LASSBio-294, a compound with inotropic and lusitropic activity, decreases cardiac remodeling and improves Ca2 influx into sarcoplasmic reticulum after myocardial infarction

American Journal of Hypertension

Volumn 23, Issue 11, 2010, Pages 1220-1227

  Costa, Daniele G ^a   Da Silva, Jaqueline S ^a   Kümmerle, Arthur E ^a   Sudo, Roberto T ^a   Landgraf, Sharon S ^a   Caruso Neves, Celso ^a   Fraga, Carlos A M ^a   De Lacerda Barreiro, Eliezer J ^a   Zapata Sudo, Gisele ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

blood pressure; Ca2+ regulation; cardiac remodeling; hypertension; LASSBio 294; myocardial infarction; skinned fibers; thienylhydrazone

Indexed keywords

3,4 METHYLENEDIOXYBENZOYL 2 THIENYLHYDRAZONE; CALCIUM ION; COLLAGEN; INOTROPIC AGENT; LASSBIO 294; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG ACTIVITY; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE PRESSURE; HEMODYNAMIC PARAMETERS; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM; TREATMENT RESPONSE;

ANIMALS; BLOOD PRESSURE; CALCIUM; CARDIOMEGALY; CARDIOTONIC AGENTS; DISEASE MODELS, ANIMAL; HYDRAZONES; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THIOPHENES; VENTRICULAR REMODELING;

EID: 77958093109     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1038/ajh.2010.157     Document Type: Article

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