Glutamate regulates eEF1A phosphorylation and ribosomal transit time in Bergmann glial cells

Neurochemistry International

Volumn 57, Issue 7, 2010, Pages 795-803

  Barrera, Iliana ^a   Flores Méndez, Marco ^a   Hernández Kelly, Luisa C ^a,b   Cid, Luis ^a   Huerta, Miriam ^a   Zinker, Samuel ^a   López Bayghen, Esther ^a   Aguilera, José ^b   Ortega, Arturo ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Bergmann glia; Gene expression regulation; Glutamate receptors; Signaling; Translation factors

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; ELONGATION FACTOR 1ALPHA; GLUTAMATE RECEPTOR; GLUTAMIC ACID; PHOSPHOTRANSFERASE INHIBITOR; POLYPEPTIDE; RAPAMYCIN;

ANIMAL CELL; ARTICLE; BERGMANN GLIAL CELL; CELL FUNCTION; CELL INTERACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; EMBRYO; GLIA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RIBOSOME TRANSIT TIME; TRANSLATION REGULATION;

ANIMALS; CELL COMMUNICATION; CELLS, CULTURED; CHICK EMBRYO; GLUTAMIC ACID; NEUROGLIA; PEPTIDE ELONGATION FACTOR 1; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN TRANSPORT; RATS; RECEPTORS, GLUTAMATE; RIBOSOMES; SIGNAL TRANSDUCTION; THREONINE; TIME FACTORS; TUMOR CELLS, CULTURED;

EUKARYOTA; VERTEBRATA;

EID: 77958085759     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2010.08.017     Document Type: Article

References (43)

