Multi-scale simulation of L-selectin-PSGL-1-dependent homotypic leukocyte binding and rupture

Biomechanics and Modeling in Mechanobiology

Volumn 9, Issue 5, 2010, Pages 613-627

  Gupta, V K ^a   Sraj, Ihab A ^a   Konstantopoulos, Konstantinos ^b   Eggleton, Charles D ^a  

^a Baltimore County   (United States)

^b Johns Hopkins University   (United States)

Author keywords

Cell adhesion; Cell deformation; Immersed boundary method; Monte Carlo simulation; Receptor ligand bond kinetics

Indexed keywords

BINDING SITES; BOND LENGTH; ENDOTHELIAL CELLS; INTELLIGENT SYSTEMS; LIGANDS; MONTE CARLO METHODS; RATE CONSTANTS; TURBULENT FLOW;

BOND FORMATION; BOND RUPTURE; CELL DEFORMATION; CELLS ADHESION; IMMERSED BOUNDARY METHODS; L-SELECTIN; MONTE CARLO'S SIMULATION; MULTI-SCALE SIMULATION; RECEPTOR-LIGAND BOND KINETIC; RECEPTOR-LIGAND BONDS;

CELL ADHESION;

CELL SURFACE RECEPTOR; L SELECTIN; LIGAND; MEMBRANE PROTEIN; P SELECTIN LIGAND PROTEIN; P-SELECTIN LIGAND PROTEIN;

ARTICLE; COMPUTER SIMULATION; KINETICS; LEUKOCYTE; METABOLISM; PROTEIN BINDING;

COMPUTER SIMULATION; KINETICS; L-SELECTIN; LEUKOCYTES; LIGANDS; MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; RECEPTORS, CELL SURFACE;

EID: 77958096298     PISSN: 16177959     EISSN: 16822978     Source Type: Journal    
DOI: 10.1007/s10237-010-0201-2     Document Type: Article

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