The mechanics of atherosclerotic plaque rupture by inclusion/matrix interfacial decohesion

Journal of Biomechanics

Volumn 43, Issue 14, 2010, Pages 2702-2708

  Nguyen, Chien M ^a   Levy, Alan J ^a  

^a Syracuse University   (United States)

Author keywords

Atherosclerosis; Elasticity; Inclusion problem; Interfacial debonding and decohesion; Plaque rupture

Indexed keywords

ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE RUPTURES; BOUSSINESQ; CIRCUMFERENTIAL STRESS; DE-COHESION; DYNAMIC STRESS; EQUILIBRIUM SOLUTIONS; EXTRACELLULAR MATRICES; FINITE ELEMENT ANALYSIS; INCLUSION PROBLEM; INTEGRIN RECEPTORS; INTERFACIAL DEBONDING; INTERFACIAL DECOHESION; LINEAR ELASTIC; MATRIX; NOMINAL LOADS; PLAQUE RUPTURE; RIGID SPHERICAL INCLUSION; RUPTURE PROCESS; SPHERICAL DOMAIN; STRUCTURAL INTERFACE; THROMBUS FORMATION;

DEBONDING; DISEASES; ELASTICITY; FINITE ELEMENT METHOD; UNLOADING;

INCLUSIONS;

INTEGRIN RECEPTOR;

ARTERY RUPTURE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CALCIFICATION; ELASTICITY; EQUILIBRIUM CONSTANT; EXTRACELLULAR MATRIX; PRIORITY JOURNAL; SPIKE; STRESS; THROMBOGENESIS;

ATHEROSCLEROSIS; BIOMECHANICS; ELASTIC TISSUE; ELASTICITY; HEMORHEOLOGY; HUMANS; MODELS, CARDIOVASCULAR; NONLINEAR DYNAMICS; PLAQUE, ATHEROSCLEROTIC; RUPTURE, SPONTANEOUS; STRESS, MECHANICAL;

EID: 77958153465     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2010.06.012     Document Type: Article

References (38)

