Long-term intermittent multiple micronutrient supplementation enhances hemoglobin and micronutrient status more than iron + folic acid supplementation in bangladeshi rural adolescent girls with nutritional anemia

Journal of Nutrition

Volumn 140, Issue 10, 2010, Pages 1879-1886

  Ahmed, Faruk ^a,b   Khan, Moududur R ^c   Akhtaruzzaman, Mohammad ^c   Karim, Rezaul ^c   Williams, Gail ^b   Torlesse, Harriet ^d   Darnton Hill, Ian ^e   Dalmiya, Nita ^d   Banu, Cadi P ^c   Nahar, Badrun ^c  

^a KUWAIT UNIVERSITY   (Kuwait)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF DHAKA   (Bangladesh)

^d UNICEF   (United States)

^e TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE; ASCORBIC ACID; FERRITIN; FOLIC ACID; HEMOGLOBIN; IRON; RETINOL; RIBOFLAVIN; TRACE ELEMENT;

ADOLESCENT; ANEMIA; ARTICLE; BANGLADESH; BLOOD SAMPLING; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; FERRITIN BLOOD LEVEL; HEMOGLOBINOPATHY; HUMAN; IRON DEFICIENCY ANEMIA; LONG TERM CARE; MAJOR CLINICAL STUDY; MICRONUTRIENT SUPPLEMENTATION; NUTRITIONAL STATUS; RANDOMIZED CONTROLLED TRIAL; RURAL AREA; SCHOOL CHILD; SUPPLEMENTATION; ASCORBIC ACID DEFICIENCY; BLOOD; COMPARATIVE STUDY; DIET SUPPLEMENTATION; IRON INTAKE; RETINOL DEFICIENCY; RIBOFLAVIN DEFICIENCY; RURAL POPULATION; TIME;

ADOLESCENT; ANEMIA; ANEMIA, IRON-DEFICIENCY; ASCORBIC ACID DEFICIENCY; BANGLADESH; CHILD; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; FOLIC ACID; HEMOGLOBINS; HUMANS; IRON, DIETARY; MICRONUTRIENTS; NUTRITIONAL STATUS; RIBOFLAVIN DEFICIENCY; RURAL POPULATION; TIME FACTORS; VITAMIN A DEFICIENCY;

EID: 77958130636     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.109.119123     Document Type: Article

References (46)

