Enhancing trophic support of mesenchymal stem cells by ex vivo treatment with trophic factors

Journal of the Neurological Sciences

Volumn 298, Issue 1-2, 2010, Pages 28-34

  Choi, Yun Jung ^a   Li, Wen Yu ^b   Moon, Gyeong Joon ^c   Lee, Phil Hyu ^d   Ahn, Young Hwan ^a   Lee, Gwang ^a   Bang, Oh Young ^c  

^a Ajou University School of Medicine   (South Korea)

^b ZHEJIANG UNIVERSITY   (China)

^c Sungkyunkwan University   (South Korea)

^d Yonsei University College of Medicine   (South Korea)

Author keywords

Bone marrow; Mesenchymal stem cells; Stem cells; Stroke ischemic; Trophic factors

Indexed keywords

BRAIN DERIVED GROWTH FACTOR; CELL SURFACE MARKER; NEUROTROPHIC FACTOR; SCATTER FACTOR; VASCULOTROPIN;

ANIMAL MODEL; ARTICLE; AUTOCRINE EFFECT; BRAIN ISCHEMIA; CELL CULTURE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ANIMALS; BRAIN ISCHEMIA; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL SEPARATION; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPATOCYTE GROWTH FACTOR; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; STROKE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77958152038     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2010.09.003     Document Type: Article

References (35)