1. Abe K., Saito H. Possible linkage between glutamate transporter and mitogen-activated protein kinase cascade in cultured rat cortical astrocytes. J. Neurochem. 2001, 76:217-223.
2. Aguirre A., Lopez T., Lopez-Bayghen E., Ortega A. Glutamate regulates kainate-binding protein expression in cultured chick Bergmann glia through an activator protein-1 binding site. J. Biol. Chem. 2000, 275:39246-39253.
3. Anthony T.E., Klein C., Fishell G., Heintz N. Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron 2004, 41:881-890.
4. Bak L.K., Schousboe A., Waagepetersen H.S. The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer. J. Neurochem. 2006, 98:641-653.
5. Balakrishnan S., Bellamy T.C. Depression of parallel and climbing fiber transmission to Bergmann glia is input specific and correlates with increased precision of synaptic transmission. Glia 2009, 57:393-401.
6. Barrera I., Hernandez-Kelly L.C., Castelan F., Ortega A. Glutamate-dependent elongation factor-2 phosphorylation in Bergmann glial cells. Neurochem. Int. 2008, 52:1167-1175.
7. Browne G.J., Proud C.G. Regulation of peptide-chain elongation in mammalian cells. Eur. J. Biochem. 2002, 269:5360-5368.
8. Gegelashvili M., Rodriguez-Kern A., Sung L., Shimamoto K., Gegelashvili G. Glutamate transporter GLAST/EAAT1 directs cell surface expression of FXYD2/gamma subunit of Na, K-ATPase in human fetal astrocytes. Neurochem. Int. 2007, 50:916-920.
9. Gonzalez-Mejia M.E., Morales M., Hernandez-Kelly L.C., Zepeda R.C., Bernabe A., Ortega A. Glutamate-dependent translational regulation in cultured Bergmann glia cells: involvement of p70S6K. Neuroscience 2006, 141:1389-1398.
10. Hansson E., Ronnback L. Astrocytes in glutamate neurotransmission. FASEB J. 1995, 9:343-350.
11. Haydon P.G., Blendy J., Moss S.J., Rob Jackson F. Astrocytic control of synaptic transmission and plasticity: a target for drugs of abuse?. Neuropharmacology 2009, 56(Suppl. 1):83-90.
12. Iino M., Goto K., Kakegawa W., Okado H., Sudo M., Ishiuchi S., Miwa A., Takayasu Y., Saito I., Tsuzuki K., Ozawa S. Glia-synapse interaction through Ca2+-permeable AMPA receptors in Bergmann glia. Science 2001, 292:926-929.
13. Inamura N., Nawa H., Takei N. Enhancement of translation elongation in neurons by brain-derived neurotrophic factor: implications for mammalian target of rapamycin signaling. J. Neurochem. 2005, 95:1438-1445.
14. Lehmann C., Bette S., Engele J. High extracellular glutamate modulates expression of glutamate transporters and glutamine synthetase in cultured astrocytes. Brain Res. 2009, 1297:1-8.
15. Lopez-Bayghen E., Aguirre A., Ortega A. Transcriptional regulation through glutamate receptors: Involvement of tyrosine kinases. J. Neurosci. Res. 2003, 74:717-725.
16. Lopez-Bayghen E., Ortega A. Glutamate-dependent transcriptional regulation of GLAST: role of PKC. J. Neurochem. 2004, 91:200-209.
17. Lopez-Bayghen E., Rosas S., Castelan F., Ortega A. Cerebellar Bergmann glia: an important model to study neuron-glia interactions. Neuron Glia Biol. 2007, 3:155-167.
18. Magistretti P.J. Role of glutamate in neuron-glia metabolic coupling. Am. J. Clin. Nutr. 2009, 90:875S-880S.
19. Malatesta P., Hack M.A., Hartfuss E., Kettenmann H., Klinkert W., Kirchhoff F., Gotz M. Neuronal or glial progeny: regional differences in radial glia fate. Neuron 2003, 37:751-764.
20. Matthews R.P., Guthrie C.R., Wailes L.M., Zhao X., Means A.R., McKnight G.S. Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Mol. Cell Biol. 1994, 14:6107-6116.
21. Millan A., Aguilar P., Mendez J.A., Arias-Montano J.A., Ortega A. Glutamate activates PP125(FAK) through AMPA/kainate receptors in Bergmann glia. J. Neurosci. Res. 2001, 66:723-729.
22. Millan A., Arias-Montano J.A., Mendez J.A., Hernandez-Kelly L.C., Ortega A. Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors signaling complexes in Bergmann glia. J. Neurosci. Res. 2004, 78:56-63.
23. Monnier A., Morales J., Cormier P., Boulben S., Belle R., Mulner-Lorillon O. Protein translation during early cell divisions of sea urchin embryos regulated at the level of polypeptide chain elongation and highly sensitive to natural polyamines. Zygote 2001, 9:229-236.
24. Morales M., Gonzalez-Mejia M.E., Bernabe A., Hernandez-Kelly L.C., Ortega A. Glutamate activates protein kinase B (PKB/Akt) through AMPA receptors in cultured Bergmann glia cells. Neurochem. Res. 2006, 31:423-429.
25. Nedergaard M., Rodriguez J.J., Verkhratsky A. Glial calcium and diseases of the nervous system. Cell Calcium 2010, 47:140-149.
26. Negrutskii B.S., El'skaya A.V. Eukaryotic translation elongation factor 1 alpha: structure, expression, functions, and possible role in aminoacyl-tRNA channeling. Prog. Nucleic Acid Res. Mol. Biol. 1998, 60:47-78.
27. Nielsen P.J., McConkey E.H. Evidence for control of protein synthesis in HeLa cells via the elongation rate. J. Cell Physiol. 1980, 104:269-281.
28. Ortega A., Eshhar N., Teichberg V.I. Properties of kainate receptor/channels on cultured Bergmann glia. Neuroscience 1991, 41:335-349.
29. Park S., Park J.M., Kim S., Kim J.A., Shepherd J.D., Smith-Hicks C.L., Chowdhury S., Kaufmann W., Kuhl D., Ryazanov A.G., Huganir R.L., Linden D.J., Worley P.F. Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron 2008, 59:70-83.
30. Petrushenko Z.M., Budkevich T.V., Shalak V.F., Negrutskii B.S., El'skaya A.V. Novel complexes of mammalian translation elongation factor eEF1A.GDP with uncharged tRNA and aminoacyl-tRNA synthetase. Implications for tRNA channeling. Eur. J. Biochem. 2002, 269:4811-4818.
31. Petrushenko Z.M., Negrutskii B.S., Ladokhin A.S., Budkevich T.V., Shalak V.F., El'skaya A.V. Evidence for the formation of an unusual ternary complex of rabbit liver EF-1alpha with GDP and deacylated tRNA. FEBS Lett. 1997, 407:13-17.
32. Redpath N.T., Foulstone E.J., Proud C.G. Regulation of translation elongation factor-2 by insulin via a rapamycin-sensitive signalling pathway. EMBO J. 1996, 15:2291-2297.
33. Rosas S., Vargas M.A., Lopez-Bayghen E., Ortega A. Glutamate-dependent transcriptional regulation of GLAST/EAAT1: a role for YY1. J. Neurochem. 2007, 101:1134-1144.
34. Roux P.P., Blenis J. ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 2004, 68:320-344.
35. Sager C., Tapken D., Kott S., Hollmann M. Functional modulation of AMPA receptors by transmembrane AMPA receptor regulatory proteins. Neuroscience 2009, 158:45-54.
36. Shin D., Park S., Park C. A splice variant acquiring an extra transcript leader region decreases the translation of glutamine synthetase gene. Biochem. J. 2003, 374:175-184.
37. Soderling T.R., Chang B., Brickey D. Cellular signaling through multifunctional Ca2+/calmodulin-dependent protein kinase II. J. Biol. Chem. 2001, 276:3719-3722.
38. Somogyi P., Eshhar N., Teichberg V.I., Roberts J.D. Subcellular localization of a putative kainate receptor in Bergmann glial cells using a monoclonal antibody in the chick and fish cerebellar cortex. Neuroscience 1990, 35:9-30.
39. Sonenberg N., Hinnebusch A.G. New modes of translational control in development, behavior, and disease. Mol. Cell 2007, 28:721-729.
40. Venema R.C., Peters H.I., Traugh J.A. Phosphorylation of valyl-tRNA synthetase and elongation factor 1 in response to phorbol esters is associated with stimulation of both activities. J. Biol. Chem. 1991, 266:11993-11998.
41. Watanabe M. Glial processes are glued to synapses via Ca(2+)-permeable glutamate receptors. Trends Neurosci. 2002, 25:5-6.
42. Wieronska J.M., Pilc A. Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs. Neurochem. Int. 2009, 55:85-97.
43. Zepeda R.C., Barrera I., Castelan F., Suarez-Pozos E., Melgarejo Y., Gonzalez-Mejia E., Hernandez-Kelly L.C., Lopez-Bayghen E., Aguilera J., Ortega A. Glutamate-dependent phosphorylation of the mammalian target of rapamycin (mTOR) in Bergmann glial cells. Neurochem. Int. 2009, 55:282-287.