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Volumn 99, Issue 4, 2010, Pages 255-262

Statins withdrawal, vascular complications, rebound effect and similitude

Author keywords

Homeopathy; Paradoxical reaction; Rebound effect; Secondary effect; Similitude; Statin; Substance withdrawal syndrome; Vascular diseases

Indexed keywords

ATORVASTATIN; CERIVASTATIN; CHOLESTEROL; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; NITRIC OXIDE; PLACEBO; PRAVASTATIN; SIMVASTATIN;

EID: 77958115678     PISSN: 14754916     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.homp.2010.01.001     Document Type: Article
Times cited : (22)

References (45)
  • 1
    • 0004063374 scopus 로고
    • [Boericke W, Trans.], B Jain Publishers, New Delhi
    • Hahnemann S. Organon of medicine 1991, [Boericke W, Trans.], B Jain Publishers, New Delhi. 6th edn.
    • (1991) Organon of medicine
    • Hahnemann, S.1
  • 3
    • 0032802653 scopus 로고    scopus 로고
    • Similitude in modern pharmacology
    • Teixeira M.Z. Similitude in modern pharmacology. Homeopathy 1999, 88(3):112-120.
    • (1999) Homeopathy , vol.88 , Issue.3 , pp. 112-120
    • Teixeira, M.Z.1
  • 4
    • 0037322551 scopus 로고    scopus 로고
    • Homeopathic use of modern medicines: utilisation of the curative rebound effect
    • Teixeira M.Z. Homeopathic use of modern medicines: utilisation of the curative rebound effect. Med Hypotheses 2003, 60(2):276-283.
    • (2003) Med Hypotheses , vol.60 , Issue.2 , pp. 276-283
    • Teixeira, M.Z.1
  • 5
    • 26844560879 scopus 로고    scopus 로고
    • 'Paradoxical strategy for treating chronic diseases': a therapeutic model used in homeopathy for more than two centuries
    • Teixeira M.Z. 'Paradoxical strategy for treating chronic diseases': a therapeutic model used in homeopathy for more than two centuries. Homeopathy 2005, 94(4):265-266.
    • (2005) Homeopathy , vol.94 , Issue.4 , pp. 265-266
    • Teixeira, M.Z.1
  • 6
    • 33749047860 scopus 로고    scopus 로고
    • Evidence of the principle of similitude in modern fatal iatrogenic events
    • Teixeira M.Z. Evidence of the principle of similitude in modern fatal iatrogenic events. Homeopathy 2006, 95(4):229-236.
    • (2006) Homeopathy , vol.95 , Issue.4 , pp. 229-236
    • Teixeira, M.Z.1
  • 7
    • 33846148713 scopus 로고    scopus 로고
    • NSAIDs, myocardial infarction, rebound effect and similitude
    • Teixeira M.Z. NSAIDs, myocardial infarction, rebound effect and similitude. Homeopathy 2007, 96(1):67-68.
    • (2007) Homeopathy , vol.96 , Issue.1 , pp. 67-68
    • Teixeira, M.Z.1
  • 8
    • 34147152787 scopus 로고    scopus 로고
    • Bronchodilators, fatal asthma, rebound effect and similitude
    • Teixeira M.Z. Bronchodilators, fatal asthma, rebound effect and similitude. Homeopathy 2007, 96(2):135-137.
    • (2007) Homeopathy , vol.96 , Issue.2 , pp. 135-137
    • Teixeira, M.Z.1
  • 9
    • 63549113234 scopus 로고    scopus 로고
    • Antidepressants, suicidality and rebound effect: evidence of similitude?
    • Teixeira M.Z. Antidepressants, suicidality and rebound effect: evidence of similitude?. Homeopathy 2009, 98(1):114-121.
    • (2009) Homeopathy , vol.98 , Issue.1 , pp. 114-121
    • Teixeira, M.Z.1
  • 10
    • 64749089721 scopus 로고    scopus 로고
    • Statins and cardiovascular diseases: from cholesterol lowering to pleiotropy
    • Zhou Q., Liao J.K. Statins and cardiovascular diseases: from cholesterol lowering to pleiotropy. Curr Pharm Des 2009, 15(5):467-478.
    • (2009) Curr Pharm Des , vol.15 , Issue.5 , pp. 467-478
    • Zhou, Q.1    Liao, J.K.2
  • 11
    • 63149166444 scopus 로고    scopus 로고
    • Statins and cardioprotection - more than just lipid lowering?
