
Cancer
, vol.113
, Issue.2
, pp. 367-375
-
-
Kalinka-Warzocha, E.1
Wajs, J.2
Lech-Maranda, E.3
-
62
-
-
33645730985
-
Phase III intergroup study of fludarabine phosphate compared with cyclophosphamide, vincristine, and prednisone chemotherapy in newly diagnosed patients with stage II and IV low-grade malignant non-Hodgkin's lymphoma
-
Hagenbeek A, Eghbali H, Monfardini S, et al. Phase III intergroup study of fludarabine phosphate compared with cyclophosphamide, vincristine, and prednisone chemotherapy in newly diagnosed patients with stage II and IV low-grade malignant non-Hodgkin's lymphoma. J Clin Oncol. 2006;24(10):1590-1596.
-
(2006)
J Clin Oncol
, vol.24
, Issue.10
, pp. 1590-1596
-
-
Hagenbeek, A.1
Eghbali, H.2
Monfardini, S.3
-
63
-
-
53749085410
-
Phase III study of R-CVP compared with cyclophosphamide, vincristine, and prednisone alone in patients with previously untreated advanced follicular lymphoma
-
Marcus R, Imrie K, Solal-Celigny P, et al. Phase III study of R-CVP compared with cyclophosphamide, vincristine, and prednisone alone in patients with previously untreated advanced follicular lymphoma. J Clin Oncol. 2008;26(28):4579-4586.
-
(2008)
J Clin Oncol
, vol.26
, Issue.28
, pp. 4579-4586
-
-
Marcus, R.1
Imrie, K.2
Solal-Celigny, P.3
-
64
-
-
34249985832
-
Waldenstrom macroglobulinemia
-
Vijay A, Gertz MA, Waldenstrom macroglobulinemia. Blood. 2007;109(12):5096-5103.
-
(2007)
Blood
, vol.109
, Issue.12
, pp. 5096-5103
-
-
Vijay, A.1
Gertz, M.A.2
-
65
-
-
58149350437
-
Update on treatment recommendations from the Fourth International Workshop on Waldenstrom's Macroglobulinemia
-
Dimopoulos MA, Gertz MA, Kastritis E, et al. Update on treatment recommendations from the Fourth International Workshop on Waldenstrom's Macroglobulinemia. J Clin Oncol. 2009;27(1):120-126.
-
(2009)
J Clin Oncol
, vol.27
, Issue.1
, pp. 120-126
-
-
Dimopoulos, M.A.1
Gertz, M.A.2
Kastritis, E.3
-
66
-
-
35748932373
-
Assessment of chronic lymphocytic leukemia and small lymphocytic lymphoma by absolyte lymphocyte counts in 2126 patients: 20 years of experience at the University of Texas MD Anderson Cancer Center
-
Tsimberidou AM, Wen S, O'Brien S, et al. Assessment of chronic lymphocytic leukemia and small lymphocytic lymphoma by absolyte lymphocyte counts in 2126 patients: 20 years of experience at the University of Texas MD Anderson Cancer Center. J Clin Oncol. 2007;25(29):4648-4656.
-
(2007)
J Clin Oncol
, vol.25
, Issue.29
, pp. 4648-4656
-
-
Tsimberidou, A.M.1
Wen, S.2
O'Brien, S.3
-
67
-
-
33947541773
-
Phase III trial of fludarabine plus cyclophosphamide compared with fludarabine for patients with previously untreated chronic lymphocytic leukemia: US Intergroup Trial E2997
-
Flinn IW, Neuberg DS, Grever MR, et al. Phase III trial of fludarabine plus cyclophosphamide compared with fludarabine for patients with previously untreated chronic lymphocytic leukemia: US Intergroup Trial E2997. J Clin Oncol. 2007;25(7):793-798.
-
(2007)
J Clin Oncol
, vol.25
, Issue.7
, pp. 793-798
-
-
Flinn, I.W.1
Neuberg, D.S.2
Grever, M.R.3
-
68
-
-
23044510136
-
Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia
-
Keating MJ, O'Brien S, Albitar M, et al. Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia. J Clin Oncol. 2005;23(18):4079-4088.
-
(2005)
J Clin Oncol
, vol.23
, Issue.18
, pp. 4079-4088
-
-
Keating, M.J.1
O'Brien, S.2
Albitar, M.3
-
69
-
-
0027505303
-
Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-B-D-arabinosyl-2-fluoroadenine
-
Robertson LE, Chubb S, Meyn RE, et al. Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-B-D-arabinosyl-2-fluoroadenine. Blood. 1993;81(1):143-150.