1. WHO. De Benoist B, McLean, Egli I, Cogswell M, editors. Worldwide prevalence of anaemia 1993-2005: WHO global database on anaemia. Geneva: WHO; 2008.
2. International Nutritional Anemia Consultative Group. Anaemia, iron deficiency and iron deficiency anaemia. Washington, DC: ILSI Human Nutrition Institute, INACG; 2002.
3. WHO. Guidelines for the control of iron deficiency in countries of the Eastern Mediterranean, Middle East and North Africa. WHO-EM/NUT/177, E/G/11. Geneva: WHO; 1996.
4. Mejia LA. Role of vitamin A in iron deficiency anaemia. In: Fomon SF, Zlotkin S, editors. Nutritional anaemias. Nestle Nutrition Workshop Series. Vevey: Nestle Ltd./New York: Raven Press; 1992. 30:93-101.
5. Powers HJ, Bates CJ, Duerden JM. Effect of riboflavin deficiency in rats on some aspect of iron metabolism. Int J Vitam Nutr Res. 1983;53:371-6.
6. Leklem JE. Vitamin B-6. In: Ziegler EE, Filer LJ Jr, editors. Present knowledge in nutrition. 7th ed. Washington, DC: ILSI Press; 1997. p. 174-83.
7. Fishman SM, Christian P, West KP Jr. The role of vitamins in the prevention and control of anaemia. Public Health Nutr. 2000;3:125-50.
8. Suharno D, Muhilal. Vitamin A and nutritional anaemia. Food Nutr Bull. 1996;17:7-10.
9. Lönnerdal B. Dietary factors affecting trace element absorption in infants. Acta Paediatr Scand Suppl. 1989;351:109-13.
10. Dreyfuss ML, Stoltzfus RJ, Shrestha JB, Pradhan EK, LeClerq SC, Khatry SK, Shrestha SR, Katz J, Albonico M, et al. Hookworm, malaria and vitamin A deficiency contribute to anemia and iron deficiency among pregnant women in the plains of Nepal. J Nutr. 2000;130:2527-36.
11. Jansson LT, Kling S, Dallman PH. Anemia in children with acute infection seen in a primary care pediatric outpatient clinic. Pediatr Infect Dis. 1986;5:424-7.
12. Linpisarn S, Tienboon P, Promtet N, Putsyaninunt P, Santawanpat S, Fushs GJ. Iron deficiency and anemia in children with a high prevalence of haemoglobinopathies: implications for screening. Int J Epidemiol. 1996;25:1262-6.
13. Bangladesh Bureau of Statistics/UNICEF. Anaemia prevalence survey of urban Bangladesh and rural Chittagong hill tracts 2003. Dhaka (Bangladesh): Bangladesh Bureau of Statistics and UNICEF; 2004.
14. Ahmed F. Anaemia in Bangladesh: a review of prevalence and aetiology. Public Health Nutr. 2000;3:385-93.
15. Ahmed F, Hasan N, Kabir Y. Vitamin A deficiency among adolescent garment factory workers in Bangladesh. Eur J Clin Nutr. 1997;51:698-702.
16. Ahmed F, Khan MR, Islam M, Kabir I, Fuch G. Anaemia and iron deficiency among adolescent schoolgirls in peri-urban Bangladesh. Eur J Clin Nutr. 2000;54:678-83.
17. Ahmed F, Khan MR, Jackson AA. Concomitant supplementation with vitamin A enhances response to weekly supplemental iron and folic acid in anaemic teenage women in urban Bangladesh. Am J Clin Nutr. 2001;74:108-15.
18. Ahmed F, Khan MR, Banu CP, Qazi MR, Akhteruzaman M. The coexistence of other multiple micronutrient deficiencies in anaemic adolescent schoolgirls in rural Bangladesh. Eur J Clin Nutr. 2008;62:365-72.
19. Allen LH, Rosado JL, Casterline JE, Lopez P, Garcia OP, Martinez H. Lack of hemoglobin response to iron supplementation in anemic Mexican preschoolers with multiple micronutrient deficiencies. Am J Clin Nutr. 2000;71:1485-94.
20. Ronnenberg AG, Goldman MB, Aitken IW, Xu X. Anemia and deficiencies of folate and vitamin B6 are common are common and vary with season in Chinese women of childbearing age. J Nutr. 2000;130:2703-10.
21. Dijkhuizen MA, Wieringa FT, West CE, Muherdiyantiningsih, Muhilal. Concurrent micronutrient deficiencies in lactating mothers and their infants in Indonesia. Am J Clin Nutr. 2001;73:786-91.
22. UNICEF/WHO/United Nations University. Composition of a multimicronutrient supplement to be used in pilot programmes among pregnant women in developing countries. New York: UNICEF/WHO/UNU; 1999.
23. Huffman SL, Baker J, Shumann J, Zehner ER. The case for promoting multiple vitamin/mineral supplementation for women of reproductive age in developing countries. Washington (DC): The Linkage Project, Academy for Educational Development; 1998.
24. Ahmed F, Khan MR, Akhtaruzzaman M, Karim R, Marks GC, Banu CP, Nahar B, Williams G. Efficacy of twice weekly multiple micronutrient supplementation for improving the haemoglobin and micronutrient status in anaemic adolescent schoolgirls in Bangladesh. Am J Clin Nutr. 2005;82:829-35.