    • Ludman A., Venugopal V., Yellon D.M., Hausenloy D.J. Statins and cardioprotection - more than just lipid lowering?. Pharmacol Ther 2009, 122(1):30-43.
    • (2009) Pharmacol Ther , vol.122 , Issue.1 , pp. 30-43
    • Ludman, A.1    Venugopal, V.2    Yellon, D.M.3    Hausenloy, D.J.4
  • 12
    • 73349112590 scopus 로고    scopus 로고
    • Adverse effects of statins - mechanisms and consequences
    • Sep 1, [Epub ahead of print]
    • Bełtowski J., Wójcicka G., Jamroz-Wiśniewska A. Adverse effects of statins - mechanisms and consequences. Curr Drug Safety 2009 Sep 1, [Epub ahead of print].
    • (2009) Curr Drug Safety
    • Bełtowski, J.1    Wójcicka, G.2    Jamroz-Wiśniewska, A.3
  • 13
    • 33748996772 scopus 로고    scopus 로고
    • Discontinuation of statin treatment in stroke patients
    • Endres M., Laufs U. Discontinuation of statin treatment in stroke patients. Stroke 2006, 37(10):2640-2643.
    • (2006) Stroke , vol.37 , Issue.10 , pp. 2640-2643
    • Endres, M.1    Laufs, U.2
  • 14
    • 36949023522 scopus 로고    scopus 로고
    • A peri-operative statin update for non-cardiac surgery. Part I: the effects of statin therapy on atherosclerotic disease and lessons learnt from statin therapy in medical (non-surgical) patients
    • Biccard B.M. A peri-operative statin update for non-cardiac surgery. Part I: the effects of statin therapy on atherosclerotic disease and lessons learnt from statin therapy in medical (non-surgical) patients. Anaesthesia 2008, 63(1):52-64.
    • (2008) Anaesthesia , vol.63 , Issue.1 , pp. 52-64
    • Biccard, B.M.1
  • 15
    • 37549006788 scopus 로고    scopus 로고
    • Statins for surgical patients
    • Williams T.M., Harken A.H. Statins for surgical patients. Ann Surg 2008, 247(1):30-37.
    • (2008) Ann Surg , vol.247 , Issue.1 , pp. 30-37
    • Williams, T.M.1    Harken, A.H.2
  • 16
    • 64149114758 scopus 로고    scopus 로고
    • Lipid-lowering drugs in ischemic stroke prevention and their influence on acute stroke outcome
    • Fuentes B., Martínez-Sánchez P., Díez-Tejedor E. Lipid-lowering drugs in ischemic stroke prevention and their influence on acute stroke outcome. Cerebrovasc Dis 2009, 27(Suppl. 1):126-133.
    • (2009) Cerebrovasc Dis , vol.27 , Issue.SUPPL. 1 , pp. 126-133
    • Fuentes, B.1    Martínez-Sánchez, P.2    Díez-Tejedor, E.3
  • 17
    • 0024847925 scopus 로고
    • Lovastatin treatment inhibits sterol synthesis and induces HMG-CoA reductase activity in mononuclear leukocytes of normal subjects
    • Stone B.G., Evans C.D., Prigge W.F., Duane W.C., Gebhard R.L. Lovastatin treatment inhibits sterol synthesis and induces HMG-CoA reductase activity in mononuclear leukocytes of normal subjects. J Lipid Res 1989, 30(12):1943-1952.
    • (1989) J Lipid Res , vol.30 , Issue.12 , pp. 1943-1952
    • Stone, B.G.1    Evans, C.D.2    Prigge, W.F.3    Duane, W.C.4    Gebhard, R.L.5
  • 18
    • 0037388219 scopus 로고    scopus 로고
    • Residual effects of lovastatin and simvastatin on urinary mevalonate excretions in patients with familial hypercholesterolemia
    • Pappu A.S., Bacon S.P., Illingworth D.R. Residual effects of lovastatin and simvastatin on urinary mevalonate excretions in patients with familial hypercholesterolemia. J Lab Clin Med 2003, 141(4):250-256.
    • (2003) J Lab Clin Med , vol.141 , Issue.4 , pp. 250-256
    • Pappu, A.S.1    Bacon, S.P.2    Illingworth, D.R.3
  • 19
    • 33745759751 scopus 로고    scopus 로고
    • Effects of atorvastatin and atorvastatin withdrawal on soluble CD40L and adipocytokines in patients with hypercholesterolaemia
    • Chu C.S., Lee K.T., Lee M.Y., et al. Effects of atorvastatin and atorvastatin withdrawal on soluble CD40L and adipocytokines in patients with hypercholesterolaemia. Acta Cardiol 2006, 61(3):263-269.