1. Barber JR. Elasticity. Dordrecht; Boston 2002, Kluwer Academic Publishers. 2nd ed.
2. Bertoldi K., Bigoni D., Drugan W.J. Structural interfaces in linear elasticity. Part I: nonlocality and gradient approximations. Journal of the Mechanics and Physics of Solids 2007, 55:1-34.
3. Bigoni D., Movchan A.B. Statics and dynamics of structural interfaces in elasticity. International Journal of Solids and Structures 2002, 39:4843-4865.
4. Bluestein D, Alemu Y, Avrahami I, Gharib M, Dumont K, Ricotta JJ, Einav S. Influence of microcalcifications on vulnerable plaque mechanics using FSI modeling. Journal of Biomechanics 2008, 41(5):1111-1118.
5. Cheng GC, Loree HM, Kamm RD, Fishbein MC, Lee RT. Distribution of circumferential stress in ruptured and stable atherosclerotic lesions. A structural analysis with histopathological correlation. Circulation 1993, 87(4):1179-1187.
6. Davies MJ. The composition of coronary-artery plaques. New England Journal of Medicine 1997, 336(18):1312-1314.
7. Finet G, Ohayon J, Rioufol G. Biomechanical interaction between cap thickness, lipid core composition and blood pressure in vulnerable coronary plaque: impact on stability or instability. Coronary Artery Diseases 2004, 15(1):13-20.
8. Fritton SP, Weinbaum S. Fluid and solute transport in bone: flow-induced mechanotransduction. Annual Review of Fluid Mechanics 2009, 41:347-374.
9. Gijsen FJ, Wentzel JJ, Thury A, Lamers B, Schuurbiers JC, Serruys PW, van der Steen AF. A new imaging technique to study 3-D plaque and shear stress distribution in human coronary artery bifurcations in vivo. Journal of Biomechanics 2007, 40(11):2349-2357.
10. Green AE, Zerna W. Theoretical Elasticity 1954, Clarendon: Press, Oxford.
11. Han Y, Cowin SC, Schaffler MB, Weinbaum S. Mechanotransduction and strain amplification in osteocyte cell processes. Proceedings of the National Academy of Sciences 2004, 101(47):16689-16694.
12. Imoto K, Hiro T, Fujii T, Murashige A, Fukumoto Y, Hashimoto G, Okamura T, Yamada J, Mori K, Matsuzaki M. Longitudinal structural determinants of atherosclerotic plaque vulnerability: a computational analysis of stress distribution using vessel models and three-dimensional intravascular ultrasound imaging. Journal of American College Cardiology 2005, 46(8):1507-1515.
13. Kock SA, Nygaard JV, Eldrup N, Frund ET, Klaerke A, Paaske WP, Falk E, Yong Kim W. Mechanical stresses in carotid plaques using MRI-based fluid-structure interaction models. Journal of Biomechanics 2008, 41(8):1651-1658.
14. 1 integrins. Langmuir 2004, 20(6):2397-2404.
15. Kolodgie FD, Burke AP, Farb A, Gold HK, Yuan J, Narula J, Finn AV, Virmani R. The thin-cap fibroatheroma: a type of vulnerable plaque: the major precursor lesion to acute coronary syndromes. Current Opinion in Cardiology 2001, 16(5):285-292.
16. Kullo IJ, Edwards WD, Schwartz RS. Vulnerable plaque: pathobiology and clinical implications. Annals of Internal Medicine 1998, 129(12):1050-1060.
17. Lau J, Kent D, Tatsioni A, et al. Vulnerable Plaques. A Brief Review of the Concept and Proposed Approaches to Diagnosis and Treatment. Technology Assessment 2004, Agency for Healthcare Research and Quality, Rockville, MD.
18. Lee R, Loree H, Cheng G, Lieberman E, Jaramillo N, Schoen F. Computational structural analysis based on intravascular ultrasound imaging before in vitro angioplasty: prediction of plaque fracture locations. Journal of American College Cardiology 1993, 21(3):777-782.
19. Levy AJ. Debonding of elastic inclusions and inhomogeneities. Journal of the Mechanics and Physics of Solids 1991, 39(4):477-505.
20. Levy AJ. On the nucleation of cavities in planar elasticity. Philosophical Transactions: Mathematical, Physical and Engineering Sciences 1997, 355(1734):2417-2458. 1998; Errata. vol. 356, pp. 669-670.
21. Li L, Huang HH, Badilla CL, Fernandez JM. Mechanical unfolding intermediates observed by single-molecule force spectroscopy in a fibronectin type III module. Journal of Molecular Biology 2005, 345(4):817-826.
22. Li ZY, Howarth S, Trivedi RA, U-King-Im JM, Graves MJ, Brown A, Wang L, Gillard JH. Stress analysis of carotid plaque rupture based on in vivo high resolution MRI. Journal of Biomechanics 2006, 39(14):2611-2622.
23. Linke WA, Kulke M, Li H, Fujita-Becker S, Neagoe C, Manstein DJ, Gautel M, Fernandez JM. PEVK domain of titin: an entropic spring with actin-binding properties. Journal of Structural Biology 2002, 137(1-2):194-205.
24. Loree H, Kamm R, Stringfellow R, Lee R. Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels. Circulation Research 1992, 71(4):850-858.
25. Maehara A, Mintz GS, Bui AB, Walter OR, Castagna MT, Canos D, Pichard AD, Satler LF, Waksman R, Suddath WO, et al. Morphologic and angiographic features of coronary plaque rupture detected by intravascular ultrasound. Journal of American College Cardiology 2002, 40(5):904-910.
26. Ohayon J, Teppaz P, Finet G, Rioufol G. In-vivo prediction of human coronary plaque rupture location using intravascular ultrasound and the finite element method. Coronary Artery Diseases 2001, 12(8):655-663.
27. Richardson PD, Davies MJ, Born GVR. Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. The Lancet 1989, 334(8669):941-944.
28. Takagi J, Petre BM, Walz T, Springer TA. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell 2002, 110(5):599-611.
29. Tang D, Yang C, Mondal S, Liu F, Canton G, Hatsukami TS, Yuan C. A negative correlation between human carotid atherosclerotic plaque progression and plaque wall stress: in vivo MRI-based 2D/3D FSI models. Journal of Biomechanics 2008, 41(4):727-736.
30. Tang D, Yang C, Zheng J, Woodard PK, Saffitz JE, Petruccelli JD, Sicard GA, Yuan C. Local maximal stress hypothesis and computational plaque vulnerability index for atherosclerotic plaque assessment. Annals of Biomedical Engineering 2005, 33(12):1789-1801.
31. Tsuchida E, Togawa S, Nakahara I, Kodama M. Stresses in a thick plate containing an eccentric spherical cavity under uniaxial tension. Bulletin of the Japan Society of Mechanical Engineers 1976, 19(134):838-848.
32. Vengrenyuk Y, Cardoso L, Weinbaum S. Micro-CT based analysis of a new paradigm for vulnerable plaque rupture: cellular microcalcifications in fibrous caps. Molecular and Cellular Biomechanics 2008, 5(1):37-47.
33. Vengrenyuk Y, Carlier S, Xanthos S, Cardoso L, Ganatos P, Virmani R, Einav S, Gilchrist L, Weinbaum S. A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps. Proceedings of the National Academy of Sciences 2006, 103(40):14678-14683.
34. Virmani R, Burke AP, Kolodgie FD, Farb A. Pathology of the thin-cap fibroatheroma: a type of vulnerable plaque. Journal of Interventional Cardiology 2003, 16(3):267-272.
35. Wang Y, McNamara LM, Schaffler MB, Weinbaum S. A model for the role of integrins in flow induced mechanotransduction in osteocytes. Proceedings of the National Academy of Sciences 2007, 104(40):15941-15946.
36. Xie M, Levy AJ. Defect propagation at a circular interface. International Journal of Fracture 2007, 144:1-20.
37. Xu X, Needleman A. Void nucleation by inclusion debonding in a crystal matrix. Modeling and Simulation in Materials Science and Engineering 1993, 1(2):111-132.
38. You L, Weinbaum S, Cowin SC, Schaffler MB. Ultrastructure of the osteocyte process and its pericellular matrix. The Anatomical Record Part A 2004, 278A:505-513.