-
(1993)
Blood
, vol.81
, Issue.1
, pp. 143-150
-
-
Robertson, L.E.1
Chubb, S.2
Meyn, R.E.3
-
70
-
-
0034669944
-
Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria
-
Genini D, Adachi S, Chao Q, et al. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria. Blood. 2000;96(10):3537-3543.
-
(2000)
Blood
, vol.96
, Issue.10
, pp. 3537-3543
-
-
Genini, D.1
Adachi, S.2
Chao, Q.3
-
71
-
-
0026347961
-
2-Chlorodeoxyadenosine treatment of refractory chronic lymphocytic leukemia
-
Saven A, Carrera CJ, Carson DA, Beutler E, Piro LD. 2- Chlorodeoxyadenosine treatment of refractory chronic lymphocytic leukemia. Leuk Lymphoma. 1991;5[suppl]:133-138.
-
(1991)
Leuk Lymphoma
, vol.5
, Issue.SUPPL.
, pp. 133-138
-
-
Saven, A.1
Carrera, C.J.2
Carson, D.A.3
Beutler, E.4
Piro, L.D.5
-
72
-
-
16044374260
-
Intermittent 2-hour intravenous infusions of 2-chlorodeoxyadenosine in the treatment of 100 patients with refractory or previously untreated B-cell chronic lymphocytic leukemia
-
Robak T, Blasinska-Morawiec M, Krykowski E, et al. Intermittent 2-hour intravenous infusions of 2-chlorodeoxyadenosine in the treatment of 100 patients with refractory or previously untreated B-cell chronic lymphocytic leukemia. Leuk Lymphoma. 1996;22(5):509-522.
-
(1996)
Leuk Lymphoma
, vol.22
, Issue.5
, pp. 509-522
-
-
Robak, T.1
Blasinska-Morawiec, M.2
Krykowski, E.3
-
73
-
-
0035054979
-
Cladribine in combination with mitoxantrone and cyclophosphamide (CMC) in the treatment of heavily pre-treated patients with advanced indolent lymphoid malignancies
-
Robak T, Góra-Tybor J, Lech-Marańda E, Bloń ski JZ, Kasznicki M. Cladribine in combination with mitoxantrone and cyclophosphamide (CMC) in the treatment of heavily pre-treated patients with advanced indolent lymphoid malignancies. Eur J Haematol. 2001;66(3):188-194.
-
(2001)
Eur J Haematol
, vol.66
, Issue.3
, pp. 188-194
-
-
Robak, T.1
Góra-Tybor, J.2
Lech-Marańda, E.3
Bloński, J.Z.4
Kasznicki, M.5
-
74
-
-
0034063889
-
Cladribine with or without prednisone in the treatment of previously treated and untreated B-cell chronic lymphocytic leukaemia: Updated results of the multicentre study of 378 patients
-
Robak T, Blonski JZ, Kasznicki M, et al. Cladribine with or without prednisone in the treatment of previously treated and untreated B-cell chronic lymphocytic leukaemia: updated results of the multicentre study of 378 patients. Br J Haematol. 2000;108(2):357-368.
-
(2000)
Br J Haematol
, vol.108
, Issue.2
, pp. 357-368
-
-
Robak, T.1
Blonski, J.Z.2
Kasznicki, M.3
-
75
-
-
0028913580
-
Cladribine in the treatment of relapsed or refractory chronic lymphocytic leukemia
-
Tallman MS, Hakimian D, Zanzig C, et al. Cladribine in the treatment of relapsed or refractory chronic lymphocytic leukemia. J Clin Oncol. 1995;13(4):983-988.
-
(1995)
J Clin Oncol
, vol.13
, Issue.4
, pp. 983-988
-
-
Tallman, M.S.1
Hakimian, D.2
Zanzig, C.3
-
76
-
-
0030018146
-
Long-term survival following cladribine (2-chlorodeoxyadenosine) therapy in previously treated patients with chronic lymphocytic leukemia
-
Juliusson G, Liliemark J. Long-term survival following cladribine (2-chlorodeoxyadenosine) therapy in previously treated patients with chronic lymphocytic leukemia. Ann Oncol. 1996;7(4):373-379.
