Hypothalamic versus neocortical control of sleep

Current Opinion in Pulmonary Medicine

Volumn 16, Issue 6, 2010, Pages 530-535

  Szymusiak, Ronald ^a,b  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenosine; cytokines; preoptic hypothalamus; sleep homeostasis; synaptic homeostasis

Indexed keywords

4 AMINOBUTYRIC ACID; ADENOSINE; CYTOKINE; GROWTH HORMONE RELEASING FACTOR; PROSTAGLANDIN D2; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ENERGY BALANCE; EVOKED RESPONSE; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HYPOTHALAMUS; NEOCORTEX; NERVE CELL PLASTICITY; NONHUMAN; PROTEIN EXPRESSION; REVIEW; SLEEP; SLOW WAVE SLEEP; SUPRACHIASMATIC NUCLEUS; WAKEFULNESS;

ANIMALS; ELECTROENCEPHALOGRAPHY; HOMEOSTASIS; HUMANS; HYPOTHALAMUS; MODELS, ANIMAL; NEOCORTEX; SLEEP; SLEEP, REM;

EID: 77958153169     PISSN: 10705287     EISSN: 15316971     Source Type: Journal    
DOI: 10.1097/MCP.0b013e32833eec92     Document Type: Review

References (64)

1. Moruzzi G, Magoun H. Brainstem reticular formation and activation of the EEG. Electroenceph Clin Neurophysiol 1949; 1:455-473.
2. Nauta WJH. Hypothalamic regulation of sleep in rats. An experimental study. J Neurophysiol 1946; 9:285-316.
3. McGinty D, Sterman MB. Sleep suppression after basal forebrain lesions in the cat. Science 1968; 160:1253-1255.
4. Sterman MB, Clemente CD. Forebrain inhibitory mechanisms: sleep patterns induced by basal forebrain stimulation in the behaving cat. Exp Neurol 1962; 6:103-117.
5. Villablanca JR. Counterpointing the functional role of the forebrain and the brainstem in the control of sleep-waking systems. J Sleep Res 2004; 13: 179-208.
6. Saper CB, Scammel T, Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature 2005; 437:1257-1263. (Pubitemid 41568665)
7. Szymusiak R, Gvilia I, McGinty D. Hypothalamic control of sleep. Sleep Med 2007; 8:291-301. (Pubitemid 46706353)
8. Espana RA, Scammell TE. Sleep neurobiology for the clinician. Sleep 2004; 27:811-820.
9. Jones BE. Basic mechanisms of sleep-wake states. In: Kryger MH, Roth T, Dement WC, editors. Principles and practice of sleep medicine. Philadelphia: Elsevier Saunders; 2005. pp. 136-153.
10. McCarley RW. Neurobiology of REM and NREM sleep. Sleep Med 2007; 8:302-330.
11. Szymusiak R, Alam N, Steininger TL, McGinty D. Sleep-waking discharge patterns of ventrolateral preoptic/anterior hypothalamic neurons in rats. Brain Res 1998; 803:178-188. (Pubitemid 28392144)
12. Suntsova N, Szymusiak R, Alam MN, et al. Sleep-waking discharge patterns of median preoptic nucleus neurons. J Physiol 2002; 543:665-677. (Pubitemid 35012218)
13. Sherin JE, Shiromani PJ, McCarley RW, Saper CB. Activation of ventrolateral preoptic neurons during sleep. Science 1996; 271:216-219. (Pubitemid 26033304)
14. Gong H, McGinty D, Guzman-Marin R, et al. Activation of c-Fos in GABAergic neurones in the preoptic area during sleep and in response to sleep deprivation. J Physiol 2004; 556:935-946. (Pubitemid 38660324)
15. Gaus SE, Strecker RE, Tate BA, et al. Ventrolateral preoptic nucleus contains sleep-active, galaninergic neurons in multiple mammalian species. Neuroscience 2002; 115:285-294.
16. Gvilia I, Xu F, McGinty D, Szymusiak R. Homeostatic regulation of sleep: a role for preoptic area neurons. J Neurosci 2006; 26:9426-9433. (Pubitemid 44396855)
17. Lu J, Greco MA, Shiromani P, Saper CB. Effect of lesions of the ventrolateral preoptic nucleus on NREM and REM sleep. J Neurosci 2000; 20:3830-3842. (Pubitemid 30266244)
18. John J, Kumar V. Effect of NMDA lesions of the medial preoptic neurons on sleep and other functions. Sleep 1998; 21:587-598. (Pubitemid 28440701)
19. Basheer R, Strecker RE, Thakkar MM, McCarley RW. Adenosine and sleep- wake regulation. Prog Neurobiol 2004; 73:379-396.
20. Porkka-Heiskanen T, Strecker RE, McCarley RW. Brain site specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study. Neuroscience 2000; 99:507-517. (Pubitemid 30612453)
