Fulminant 2-chlorodeoxyadenosine-related peripheral neuropathy in a patient with paraneoplastic neurological syndrome associated with lymphoma

Leukemia and Lymphoma

Volumn 21, Issue 3-4, 1996, Pages 343-346

  Warzocha, K ^a,b   Krykowski, E ^a   Gora Tybor J ^a   Fronczak, A ^a   Robak, T ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b CENTRE HOSPITALIER LYON SUD   (France)

Author keywords

2 chlorodeoxyadenosine; Lymphoma; Neuropathy; Paraneoplastic syndrome; Treatment

Indexed keywords

ACICLOVIR; ANTIBIOTIC AGENT; CLADRIBINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DOXORUBICIN; IMMUNOGLOBULIN; PREDNISONE; VINCRISTINE;

ADULT; ARTICLE; BONE MARROW SUPPRESSION; CASE REPORT; CLINICAL TRIAL; HERPES; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; LYMPHOMA; MALE; NEUROTOXICITY; PARANEOPLASTIC SYNDROME; PERIPHERAL NEUROPATHY; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SENSORIMOTOR NEUROPATHY;

EID: 0029874963     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199209067618     Document Type: Article

References (14)

1. Haberland, C., Cipriani, M., Kucuk, O., Sarpel, G., Ezdinli, E. Z. and Ro, J. O. (1987) Fulminant leukemic polyradiculoneuropathy in a case of B-cell prolymphocytic leukemia. Cancer, 60, 1454-1458.
2. Symonds, R. P., Hogg, R. B. and Bone, I. (1994) Paraneoplastic neurological syndromes associated with lymphomas. Leukemia & Lymphoma, 15, 487-490.
3. Juliusson, G. and Liliemark, J. (1992) Rapid recovery from cytopenia in hairy cell leukemia after treatment with 2-chloro-2′ deoxyadenosine (CdA): relation to opportunistic infections. Blood, 79, 888-894.
4. Krykowski, E., Warzocha, K. and Robak, T. (1995) 2-Chlorodeoxyadenosine in the treatment of patients with relapsed chronic lymphocytic leukemia. Archivum Immunologiae et Therapiae Experimentalis, (in press).
5. Saven, A. and Piro, L. D. (1994) 2-Chlorodeoxyadenosine: a newer purine analog active in the treatment of indolent lymphoid malignancies. Annals of Internal Medicine, 120, 784-791.
6. Cheson, D. D., Vena, D. A., Foss, F. M. and Sorensen, J. M. (1994) Neurotoxicity of purine analogs: a review. Journal of Clinical Oncology, 12, 2216-2228.
7. Kobayashi, K., Vogelzang, N. J., O'Brien, S. M., Schilsky, R. L., Vokes, E. E. and Ratain, M. J. (1994) A phase I study of intermittent infusion cladribine in patients with solid tumors. Cancer, 74, 168-173.
8. Spielberger, R. T., Larson, R. A., O'Brien, S. M., Williams, S. F. and Ratain, M. J. (1993) Phase I study of 2-chlorodeoxyadenosine (CdA) by 1 hour bolus infusion in hematologic malignancies. Proceedings of the American Society of Clinical Oncology, 12, 140 (abstract 359).
9. Vahdat, L., Wong, E. T., Wile, M. J., Rosenblum, M., Foley, K. M. and Warrell, R. P. (1994) Therapeutic and neurotoxic effects of 2-chlorodeoxyadenosine in adults with acute myeloid leukemia. Blood, 84, 3429-3434.
10. Kearns, C. M., Blakley, R. L., Santana, V. M. and Crom, W. R. (1994) Pharmacokinetics of cladribine (2-chlorodeoxyadenosine) in children with acute leukemia. Cancer Research, 54, 1235-1239.
11. Góra-Tybor, J. and Robak, T. (1993) Synergistic action of 2-chlorodeoxyadenosine and cyclophosphamide on murine leukemia L1210 and leukemia P388. Acta Haematologica Polonica, 24, 177-182.
12. Saven, A., Kawasaki, H., Carrera, C. J., Waltz, T., Copeland, B., Zyroff, J., Kosty, M., Carson, D. A., Beutler, E. and Piro, L. D. (1993) 2-Chlorodeoxyadenosine dose escalation in nonhematologic malignancies. Journal of Clinical Oncology, 11, 671-678.
13. Delannoy, A., Hanique, G. and Ferrant, A. (1993) 2-Chlorodeoxyadenosine for patients with B-cell chronic lymphocytic leukemia resistant to fludarabine. New England Journal of Medicine, 328, 812.
14. Beutler, E., Piro, L. D., Saven, A., Kay, A. C., McMillian, R. and Longmire, R. (1991) 2-Chlorodeoxyadenosine (2-CdA): a potent chemotherapeutic and immunosuppressive nucleoside. Leukemia & Lymphoma, 5, 1-8.