1. J. Chen, Y. Li, L. Wang, Z. Zhang, D. Lu, and M. Lu Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats Stroke 32 2001 1005 1011
2. Y. Li, J. Chen, X.G. Chen, L. Wang, S.C. Gautam, and Y.X. Xu Human marrow stromal cell therapy for stroke in rat: neurotrophins and functional recovery Neurology 59 2002 514 523
3. L.R. Zhao, W.M. Duan, M. Reyes, C.D. Keene, C.M. Verfaillie, and W.C. Low Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats Exp Neurol 174 2002 11 20
4. O.Y. Bang, J.S. Lee, P.H. Lee, and G. Lee Autologous mesenchymal stem cell transplantation in stroke patients Ann Neurol 57 2005 874 882
5. M.K. Majumdar, M.A. Thiede, S.E. Haynesworth, S.P. Bruder, and S.L. Gerson Human marrow-derived mesenchymal stem cells (MSCs) express hematopoietic cytokines and support long-term hematopoiesis when differentiated toward stromal and osteogenic lineages J Hematother Stem Cell Res 9 2000 841 848
6. S.P. Dormady, O. Bashayan, R. Dougherty, X.M. Zhang, and R.S. Basch Immortalized multipotential mesenchymal cells and the hematopoietic microenvironment J Hematother Stem Cell Res 10 2001 125 140
7. G. Wieczorek, C. Steinhoff, R. Schulz, M. Scheller, M. Vingron, and H.H. Ropers Gene expression profile of mouse bone marrow stromal cells determined by CDNA microarray analysis Cell Tissue Res 311 2003 227 237
8. X. Chen, Y. Li, L. Wang, M. Katakowski, L. Zhang, and J. Chen Ischemic rat brain extracts induce human marrow stromal cell growth factor production Neuropathology 22 2002 275 279
9. M. Gnecchi, H. He, N. Noiseux, O.D. Liang, L. Zhang, and F. Morello Evidence supporting paracrine hypothesis for AKT-modified mesenchymal stem cell-mediated cardiac protection and functional improvement FASEB J 20 2006 661 669
10. X. Chen, M. Katakowski, Y. Li, D. Lu, L. Wang, and L. Zhang Human bone marrow stromal cell cultures conditioned by traumatic brain tissue extracts: growth factor production J Neurosci Res 69 2002 687 691
11. D. Lu, A. Mahmood, L. Wang, Y. Li, M. Lu, and M. Chopp Adult bone marrow stromal cells administered intravenously to rats after traumatic brain injury migrate into brain and improve neurological outcome NeuroReport 12 2001 559 563
12. W.Y. Li, Y.J. Choi, P.H. Lee, K. Huh, Y.M. Kang, and H.S. Kim Mesenchymal stem cells for ischemic stroke: changes in effects after ex vivo culturing Cell Transplant 17 2008 1045 1059
13. S.I. Savitz, D.M. Rosenbaum, J.H. Dinsmore, L.R. Wechsler, and L.R. Caplan Cell transplantation for stroke Ann Neurol 52 2002 266 275
14. W.R. Schabitz, T. Steigleder, C.M. Cooper-Kuhn, S. Schwab, C. Sommer, and A. Schneider Intravenous brain-derived neurotrophic factor enhances poststroke sensorimotor recovery and stimulates neurogenesis Stroke 38 2007 2165 2172
15. Y.Q. Wang, X. Guo, M.H. Qiu, X.Y. Feng, and F.Y. Sun VEGF overexpression enhances striatal neurogenesis in brain of adult rat after a transient middle cerebral artery occlusion J Neurosci Res 85 2007 73 82
16. K. Kurozumi, K. Nakamura, T. Tamiya, Y. Kawano, K. Ishii, and M. Kobune Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model Mol Ther 11 2005 96 104
17. R.J. Lichtenwalner, and J.M. Parent Adult neurogenesis and the ischemic forebrain J Cereb Blood Flow Metab 26 2006 1 20
18. Y. Horita, O. Honmou, K. Harada, K. Houkin, H. Hamada, and J.D. Kocsis Intravenous administration of glial cell line-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat J Neurosci Res 84 2006 1495 1504
19. M.Z. Zhao, N. Nonoguchi, N. Ikeda, T. Watanabe, D. Furutama, and D. Miyazawa Novel therapeutic strategy for stroke in rats by bone marrow stromal cells and ex vivo HGF gene transfer with HSV-1 vector J Cereb Blood Flow Metab 26 2006 1176 1188
20. T. Nomura, O. Honmou, K. Harada, K. Houkin, H. Hamada, and J.D. Kocsis I.V. Infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat Neuroscience 136 2005 161 169
21. R. Matsumoto, T. Omura, M. Yoshiyama, T. Hayashi, S. Inamoto, and K.R. Koh Vascular endothelial growth factor-expressing mesenchymal stem cell transplantation for the treatment of acute myocardial infarction Arterioscler Thromb Vasc Biol 25 2005 1168 1173
22. H. Liu, O. Honmou, K. Harada, K. Nakamura, K. Houkin, and H. Hamada Neuroprotection by PLGF gene-modified human mesenchymal stem cells after cerebral ischaemia Brain 129 2006 2734 2745
23. H. Chen, M. Chopp, Z.G. Zhang, and J.H. Garcia The effect of hypothermia on transient middle cerebral artery occlusion in the rat J Cereb Blood Flow Metab 12 1992 621 628
24. M.K. Majumdar, M.A. Thiede, J.D. Mosca, M. Moorman, and S.L. Gerson Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells J Cell Physiol 176 1998 57 66
25. A.E. Lang, S. Gill, N.K. Patel, A. Lozano, J.G. Nutt, and R. Penn Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease Ann Neurol 59 2006 459 466
26. D.C. Young, and J.D. Griffin Autocrine secretion of GM-CSF in acute myeloblastic leukemia Blood 68 1986 1178 1181
27. A. Janowska-Wieczorek, M. Majka, J. Ratajczak, and M.Z. Ratajczak Autocrine/paracrine mechanisms in human hematopoiesis Stem Cells 19 2001 99 107
28. M. Majka, A. Janowska-Wieczorek, J. Ratajczak, K. Ehrenman, Z. Pietrzkowski, and M.A. Kowalska Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner Blood 97 2001 3075 3085
29. Chen TS, Lai RC, Lee MM, Choo AB, Lee CN, Lim SK: Mesenchymal stem cell secretes microparticles enriched in pre-micrornas. Nucleic Acids Res;38:215-224.
30. M.A. Laurenzi, T. Beccari, L. Stenke, M. Sjolinder, S. Stinchi, and J.A. Lindgren Expression of MRNA encoding neurotrophins and neurotrophin receptors in human granulocytes and bone marrow cells-enhanced neurotrophin-4 expression induced by LTB4 J Leukoc Biol 64 1998 228 234
31. F. Hefti Neurotrophic factor therapy for nervous system degenerative diseases J Neurobiol 25 1994 1418 1435
32. L. Olson, L. Backman, T. Ebendal, M. Eriksdotter-Jonhagen, B. Hoffer, and C. Humpel Role of growth factors in degeneration and regeneration in the central nervous system; clinical experiences with NGF in Parkinson's and Alzheimer's diseases J Neurol 242 1994 S12 S15
33. S.M. Klein, S. Behrstock, J. McHugh, K. Hoffmann, K. Wallace, and M. Suzuki GDNF delivery using human neural progenitor cells in a rat model of ALS Hum Gene Ther 16 2005 509 521
34. Y. Zhang, and W.M. Pardridge Conjugation of brain-derived neurotrophic factor to a blood-brain barrier drug targeting system enables neuroprotection in regional brain ischemia following intravenous injection of the neurotrophin Brain Res 889 2001 49 56
35. M.F. Pittenger, A.M. Mackay, S.C. Beck, R.K. Jaiswal, R. Douglas, and J.D. Mosca Multilineage potential of adult human mesenchymal stem cells Science 284 1999 143 147