21. Chamberlin NL, Arrigoni E, Chou TC, et al. Effects of adenosine on GABAergic synaptic inputs to identified ventrolateral preoptic neurons. Neuroscience 2003; 119:913-918. (Pubitemid 36776442)
22. Bjorness TE, Kelly C, Gao T, et al. Control and function of the homeostatic sleep response by adenosine A1 receptors. J Neurosci 2009; 29:1267-1276.
23. Morairty S, Rainnie D, McCarley RW, Greene RW. Disinhibition of ventrolateral preoptic area sleep-active neurons by adenosine: a new mechanism for sleep promotion. Neuroscience 2004; 123:451-457. (Pubitemid 38032921)
24. Scammell T, Gerashchenko D, Mochizuki T, et al. An adenosine A2A agonist increases sleep and induces Fos in ventrolateral preoptic area neurons. Neuroscience 2001; 107:653-663. (Pubitemid 33097501)
25. Obal F Jr, Krueger JM. Biochemical regulation of nonrapid-eye-movement sleep. Front Biosci 2003; 8:d520-d550.
26. Krueger JM, Rector D, Roy S, et al. Sleep as a fundamental property of neuronal assemblies. Nat Rev Neurosci 2008; 9:910-919.
27. Alam MN, McGinty D, Imeri L, et al. Effects of interleukin 1-beta on sleep- and wake-related preoptic/anterior hypothalamic neurons in unrestrained rats. Sleep 2001; 24:A59.
28. Baker FC, Shah S, Stewart D, et al. Interleukin 1b enhances nonrapid eye movement sleep and increases c-Fos protein expression in the median preoptic nucleus of the hypothalamus. Am J Physiol Regul Integr Comp Physiol 2005; 288:R998-R1005. (Pubitemid 40404176)
29. Brambilla M, Bianchi S,Mariotti M, et al. Interleukin-1b enhances nonrapid eye movement sleep when microinjected into the dorsal raphe nucleus and inhibits serotonergic neurons in vitro. Eur J Neurosci 2003; 18:1041-1049.
30. Brambill D, Franciosi S, Opp M, Imeri L. Interleukin-1 inhibits firing of serotonergic neurons in the dorsal raphe nucleus and enhances GABAergic inhibitory post synaptic potentials. Eur J Neurosci 2007; 26:1862-1869. (Pubitemid 47493185)
31. Scammell T, Gerashchenko D, Urade Y, et al. Actviation of ventrolateral preoptic neurons by the smonogen prostaglandin D2. Proc Natl Acad Sci U S A 1998; 95:7754-7759. (Pubitemid 28293326)
32. Peterfi Z, McGinty D, Sarai E, Szymusiak R. Growth hormone-releasing hormone activates sleep regulatory neurons of the rat preoptic hypothalamus. Am J Physiol 2010; 298:R147-R156.
33. Mistlberger RE. Circadian regulation of sleep in mammals: role of the suprachiasmatic nucleus. Brain Res Rev 2005; 49:429-454.
34. Zhou Q, Cheng M. Prokineticin 2 and circadian clock output. FEBS J 2005; 272:5703-5709. (Pubitemid 41689344)
35. Kramer A, Yang F, Snodgrass P, et al. Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling. Science 2001; 294:2511-2515. (Pubitemid 34027284)
36. Chou TC, Scammel T, Gooley J, et al. Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci 2003; 23:10691-10702. (Pubitemid 37485283)
37. Saint-Mleux B, Bayer L, Eggermann E, et al. Suprachiasmatic modulation of noradrenalin release in the ventrolateral preoptic nucleus. J Neurosci 2007; 27:6412-6416. (Pubitemid 46920362)
38. Borbely A, Acherman P. Sleep homeostasis and models of sleep regulation. J Biol Rhythms 1999; 14:557-568. (Pubitemid 30086864)
39. Tononi G, Cirelli C. Sleep function and synaptic homeostasis. Sleep Med Rev 2006; 10:49-62. (Pubitemid 43106851)
40. Rector D, Schei J, Van Dongen H, et al. Physiological markers of local sleep. Eur J Neurosci 2009; 29:1771-1778.
41. Huber R, Ghilardi M, Massimini M, Tononi G. Local sleep and learning. Nature 2004; 430:78-81. (Pubitemid 38915227)
42. Huber R, Ghilardi M, Massimini M, et al. Arm immobilization causes cortical plastic changes and locally decreases sleep slow-wave activity. Nat Neurosci 2006; 9:1169-1176. (Pubitemid 44306311)
43. Vyazovskiy V, Borbely A, Tobler I. Unilateral vibrissae stimulation during waking induces interhemispheric EEG asymmetry during subsequent sleep in the rat. J Sleep Res 2000; 9:367-371. (Pubitemid 32050050)