-
(1996)
Ann Oncol
, vol.7
, Issue.4
, pp. 373-379
-
-
Juliusson, G.1
Liliemark, J.2
-
77
-
-
0037214931
-
Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia
-
DOI 10.1002/cncr.11000
-
Montillo M, Tedeschi A, O'Brien S, et al. Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia. Cancer. 2003;97(1):114-120. (Pubitemid 36033870)
-
(2003)
Cancer
, vol.97
, Issue.1
, pp. 114-120
-
-
Montillo, M.1
Tedeschi, A.2
O'Brien, S.3
Di Raimondo, F.4
Lerner, S.5
Ferrajoli, A.6
Morra, E.7
Keating, M.J.8
-
78
-
-
0036179221
-
Oral cladribine for B-cell chronic lymphocytic leukemia: Report of a phase II trial with a 3-d, 3-weekly schedule in untreated and pretreated patients, and a long-term follow-up of 126 previously untreated patients
-
Karlsson K, Stromberg M, Liliemark J, et al. Oral cladribine for B-cell chronic lymphocytic leukemia: report of a phase II trial with a 3-d, 3-weekly schedule in untreated and pretreated patients, and a long-term follow-up of 126 previously untreated patients. Br J Haematol. 2002;116(3):538-548.
-
(2002)
Br J Haematol
, vol.116
, Issue.3
, pp. 538-548
-
-
Karlsson, K.1
Stromberg, M.2
Liliemark, J.3
-
79
-
-
8044250299
-
2-Chlorodeoxyadenosine in the treatment of relapsed/refractory chronic lymphoproliferative disorders
-
Rondelli D, Lauria F, Zinzani PL, et al. 2-Chlorodeoxyadenosine in the treatment of relapsed/refractory chronic lymphoproliferative disorders. Eur J Haematol. 1997;58(1):46-50.
-
(1997)
Eur J Haematol
, vol.58
, Issue.1
, pp. 46-50
-
-
Rondelli, D.1
Lauria, F.2
Zinzani, P.L.3
-
80
-
-
0023758320
-
2-Chlorodeoxyadenosine: An effective new agent for the treatment of chronic lymphocytic leukemia
-
Piro LD, Carrera CJ, Beutler E, Carson DA. 2-Chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukemia. Blood. 1988;72(3):1069-1073.
-
(1988)
Blood
, vol.72
, Issue.3
, pp. 1069-1073
-
-
Piro, L.D.1
Carrera, C.J.2
Beutler, E.3
Carson, D.A.4
-
81
-
-
0028265320
-
Retreatment of chronic lymphocytic leukemia with 2-chlorodeoxyadenosine (CdA) at relapse following CdA-induced remission: No acquired resistance
-
Juliusson G, Liliemark J. Retreatment of chronic lymphocytic leukemia with 2-chlorodeoxyadenosine (CdA) at relapse following CdA-induced remission: no acquired resistance. Leuk Lymphoma. 1994;13(1):75-80.
-
(1994)
Leuk Lymphoma
, vol.13
, Issue.1
, pp. 75-80
-
-
Juliusson, G.1
Liliemark, J.2
-
82
-
-
0036660210
-
Re-treatment with cladribine-based regimens in relapsed patients with B-cell chronic lymphocytic leukemia: Efficacy and toxicity in comparison with previous treatment
-
Robak T, Bonski JZ, Kasznicki M, et al. Re-treatment with cladribine-based regimens in relapsed patients with B-cell chronic lymphocytic leukemia: efficacy and toxicity in comparison with previous treatment. Eur J Haematol. 2002;69(1):27-36.
-
(2002)
Eur J Haematol
, vol.69
, Issue.1
, pp. 27-36
-
-
Robak, T.1
Bonski, J.Z.2
Kasznicki, M.3
-
83
-
-
0028945716
-
2-Chlorodeoxyadenosine activity in patients with untreated chronic lymphocytic leukemia
-
Saven A, Lemon RH, Kosty M, Beutler E, Piro LD. 2-Chlorodeoxyadenosine activity in patients with untreated chronic lymphocytic leukemia. J Clin Oncol. 1995;13(3):570-574.
-
(1995)
J Clin Oncol
, vol.13
, Issue.3
, pp. 570-574
-
-
Saven, A.1
Lemon, R.H.2
Kosty, M.3
Beutler, E.4
Piro, L.D.5
-
84
-
-
0344783802
-
The effect of 2-h infusion of 2-chlorodeoxyadenosine (cladribine) with prednisone in previously untreated B-cell chronic lymphocytic leukemia
-
Robak T, Blasinska-Morawiec M, Blonski JZ, et al. The effect of 2-h infusion of 2-chlorodeoxyadenosine (cladribine) with prednisone in previously untreated B-cell chronic lymphocytic leukemia. Eur J Cancer. 1997;33(14):2347-2351.