    • (2006) Acta Cardiol , vol.61 , Issue.3 , pp. 263-269
    • Chu, C.S.1    Lee, K.T.2    Lee, M.Y.3
  • 20
    • 58149314288 scopus 로고    scopus 로고
    • Short-term withdrawal of simvastatin induces endothelial dysfunction in patients with coronary artery disease: a dose-response effect dependent on endothelial nitric oxide synthase
    • Chen H., Ren J.Y., Xing Y., et al. Short-term withdrawal of simvastatin induces endothelial dysfunction in patients with coronary artery disease: a dose-response effect dependent on endothelial nitric oxide synthase. Int J Cardiol 2009, 131(3):313-320.
    • (2009) Int J Cardiol , vol.131 , Issue.3 , pp. 313-320
    • Chen, H.1    Ren, J.Y.2    Xing, Y.3
  • 21
    • 0034687606 scopus 로고    scopus 로고
    • Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription
    • Laufs U., Endres M., Custodis F., et al. Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription. Circulation 2000, 102(25):3104-3110.
    • (2000) Circulation , vol.102 , Issue.25 , pp. 3104-3110
    • Laufs, U.1    Endres, M.2    Custodis, F.3
  • 22
    • 0037319355 scopus 로고    scopus 로고
    • Withdrawal of statin treatment abrogates stroke protection in mice
    • Gertz K., Laufs U., Lindauer U., et al. Withdrawal of statin treatment abrogates stroke protection in mice. Stroke 2003, 34(2):551-557.
    • (2003) Stroke , vol.34 , Issue.2 , pp. 551-557
    • Gertz, K.1    Laufs, U.2    Lindauer, U.3
  • 23
    • 36448973154 scopus 로고    scopus 로고
    • Effects of initiation and acute withdrawal of statins on the neurovascular coupling mechanism in healthy, normocholesterolemic humans
    • Rosengarten B., Auch D., Kaps M. Effects of initiation and acute withdrawal of statins on the neurovascular coupling mechanism in healthy, normocholesterolemic humans. Stroke 2007, 38(12):3193-3197.
    • (2007) Stroke , vol.38 , Issue.12 , pp. 3193-3197
    • Rosengarten, B.1    Auch, D.2    Kaps, M.3
  • 24
    • 5644240820 scopus 로고    scopus 로고
    • Effect of withdrawal of statin on C-reactive protein
    • Lee K.T., Lai W.T., Chu C.S., et al. Effect of withdrawal of statin on C-reactive protein. Cardiology 2004, 102(3):166-170.
    • (2004) Cardiology , vol.102 , Issue.3 , pp. 166-170
    • Lee, K.T.1    Lai, W.T.2    Chu, C.S.3
  • 25
    • 33644692289 scopus 로고    scopus 로고
    • Changes of plasma inflammatory markers after withdrawal of statin therapy in patients with hyperlipidemia
    • Li J.J., Li Y.S., Chu J.M., et al. Changes of plasma inflammatory markers after withdrawal of statin therapy in patients with hyperlipidemia. Clin Chim Acta 2006, 366(1-2):269-273.
    • (2006) Clin Chim Acta , vol.366 , Issue.1-2 , pp. 269-273
    • Li, J.J.1    Li, Y.S.2    Chu, J.M.3
  • 26
    • 33646465683 scopus 로고    scopus 로고
    • Correlation between inflammation and oxidative stress in normocholesterolemic coronary artery disease patients 'on' and 'off' atorvastatin for short time intervals
    • Thomas M.K., Narang D., Lakshmy R., Gupta R., Naik N., Maulik S.K. Correlation between inflammation and oxidative stress in normocholesterolemic coronary artery disease patients 'on' and 'off' atorvastatin for short time intervals. Cardiovasc Drugs Ther 2006, 20(1):37-44.