25. Schultink W. Iron supplementation programs: compliance of target groups and frequency of tablet intake. Food Nutr Bull. 1996;17:22-6.
26. Yip R. Iron supplementation during pregnancy: is it effective? Am J Clin Nutr. 1996;63:853-5.
27. Tee E-S, Kandiah M, Awin N, Chong S, Satgunasingam N, Kamarudin L, Milani S, Dugdale AE, Vietri FE. School-administered weekly iron-folate supplements improve haemoglobin and ferritin concentrations in Malaysian adolescent girls. Am J Clin Nutr. 1999;69:1249-56.
28. Viteri FE, Ali F, Tujague J. Long term weekly iron supplementation improves and sustains nonpregnant women's iron status as well or better than currently recommended short-term daily supplementation. J Nutr. 1999;129:2013-20.
29. Angeles-Agdeppa I, Schltink W, Sastroamidjojo S, Gross R, Karyadi D. Weekly micronutrient supplementation to build iron stores in female Indonesian adolescents. Am J Clin Nutr. 1997;66:177-83.
30. Lowry OH, Lopez JA, Bessey OA. The determination of ascorbic acid in small amount of blood serum. J Biol Chem. 1945;160:609-15.
31. 6 in relation to anthropometry, haemoglobin, and albumin of newborn and their mothers from northeast Thailand. Int J Vitam Nutr Res. 1990;60:75-80.
32. WHO/UNICEF/United Nations University. Iron deficiency anemia, assessment, prevention and control: a guide for programme managers. WHO/NHD/01.3. Geneva: WHO; 2001
33. International Nutritional Anaemia Consultative Group. Measurement of iron status. A report of the INACG. Washington, DC: ILSI Research Foundation; 1985.
34. Jelliffe DB, Jelliffe EFP. Community nutritional assessment. Oxford: Oxford University Press; 1989.
35. WHO. Indicators of assessing vitamin A deficiency and their application in monitoring and evaluating intervention programmes. WHO/NUT/96.10. Geneva: WHO; 1996.
36. Ayoya MA, Spiekermann-Brouwer GM, Traore AK, Stoltzfus RJ, Habicht J-P, Garza C. Multiple micronutrients including iron are not more effective than iron alone for improving hemoglobin and iron status of Malian school children. J Nutr. 2009;139:1972-9.
37. Ramakrishnan U, Neufeld LM, Gonzalez-Cossio T, Villapando S, Garcia-Guerra A, Rivera J, Martorell R. Multiple micronutrient supplements during pregnancy do not reduce anemia or improve iron status compared to iron-only supplements in semirural Mexico. J Nutr. 2004;134:898-903.
38. Christian P, Shrestha J, LeClerq SC, Khatry SK, Jiang T, Wagner T, Katz J, West JP Jr. Supplementation with micronutrients in addition to iron and folic acid does not further improve the hematological status in pregnant women in rural Nepal. J Nutr. 2003;133:3492-8.
39. Moriarty-Craige SE, Ramakrisnan U, Neufeld L, Rivera J, Mortell R. Multivitamin-mineral supplementation is not as efficacious as is iron supplementation in improving hemoglobin concentrations in nonpregnant anemic women living in Mexico. Am J Clin Nutr. 2004;80:1308-11.
40. Shrimpton R, Huffman SL, Zehner ER, Darnton-Hill I, Dalmiya N. Micronutrient supplementation during pregnancy in developing country settings: policy and programme implications of the results of a meta-analysis. Food Nutr Bull. 2009;30:S556-73.
41. Gera T, Sachdev HP, Nestel P. Effect of combining multiple micronutrients with iron supplementation on Hb response in children: systematic review of randomized controlled trial. Public Health Nutr. 2009;12:756-73.
42. Thompson D, Milford-Ward A, Whicher JT. The value of acute phase protein measurements in clinical practice. Ann Clin Biochem. 1992;29:123-31.
43. Punnonen K, Irjala K, Rajamaki A. Serum transferrin and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood. 1997;89:1052-7.
44. Hyder SMZ, Haseen F, Khan M, Schaetzel T, Jalal CSB, Rahman M, Lonnerdal B, Manner V, Mehansho H. A multiple micronutrient fortified beverage affects hemoglobin, iron and vitamin A status and growth in adolescent girls in rural Bangladesh. J Nutr. 2007;137:2147-53.
45. Baker PN, Wheeler SJ, Sanders TA, Thomas JE, Hutchinson CJ, Clarke K, Berry JL, Jones RL, Seed PT, et al. A prospective study of micronutrient status in adolescent pregnancy. Am J Clin Nutr. 2009;89:1114-24.
46. National Institute of Population Research and Training/Mitra and Associates/ORC Macro. Bangladesh demographic and health survey 2004. Dhaka (Bangladesh) and Calverton (New York): National Institute of Population Research and Training, Mitra Associates, and ORC Macro; 2005.