-
(1997)
Eur J Cancer
, vol.33
, Issue.14
, pp. 2347-2351
-
-
Robak, T.1
Blasinska-Morawiec, M.2
Blonski, J.Z.3
-
85
-
-
72149085331
-
Cladribine (CdA) gives longer response duration than fludarabine (F) and high-dose intermittent chlorambucil (Chl) as first-line treatment of symptomatic chronic lymphocytic leukemia (CLL): First results from the International Randomized Phase III Trial
-
Karlsson K, Stromberg M, Jonsson V, Mulligan SP, Liliemark J, Juliusson G. Cladribine (CdA) gives longer response duration than fludarabine (F) and high-dose intermittent chlorambucil (Chl) as first-line treatment of symptomatic chronic lymphocytic leukemia (CLL): first results from the International Randomized Phase III Trial. Blood [ASH Annual Meeting Abstracts]. 2007;110:630.
-
(2007)
Blood [ASH Annual Meeting Abstracts]
, vol.110
, pp. 630
-
-
Karlsson, K.1
Stromberg, M.2
Jonsson, V.3
Mulligan, S.P.4
Liliemark, J.5
Juliusson, G.6
-
86
-
-
0034667537
-
Cladribine with prednisone versus chlorambucil with prednisone as first-line therapy in chronic lymphocytic leukemia: A report of a prospective, randomized, multicenter trial
-
Robak T, Blonski JZ, Kasznicki M, et al. Cladribine with prednisone versus chlorambucil with prednisone as first-line therapy in chronic lymphocytic leukemia: a report of a prospective, randomized, multicenter trial. Blood. 2000;96(8):2723-2729.
-
(2000)
Blood
, vol.96
, Issue.8
, pp. 2723-2729
-
-
Robak, T.1
Blonski, J.Z.2
Kasznicki, M.3
-
87
-
-
33745942111
-
Cladribine alone and in combination with cyclophosphamide or cyclophosphamide plus mitoxantrone in the treatment of progressive chronic lymphocytic leukemia: Report of a prospective, multicenter, randomized trial of the Polish Adult Leukemia Group (PALG CLL2)
-
Robak T, Blonski JZ, Gora-Tybor J, et al. Cladribine alone and in combination with cyclophosphamide or cyclophosphamide plus mitoxantrone in the treatment of progressive chronic lymphocytic leukemia: report of a prospective, multicenter, randomized trial of the Polish Adult Leukemia Group (PALG CLL2). Blood. 2006;108(2):473-479.
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 473-479
-
-
Robak, T.1
Blonski, J.Z.2
Gora-Tybor, J.3
-
88
-
-
77951628255
-
Comparison of cladribine plus cyclophosphamide with fludarabine plus cyclophosphamide as first-line therapy for chronic lymphocytic leukemia: A Phase III randomized study by the Polish Adult Leukemia Group (PALG-CLL3 Study)
-
Robak T, Jamroziak K, Tybor J, et al. Comparison of cladribine plus cyclophosphamide with fludarabine plus cyclophosphamide as first-line therapy for chronic lymphocytic leukemia: a Phase III randomized study by the Polish Adult Leukemia Group (PALG-CLL3 Study). J Clin Oncol. 2010;28(11):1863-1869.
-
(2010)
J Clin Oncol
, vol.28
, Issue.11
, pp. 1863-1869
-
-
Robak, T.1
Jamroziak, K.2
Tybor, J.3
-
89
-
-
0028231835
-
Phase I study of combined 2-chlorodeoxyadenosine and chlorambucil in chronic lymphoid leukemia and low-grade lymphoma
-
Tefferi A, Witzig TE, Reid JM, Li CY, Ames MM. Phase I study of combined 2-chlorodeoxyadenosine and chlorambucil in chronic lymphoid leukemia and low-grade lymphoma. J Clin Oncol. 1994;12(3):569-574.
-
(1994)
J Clin Oncol
, vol.12
, Issue.3
, pp. 569-574
-
-
Tefferi, A.1
Witzig, T.E.2
Reid, J.M.3
Li, C.Y.4
Ames, M.M.5
-
90
-
-
0026675806
-
Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine
-
Juliusson G, Elmhorn-Rosenberg A, Liliemark J. Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine. N Engl J Med. 1992;327(15):1056-1061.