    • (2006) Cardiovasc Drugs Ther , vol.20 , Issue.1 , pp. 37-44
    • Thomas, M.K.1    Narang, D.2    Lakshmy, R.3    Gupta, R.4    Naik, N.5    Maulik, S.K.6
  • 27
    • 70350572370 scopus 로고    scopus 로고
    • Rebound inflammatory response during the acute phase of myocardial infarction after simvastatin withdrawal
    • Sposito A.C., Carvalho L.S., Cintra R.M., et al. Rebound inflammatory response during the acute phase of myocardial infarction after simvastatin withdrawal. Atherosclerosis 2009, 207(1):191-194.
    • (2009) Atherosclerosis , vol.207 , Issue.1 , pp. 191-194
    • Sposito, A.C.1    Carvalho, L.S.2    Cintra, R.M.3
  • 28
    • 10744228675 scopus 로고    scopus 로고
    • Platelet hyperactivity after statin treatment discontinuation
    • Puccetti L., Pasqui A.L., Pastorelli M., et al. Platelet hyperactivity after statin treatment discontinuation. Thromb Haemost 2003, 90(3):476-482.
    • (2003) Thromb Haemost , vol.90 , Issue.3 , pp. 476-482
    • Puccetti, L.1    Pasqui, A.L.2    Pastorelli, M.3
  • 29
    • 0037177167 scopus 로고    scopus 로고
    • Withdrawal of statins increases event rates in patients with acute coronary syndromes
    • Heeschen C., Hamm C.W., Laufs U., Snapinn S., Böhm M., White H.D. Withdrawal of statins increases event rates in patients with acute coronary syndromes. Circulation 2002, 105(12):1446-1452.
    • (2002) Circulation , vol.105 , Issue.12 , pp. 1446-1452
    • Heeschen, C.1    Hamm, C.W.2    Laufs, U.3    Snapinn, S.4    Böhm, M.5    White, H.D.6
  • 31
    • 6944240055 scopus 로고    scopus 로고
    • Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarction
    • Spencer F.A., Fonarow G.C., Frederick P.D., et al. Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarction. Arch Intern Med 2004, 164(19):2162-2168.
    • (2004) Arch Intern Med , vol.164 , Issue.19 , pp. 2162-2168
    • Spencer, F.A.1    Fonarow, G.C.2    Frederick, P.D.3
  • 32
    • 23944497531 scopus 로고    scopus 로고
    • Effect of statin use within the first 24 hours of admission for acute myocardial infarction on early morbidity and mortality
    • Fonarow G.C., Wright R.S., Spencer F.A., et al. Effect of statin use within the first 24 hours of admission for acute myocardial infarction on early morbidity and mortality. Am J Cardiol 2005, 96(5):611-616.
    • (2005) Am J Cardiol , vol.96 , Issue.5 , pp. 611-616
    • Fonarow, G.C.1    Wright, R.S.2    Spencer, F.A.3
  • 33
    • 34447251828 scopus 로고    scopus 로고
    • Effect of statin withdrawal on frequency of cardiac events after vascular surgery
    • Schouten O., Hoeks S.E., Welten G.M., et al. Effect of statin withdrawal on frequency of cardiac events after vascular surgery. Am J Cardiol 2007, 100(2):316-320.
    • (2007) Am J Cardiol , vol.100 , Issue.2 , pp. 316-320
    • Schouten, O.1    Hoeks, S.E.2    Welten, G.M.3
  • 34
    • 33748100587 scopus 로고    scopus 로고
    • Statin withdrawal: clinical implications and molecular mechanisms
    • Cubeddu L.X., Seamon M.J. Statin withdrawal: clinical implications and molecular mechanisms. Pharmacotherapy 2006, 26(9):1288-1296.
    • (2006) Pharmacotherapy , vol.26 , Issue.9 , pp. 1288-1296
    • Cubeddu, L.X.1    Seamon, M.J.2
  • 35
    • 68749105920 scopus 로고    scopus 로고
    • Withdrawal of statins and risk of subarachnoid hemorrhage
    • Jun 11, [Epub ahead of print]
    • Risselada R., Straatman H., van Kooten F., et al. Withdrawal of statins and risk of subarachnoid hemorrhage. Stroke 2009 Jun 11, [Epub ahead of print].
    • (2009) Stroke
    • Risselada, R.1    Straatman, H.2    van Kooten, F.3
  • 36
    • 0142012111 scopus 로고    scopus 로고
    • A retrospective analysis of the effect of noncompliance on time to first major adverse cardiac event in LIPS
    • Lesaffre E., Kocmanová D., Lemos P.A., Disco C.M., Serruys P.W. A retrospective analysis of the effect of noncompliance on time to first major adverse cardiac event in LIPS. Clin Ther 2003, 25(9):2431-2447.