44. Hanlon E, Faraguna U, Vyazovskiy V, et al. Effects of skilled training on sleepslow-wave activity and cortical gene expression in the rat. Sleep 2009; 32:719-729.
45. Morin L, Meyer-Bernstein EL. The ascending serotonergic system in the hamster: comparison with projections of the dorsal and median raphe nuclei. Neuroscience 1999; 91:81-105. (Pubitemid 29170450)
46. Halassa M, Florian C, Fellin T, et al. Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss. Neuron 2009; 61:213-219.
47. Szentirmai E, Yasuda T, Taishi P, et al. Growth hormone-releasing hormone: cerebral cortical sleep-related EEG actions and expression. Am J Physiol 2007; 293:R922-R930. (Pubitemid 47205080)
48. Cirelli C, Tononi G. Differential expression of plasticity-related genes in waking and sleep and their regulation by the noradrenergic system. J Neurosci 2000; 20:9187-9194. (Pubitemid 32042921)
49. Huber R, Tononi G, Cirelli C. Exploratory behavior, cortical BDNF expression and sleep homeostasis. Sleep 2007; 30:129-139. (Pubitemid 46247838)
50. Faraguna U, Nelson A, Vyazovskiy V, et al. Unilateral cortical spreading depression affects sleep need and induces molecular and electrophysiological signs of synaptic potentiation in vivo. Cereb Cortex 2010 [Epub ahead of print].
51. Faraguna U, Vyazovskiy V, Nelson A, et al. A causal role for brain-derived neurotrophic factor in the homeostatic regulation of sleep. J Neurosci 2008; 28:4088-4095.
52. Vyazovskiy V, Cirelli C, Pfister-Genskow M, et al. Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression during sleep. Nat Neurosci 2008; 11:2000-2008. (Pubitemid 351170495)
53. Vyazovskiy V, Olcese U, Lazimy Y, et al. Cortical firing and sleep homeostasis. Neuron 2009; 63:865-878.
54. Liu Z-W, Faraguna U, Cirelli C, et al. Direct evidence for wake-related increases and sleep-related decreases in synaptic strength in rodent cortex. J Neurosci 2010; 30:8671-8675.
55. Liu Z, Gao X. Adenosine inhibits activity of hypocretin/orexin neurons by the A1 receptor in the lateral hypothalamus: a possible sleep-promoting effect. J Neurophysiol 2007; 97:837-848. (Pubitemid 46143399)
56. Churchill L, Rector D, Yasusda K, et al. Tumor necrosis factor a: activity dependent expression and promotiong of cortical column sleep in rats. Neuroscience 2008; 156:71-80.
57. Hallett H, Churchill L, Taishi P, et al. Whisker stimulation increases expression of nerve growth factor- and interleukin-1-beta immunoreactivity in the rat somatosensory cortex. Brain Res 2010; 1333:48-56.
58. Yasuda T, Yoshida H, Garcia-Garcia F, et al. Interleukin-1beta has a role in cerebral cortical state-dependent electroencephalographic slow-wave activity. Sleep 2005; 28:177-184. (Pubitemid 40362643)
59. Yoshida H, Peterfi Z, Garcia-Garcia F, et al. State-specific asymmetries in EEG slow wave activity induced by local application of TNFa. Brain Res 2004; 1009:129-136. (Pubitemid 38553855)
60. Taishi P, Churchill L, Wang M, et al. TNFa siRNA reduces brain TNF and EEG delta wave activity in rats. Brain Res 2007; 1156:125-132. (Pubitemid 46920522)
61. Liao F, Taishi P, Churchill L, et al. Localized suppression of cortical growth hormone-releasing hormone receptors state specifically attenuates electroencephalographic delta waves. J Neurosci 2010; 30:151-159.
62. Santello M, Volterra A. Synaptic modulation by astrocytes via Ca2+dependent glutamate release. Neuroscience 2009; 158:253-259.
63. Yasusda K, Churchill L, Yasuda T, et al. Unilateral cortical application of interleukin-1b induces asymmertry in fos, IL1b and nerve growth factor immunoreactivity: implications for sleep regulation. Brain Res 2007; 1131: 44-59. (Pubitemid 46075115)
64. Gerashchenko D, Okano Y, Urade Y, et al. Strong rebound of wakefulness follows prostaglandin D2 or adenosine A2A receptor agonist-induced sleep. J Sleep Res 2000; 9:81-87. (Pubitemid 30195297)