-
(1992)
N Engl J Med
, vol.327
, Issue.15
, pp. 1056-1061
-
-
Juliusson, G.1
Elmhorn-Rosenberg, A.2
Liliemark, J.3
-
91
-
-
0028096165
-
Lack of effect of 2-chlorodeoxyadenosine therapy in patients with chronic lymphocytic leukemia refractory to fludarabine therapy
-
O'Brien S, Kantarjian H, Estey E, et al. Lack of effect of 2-chlorodeoxyadenosine therapy in patients with chronic lymphocytic leukemia refractory to fludarabine therapy. N Engl J Med. 1994;330(5):319-322.
-
(1994)
N Engl J Med
, vol.330
, Issue.5
, pp. 319-322
-
-
O'Brien, S.1
Kantarjian, H.2
Estey, E.3
-
92
-
-
34447530283
-
Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): A randomized controlled trial
-
Catovsky D, Richards S, Matutes E, et al. Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomized controlled trial. Lancet. 2007;370(9583):230-239.
-
(2007)
Lancet
, vol.370
, Issue.9583
, pp. 230-239
-
-
Catovsky, D.1
Richards, S.2
Matutes, E.3
-
93
-
-
31544434508
-
Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia
-
Eichhorst BF, Busch R, Hopfinger G, et al. Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia. Blood. 2006;107(3):885-891.
-
(2006)
Blood
, vol.107
, Issue.3
, pp. 885-891
-
-
Eichhorst, B.F.1
Busch, R.2
Hopfinger, G.3
-
94
-
-
58949092546
-
Activity of cladribine combined with cyclophosphamide in frontline therapy for chronic lymphocytic leukemia 2ith 17p13.1/TP53 deletion
-
Robak T, Blonski JZ, Wawrzyniak E, et al. Activity of cladribine combined with cyclophosphamide in frontline therapy for chronic lymphocytic leukemia 2ith 17p13.1/TP53 deletion. Cancer. 2009;115(1):94-100.
-
(2009)
Cancer
, vol.115
, Issue.1
, pp. 94-100
-
-
Robak, T.1
Blonski, J.Z.2
Wawrzyniak, E.3
-
95
-
-
0028219970
-
2-Chlorodeoxyadenosine: A newer purine analog active in the treatment of indolent lymphoid malignancies
-
Saven A, Piro L. 2-Chlorodeoxyadenosine: a newer purine analog active in the treatment of indolent lymphoid malignancies. Ann Intern Med. 1994;120(9):784-791.
-
(1994)
Ann Intern Med
, vol.120
, Issue.9
, pp. 784-791
-
-
Saven, A.1
Piro, L.2
-
96
-
-
77958193425
-
Improved survival in acute myeloid leukaemia patients aged over 40 given cladribine in combination with standard remission induction (DA 3+7) and consolidation treatment (HD AraC): Seven year follow-up of prospective, cooperative PALG study
-
Holowiecki J, Grosicki S, Hellmann A, et al. Improved survival in acute myeloid leukaemia patients aged over 40 given cladribine in combination with standard remission induction (DA 3+7) and consolidation treatment (HD AraC): seven year follow-up of prospective, cooperative PALG study. Blood [ASH Annual Meeting Abstracts]. 2006;108:2003.
-
(2006)
Blood [ASH Annual Meeting Abstracts]
, vol.108
, pp. 2003
-
-
Holowiecki, J.1
Grosicki, S.2
Hellmann, A.3
-
97
-
-
77958164047
-
Cladribine in combination with standard daunorubicine and cytarabine (DAC) as a remission induction treatment improves the overall survival in untreated adults with AML aged < 60 y contrary to combination including fludarabine (DAF). A multicenter, randomized, phase III PALG AML 1/2004 DAC/DAF/DA study in 673 patients: A final update
-
Holowiecki J, Grosicki S, Kyrcz-Krzemien S, et al. Cladribine in combination with standard daunorubicine and cytarabine (DAC) as a remission induction treatment improves the overall survival in untreated adults with AML aged < 60 y contrary to combination including fludarabine (DAF). A multicenter, randomized, phase III PALG AML 1/2004 DAC/DAF/DA study in 673 patients: a final update. Blood [ASH Annual Meeting Abstracts]. 2009;114:2055.
-
(2009)
Blood [ASH Annual Meeting Abstracts]
, vol.114
, pp. 2055
-
-
Holowiecki, J.1
Grosicki, S.2
Kyrcz-Krzemien, S.3
-
98
-
-
0033564769
-
Cladribine activity in adult Langerhans-cell histiocytosis
-
Saven A, Burian C. Cladribine activity in adult Langerhans-cell histiocytosis. Blood. 1999;93(12):4125-4130.
