Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide

Molecular Pharmacology

Volumn 78, Issue 5, 2010, Pages 943-951

  Eich, Marcus ^a   Roos, Wynand P ^a   Dianov, Grigory L ^b   Digweed, Martin ^c   Kaina, Bernd ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DACARBAZINE; METHYLNITRONITROSOGUANIDINE; MISMATCH REPAIR PROTEIN PMS2; NIBRIN; PROCARBAZINE; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; SMALL INTERFERING RNA; TEMOZOLOMIDE;

APOPTOSIS; ARTICLE; CELL DEATH; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; DRUG SENSITIVITY; FIBROBLAST; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; CASPASE 7; CELL CYCLE PROTEINS; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; DACARBAZINE; DNA METHYLATION; DRUG RESISTANCE, NEOPLASM; FIBROBLASTS; GUANINE; HOMOZYGOTE; HUMANS; MELANOMA; METHYLNITRONITROSOGUANIDINE; MUTAGENS; MUTATION; NECROSIS; NIJMEGEN BREAKAGE SYNDROME; NUCLEAR PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; UVEAL NEOPLASMS;

EID: 77958141341     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.066076     Document Type: Article

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