    • (2003) Clin Ther , vol.25 , Issue.9 , pp. 2431-2447
    • Lesaffre, E.1    Kocmanová, D.2    Lemos, P.A.3    Disco, C.M.4    Serruys, P.W.5
  • 37
    • 34848915855 scopus 로고    scopus 로고
    • Discontinuation of statin therapy and clinical outcome after ischemic stroke
    • Colivicchi F., Bassi A., Santini M., Caltagirone C. Discontinuation of statin therapy and clinical outcome after ischemic stroke. Stroke 2007, 38(10):2652-2657.
    • (2007) Stroke , vol.38 , Issue.10 , pp. 2652-2657
    • Colivicchi, F.1    Bassi, A.2    Santini, M.3    Caltagirone, C.4
  • 38
    • 34548278923 scopus 로고    scopus 로고
    • Statin treatment withdrawal in ischemic stroke: a controlled randomized study
    • Blanco M., Nombela F., Castellanos M., et al. Statin treatment withdrawal in ischemic stroke: a controlled randomized study. Neurology 2007, 69(9):904-910.
    • (2007) Neurology , vol.69 , Issue.9 , pp. 904-910
    • Blanco, M.1    Nombela, F.2    Castellanos, M.3
  • 39
    • 77958141008 scopus 로고    scopus 로고
    • The $10 billion pill holds the fries, please. Lipitor, the cholesterol-lowering drug, has become the bestselling pharmaceutical in history.
    • Simons J. The $10 billion pill holds the fries, please. Lipitor, the cholesterol-lowering drug, has become the bestselling pharmaceutical in history. Here's how Pfizer did it. Fortune Mag 2003, Jan 20. Available from: http://money.cnn.com/magazines/fortune/fortune_archive/2003/01/20/335643/index.htm.
    • (2003) Here's how Pfizer did it. Fortune Mag, Jan 20. Available from:
    • Simons, J.1
  • 40
    • 77958138412 scopus 로고    scopus 로고
    • Can a drug that helps hearts be harmful to the brain? Wall St J 2008, Feb 13 Health. Available from:
    • Beck M. Can a drug that helps hearts be harmful to the brain? Wall St J 2008, Feb 13 Health. Available from: http://online.wsj.com/article/SB120277403869360595.html.html%3Fmod%3Dhome_health_right.
    • (2008)
    • Beck, M.1
  • 41
    • 18244371396 scopus 로고    scopus 로고
    • Persistence and determinants of statin therapy among middle-aged patients for primary and secondary prevention
    • Perreault S., Blais L., Lamarre D., et al. Persistence and determinants of statin therapy among middle-aged patients for primary and secondary prevention. Br J Clin Pharmacol 2005, 59(5):564-573.
    • (2005) Br J Clin Pharmacol , vol.59 , Issue.5 , pp. 564-573
    • Perreault, S.1    Blais, L.2    Lamarre, D.3
  • 42
    • 33846435728 scopus 로고    scopus 로고
    • Evaluation of the prescription and utilization patterns of statins in an Italian local health unit during the period 1994-2003
    • Deambrosis P., Saramin C., Terrazzani G., et al. Evaluation of the prescription and utilization patterns of statins in an Italian local health unit during the period 1994-2003. Eur J Clin Pharmacol 2007, 63(2):197-203.
    • (2007) Eur J Clin Pharmacol , vol.63 , Issue.2 , pp. 197-203
    • Deambrosis, P.1    Saramin, C.2    Terrazzani, G.3
  • 43
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • Ridker P.M., Danielson E., Fonseca F.A., et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 2008, 359(21):2195-2207.
    • (2008) N Engl J Med , vol.359 , Issue.21 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3
  • 44
    • 63649095045 scopus 로고    scopus 로고
    • Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial
    • Ridker P.M., Danielson E., Fonseca F.A., et al. Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet 2009, 373(9670):1175-1182.
    • (2009) Lancet , vol.373 , Issue.9670 , pp. 1175-1182
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3
  • 45
    • 69749097819 scopus 로고    scopus 로고
    • When statin therapy stops: implications for the patient
    • Daskalopoulou S.S. When statin therapy stops: implications for the patient. Curr Opin Cardiol 2009, 24(5):454-460.
    • (2009) Curr Opin Cardiol , vol.24 , Issue.5 , pp. 454-460
    • Daskalopoulou, S.S.1


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