-
(1999)
Blood
, vol.93
, Issue.12
, pp. 4125-4130
-
-
Saven, A.1
Burian, C.2
-
100
-
-
70449704424
-
How I treat hypereosinophilic syndromes
-
Klion AD. How I treat hypereosinophilic syndromes. Blood. 2009;114(18):3736-3741.
-
(2009)
Blood
, vol.114
, Issue.18
, pp. 3736-3741
-
-
Klion, A.D.1
-
101
-
-
12944268972
-
Long-term analysis of the palliative benefit of 2-chlorodeoxyadenosine for myelofibrosis with myeloid metaplasia
-
DOI 10.1111/j.1600-0609.2004.00370.x
-
Faoro LN, Tefferi A, Mesa RA. Long-term analysis of the palliative benefit of 2-chlorodeoxyadenosine for myelofibrosis with myeloid metaplasia. Eur J Haematol. 2005;74(2):117-120. (Pubitemid 40175314)
-
(2005)
European Journal of Haematology
, vol.74
, Issue.2
, pp. 117-120
-
-
Faoro, L.N.1
Tefferi, A.2
Mesa, R.A.3
-
102
-
-
0026723519
-
2-Chlorodeoxyadeonsine: An active agent in the treatment of cutaneous T-cell lymphoma
-
Saven A, Carrera CJ, Carson DA, Beutler E, Piro LD. 2- Chlorodeoxyadeonsine: an active agent in the treatment of cutaneous T-cell lymphoma. Blood. 1992;80(3):587-592.
-
(1992)
Blood
, vol.80
, Issue.3
, pp. 587-592
-
-
Saven, A.1
Carrera, C.J.2
Carson, D.A.3
Beutler, E.4
Piro, L.D.5
-
103
-
-
0031033390
-
Major activity of cladribine in patients with de novo B-cell prolymphocytic leukemia
-
Saven A, Lee T, Schlutz M, et al. Major activity of cladribine in patients with de novo B-cell prolymphocytic leukemia. J Clin Oncol. 1997;15(1):37-43.
-
(1997)
J Clin Oncol
, vol.15
, Issue.1
, pp. 37-43
-
-
Saven, A.1
Lee, T.2
Schlutz, M.3
-
104
-
-
43049167322
-
Cladribine in indolent non-Hodgkin's lymphoma
-
Sigal D, Saven A. Cladribine in indolent non-Hodgkin's lymphoma. Exp Rev Anticancer Ther. 2008;8(4):535-545.
-
(2008)
Exp Rev Anticancer Ther
, vol.8
, Issue.4
, pp. 535-545
-
-
Sigal, D.1
Saven, A.2
-
105
-
-
0028289425
-
2-Chlorodeoxyadenosine induces durable remissions and prolonged suppression of CD4+ lymphocyte counts in patients with hairy cell leukemia
-
Seymour JF, Kurzrock R, Freireich EJ, Estey EH. 2-Chlorodeoxyadenosine induces durable remissions and prolonged suppression of CD4+ lymphocyte counts in patients with hairy cell leukemia. Blood. 1994;83(10):2906-2911.
-
(1994)
Blood
, vol.83
, Issue.10
, pp. 2906-2911
-
-
Seymour, J.F.1
Kurzrock, R.2
Freireich, E.J.3
Estey, E.H.4
-
106
-
-
43449109584
-
Management of infectious complications in patients with chronic lymphocytic leukemia
-
Morrison VA. Management of infectious complications in patients with chronic lymphocytic leukemia. Hematology. 2007:332-338.
-
(2007)
Hematology
, pp. 332-338
-
-
Morrison, V.A.1
-
107
-
-
0027323550
-
Results of fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment
-
O'Brien S, Kantarjian H, Beran M, et al. Results of fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment. Blood. 1993;82(6):1695-1700.
-
(1993)
Blood
, vol.82
, Issue.6
, pp. 1695-1700
-
-
O'Brien, S.1
Kantarjian, H.2
Beran, M.3
-
108
-
-
0032943423
-
Myelodysplastic syndrome with monosomy 5 and/or 7 following therapy with 2-chloro-2′-deoxyadenosine
-
Van Den Neste E, Louviaux I, Michaux J, et al. Myelodysplastic syndrome with monosomy 5 and/or 7 following therapy with 2-chloro-2′- deoxyadenosine. Br J Haematol. 1999;105(1):268-270.
-
(1999)
Br J Haematol
, vol.105
, Issue.1
, pp. 268-270
-
-
Van Den Neste, E.1
Louviaux, I.2
Michaux, J.3
-
109
-
-
58249093949
-
Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenstrom macroglobulinemia treated with nucleoside analogs
-
Leleu X, Soumerai J, Roccaro A, et al. Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenstrom macroglobulinemia treated with nucleoside analogs. J Clin Oncol. 2009;27(2):250-255.
-
(2009)
J Clin Oncol
, vol.27
, Issue.2
, pp. 250-255
-
-
Leleu, X.1
Soumerai, J.2
Roccaro, A.3
-
110
-
-
9144241003
-
Second malignancies and Richter's syndrome in patients with chronic lymphocytic leukaemia treated with cladribine
-
DOI 10.1016/j.ejca.2003.09.031
-
Robak T, Blosnki JZ, Gora-Tybor J, et al. Second malignancies and Richter's syndrome in patients with chronic lymphocytic leukaemia treated with cladribine. Eur J Cancer. 2004;40(3):383-389. (Pubitemid 38121276)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.3
, pp. 383-389
-
-
Robak, T.1
Blonski, J.Z.2
Gora-Tybor, J.3
Kasznicki, M.4
Konopka, L.5
Ceglarek, B.6
Komarnicki, M.7
Lewandowski, K.8
Hellmann, A.9
Lewandowski, K.10
Moskwa, A.11
Dmoszynska, A.12
Sokolowska, B.13
Dwilewicz-Trojaczek, A.14
Tomaszewska, A.15
Sulek, K.16
Calbecka, M.17
-
111
-
-
0032812729
-
Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias
-
Cheson BD, Vena DA, Barrett J, Freidlin B. Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias. J Clin Oncol. 1999;17(8):2454-2460.
-
(1999)
J Clin Oncol
, vol.17
, Issue.8
, pp. 2454-2460
-
-
Cheson, B.D.1
Vena, D.A.2
Barrett, J.3
Freidlin, B.4
-
112
-
-
0031845696
-
Autoimmune haemolysis in patients with B-CLL treated with chlorodeoxyadenosine (CDA)
-
Chasty RC, Myint H, Oscier DG, et al. Autoimmune haemolysis in patients with B-CLL treated with chlorodeoxyadenosine (CDA). Leuk Lymphoma. 1998;29(3):391-398.
-
(1998)
Leuk Lymphoma
, vol.29
, Issue.3
, pp. 391-398
-
-
Chasty, R.C.1
Myint, H.2
Oscier, D.G.3
-
113
-
-
0034101766
-
Delayed onset of autoimmune hemolytic anemia complicating cladribine therapy for Waldenstrom macroglobulinemia
-
Tetreault S, Saven A. Delayed onset of autoimmune hemolytic anemia complicating cladribine therapy for Waldenstrom macroglobulinemia. Leuk Lymphoma. 2000;37(1):125-130.
-
(2000)
Leuk Lymphoma
, vol.37
, Issue.1
, pp. 125-130
-
-
Tetreault, S.1
Saven, A.2
-
114
-
-
77958188539
-
Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with cladribine
-
Blonski JZ, Robak T, Trelinski J, et al. Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with cladribine. Blood [ASH Annual Meeting Abstracts]. 2008;112:4179.
-
(2008)
Blood [ASH Annual Meeting Abstracts]
, vol.112
, pp. 4179
-
-
Blonski, J.Z.1
Robak, T.2
Trelinski, J.3
-
115
-
-
0030995274
-
Autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia treated with 2-chlorodeoxyadenosine (cladribine)
-
Robak T, Blasińska-Morawiec M, Krykowski E, Hellmann A, Konopka L. Autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia treated with 2-chlorodeoxyadenosine (cladribine). Eur J Haematol. 1997;58(2):109-113.
-
(1997)
Eur J Haematol
, vol.58
, Issue.2
, pp. 109-113
-
-
Robak, T.1
Blasińska-Morawiec, M.2
Krykowski, E.3
Hellmann, A.4
Konopka, L.5
-
116
-
-
0035047759
-
Pure red cell aplasia in patients with chronic lymphocytic leukemia treated with cladribine
-
Robak T, Kasznicki M, Bloń ski JZ, Dmoszyńska A, Skotnicki AB. Pure red cell aplasia in patients with chronic lymphocytic leukemia treated with cladribine. Br J Haematol. 2001;112(4):1083-1085.
-
(2001)
Br J Haematol
, vol.112
, Issue.4
, pp. 1083-1085
-
-
Robak, T.1
Kasznicki, M.2
Bloński, J.Z.3
Dmoszyńska, A.4
Skotnicki, A.B.5
-
117
-
-
0027999381
-
Neurotoxicity of purine analogs: A review
-
Cheson BD, Vena DA, Foss FM, Sorensen JM. Neurotoxicity of purine analogs: a review. J Clin Oncol. 1994;12(10):2216-2228.
-
(1994)
J Clin Oncol
, vol.12
, Issue.10
, pp. 2216-2228
-
-
Cheson, B.D.1
Vena, D.A.2
Foss, F.M.3
Sorensen, J.M.4
-
118
-
-
76149083915
-
A placebo-controlled trial of oral cladribine for relapsing multiple sclerosis
-
Giovannoni G, Comi G, Cook S, et al. A placebo-controlled trial of oral cladribine for relapsing multiple sclerosis. N Engl J Med. 2010;362(5):416-426.
-
(2010)
N Engl J Med
, vol.362
, Issue.5
, pp. 416-426
-
-
Giovannoni, G.1
Comi, G.2
Cook, S.3
-
119
-
-
0029874963
-
Fulminant 2-chlorodeoxyadenosine-related peripheral neuropathy in a patient with paraneoplastic neurological syndrome associated with lymphoma
-
Warzocha K, Krykowski E, Gora-Tybor J, Fronczak A, Robak T. Fulminant 2-chlorodeoxyadenosine-related peripheral neuropathy in a patient with paraneoplastic neurological syndrome associated with lymphoma. Leuk Lymphoma. 1996;21(3):343-346.
-
(1996)
Leuk Lymphoma
, vol.21
, Issue.3
, pp. 343-346
-
-
Warzocha, K.1
Krykowski, E.2
Gora-Tybor, J.3
Fronczak, A.4
Robak, T.5
-
120
-
-
0028102950
-
Therapeutic and neurotoxic effects of 2-chlorodeoxyadenosine in adults with acute myeloid leukemia
-
Vahdat L, Wong ET, Wile MJ, Rosenblum M, Foley KM, Warrell RP. Therapeutic and neurotoxic effects of 2-chlorodeoxyadenosine in adults with acute myeloid leukemia. Blood. 1994;84(10):3429-3434.
-
(1994)
Blood
, vol.84
, Issue.10
, pp. 3429-3434
-
-
Vahdat, L.1
Wong, E.T.2
Wile, M.J.3
Rosenblum, M.4
Foley, K.M.5
Warrell, R.P.6
-
121
-
-
68449096428
-
Efficacy of BSI-201, a poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor, in combination with gemcitabine/carboplatin (B/C) in patients with metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II trial
-
O'Shaughnessy J, Osborne C, Pippen J, et al. Efficacy of BSI-201, a poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor, in combination with gemcitabine/carboplatin (B/C) in patients with metastatic triple-negative breast cancer (TNBC): results of a randomized phase II trial. J Clin Oncol [ASCO Annual Meeting Abstract]. 2009;27:3.
-
(2009)
J Clin Oncol [ASCO Annual Meeting Abstract]
, vol.27
, pp. 3
-
-
O'Shaughnessy, J.1
Osborne, C.2
Pippen, J.3
-
122
-
-
40749085662
-
Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents
-
Leoni LM, Bailey B, Reifert J, et al. Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents. Clin Cancer Res. 2008;14(1):309-317.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.1
, pp. 309-317
-
-
Leoni, L.M.1
Bailey, B.2
Reifert, J.3
-
123
-
-
41349109244
-
Bendamustine plus rituximab versus CHOP plus rituximab in the first-line treatment of patients with indolent and mantle cell lymphomas: First interim results of a randomized phase III study of the StiL (Study Group Indolent Lymphomas, Germany)
-
Rummel MJ, von Gruenhagen U, Niederle N, et al. Bendamustine plus rituximab versus CHOP plus rituximab in the first-line treatment of patients with indolent and mantle cell lymphomas: first interim results of a randomized phase III study of the StiL (Study Group Indolent Lymphomas, Germany). Blood [ASH Annual Meeting Abstract]. 2007;110:385.
-
(2007)
Blood [ASH Annual Meeting Abstract]
, vol.110
, pp. 385
-
-
Rummel, M.J.1
Von Gruenhagen, U.2
Niederle, N.3
|